NUMBL

General Information

Gene Name       : NUMBL
Gene ID             : ENSG00000105245.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NUMBL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NUMBLENSG00000105245.90.901.171.03ENCSR000AEF
HepG2NUMBLENSG00000105245.92.230.531.38ENCSR985KAT
K562NUMBLENSG00000105245.99.926.067.99ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NUMBL is not avaliable on ENCORE database.



Proteins bound to RNA
  • NUMBL RNA is bound by 19 proteins.  







eCLIP assay for NUMBL is not avaliable on ENCORE database.





19 proteins are bound to NUMBL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194117288641172990-3'-UTR,intron-Distal,intron-Proximal4.275613.02541K562IGF2BP2
chr194119043041190516-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.604398.71620K562SF3B4
chr194119677841196834-5'-UTR,intron-Distal4.4693010.86370HepG2CSTF2T
chr194119653541196627-5'-UTR,intron-Distal,intron-Proximal3.956435.16644HepG2FAM120A
chr194119650041196631-5'-UTR,intron-Distal,intron-Proximal5.3035817.55294HepG2CSTF2T
chr194119601941196055-5'-UTR,intron-Distal,intron-Proximal4.569764.61649HepG2CSTF2T
chr194119580241195968-5'-UTR,intron-Distal5.6713336.93544K562EIF4G2
chr194119626041196366-5'-UTR,CDS,intron-Distal3.345436.65588K562AQR
chr194117916741179260-CDS,intron-Distal,intron-Proximal5.077076.44303K562AQR
chr194118865541188765-CDS,intron-Distal,intron-Proximal4.126815.85871K562EFTUD2
chr194119024141190324-CDS,intron-Distal,intron-Proximal4.251807.30031K562AQR
chr194117590641175987-CDS,intron-Distal,intron-Proximal5.050935.90023K562SF3B4
chr194117581141175858-CDS,intron-Distal3.634623.01531K562YBX3
chr194119471141194784-intron-Distal5.3672123.62362K562TARDBP
chr194119620341196318-intron-Distal3.976527.15757HepG2NKRF
chr194119533241195385-intron-Distal5.8896115.75178K562TARDBP
chr194119120141191272-intron-Distal4.7142433.50703K562AGGF1
chr194119179441191874-intron-Distal4.2771211.48957K562HNRNPL
chr194119499641195079-intron-Distal6.5658727.35793K562TARDBP
chr194119478441194840-intron-Distal6.2378422.18212K562TARDBP
chr194119371141193787-intron-Distal7.1794025.93204K562EIF4G2
chr194119138141191448-intron-Distal4.371959.36782K562HNRNPL
chr194119115341191201-intron-Distal5.8241039.53403K562AGGF1
chr194119355041193606-intron-Distal7.3317434.47819K562EIF4G2
chr194119144841191519-intron-Distal5.057346.76480K562HNRNPL
chr194119419441194231-intron-Distal7.0074324.92890K562EIF4G2
chr194119106541191137-intron-Distal5.4659013.27457K562HNRNPL
chr194119502641195103-intron-Distal6.2971944.69331K562EIF4G2
chr194119620041196275-intron-Distal5.5500813.30116HepG2CSTF2T
chr194119619841196261-intron-Distal5.253778.86792K562CSTF2T
chr194119081541190977-intron-Distal,intron-Proximal3.785385.90869K562EIF4G2
chr194119543141195468-intron-Distal5.9865813.20892K562EIF4G2
chr194119340341193461-intron-Distal7.0708430.45263K562EIF4G2
chr194119622441196342-intron-Distal4.406325.97891K562FAM120A
chr194119373641193793-intron-Distal5.6620628.29926K562TARDBP
chr194119361941193669-intron-Distal5.6199512.68695K562TARDBP
chr194119618441196298-intron-Distal3.707823.15856K562FUS
chr194119526341195332-intron-Distal4.9209824.87528K562TARDBP
chr194119129541191334-intron-Distal3.595515.12846K562HNRNPL
chr194119626141196312-intron-Distal3.121455.12258K562CSTF2T
chr194119621041196255-intron-Distal4.858967.22168HepG2FAM120A
chr194119498341195033-intron-Distal4.330323.96304K562CSTF2T
chr194119146241191501-intron-Distal4.8116217.19718K562AGGF1
chr194119420541194255-intron-Distal4.8049714.53709K562TARDBP
chr194119324941193302-intron-Distal4.2998014.57061K562TARDBP
chr194119436341194420-intron-Distal7.2680531.45845K562EIF4G2
chr194119619641196255-intron-Distal5.3779624.96029K562EIF4G2
chr194119174641191820-intron-Distal5.8307640.38831K562AGGF1
chr194119187441191935-intron-Distal3.204205.22824K562HNRNPL
chr194119118041191274-intron-Distal4.9218023.94875K562HNRNPL
chr194119551841195549-intron-Distal,intron-Proximal3.851863.59342K562CSTF2T
chr194119436741194492-intron-Distal5.9521634.39874K562TARDBP
chr194119458841194599-intron-Distal4.866936.48464K562TARDBP
chr194119080641190879-intron-Distal,intron-Proximal3.746583.11802K562HNRNPK
chr194119196041192006-intron-Distal4.171213.19026HepG2HNRNPL
chr194119461041194638-intron-Distal5.8444110.98400K562EIF4G2
chr194119559441195705-intron-Distal,intron-Proximal6.1917442.21276K562EIF4G2
chr194119405741194079-intron-Distal6.7944123.56345K562EIF4G2
chr194119405841194120-intron-Distal5.091478.31268K562CSTF2T
chr194119255541192628-intron-Distal5.3672010.67463K562HNRNPL
chr194119255641192643-intron-Distal3.8523914.94773K562AGGF1
chr194119390841193945-intron-Distal3.681338.85527K562TARDBP
chr194119326941193304-intron-Distal4.324574.01524K562FAM120A
chr194119626341196330-intron-Distal5.9021423.65460K562EIF4G2
chr194119560541195691-intron-Distal5.3847810.34825HepG2CSTF2T
chr194119435141194423-intron-Distal5.171529.97545K562CSTF2T
chr194119360641193667-intron-Distal7.8019648.60367K562EIF4G2
chr194119534741195381-intron-Distal6.0950513.45380K562EIF4G2
chr194119375941193794-intron-Distal3.893093.43867K562CSTF2T
chr194119153941191598-intron-Distal5.256019.08942K562HNRNPL
chr194119585141195940-intron-Distal3.944646.60399K562CSTF2T
chr194119356841193658-intron-Distal3.953217.33288K562NONO
chr194119550941195555-intron-Distal,intron-Proximal5.3292215.32107K562EIF4G2
chr194119499141195019-intron-Distal6.1253514.44525K562EIF4G2
chr194119451841194568-intron-Distal5.9073217.27478K562TARDBP
chr194119118341191265-intron-Distal4.065355.29549HepG2HNRNPL
chr194119242341192528-intron-Distal4.639418.89873K562HNRNPL
chr194119580641195928-intron-Distal5.526589.35257HepG2CSTF2T
chr194119442341194476-intron-Distal4.520623.20137K562DDX52
chr194119404441194098-intron-Distal4.009263.28464K562EWSR1
chr194119523141195263-intron-Distal4.9049014.78429K562TARDBP
chr194119334841193407-intron-Distal6.0613118.65589K562TARDBP
chr194119406241194117-intron-Distal3.906325.10007K562FAM120A
chr194119484041194893-intron-Distal5.8485316.73742K562TARDBP
chr194119315341193195-intron-Distal4.909424.41467K562DDX52
chr194119461741194638-intron-Distal4.810267.67146K562TARDBP
chr194119355241193647-intron-Distal5.3402710.80335K562CSTF2T
chr194119407341194176-intron-Distal6.5587728.34209K562TARDBP
chr194119312141193191-intron-Distal6.5232737.05993K562EIF4G2
chr194119311841193187-intron-Distal4.772517.00800K562CSTF2T
chr194119380041193876-intron-Distal6.3667124.22342K562TARDBP
chr194119325741193304-intron-Distal3.224573.25653K562CSTF2T
chr194119340141193459-intron-Distal4.636045.01722K562CSTF2T
chr194119550441195563-intron-Distal,intron-Proximal3.721596.26465HepG2CSTF2T
chr194119322841193249-intron-Distal3.319945.95210K562TARDBP
chr194119627541196349-intron-Distal5.3569510.82255HepG2CSTF2T
chr194119356741193647-intron-Distal4.155903.06537K562RBFOX2
chr194119321641193257-intron-Distal3.263573.50009K562CSTF2T
chr194119466941194711-intron-Distal5.5758913.70780K562TARDBP
chr194119563541195687-intron-Distal4.636044.46951K562FAM120A
chr194119175541191839-intron-Distal4.904114.77636HepG2HNRNPL
chr194119423141194250-intron-Distal6.5741219.92343K562EIF4G2
chr194119164241191701-intron-Distal3.998387.75636K562HNRNPL
chr194119302841193075-intron-Distal4.438394.48935K562CSTF2T
chr194119535041195381-intron-Distal4.029603.96304K562CSTF2T
chr194119618741196283-intron-Distal4.626495.63746K562EWSR1
chr194119319641193250-intron-Distal5.5081114.83536K562EIF4G2
chr194119407941194107-intron-Distal5.9844626.98721K562EIF4G2
chr194119117641191249-intron-Distal3.698933.41960K562GTF2F1
chr194119619141196332-intron-Distal4.3416312.80035K562GTF2F1
chr194119195341192022-intron-Distal5.5209910.67463K562HNRNPL
chr194119369641193736-intron-Distal6.3297122.99716K562TARDBP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NUMBL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NUMBL is not available on ENCORE database.

  • 86 RBPs can affect the levels of NUMBL.  








The Knockdown/knockout RNA-Seq assay for NUMBL is not available on ENCORE database.





86 RBPs can affect the gene expression of NUMBL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NUMBLENSG00000105245.5207.1859075.119701.4636012.1872011.10340HepG2ACO1
NUMBLENSG00000105245.592.4733031.464801.555204.567203.90610HepG2AKAP1
NUMBLENSG00000105245.5156.9827091.844300.773202.794001.75240HepG2AKAP8
NUMBLENSG00000105245.5187.8999051.250901.874207.524905.94020HepG2BCCIP
NUMBLENSG00000105245.5252.22420133.857500.913904.517503.25750HepG2CCAR1
NUMBLENSG00000105245.536.1636075.10540-1.054403.161502.46090HepG2CKAP4
NUMBLENSG00000105245.556.28770139.75970-1.312105.827904.86320HepG2CPSF6
NUMBLENSG00000105245.5259.7370054.718702.2468026.9099025.33130HepG2CELF1
NUMBLENSG00000105245.571.4141030.143101.244303.065402.41230HepG2DDX3X
NUMBLENSG00000105245.567.14620158.70830-1.241004.701803.43720HepG2DDX59
NUMBLENSG00000105245.574.0078025.888501.515304.091903.35200HepG2DDX6
NUMBLENSG00000105245.5161.9200072.908601.151005.493203.87970HepG2EIF2S2
NUMBLENSG00000105245.586.7367026.781501.695304.910204.01070HepG2EIF4B
NUMBLENSG00000105245.5225.6793089.782701.329709.714708.69860HepG2ETF1
NUMBLENSG00000105245.5181.7470097.067800.904803.216202.39270HepG2FIP1L1
NUMBLENSG00000105245.580.2755027.750401.532404.634503.75540HepG2FXR1
NUMBLENSG00000105245.570.8277025.746401.459804.103503.30230HepG2G3BP1
NUMBLENSG00000105245.5126.5191033.708001.908108.546906.75700HepG2GNB2L1
NUMBLENSG00000105245.5226.41320158.420400.515101.830701.30270HepG2GPKOW
NUMBLENSG00000105245.5106.9148053.600000.996103.753202.97610HepG2HNRNPL
NUMBLENSG00000105245.514.7511055.34060-1.907505.506704.67350HepG2HNRNPU
NUMBLENSG00000105245.597.4486034.668701.490904.922003.29390HepG2LIN28B
NUMBLENSG00000105245.5120.3782027.916602.108309.220108.12290HepG2MATR3
NUMBLENSG00000105245.5145.4704058.345501.317902.954302.16640HepG2NOL12
NUMBLENSG00000105245.580.31220134.05960-0.739202.382601.68670HepG2NSUN2
NUMBLENSG00000105245.551.8037025.452501.025101.945301.33100HepG2PABPC4
NUMBLENSG00000105245.5146.8789032.686702.1678015.0062013.77500HepG2PCBP1
NUMBLENSG00000105245.5144.9704033.260202.1238013.8257012.78680HepG2PTBP1
NUMBLENSG00000105245.5189.6574075.039301.337608.402707.61400HepG2RBM22
NUMBLENSG00000105245.572.6511032.691601.152003.055802.35090HepG2RBM25
NUMBLENSG00000105245.588.7220039.845301.154802.926801.90470HepG2RBM27
NUMBLENSG00000105245.578.3771037.015201.082202.853602.30600HepG2NELFE
NUMBLENSG00000105245.564.5754034.475000.905301.847601.32940HepG2RECQL
NUMBLENSG00000105245.5124.7227039.388301.662807.740706.77390HepG2RPS19
NUMBLENSG00000105245.579.12960149.63780-0.919203.671402.86820HepG2SF3B1
NUMBLENSG00000105245.565.1931034.627700.912701.922601.41460HepG2SF3B4
NUMBLENSG00000105245.5104.3159040.156901.377105.506204.12310HepG2SMNDC1
NUMBLENSG00000105245.5334.45760166.500001.006205.326604.23190HepG2SNRNP70
NUMBLENSG00000105245.572.3509036.144001.001202.423601.97340HepG2SRSF1
NUMBLENSG00000105245.5220.8979054.988902.0061019.8268018.35700HepG2SRSF5
NUMBLENSG00000105245.5120.4440029.405202.0341012.2635011.24770HepG2SRSF9
NUMBLENSG00000105245.5314.03290147.379201.091308.201207.04030HepG2TARDBP
NUMBLENSG00000105245.5119.6563053.776701.153704.988504.35780HepG2TIAL1
NUMBLENSG00000105245.5155.4795054.254201.5188010.183909.20660HepG2TRIM56
NUMBLENSG00000105245.5115.1184054.409301.081103.964502.89610HepG2TUFM
NUMBLENSG00000105245.5128.7013048.619401.404302.991801.96180HepG2U2AF2
NUMBLENSG00000105245.5420.70500289.943800.536903.680802.12180K562BCCIP
NUMBLENSG00000105245.5442.64620280.210200.659505.839104.42830K562BCLAF1
NUMBLENSG00000105245.5786.56360569.774300.465103.120301.59250K562BUD13
NUMBLENSG00000105245.5670.74390396.812500.757204.871503.38120K562CCAR1
NUMBLENSG00000105245.51259.92500782.962100.686204.021402.23040K562CKAP4
NUMBLENSG00000105245.5964.93460672.070200.521702.421701.43930K562CNOT7
NUMBLENSG00000105245.5343.96200212.581200.694102.578501.56340K562CSTF2
NUMBLENSG00000105245.5879.06120656.433600.421204.224502.70870K562DDX21
NUMBLENSG00000105245.5401.58690209.535200.938407.154105.37650K562DDX3X
NUMBLENSG00000105245.51318.40440861.292400.614107.643206.63360K562DDX47
NUMBLENSG00000105245.5752.24140444.295300.759604.691202.87220K562DHX30
NUMBLENSG00000105245.5372.23440267.125500.478602.220801.40280K562EFTUD2
NUMBLENSG00000105245.5332.79080230.156900.531903.709202.29060K562EIF2S1
NUMBLENSG00000105245.5859.57140403.600901.090608.906007.06690K562EIF3A
NUMBLENSG00000105245.5214.2370099.972001.099507.348406.06320K562EIF3G
NUMBLENSG00000105245.5339.23190197.143000.782906.840404.89850K562EIF4B
NUMBLENSG00000105245.5791.89790588.023400.429303.206702.29080K562FIP1L1
NUMBLENSG00000105245.5862.01180594.223800.536604.180603.03740K562FTO
NUMBLENSG00000105245.5378.56280227.660100.733606.128505.28040K562FXR1
NUMBLENSG00000105245.522.6580084.26810-1.895006.683405.48020K562G3BP2
NUMBLENSG00000105245.5950.93850705.250400.431104.459203.01460K562GLRX3
NUMBLENSG00000105245.5944.25590657.930600.521104.784803.74390K562GPKOW
NUMBLENSG00000105245.5636.51190351.132900.858109.351608.30550K562HNRNPC
NUMBLENSG00000105245.5549.95180313.599300.810307.802805.80300K562HNRNPF
NUMBLENSG00000105245.5576.64490797.19100-0.467203.462002.57380K562HSPD1
NUMBLENSG00000105245.5334.48360144.974701.206004.566503.11420K562IGF2BP2
NUMBLENSG00000105245.5398.92850537.71330-0.430702.308101.56320K562KIF1C
NUMBLENSG00000105245.5763.86030561.747000.443302.346701.49560K562KRR1
NUMBLENSG00000105245.5667.89990356.207600.906805.447003.25400K562LIN28B
NUMBLENSG00000105245.5239.30470152.218800.652602.107101.36880K562MAGOH
NUMBLENSG00000105245.5331.77490151.888201.1271010.903508.96290K562MATR3
NUMBLENSG00000105245.51172.57890823.888000.509109.017007.77430K562NSUN2
NUMBLENSG00000105245.51016.25050645.665000.654303.854402.37490K562PABPC1
NUMBLENSG00000105245.5856.67910667.568200.359702.460101.68980K562PPIG
NUMBLENSG00000105245.5448.70760147.900901.6010020.8884019.13750K562PTBP1
NUMBLENSG00000105245.5619.65380851.32650-0.458302.932702.09250K562PUF60
NUMBLENSG00000105245.5307.80300141.740701.118709.288707.60220K562RBM22
NUMBLENSG00000105245.5235.63810138.230300.769404.129802.32190K562RBM34
NUMBLENSG00000105245.5495.96580287.298400.787604.100902.89120K562RCC2
NUMBLENSG00000105245.5280.01690149.177800.908404.238902.85330K562NELFE
NUMBLENSG00000105245.5426.33490264.713300.687503.834202.86960K562RPS19
NUMBLENSG00000105245.5462.06220260.448700.827005.673404.17270K562RPS3
NUMBLENSG00000105245.5968.70430612.227000.661903.249301.58300K562SBDS
NUMBLENSG00000105245.5916.04360625.654600.549904.004202.82190K562SF3B1
NUMBLENSG00000105245.5224.6603087.578801.3590011.287109.48990K562SF3B4
NUMBLENSG00000105245.5523.91410272.346100.943809.285007.08250K562SRFBP1
NUMBLENSG00000105245.51110.48090832.822900.415004.972503.76130K562SRPK2
NUMBLENSG00000105245.5343.77650145.008301.245206.322205.26380K562SRSF1
NUMBLENSG00000105245.5438.97700251.364500.804304.127202.80690K562SRSF4
NUMBLENSG00000105245.5571.90410771.47780-0.431902.901101.50460K562SSRP1
NUMBLENSG00000105245.5970.78610742.788500.386103.390301.73100K562SUCLG1
NUMBLENSG00000105245.5378.70810251.556800.590102.431701.48360K562SUPV3L1
NUMBLENSG00000105245.5436.43850146.723101.572608.289306.97820K562TARDBP
NUMBLENSG00000105245.5238.74540141.540100.754202.832502.00320K562TIA1
NUMBLENSG00000105245.5446.94250302.815300.561603.268802.24610K562TIAL1
NUMBLENSG00000105245.5210.16880138.975300.596602.539101.50200K562TRA2A
NUMBLENSG00000105245.5639.39980321.757600.9906011.707009.46850K562TRIM56
NUMBLENSG00000105245.5959.94380637.339500.590803.990801.84400K562TRNAU1AP
NUMBLENSG00000105245.5216.8611084.325101.3626010.676209.09300K562U2AF2
NUMBLENSG00000105245.5392.56220266.305600.559702.966601.90470K562UCHL5
NUMBLENSG00000105245.5408.64170271.274200.591003.281801.92830K562XRN2
NUMBLENSG00000105245.5827.94500656.419000.334802.274801.50410K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NUMBL is not available on ENCORE database.






No RBPs affect the alternative splcing events of NUMBL on ENCORE database.





The Knockdown/knockout RNA-Seq assay for NUMBL is not avaliable on ENCORE database.