TRNAU1AP

General Information

Gene Name : TRNAU1AP
Gene ID : ENSG00000180098.9
Essential Gene : Yes

Functions

tRNA regulation

Localization

Not Available

Domains (AlphaFold: TRNAU1AP)

RRM

Antibody Validation

GeneTex: GTX121631

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	TRNAU1AP	ENSG00000180098.9	21.66	19.41	20.54	ENCSR000AEF
HepG2	TRNAU1AP	ENSG00000180098.9	13.45	20.22	16.84	ENCSR985KAT
K562	TRNAU1AP	ENSG00000180098.9	33.20	29.54	31.37	ENCSR000AEO

Assays

5 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Controls	Method	Note
knockdown followed by RNA-seq	TRNAU1AP-BGKcLV06-K562	ENCSR889MBF	TRNAU1AP	K562	Released	ENCSR341TTW	CRISPR	KD% = 83.7,70.6
knockdown followed by RNA-seq	TRNAU1AP-BGHcLV10-HepG2	ENCSR481AIB	TRNAU1AP	HepG2	Released	ENCSR775ZWO	CRISPR	KD% = 58.6,53.2
knockdown followed by RNA-seq	TRNAU1AP-BG293LV03-WT293		TRNAU1AP	293T	Released		shRNA	KD% = ,
knockdown followed by RNA-seq	TRNAU1AP-BG293LV06-WT293		TRNAU1AP	293T	Released		shRNA	KD% = ,
RNA Bind-n-Seq	RBNS: TRNAU1AP	ENCSR419XDN	TRNAU1AP	cell-free sample	Released	ENCSR837OWO

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
TRNAU1AP	ENCAB780SOA	GTX121631	40863		Released, ENCODE3	Released, ENCODE3	BGHcLV10-51, Released, ENCODE4	BGKcLV06-39, Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
TRNAU1AP	K562	CRISPR	ENCSR889MBF	ENCSR341TTW	TRNAU1AP-BGKcLV06-39,TRNAU1AP-BGKcLV06-40	NT-BGKcLV06-1,NT-BGKcLV06-2	83.7,70.6	Released	ENCODE3
TRNAU1AP	HepG2	CRISPR			BGHcLV07-39,BGHcLV07-40	BGHcLV07-1,BGHcLV07-2	0.0,0.0	NotSatisfied	ENCODE3
TRNAU1AP	HepG2	CRISPR			BGHcLV09-25,BGHcLV09-26	BGHcLV09-1,BGHcLV09-2	54.8,52.5	NotSatisfied	ENCODE4
TRNAU1AP	HepG2	CRISPR	ENCSR481AIB	ENCSR775ZWO	TRNAU1AP-BGHcLV10-51,TRNAU1AP-BGHcLV10-52	NT-BGHcLV10-1,NT-BGHcLV10-2	58.6,53.2	Released	ENCODE4
TRNAU1AP	Ribo-STAMP-293T	shRNA			BGRSLV05-29,BGRSLV05-30	BGRSLV05-1,BGRSLV05-2		NotSatisfied	ENCORE2
TRNAU1AP	293T	shRNA			BG293LV03-23,BG293LV03-24	BG293LV03-1,BG293LV03-2		NotSatisfied	ENCORE2
TRNAU1AP	293T	shRNA			TRNAU1AP-BG293LV03-25,TRNAU1AP-BG293LV03-26	NT-BG293LV03-1,NT-BG293LV03-2	,	Released	ENCORE2
TRNAU1AP	293T	shRNA			TRNAU1AP-BG293LV06-31B,TRNAU1AP-BG293LV06-32B	NT-BG293LV06-1B,NT-BG293LV06-2B	,	Released	ENCORE2

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
TRNAU1AP	TRNAU1AP		Released	ENCODE3

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
TRNAU1AP	Product_ID: GTX121631 Lot_ID: 40863 Source: GeneTex Target Name: TRNAU1AP-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for TRNAU1AP is not avaliable on ENCORE database.

The binding motifs of TRNAU1AP

Proteins bound to RNA

TRNAU1AP RNA is bound by 19 proteins.

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eCLIP assay for TRNAU1AP is not avaliable on ENCORE database.

19 proteins are bound to TRNAU1AP RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	28898411	28898486	+	CDS,intron-Proximal	6.70265	43.84837	K562	AQR
chr1	28880172	28880244	+	CDS	3.12617	12.58821	K562	DDX3X
chr1	28887822	28887964	+	CDS,intron-Proximal	4.52590	10.98561	K562	PRPF8
chr1	28898391	28898490	+	CDS,intron-Proximal	3.63577	10.15139	K562	EFTUD2
chr1	28891324	28891439	+	CDS,intron-Proximal	3.41066	9.64125	K562	PRPF8
chr1	28903987	28904058	+	CDS,intron-Proximal	3.87488	9.59600	K562	AQR
chr1	28891628	28891727	+	intron-Distal	3.49785	9.20352	K562	KHSRP
chr1	28880151	28880172	+	CDS,intron-Proximal	3.82977	8.96385	K562	DDX3X
chr1	28887820	28887930	+	CDS,intron-Proximal	4.30809	8.66247	K562	EFTUD2
chr1	28893480	28893544	+	intron-Distal	4.06086	8.64802	HepG2	U2AF2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 48 entries

eCLIP assay for TRNAU1AP is not avaliable on ENCORE database.

Diffrential Expression

292 differentially expressed genes after Knockdown/Knockout TRNAU1AP protein.

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55 RBPs can affect the levels of TRNAU1AP.

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292 differentially expressed genes after Knockdown/Knockout TRNAU1AP protein :

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Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RPAP2	ENSG00000122484.8	101.02050	376.33530	-1.89740	18.92250	15.02230	K562	TRNAU1AP
SLC2A3	ENSG00000059804.11	2894.79130	5143.37600	-0.82930	12.58700	8.98780	K562	TRNAU1AP
TMSB10	ENSG00000034510.4	2434.27030	4180.38890	-0.78010	10.21100	7.00970	K562	TRNAU1AP
FANCL	ENSG00000115392.7	139.11810	344.18020	-1.30690	9.75300	6.60610	K562	TRNAU1AP
KIF21B	ENSG00000116852.10	488.52320	924.94600	-0.92090	9.34560	6.25990	K562	TRNAU1AP
RPS12	ENSG00000112306.7	7426.58900	11877.27780	-0.67740	8.69370	5.67810	K562	TRNAU1AP
GALE	ENSG00000117308.10	364.01010	692.37300	-0.92760	8.55700	5.55990	K562	TRNAU1AP
LGALS1	ENSG00000100097.7	637.54410	1139.40150	-0.83770	8.31920	5.35680	K562	TRNAU1AP
MCAM	ENSG00000076706.10	1096.30910	1840.94290	-0.74780	8.27500	5.32900	K562	TRNAU1AP
ENO1	ENSG00000074800.9	30061.26500	46050.69060	-0.61530	7.77190	4.91310	K562	TRNAU1AP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

55 RBPs can affect the gene expression of TRNAU1AP :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TRNAU1AP	ENSG00000180098.5	153.43370	308.04150	-1.00550	9.91910	8.81720	HepG2	CKAP4
TRNAU1AP	ENSG00000180098.5	303.04040	488.73840	-0.68960	8.02400	7.12320	HepG2	PUM1
TRNAU1AP	ENSG00000180098.5	84.00300	200.44870	-1.25470	8.09810	7.11100	HepG2	RPS19
TRNAU1AP	ENSG00000180098.5	323.77030	550.79950	-0.76660	8.35640	6.82750	K562	SF3B4
TRNAU1AP	ENSG00000180098.5	147.51110	268.68780	-0.86510	6.90520	5.98560	HepG2	HNRNPU
TRNAU1AP	ENSG00000180098.5	432.41290	671.03890	-0.63400	7.05450	5.62650	K562	HNRNPU
TRNAU1AP	ENSG00000180098.5	270.41410	460.40240	-0.76770	6.47610	5.61550	HepG2	PUF60
TRNAU1AP	ENSG00000180098.5	805.18590	498.14270	0.69270	7.00210	5.58720	K562	PPIG
TRNAU1AP	ENSG00000180098.5	337.86160	516.98340	-0.61370	6.22990	5.36460	HepG2	SUCLG1
TRNAU1AP	ENSG00000180098.5	189.67420	351.40230	-0.88960	5.94980	4.99930	HepG2	MAGOH
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 61 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for TRNAU1AP is not available on ENCORE database.

20 RBPs can affect the splicing of TRNAU1AP :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	TRNAU1AP	ENSG00000180098.5	chr1	+	28887624	28887772	28887144	28887244	28887857	28887910	0.08900	0.00000	0.00516	included	K562	EXOSC5
SE	TRNAU1AP	ENSG00000180098.5	chr1	+	28887624	28887772	28887144	28887244	28887857	28887910	-0.15500	0.00000	0.00001	excluded	HepG2	SRSF1
A3SS	TRNAU1AP	ENSG00000180098.5	chr1	+	28887834	28887910	28887857	28887910	28887144	28887244	0.19000	0.00000	0.00000	longer	K562	AQR
RI	TRNAU1AP	ENSG00000180098.5	chr1	+	28887144	28887910	28887144	28887244	28887857	28887910	0.19600	0.00000	0.00000	included	K562	AQR
RI	TRNAU1AP	ENSG00000180098.5	chr1	+	28887144	28887910	28887144	28887244	28887857	28887910	-0.13800	0.00002	0.00904	excluded	HepG2	ILF3
SE	TRNAU1AP	ENSG00000180098.5	chr1	+	28887624	28887772	28887144	28887244	28887857	28887910	0.12200	0.00004	0.00069	included	K562	AQR
SE	TRNAU1AP	ENSG00000180098.5	chr1	+	28887624	28887772	28887144	28887244	28887857	28887910	0.11500	0.00006	0.02050	included	K562	HNRNPA1
SE	TRNAU1AP	ENSG00000180098.5	chr1	+	28887624	28887772	28887144	28887244	28887857	28887910	0.06900	0.00007	0.04978	included	K562	UTP3
SE	TRNAU1AP	ENSG00000180098.5	chr1	+	28887624	28887772	28887144	28887244	28887857	28887910	0.06000	0.00010	0.01141	included	K562	HNRNPL
SE	TRNAU1AP	ENSG00000180098.5	chr1	+	28887624	28887772	28887144	28887244	28887857	28887910	0.19100	0.00010	0.04653	included	HepG2	BCCIP

Showing 1 to 10 of 25 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

TRNAU1AP

General Information

Functions

Localization

Domains (AlphaFold: TRNAU1AP)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for TRNAU1AP is not avaliable on ENCORE database.

19 proteins are bound to TRNAU1AP RNA:

eCLIP assay for TRNAU1AP is not avaliable on ENCORE database.

Diffrential Expression

292 differentially expressed genes after Knockdown/Knockout TRNAU1AP protein :

55 RBPs can affect the gene expression of TRNAU1AP :

The Knockdown/knockout RNA-Seq assay for TRNAU1AP is not available on ENCORE database.

20 RBPs can affect the splicing of TRNAU1AP :

The Knockdown/knockout RNA-Seq assay for TRNAU1AP is not avaliable on ENCORE database.