KLF3

General Information

Gene Name       : KLF3
Gene ID             : ENSG00000109787.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KLF3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KLF3ENSG00000109787.123.102.812.96ENCSR000AEF
HepG2KLF3ENSG00000109787.1216.2922.7119.50ENCSR985KAT
K562KLF3ENSG00000109787.1225.1023.7824.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KLF3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KLF3 RNA is bound by 37 proteins.  







eCLIP assay for KLF3 is not avaliable on ENCORE database.





37 proteins are bound to KLF3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr43869911338699153+3'-UTR4.250304.02104HepG2TIA1
chr43870233838702390+3'-UTR5.360048.15847K562PUM2
chr43868216038682246+3'-UTR,5'-UTR,intron-Proximal4.353013.93614HepG2AQR
chr43870064438700732+3'-UTR4.270828.68778K562PUM2
chr43869215338692291+3'-UTR,intron-Distal3.204456.25285HepG2KHSRP
chr43869886538698953+3'-UTR,CDS3.765503.45687HepG2IGF2BP3
chr43870215838702219+3'-UTR3.512974.20072K562IGF2BP1
chr43869151338691579+3'-UTR,intron-Proximal3.050735.39266HepG2GRWD1
chr43869875538698904+3'-UTR,CDS4.6352620.87981K562YBX3
chr43869161338691651+3'-UTR,intron-Distal3.489416.35478K562YBX3
chr43869150238691561+3'-UTR,intron-Proximal3.054953.67092K562PRPF8
chr43869911438699181+3'-UTR3.165055.08461K562IGF2BP1
chr43870211338702158+3'-UTR3.940313.31904K562IGF2BP1
chr43868216838682224+3'-UTR,5'-UTR,intron-Proximal3.732954.35521HepG2BUD13
chr43870009038700179+3'-UTR4.7628519.40723K562PUM2
chr43869157038691645+3'-UTR,intron-Distal,intron-Proximal4.002197.36824K562RBM15
chr43870187038701943+3'-UTR3.6871011.93954K562PUM2
chr43869215838692213+3'-UTR,intron-Distal3.166075.78064K562KHSRP
chr43869155738691655+3'-UTR,intron-Distal,intron-Proximal4.724045.59156HepG2RBM15
chr43869152038691663+3'-UTR,intron-Distal,intron-Proximal3.929803.15171K562SRSF1
chr43869978538699842+3'-UTR3.556564.94406K562YBX3
chr43869236238692424+3'-UTR,intron-Distal,polyA_site3.206664.05586HepG2U2AF2
chr43866607838666112+5'-UTR,intron-Proximal4.2289013.09382K562AQR
chr43866594138666029+5'-UTR3.535187.91814HepG2DDX3X
chr43866600238666034+5'-UTR3.890193.93112K562RBM15
chr43866585438665937+5'-UTR5.4175133.07084HepG2DDX3X
chr43866582338665935+5'-UTR3.402179.83669HepG2NCBP2
chr43866607938666142+5'-UTR,intron-Proximal6.3760013.59033HepG2AQR
chr43866604438666084+5'-UTR,intron-Proximal3.070857.19943K562YBX3
chr43869020538690215+CDS,intron-Proximal3.493808.04783K562YBX3
chr43869068138690736+CDS,intron-Proximal5.044946.35567HepG2PRPF8
chr43869046838690525+CDS3.721329.16948K562IGF2BP2
chr43868227238682350+CDS,intron-Proximal3.955284.45914HepG2PRPF8
chr43869046338690544+CDS3.184546.56546K562RBM15
chr43869636738696420+CDS3.545608.21916K562YBX3
chr43869021538690247+CDS4.1031212.97102K562YBX3
chr43869627838696398+CDS,intron-Proximal4.565267.60779HepG2AQR
chr43869022538690313+CDS4.589065.01312K562UCHL5
chr43869138438691454+CDS4.570855.54754K562IGF2BP1
chr43869038738690451+CDS3.417006.25289K562IGF2BP1
chr43869045738690569+CDS3.613764.66813HepG2RBM15
chr43869024738690279+CDS3.831958.43159K562YBX3
chr43869052638690613+CDS3.8371512.19338K562IGF2BP2
chr43869133838691417+CDS,intron-Proximal4.353013.93614HepG2AQR
chr43868224938682306+CDS,intron-Proximal4.033764.23295HepG2GRWD1
chr43866722038667286+intron-Distal3.015383.50680HepG2CSTF2
chr43866629338666406+intron-Distal3.049673.81808HepG2GTF2F1
chr43866681338666871+intron-Distal3.669738.40551K562NOLC1
chr43866629338666440+intron-Distal3.9779810.86322K562GEMIN5
chr43866640938666458+intron-Distal3.658835.56645HepG2CSTF2T
chr43866680738666874+intron-Distal4.538894.23759K562NONO
chr43866681438666881+intron-Distal3.324437.92133HepG2NKRF
chr43866687638666898+intron-Distal4.977655.17013K562RBM15
chr43866632838666455+intron-Distal4.270076.16184K562XRN2
chr43866680538666883+intron-Distal3.832693.42950K562DDX6
chr43869238738692431+intron-Distal4.763966.16300K562FMR1
chr43866632238666384+intron-Distal3.084553.42218HepG2XRN2
chr43866686938666876+intron-Distal3.848123.34231K562RBM15
chr43867439338674493+intron-Distal3.041305.21373HepG2PRPF4
chr43866617838666243+intron-Distal,intron-Proximal3.917583.63122HepG2PRPF4
chr43867948138679534+intron-Distal4.301963.72755K562EIF4G2
chr43866624138666302+intron-Distal4.036477.13178K562CSTF2T
chr43866618638666278+intron-Distal4.006717.33150K562FASTKD2
chr43869607238696171+intron-Distal4.049713.01017K562CPSF6
chr43866631638666409+intron-Distal3.2948911.02966HepG2CSTF2T
chr43866689838666915+intron-Distal4.747314.48994K562RBM15
chr43866661938666668+intron-Distal3.112533.89082K562TIA1
chr43866681038666901+intron-Distal5.593167.72885K562DDX24
chr43866620538666257+intron-Distal3.445637.19609HepG2EFTUD2
chr43869238338692435+intron-Distal3.654874.25110K562CSTF2T
chr43866680038666890+intron-Distal4.003413.10243K562SLTM
chr43869238638692428+intron-Distal4.071643.88460HepG2PCBP2
chr43867437738674509+intron-Distal3.197454.27427HepG2CSTF2T
chr43866641638666454+intron-Distal3.240403.04831K562RBM15
chr43866716838667276+intron-Distal3.490483.33412HepG2HNRNPL
chr43866638438666447+intron-Distal3.410983.89666HepG2XRN2
chr43866630238666384+intron-Distal3.054057.80457K562CSTF2T
chr43866633638666444+intron-Distal4.3578915.67497K562DROSHA
chr43866630638666377+intron-Distal3.718964.75609K562NCBP2
chr43866617838666282+intron-Distal,intron-Proximal3.001214.71322K562BUD13
chr43866616538666250+intron-Distal,intron-Proximal3.512596.18008K562GEMIN5
chr43866681638666865+intron-Distal3.001383.49427K562RBM15
chr43869069238690770+intron-Proximal5.566319.41643K562AQR
chr43866611238666130+intron-Proximal5.1385013.23057K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KLF3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KLF3 is not available on ENCORE database.

  • 90 RBPs can affect the levels of KLF3.  








The Knockdown/knockout RNA-Seq assay for KLF3 is not available on ENCORE database.





90 RBPs can affect the gene expression of KLF3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KLF3ENSG00000109787.81842.366002165.33840-0.233003.030502.39920HepG2ACO1
KLF3ENSG00000109787.81975.650103742.76890-0.9218012.8138011.75720HepG2AKAP1
KLF3ENSG00000109787.81071.146601735.73670-0.696406.082604.66720HepG2BCCIP
KLF3ENSG00000109787.83724.408602942.232600.340002.800902.02390HepG2CIRBP
KLF3ENSG00000109787.82448.449202165.004400.177402.226501.62030HepG2CKAP4
KLF3ENSG00000109787.82014.878903097.69240-0.620504.200803.25320HepG2CNOT7
KLF3ENSG00000109787.82015.043102401.42330-0.253103.119902.44520HepG2CELF1
KLF3ENSG00000109787.82448.672001697.295600.528707.654506.14790HepG2DDX24
KLF3ENSG00000109787.82251.750103585.40490-0.671108.357107.31920HepG2DDX3X
KLF3ENSG00000109787.84619.665303242.214100.510702.634701.68300HepG2DDX59
KLF3ENSG00000109787.82203.957301597.226600.464403.239202.03210HepG2AGO1
KLF3ENSG00000109787.82124.741001638.062600.375204.112102.82210HepG2EIF3G
KLF3ENSG00000109787.83017.043102547.448900.244002.900402.04730HepG2EIF4G1
KLF3ENSG00000109787.85266.326803502.407400.5884018.6150017.28640HepG2ETF1
KLF3ENSG00000109787.82616.588502116.043800.306202.966102.10440HepG2EWSR1
KLF3ENSG00000109787.81197.805801494.53540-0.319302.964601.74840HepG2FAM120A
KLF3ENSG00000109787.82484.796601971.671000.333603.227802.38350HepG2FUBP3
KLF3ENSG00000109787.82489.966403301.10960-0.406803.594202.81230HepG2FXR1
KLF3ENSG00000109787.82296.025103062.47100-0.415603.326502.60170HepG2G3BP1
KLF3ENSG00000109787.81711.745702867.55110-0.744406.424404.72980HepG2GRSF1
KLF3ENSG00000109787.82727.945202067.361200.399907.611606.09160HepG2HDGF
KLF3ENSG00000109787.82542.523403100.54430-0.286302.245501.61190HepG2HNRNPK
KLF3ENSG00000109787.84030.783003088.754500.383903.617702.90790HepG2HNRNPLL
KLF3ENSG00000109787.81804.689202364.31850-0.389704.040202.91070HepG2HNRNPM
KLF3ENSG00000109787.81299.558702012.14450-0.6307015.7739014.42350HepG2HNRNPU
KLF3ENSG00000109787.82194.421203019.89620-0.460702.828101.48960HepG2ILF3
KLF3ENSG00000109787.82223.939102951.60720-0.408402.773501.58250HepG2KHDRBS1
KLF3ENSG00000109787.82507.836503811.27200-0.603804.830403.17230HepG2KRR1
KLF3ENSG00000109787.82425.468703320.80690-0.453303.735803.01250HepG2MATR3
KLF3ENSG00000109787.82298.644902773.60520-0.271002.038601.33950HepG2MSI2
KLF3ENSG00000109787.81757.643803399.08270-0.9515015.0460013.64950HepG2NCBP2
KLF3ENSG00000109787.81937.976302560.64480-0.402005.923804.81060HepG2NOL12
KLF3ENSG00000109787.84664.715802738.706900.7682013.7709012.23630HepG2NSUN2
KLF3ENSG00000109787.82235.274402945.87170-0.398206.661005.78120HepG2PCBP1
KLF3ENSG00000109787.82120.408901794.673400.240502.465701.76550HepG2PPIL4
KLF3ENSG00000109787.82888.118102434.222500.246602.080801.40140HepG2PRPF4
KLF3ENSG00000109787.8986.807001316.84530-0.416202.617401.83020HepG2PRPF8
KLF3ENSG00000109787.81938.136402997.39510-0.6290013.8321012.79280HepG2PTBP1
KLF3ENSG00000109787.81900.385802205.55760-0.214902.665202.05670HepG2PUS1
KLF3ENSG00000109787.82286.194003246.55020-0.506009.538908.47960HepG2QKI
KLF3ENSG00000109787.82092.459402927.39340-0.484408.903208.09530HepG2RBM22
KLF3ENSG00000109787.83644.027202946.340600.306503.043402.33990HepG2RBM25
KLF3ENSG00000109787.82782.246003335.92890-0.261803.159302.58860HepG2NELFE
KLF3ENSG00000109787.82642.670103106.75410-0.233402.921002.28930HepG2RECQL
KLF3ENSG00000109787.84142.137503057.308100.438005.011404.08440HepG2SF3B1
KLF3ENSG00000109787.82707.956302343.540300.208402.810702.10320HepG2SLBP
KLF3ENSG00000109787.81807.160202089.67500-0.209602.827902.17800HepG2SMN1
KLF3ENSG00000109787.82322.991203257.46830-0.487809.469808.71280HepG2SRSF1
KLF3ENSG00000109787.82321.128302650.03600-0.191202.287901.77590HepG2SRSF9
KLF3ENSG00000109787.82076.329702705.77270-0.382002.352601.35120HepG2STIP1
KLF3ENSG00000109787.82799.653401962.161700.512703.259401.95010HepG2SUB1
KLF3ENSG00000109787.82283.412701698.927200.426503.771402.99940HepG2SUPV3L1
KLF3ENSG00000109787.82521.194402927.65620-0.215602.017001.52540HepG2TAF15
KLF3ENSG00000109787.81287.675501955.20240-0.6025010.148009.29510HepG2TIAL1
KLF3ENSG00000109787.82343.705602931.20370-0.322702.312601.73330HepG2U2AF1
KLF3ENSG00000109787.82634.904903131.39810-0.249103.813303.01370HepG2UPF1
KLF3ENSG00000109787.81272.884201672.40400-0.393802.477101.78760HepG2XRN2
KLF3ENSG00000109787.81677.268201072.808600.644607.644705.66260K562CCAR1
KLF3ENSG00000109787.85208.318004392.285300.245703.047202.02520K562CELF1
KLF3ENSG00000109787.85844.753703499.953400.7397027.3793025.53650K562DDX47
KLF3ENSG00000109787.81971.317301201.024200.714809.261006.70140K562DHX30
KLF3ENSG00000109787.81864.894201222.838600.608803.225201.32070K562DNAJC2
KLF3ENSG00000109787.82559.551501691.416000.597605.285403.47760K562EEF2
KLF3ENSG00000109787.81751.176502527.00580-0.529108.621807.45830K562EIF2S2
KLF3ENSG00000109787.81967.659801091.225300.850406.715105.09350K562EIF3A
KLF3ENSG00000109787.82068.831101533.289400.432106.347705.15920K562EIF3G
KLF3ENSG00000109787.81690.717601356.359700.317802.568101.77790K562EIF4A3
KLF3ENSG00000109787.81547.860301221.464200.341603.817402.42710K562EIF4B
KLF3ENSG00000109787.85290.811203572.869500.5663012.3075010.40390K562EIF4G2
KLF3ENSG00000109787.81816.814001410.555000.365004.864004.09270K562FXR1
KLF3ENSG00000109787.81912.957101213.197100.656905.629704.54030K562G3BP2
KLF3ENSG00000109787.83191.592602279.311600.485606.361404.67120K562GLRX3
KLF3ENSG00000109787.81869.853403367.74370-0.8489013.4649011.77850K562GRSF1
KLF3ENSG00000109787.82293.248701725.678200.410104.779404.01550K562HNRNPC
KLF3ENSG00000109787.81807.042702572.75600-0.509704.798603.53760K562HNRNPM
KLF3ENSG00000109787.84420.201603062.557100.529302.817901.38300K562ILF2
KLF3ENSG00000109787.81478.611801120.853000.399503.137101.53730K562ILF3
KLF3ENSG00000109787.81416.524701083.148100.387002.919401.39460K562KHDRBS1
KLF3ENSG00000109787.82092.795601693.936600.305002.865901.92590K562MATR3
KLF3ENSG00000109787.82414.673802992.49160-0.309502.929202.02660K562METAP2
KLF3ENSG00000109787.83474.537502662.691200.3838011.4037010.03190K562NSUN2
KLF3ENSG00000109787.84405.250903221.923400.451202.505801.34440K562PABPC1
KLF3ENSG00000109787.81214.439701510.25200-0.314502.483501.55900K562PCBP2
KLF3ENSG00000109787.82623.967803550.79560-0.436404.686803.57950K562PPIG
KLF3ENSG00000109787.81255.226901649.09190-0.393704.248003.44160K562PTBP1
KLF3ENSG00000109787.84593.886903898.378400.236702.146401.42890K562PUF60
KLF3ENSG00000109787.85104.100204145.770500.299904.244402.90040K562PUM1
KLF3ENSG00000109787.82097.747701619.875900.372902.616301.82460K562RPS19
KLF3ENSG00000109787.84541.798102992.113400.602004.153602.18820K562RPS3A
KLF3ENSG00000109787.82803.411502014.985300.476304.806903.37790K562SAFB
KLF3ENSG00000109787.82961.283102083.059500.507403.924402.18350K562SDAD1
KLF3ENSG00000109787.83392.745302627.254300.368806.057904.88800K562SF3A3
KLF3ENSG00000109787.81493.444801261.982400.242902.053401.31870K562SF3B4
KLF3ENSG00000109787.81626.626901181.562700.461104.474502.82330K562SLBP
KLF3ENSG00000109787.83043.502302691.665900.177102.309201.44570K562SRPK2
KLF3ENSG00000109787.82564.969901972.452000.378904.194002.85650K562SRSF4
KLF3ENSG00000109787.83461.144402573.301400.427504.525902.55640K562SRSF9
KLF3ENSG00000109787.82057.849501539.718800.418403.314102.19460K562SUPV3L1
KLF3ENSG00000109787.82000.668001636.176300.290102.098001.47590K562TARDBP
KLF3ENSG00000109787.81935.795801488.185500.379302.930501.96600K562TIAL1
KLF3ENSG00000109787.82253.500301580.840500.511402.312301.45900K562TRIM56
KLF3ENSG00000109787.83182.144902143.117000.570203.740701.65560K562TRNAU1AP
KLF3ENSG00000109787.81468.145001214.907300.273002.384701.63910K562U2AF2
KLF3ENSG00000109787.82329.585802823.30030-0.277304.358403.47620K562UPF1
KLF3ENSG00000109787.83622.208302512.088900.527909.853008.36540K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KLF3 is not available on ENCORE database.





4 RBPs can affect the splicing of KLF3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKLF3ENSG00000109787.8chr4+386895833868980738682207386823033869020538690692-0.131000.000080.00225excludedHepG2U2AF1
SEKLF3ENSG00000109787.8chr4+3868958338689807386822073868230338690205386906920.137000.000280.03334includedHepG2DDX59
SEKLF3ENSG00000109787.8chr4+3868958338689807386822073868230338690205386906920.193000.000020.00193includedHepG2SFPQ
SEKLF3ENSG00000109787.8chr4+3868958338689807386822073868230338690205386906920.129000.000050.08244includedHepG2NIP7

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KLF3 is not avaliable on ENCORE database.