PSMB3

General Information

Gene Name       : PSMB3
Gene ID             : ENSG00000277791.4
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PSMB3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PSMB3ENSG00000277791.4174.96240.06207.51ENCSR000AEF
HepG2PSMB3ENSG00000277791.4407.35328.32367.84ENCSR985KAT
K562PSMB3ENSG00000277791.4388.83392.51390.67ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PSMB3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PSMB3 RNA is bound by 13 proteins.  







eCLIP assay for PSMB3 is not avaliable on ENCORE database.





13 proteins are bound to PSMB3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr173691866236918743+3'-UTR,CDS,intron-Proximal3.8964611.11900K562APOBEC3C
chr173691866536918676+3'-UTR,CDS6.1866810.38505K562RPS3
chr173691681736916861+3'-UTR,CDS,intron-Distal4.048337.88650K562APOBEC3C
chr173691683736916861+3'-UTR,CDS,intron-Distal4.156345.69815HepG2G3BP1
chr173691869236918743+3'-UTR,CDS4.3286614.79781K562PABPC4
chr173691679736916820+3'-UTR,CDS,intron-Distal5.0149511.62844K562RPS3
chr173691866236918710+3'-UTR,CDS,intron-Proximal4.058076.74349HepG2DDX55
chr173691684636916858+3'-UTR,CDS,intron-Distal3.376914.22960K562SND1
chr173691675036916793+3'-UTR,CDS,intron-Distal,intron-Proximal5.252678.66806HepG2G3BP1
chr173691867536918733+3'-UTR,CDS5.4712710.62744HepG2RPS3
chr173692037336920410+3'-UTR,CDS3.690469.26008K562YBX3
chr173691679336916837+3'-UTR,CDS,intron-Distal3.667704.96885HepG2G3BP1
chr173691674036916812+3'-UTR,CDS,intron-Distal,intron-Proximal3.1836810.65714K562SND1
chr173691866336918728+3'-UTR,CDS,intron-Proximal4.711868.81535HepG2G3BP1
chr173691683336916861+3'-UTR,CDS,intron-Distal3.175305.17412K562PABPC4
chr173690940236909438+5'-UTR,CDS,intron-Proximal5.734645.40098K562GEMIN5
chr173690902936909084+5'-UTR,CDS,intron-Proximal4.4603341.90257K562DDX3X
chr173690940636909455+5'-UTR,CDS3.1892825.71670K562DDX3X
chr173690940236909448+5'-UTR,CDS,intron-Proximal5.8519331.01671HepG2SUB1
chr173690904336909082+5'-UTR,CDS,intron-Proximal4.964964.18952HepG2SUB1
chr173690903536909082+5'-UTR,CDS,intron-Proximal4.4777916.71931K562PABPC4
chr173690940536909458+5'-UTR,CDS3.618685.40978K562NOLC1
chr173690906936909076+5'-UTR,intron-Proximal3.432634.08506K562APOBEC3C
chr173690940236909406+5'-UTR,CDS,intron-Proximal3.6074510.44075K562DDX3X
chr173690952536909588+CDS,intron-Proximal4.7992926.74103HepG2RPS3
chr173691213436912164+CDS,intron-Proximal4.5698613.05138K562RPS3
chr173690940936909446+CDS4.084477.19148K562APOBEC3C
chr173690955036909573+CDS3.165068.74043K562YBX3
chr173691670536916728+CDS,intron-Distal,intron-Proximal3.7986017.44716K562YBX3
chr173691217036912218+CDS3.906383.77614HepG2G3BP1
chr173691670636916744+CDS,intron-Distal,intron-Proximal5.6572417.35258K562RPS3
chr173691213536912148+CDS,intron-Proximal3.307176.73537HepG2RPS3
chr173691674236916781+CDS,intron-Distal,intron-Proximal4.818175.48383HepG2LARP4
chr173690953536909585+CDS4.7087840.61840K562RPS3
chr173690941036909454+CDS3.403006.05703K562DDX55
chr173690952336909550+CDS3.1387210.55156K562YBX3
chr173691672836916756+CDS,intron-Distal,intron-Proximal3.0497613.84839K562YBX3
chr173691669236916704+CDS,intron-Distal,intron-Proximal3.8154012.47992K562YBX3
chr173690941236909458+CDS7.1866810.38650K562RPS3
chr173690910136909217+intron-Distal,intron-Proximal5.442347.81430K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PSMB3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PSMB3 is not available on ENCORE database.

  • 101 RBPs can affect the levels of PSMB3.  








The Knockdown/knockout RNA-Seq assay for PSMB3 is not available on ENCORE database.





101 RBPs can affect the gene expression of PSMB3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PSMB3ENSG00000108294.43895.514502351.850000.727908.393207.52240HepG2AKAP1
PSMB3ENSG00000108294.42219.763302805.20320-0.337705.472104.56270HepG2AUH
PSMB3ENSG00000108294.41155.083201537.65930-0.412703.285002.30590HepG2BCLAF1
PSMB3ENSG00000108294.4648.84950819.41170-0.336702.387501.66740HepG2CALR
PSMB3ENSG00000108294.42553.221101848.746000.465704.515503.54110HepG2CIRBP
PSMB3ENSG00000108294.4585.66830750.45160-0.357702.236601.60970HepG2CPSF6
PSMB3ENSG00000108294.4594.00790852.19520-0.520702.192201.32580HepG2DDX59
PSMB3ENSG00000108294.41229.878201449.89980-0.237402.341101.70980HepG2DKC1
PSMB3ENSG00000108294.41199.615001860.28500-0.633006.785105.88360HepG2EIF2S1
PSMB3ENSG00000108294.41410.746702521.05960-0.8376022.6436020.74910HepG2EIF4G1
PSMB3ENSG00000108294.41666.773902414.96630-0.534904.981403.90930HepG2EIF4G2
PSMB3ENSG00000108294.4727.30450983.85310-0.435903.503802.28110HepG2ESF1
PSMB3ENSG00000108294.42344.700203220.81470-0.4580010.422509.37670HepG2ETF1
PSMB3ENSG00000108294.42039.064001480.910300.461305.575204.38570HepG2EWSR1
PSMB3ENSG00000108294.41128.883601448.35520-0.359502.996701.67710HepG2FKBP4
PSMB3ENSG00000108294.4254.13190751.75250-1.564709.583907.72460HepG2FTO
PSMB3ENSG00000108294.4964.423401285.15090-0.414203.849202.93090HepG2FUBP3
PSMB3ENSG00000108294.41585.117502043.20060-0.366202.860301.95170HepG2G3BP2
PSMB3ENSG00000108294.41297.735401714.94180-0.402206.188205.17410HepG2HNRNPF
PSMB3ENSG00000108294.4561.28500811.81760-0.532404.040703.29450HepG2HNRNPLL
PSMB3ENSG00000108294.41214.704601444.54280-0.250002.560401.97710HepG2HNRNPU
PSMB3ENSG00000108294.41299.570701688.72690-0.377904.122003.25260HepG2IGF2BP1
PSMB3ENSG00000108294.41253.165101967.42440-0.650705.483204.02450HepG2KHSRP
PSMB3ENSG00000108294.4522.65430827.99060-0.663803.789802.64390HepG2MTPAP
PSMB3ENSG00000108294.4452.92250719.84560-0.668405.754104.69700HepG2NSUN2
PSMB3ENSG00000108294.41138.642801901.86740-0.740108.942207.66250HepG2PABPC4
PSMB3ENSG00000108294.41697.472901968.26310-0.213502.377401.80600HepG2PCBP1
PSMB3ENSG00000108294.41021.024201288.41390-0.335603.548902.72420HepG2PPIL4
PSMB3ENSG00000108294.41079.287301341.89350-0.314202.331901.58730HepG2PRPF8
PSMB3ENSG00000108294.41545.286802002.76110-0.374105.476404.76150HepG2PTBP1
PSMB3ENSG00000108294.41946.463402418.70520-0.313402.261101.71410HepG2PUF60
PSMB3ENSG00000108294.41328.586402169.08290-0.7072014.7516013.47170HepG2QKI
PSMB3ENSG00000108294.43378.141002691.991300.327504.920604.27950HepG2RBM22
PSMB3ENSG00000108294.41342.029801968.56580-0.552707.723706.64660HepG2RBM25
PSMB3ENSG00000108294.41803.935602228.89770-0.305204.266503.62070HepG2NELFE
PSMB3ENSG00000108294.41410.488402075.88480-0.5575012.0756010.92490HepG2RECQL
PSMB3ENSG00000108294.41392.729801847.43070-0.407603.745102.96950HepG2RPLP0
PSMB3ENSG00000108294.41090.831501286.41940-0.237902.479501.86350HepG2SAFB2
PSMB3ENSG00000108294.41619.926001117.332400.535801.920901.35640HepG2SF3A3
PSMB3ENSG00000108294.4626.93940803.52790-0.358002.314801.66650HepG2SF3B1
PSMB3ENSG00000108294.41673.575102085.16910-0.317204.547303.81750HepG2SF3B4
PSMB3ENSG00000108294.41718.957302319.36530-0.432204.873903.98310HepG2SLBP
PSMB3ENSG00000108294.41969.282902388.23820-0.278303.472102.78530HepG2SRSF5
PSMB3ENSG00000108294.41289.673601684.87790-0.385605.901304.94730HepG2SRSF7
PSMB3ENSG00000108294.41254.625601770.64550-0.4970010.037109.10040HepG2SRSF9
PSMB3ENSG00000108294.41821.226802639.81470-0.5355013.4003012.44070HepG2SSB
PSMB3ENSG00000108294.4543.94930774.34770-0.509504.634503.43420HepG2SUPT6H
PSMB3ENSG00000108294.41292.197501732.21040-0.422803.639202.87990HepG2SUPV3L1
PSMB3ENSG00000108294.41155.814601956.23730-0.7592017.4668016.23250HepG2TAF15
PSMB3ENSG00000108294.4461.32360791.32190-0.778508.245907.08280HepG2TARDBP
PSMB3ENSG00000108294.41400.104801797.55920-0.360503.853102.87450HepG2TIA1
PSMB3ENSG00000108294.41080.517901416.19490-0.390305.540004.79380HepG2TRIM56
PSMB3ENSG00000108294.41397.98250956.679000.547109.707808.69600HepG2UTP3
PSMB3ENSG00000108294.4886.435401237.56000-0.481402.674201.43990HepG2XRCC5
PSMB3ENSG00000108294.4845.084201070.47130-0.341104.102303.30900HepG2ZC3H8
PSMB3ENSG00000108294.42035.642901089.804200.9013036.1552034.75900HepG2ZNF622
PSMB3ENSG00000108294.4903.150401257.36780-0.477402.917601.58130HepG2ZRANB2
PSMB3ENSG00000108294.42814.239301779.480700.6612019.5085018.11780K562AGGF1
PSMB3ENSG00000108294.42671.586801955.467900.450102.933401.91220K562AKAP8
PSMB3ENSG00000108294.42806.796501851.651900.600009.018107.76160K562AKAP8L
PSMB3ENSG00000108294.43216.453704056.81420-0.334903.137502.51980K562AQR
PSMB3ENSG00000108294.41996.800402514.58880-0.332605.439604.07670K562BCLAF1
PSMB3ENSG00000108294.4645.54020890.58490-0.464203.397302.43020K562BOP1
PSMB3ENSG00000108294.4689.351101173.54160-0.767609.785207.45700K562CCAR1
PSMB3ENSG00000108294.42852.514102224.440100.358702.622701.37980K562CIRBP
PSMB3ENSG00000108294.4706.90770946.97550-0.421803.777202.86120K562CPSF6
PSMB3ENSG00000108294.41551.452601907.69010-0.298202.981701.88290K562CSTF2
PSMB3ENSG00000108294.44093.283604877.90850-0.253003.087902.05850K562CELF1
PSMB3ENSG00000108294.41799.808502142.55690-0.251502.789801.57330K562DDX21
PSMB3ENSG00000108294.4891.247501313.68960-0.559705.545903.53630K562DHX30
PSMB3ENSG00000108294.42602.526301992.375000.385306.301204.89480K562DKC1
PSMB3ENSG00000108294.4828.210601261.99020-0.607606.435604.41410K562DNAJC21
PSMB3ENSG00000108294.4661.950001193.73060-0.850706.256304.69800K562EIF3A
PSMB3ENSG00000108294.43260.771503966.59630-0.282704.240503.08560K562EIF4G2
PSMB3ENSG00000108294.4987.672101414.09440-0.517803.391601.55190K562ESF1
PSMB3ENSG00000108294.42058.025101641.776200.325903.491702.01010K562EWSR1
PSMB3ENSG00000108294.41276.175901861.37720-0.544503.856102.32130K562EXOSC5
PSMB3ENSG00000108294.41146.604001530.05900-0.416204.589302.47360K562FASTKD2
PSMB3ENSG00000108294.41831.044501329.774000.461404.078403.03550K562FIP1L1
PSMB3ENSG00000108294.41203.214701625.97910-0.434403.506602.21740K562FKBP4
PSMB3ENSG00000108294.4662.26830963.47050-0.540804.741803.61960K562FMR1
PSMB3ENSG00000108294.4497.04100816.60440-0.716306.545305.07920K562FTO
PSMB3ENSG00000108294.42771.042901955.998400.5024010.037908.96960K562FXR1
PSMB3ENSG00000108294.4632.661801393.36240-1.1391013.9656012.10400K562G3BP2
PSMB3ENSG00000108294.42386.256803179.14830-0.413905.366303.88760K562HNRNPA1
PSMB3ENSG00000108294.41102.579801872.17840-0.7638013.1894011.96630K562HNRNPC
PSMB3ENSG00000108294.41758.478301093.869700.684802.738301.81350K562HNRNPM
PSMB3ENSG00000108294.42392.118103520.81050-0.5576011.621309.81540K562HNRNPU
PSMB3ENSG00000108294.42167.804301802.734600.265901.991801.31140K562HSPD1
PSMB3ENSG00000108294.42666.680702076.516100.360802.233101.34000K562IGF2BP2
PSMB3ENSG00000108294.4822.111001185.03560-0.527504.818302.86620K562KHDRBS1
PSMB3ENSG00000108294.42524.697501964.990000.361503.736102.75800K562KIF1C
PSMB3ENSG00000108294.4491.23760771.97310-0.652104.399403.19510K562KRR1
PSMB3ENSG00000108294.42817.666602181.296700.369204.033803.01310K562MAGOH
PSMB3ENSG00000108294.42390.935201881.040200.345902.688701.63130K562MAK16
PSMB3ENSG00000108294.42623.478502201.295600.253002.319801.49920K562MBNL1
PSMB3ENSG00000108294.41519.476301867.25110-0.297304.077803.11230K562MTPAP
PSMB3ENSG00000108294.42148.743201542.955500.477703.452302.44400K562NAA15
PSMB3ENSG00000108294.41594.517602074.65000-0.379708.224407.03550K562NSUN2
PSMB3ENSG00000108294.41700.937902367.67220-0.477104.272203.23750K562PCBP3
PSMB3ENSG00000108294.42348.212701509.717500.637208.698607.04440K562PPIG
PSMB3ENSG00000108294.41025.761001486.00400-0.534703.304101.33650K562PPIL4
PSMB3ENSG00000108294.42892.054002070.417300.482105.077604.06330K562PRPF8
PSMB3ENSG00000108294.42922.993002119.344100.463706.500305.51640K562PTBP1
PSMB3ENSG00000108294.43927.330604603.89320-0.229302.571501.54420K562PUM1
PSMB3ENSG00000108294.43667.351604510.25620-0.298504.796903.52130K562PUM2
PSMB3ENSG00000108294.43521.237701836.176700.9393018.8852017.50010K562PUS1
PSMB3ENSG00000108294.42653.799201789.205100.5686011.4072010.22130K562RBM15
PSMB3ENSG00000108294.42108.257501143.371900.882704.150402.59540K562SF1
PSMB3ENSG00000108294.41757.016902047.20020-0.220502.060501.34930K562SF3A3
PSMB3ENSG00000108294.41869.264101448.751600.367604.108503.06040K562SF3B4
PSMB3ENSG00000108294.4904.285501292.69950-0.515503.817502.31220K562SLBP
PSMB3ENSG00000108294.42573.453902077.780600.308602.155301.52280K562SRSF1
PSMB3ENSG00000108294.41541.840302067.32870-0.423104.579602.59350K562SRSF9
PSMB3ENSG00000108294.41167.891401475.23590-0.337003.970502.39560K562SSB
PSMB3ENSG00000108294.41519.211502004.07970-0.399603.132602.05010K562SUPV3L1
PSMB3ENSG00000108294.41120.144501614.55400-0.527504.917703.63880K562TIAL1
PSMB3ENSG00000108294.41318.773701715.50540-0.379403.589402.48590K562TRIM56
PSMB3ENSG00000108294.41265.396701721.32520-0.443903.753401.66170K562TRNAU1AP
PSMB3ENSG00000108294.41581.456302121.33760-0.423704.009502.76090K562UCHL5
PSMB3ENSG00000108294.41611.699602199.79800-0.448808.789107.59660K562UPF1
PSMB3ENSG00000108294.41399.320901882.29340-0.427804.947503.76090K562WDR3
PSMB3ENSG00000108294.41573.516701957.39660-0.314904.860603.76730K562WDR43
PSMB3ENSG00000108294.41604.448202160.53440-0.429304.048502.47680K562XRN2
PSMB3ENSG00000108294.43126.218204570.46690-0.547908.205806.59290K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PSMB3 is not available on ENCORE database.





10 RBPs can affect the splicing of PSMB3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPSMB3ENSG00000108294.4chr17+369166833691686136912135369122433691866336918758-0.090000.000000.00000excludedK562SRSF1
SEPSMB3ENSG00000108294.4chr17+369166833691686136912135369122433691866336918758-0.194000.000000.00000excludedK562PRPF8
SEPSMB3ENSG00000108294.4chr17+369166833691682436912135369122433691866336918758-0.055000.000000.00007excludedK562AQR
SEPSMB3ENSG00000108294.4chr17+369166833691686136912135369122433691866336918758-0.155000.000000.00000excludedK562EFTUD2
SEPSMB3ENSG00000108294.4chr17+369166833691686136912135369122433691866336918758-0.051000.000020.00104excludedHepG2SF3A3
SEPSMB3ENSG00000108294.4chr17+369166833691682436912135369122433691866336918758-0.062000.000350.03091excludedHepG2TIAL1
SEPSMB3ENSG00000108294.4chr17+369166833691682436912135369122433691866336918758-0.054000.000760.08546excludedK562RBM22
SEPSMB3ENSG00000108294.4chr17+369166833691686136912135369122433691866336918758-0.065000.000000.00000excludedK562TARDBP
SEPSMB3ENSG00000108294.4chr17+369166833691686136912135369122433691866336918758-0.066000.000000.00000excludedK562HNRNPU
SEPSMB3ENSG00000108294.4chr17+369166833691682436912135369122433691866336918758-0.051000.000990.04255excludedHepG2HNRNPU
SEPSMB3ENSG00000108294.4chr17+369166833691682436912135369122433691866336918758-0.053000.000830.03328excludedHepG2HNRNPC
SEPSMB3ENSG00000108294.4chr17+369166833691686136912135369122433691866336918758-0.162000.000000.00000excludedK562HNRNPC
A3SSPSMB3ENSG00000108294.4chr17+3691856736918758369186633691875836912135369122430.077000.000380.00291longerK562AQR
RIPSMB3ENSG00000108294.4chr17+3691830336918758369183033691855036918663369187580.059000.009850.05314includedK562AQR
MXEPSMB3ENSG00000108294.4chr17+36912135369122433691668336916861369094023690958736918663369187580.137000.000000.000221includedK562EFTUD2
MXEPSMB3ENSG00000108294.4chr17+36912135369122433691668336916861369094023690958736918663369187580.105000.000420.010241includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PSMB3 is not avaliable on ENCORE database.