MAD2L2

General Information

Gene Name       : MAD2L2
Gene ID             : ENSG00000116670.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MAD2L2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAD2L2ENSG00000116670.1413.5729.0021.29ENCSR000AEF
HepG2MAD2L2ENSG00000116670.1457.9236.6147.27ENCSR985KAT
K562MAD2L2ENSG00000116670.14133.38126.82130.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAD2L2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAD2L2 RNA is bound by 19 proteins.  







eCLIP assay for MAD2L2 is not avaliable on ENCORE database.





19 proteins are bound to MAD2L2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11174109411741138-3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.8049716.75565K562DDX3X
chr11174064011740671-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.319406.92152K562PABPC4
chr11173477711734802-3'-UTR,intron-Distal,intron-Proximal4.5583616.81236K562PABPC4
chr11174065111740694-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.560864.09264K562AQR
chr11174102911741177-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.122384.69669K562FTO
chr11173474511734777-3'-UTR,intron-Distal,intron-Proximal4.8484120.54725K562PABPC4
chr11173480211734844-3'-UTR,CDS,intron-Distal,intron-Proximal3.185927.02688K562PABPC4
chr11173457811734644-3'-UTR,intron-Distal,intron-Proximal3.891946.95607K562IGF2BP2
chr11173465211734740-3'-UTR,intron-Distal,intron-Proximal3.297506.45752K562DDX6
chr11173463711734729-3'-UTR,intron-Distal,intron-Proximal4.7324552.92930K562PABPC4
chr11173467011734750-3'-UTR,intron-Distal,intron-Proximal3.476607.55422K562METAP2
chr11173478611734874-3'-UTR,CDS,intron-Distal,intron-Proximal4.823825.50941K562PUM1
chr11173458311734637-3'-UTR,intron-Distal,intron-Proximal5.4829946.04564K562PABPC4
chr11173459011734628-3'-UTR,intron-Distal3.257614.30677K562YBX3
chr11173463611734735-3'-UTR,intron-Distal,intron-Proximal3.221138.01683HepG2LARP4
chr11173458811734758-3'-UTR,intron-Distal,intron-Proximal4.380008.75386HepG2AKAP1
chr11173459011734636-3'-UTR,intron-Distal,intron-Proximal4.143544.01795HepG2LARP4
chr11173459911734738-3'-UTR,intron-Distal,intron-Proximal5.5504312.58146HepG2UPF1
chr11174110511741181-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.267255.99204K562DDX55
chr11173473811734797-3'-UTR,intron-Distal,intron-Proximal3.588453.81620HepG2LARP4
chr11174113811741154-3'-UTR,5'-UTR,intron-Distal3.819307.12525K562DDX3X
chr11174109511741140-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.858258.40205K562PABPC4
chr11174109111741194-3'-UTR,5'-UTR,intron-Distal,intron-Proximal6.0881630.77170HepG2DDX3X
chr11174063411740671-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.1823010.24124K562DDX3X
chr11174098211741096-5'-UTR,intron-Distal,intron-Proximal4.9966010.60410K562AQR
chr11174095411741071-5'-UTR,intron-Distal,intron-Proximal3.324884.39249K562RBFOX2
chr11174061811740636-CDS,intron-Distal,intron-Proximal3.601815.55970K562YBX3
chr11173759311737601-CDS,intron-Distal,intron-Proximal4.1968110.08968K562AQR
chr11174045911740477-CDS,intron-Distal3.048426.03429K562LIN28B
chr11173518111735232-CDS,intron-Distal,intron-Proximal3.322457.51794K562YBX3
chr11174043311740527-CDS,intron-Distal,intron-Proximal3.191966.16065K562PABPC4
chr11174051511740530-CDS,intron-Distal,intron-Proximal3.337265.19705K562LIN28B
chr11174047711740515-CDS,intron-Distal4.0091812.17013K562LIN28B
chr11174045211740525-CDS,intron-Distal,intron-Proximal6.3511912.70669HepG2DDX3X
chr11173697811737049-CDS,intron-Distal,intron-Proximal4.604399.04180K562SF3B4
chr11173571411735739-CDS,intron-Distal,intron-Proximal3.066513.36125K562YBX3
chr11173752711737572-intron-Distal,intron-Proximal6.3966514.81397K562AQR
chr11173602111736063-intron-Distal,intron-Proximal4.767205.70555K562PRPF8
chr11173602311736069-intron-Distal,intron-Proximal4.481965.79396K562DDX24
chr11173757211737593-intron-Distal,intron-Proximal5.2380411.65116K562AQR
chr11173602911736072-intron-Distal,intron-Proximal4.012855.47926K562AQR
chr11173701111737042-intron-Distal,intron-Proximal4.324934.22101K562PRPF8
chr11173601211736063-intron-Distal,intron-Proximal3.415933.13705K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAD2L2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAD2L2 is not available on ENCORE database.

  • 94 RBPs can affect the levels of MAD2L2.  








The Knockdown/knockout RNA-Seq assay for MAD2L2 is not available on ENCORE database.





94 RBPs can affect the gene expression of MAD2L2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAD2L2ENSG00000116670.10277.42690541.38200-0.964508.897707.54280HepG2ASCC1
MAD2L2ENSG00000116670.10526.32790664.20330-0.335702.405901.75710HepG2AUH
MAD2L2ENSG00000116670.10155.14840262.22750-0.757203.571002.71110HepG2CALR
MAD2L2ENSG00000116670.10211.82620335.75640-0.664501.985101.34230HepG2CNOT7
MAD2L2ENSG00000116670.10128.96590201.71920-0.645402.714802.03380HepG2CPSF6
MAD2L2ENSG00000116670.10210.06880298.01540-0.504502.540901.66800HepG2DDX24
MAD2L2ENSG00000116670.10172.16280352.30960-1.033104.255202.70090HepG2DDX27
MAD2L2ENSG00000116670.10245.77880376.64810-0.615902.228101.52780HepG2DDX55
MAD2L2ENSG00000116670.10141.53660229.06920-0.694602.332801.43710HepG2DDX59
MAD2L2ENSG00000116670.10396.88550517.56390-0.383001.861701.36340HepG2EIF2S1
MAD2L2ENSG00000116670.10363.18900556.94950-0.616803.293202.54570HepG2EIF4B
MAD2L2ENSG00000116670.10394.23550587.66320-0.575905.862304.72320HepG2EIF4G1
MAD2L2ENSG00000116670.10441.61860762.55330-0.7880012.0040010.89520HepG2ETF1
MAD2L2ENSG00000116670.1087.15460202.07930-1.213303.868402.66650HepG2FTO
MAD2L2ENSG00000116670.10314.19210412.55400-0.392902.097901.40590HepG2FUBP3
MAD2L2ENSG00000116670.10313.87600535.35520-0.770305.970705.00970HepG2G3BP1
MAD2L2ENSG00000116670.10412.83860568.47610-0.461502.724501.84230HepG2G3BP2
MAD2L2ENSG00000116670.10146.88150228.64540-0.638502.592001.96930HepG2GPKOW
MAD2L2ENSG00000116670.10378.03720547.42630-0.534104.817003.63790HepG2HNRNPA2B1
MAD2L2ENSG00000116670.10131.75690218.20230-0.727803.201602.53080HepG2HNRNPLL
MAD2L2ENSG00000116670.10365.68780544.14210-0.573403.714202.94160HepG2IGF2BP2
MAD2L2ENSG00000116670.10272.44420510.79410-0.906802.772001.78950HepG2IGF2BP3
MAD2L2ENSG00000116670.10246.68470547.37910-1.149909.847007.86920HepG2KHSRP
MAD2L2ENSG00000116670.10362.22420529.12560-0.546703.437802.63880HepG2PABPC4
MAD2L2ENSG00000116670.10268.00610479.09650-0.838107.362306.45090HepG2PCBP1
MAD2L2ENSG00000116670.10421.21420297.712900.500503.724002.88150HepG2PPIL4
MAD2L2ENSG00000116670.10172.84600290.32730-0.748203.175202.31550HepG2PRPF8
MAD2L2ENSG00000116670.10324.94430487.45620-0.585103.688703.07660HepG2PTBP1
MAD2L2ENSG00000116670.10431.60940563.82450-0.385502.318501.76640HepG2PUF60
MAD2L2ENSG00000116670.10437.19210598.09120-0.452103.343702.60800HepG2PUM2
MAD2L2ENSG00000116670.10375.11300528.01750-0.493303.500902.80980HepG2QKI
MAD2L2ENSG00000116670.10313.25210399.22520-0.349902.100801.34000HepG2RBM15
MAD2L2ENSG00000116670.10403.52920637.36200-0.659406.880506.15000HepG2RBM22
MAD2L2ENSG00000116670.10324.37240479.17570-0.562903.713602.94000HepG2RBM25
MAD2L2ENSG00000116670.10272.82360441.08590-0.693104.075603.27190HepG2RPLP0
MAD2L2ENSG00000116670.10122.10300287.17160-1.233806.007104.89620HepG2RRP9
MAD2L2ENSG00000116670.10181.79160263.04020-0.533002.322601.45740HepG2SERBP1
MAD2L2ENSG00000116670.10579.16460338.344400.775405.692304.70490HepG2SF3A3
MAD2L2ENSG00000116670.10112.08330240.30420-1.100305.165604.08780HepG2SNRNP70
MAD2L2ENSG00000116670.10479.16530719.89200-0.587307.236106.53120HepG2SRFBP1
MAD2L2ENSG00000116670.10334.86380556.70650-0.733308.339407.32800HepG2SRSF5
MAD2L2ENSG00000116670.10256.84050430.97220-0.746706.241105.47160HepG2SRSF9
MAD2L2ENSG00000116670.10432.87480625.06310-0.530105.537804.86090HepG2SSB
MAD2L2ENSG00000116670.10179.44430374.88180-1.062904.494103.66320HepG2SUPV3L1
MAD2L2ENSG00000116670.10146.36520212.73000-0.539502.115101.46930HepG2TARDBP
MAD2L2ENSG00000116670.10327.30210437.55780-0.418902.087601.35880HepG2TIA1
MAD2L2ENSG00000116670.10209.19380360.55990-0.785404.869404.04870HepG2U2AF1
MAD2L2ENSG00000116670.10413.91540583.07560-0.494302.466401.67990HepG2UBE2L3
MAD2L2ENSG00000116670.10440.52440289.696200.604605.289104.50530HepG2UTP3
MAD2L2ENSG00000116670.10161.80870258.53320-0.676104.340403.52920HepG2ZC3H8
MAD2L2ENSG00000116670.102756.057201509.149200.8688031.6057029.77610K562AGGF1
MAD2L2ENSG00000116670.102416.476201570.363100.621703.649502.89640K562AKAP8L
MAD2L2ENSG00000116670.101158.914302536.92040-1.1303023.4179021.89720K562AQR
MAD2L2ENSG00000116670.102025.779501647.736100.297902.889901.95790K562ATP5C1
MAD2L2ENSG00000116670.101061.098301476.73820-0.476902.244901.30720K562CNOT7
MAD2L2ENSG00000116670.102626.076603393.33920-0.369805.176103.83320K562CELF1
MAD2L2ENSG00000116670.101528.227301258.495400.280102.690601.41020K562DDX6
MAD2L2ENSG00000116670.10811.368901065.98970-0.393802.793101.45890K562DHX30
MAD2L2ENSG00000116670.10772.326901023.91960-0.406803.084201.66680K562DNAJC21
MAD2L2ENSG00000116670.10967.56800638.613900.599307.647906.33110K562EIF3G
MAD2L2ENSG00000116670.102391.526502759.51100-0.206502.385101.50940K562EIF4G2
MAD2L2ENSG00000116670.101441.89980981.173600.555306.167704.86730K562FIP1L1
MAD2L2ENSG00000116670.10868.459301257.60230-0.534103.057401.85790K562FKBP4
MAD2L2ENSG00000116670.101589.607101348.614500.237102.114701.57290K562FXR1
MAD2L2ENSG00000116670.10194.40740603.31280-1.6338013.3947011.58750K562G3BP2
MAD2L2ENSG00000116670.101189.772401426.54120-0.261802.363601.31750K562GLRX3
MAD2L2ENSG00000116670.10833.587901447.07870-0.795709.699608.63670K562HNRNPC
MAD2L2ENSG00000116670.101433.85070807.074600.829009.885707.89320K562HNRNPM
MAD2L2ENSG00000116670.102042.407401330.199600.618507.900806.57290K562HSPD1
MAD2L2ENSG00000116670.101837.011601149.950100.675702.561101.58610K562IGF2BP2
MAD2L2ENSG00000116670.10685.19210994.83230-0.537904.335502.45560K562ILF3
MAD2L2ENSG00000116670.10682.53050961.36540-0.494203.932802.16210K562KHDRBS1
MAD2L2ENSG00000116670.10396.40560556.27720-0.488802.448101.57610K562KRR1
MAD2L2ENSG00000116670.101570.061701208.019900.378103.552402.59400K562MAGOH
MAD2L2ENSG00000116670.102065.184201595.283500.372403.601402.32200K562MAK16
MAD2L2ENSG00000116670.102275.539201866.868700.285502.903801.96670K562MBNL1
MAD2L2ENSG00000116670.102400.518802941.31310-0.293102.571001.48490K562MSI2
MAD2L2ENSG00000116670.101274.446701499.82350-0.234902.520801.74770K562MTPAP
MAD2L2ENSG00000116670.101452.001701666.43020-0.198702.455201.74800K562NSUN2
MAD2L2ENSG00000116670.10960.302701418.70920-0.563003.028601.73210K562PABPC1
MAD2L2ENSG00000116670.101796.601801016.667800.821304.474503.13290K562PABPN1
MAD2L2ENSG00000116670.102036.105101113.891400.8701014.4900012.13240K562PPIG
MAD2L2ENSG00000116670.101599.345401173.706800.446305.205804.31860K562PTBP1
MAD2L2ENSG00000116670.102370.749003010.79350-0.344802.985002.13630K562PUF60
MAD2L2ENSG00000116670.102702.972303202.74370-0.244802.553301.53020K562PUM1
MAD2L2ENSG00000116670.102640.280201557.190900.761605.507304.77320K562PUS1
MAD2L2ENSG00000116670.102235.958201517.395800.559205.992905.14650K562RBM15
MAD2L2ENSG00000116670.101466.136701141.417100.361102.171101.45150K562RPS19
MAD2L2ENSG00000116670.10923.061101197.73000-0.375802.933001.44070K562SDAD1
MAD2L2ENSG00000116670.101642.36600929.869800.820603.470302.08330K562SF1
MAD2L2ENSG00000116670.10460.26470619.58300-0.428802.293301.41710K562SF3B1
MAD2L2ENSG00000116670.10853.89250626.945700.445603.724202.72730K562SF3B4
MAD2L2ENSG00000116670.101848.051601133.762500.704803.086401.67690K562SFPQ
MAD2L2ENSG00000116670.101770.668501150.683800.621708.174806.96920K562SRSF1
MAD2L2ENSG00000116670.101403.074101086.882100.368303.024901.91710K562SRSF5
MAD2L2ENSG00000116670.101087.443701479.88240-0.444505.385703.20130K562SRSF9
MAD2L2ENSG00000116670.10804.266501316.35720-0.710803.383801.56250K562STIP1
MAD2L2ENSG00000116670.101556.381001164.438200.418503.575502.76720K562TARDBP
MAD2L2ENSG00000116670.101446.508001123.266000.364803.456002.52630K562TIA1
MAD2L2ENSG00000116670.101526.513801102.562900.469303.971702.62790K562TRA2A
MAD2L2ENSG00000116670.10828.878701232.32600-0.572204.834402.42560K562TRNAU1AP
MAD2L2ENSG00000116670.10337.11940603.66520-0.840508.975907.52000K562U2AF2
MAD2L2ENSG00000116670.101164.637801511.92390-0.376503.718002.70340K562WDR3
MAD2L2ENSG00000116670.101302.778101572.23290-0.271203.427302.49320K562WDR43
MAD2L2ENSG00000116670.102210.482202858.09220-0.370703.855802.80700K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAD2L2 is not available on ENCORE database.





3 RBPs can affect the splicing of MAD2L2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSMAD2L2ENSG00000116670.10chr1-1173571311735910117357131173578811736102117363320.051000.000000.00000longerK562AQR
A3SSMAD2L2ENSG00000116670.10chr1-1173690411737052117369041173700511737599117376710.051000.000000.00000longerK562AQR
MXEMAD2L2ENSG00000116670.10chr1-11737599117376711174040911740528117369041173700511740618117411880.121000.000230.006391includedK562DROSHA
MXEMAD2L2ENSG00000116670.10chr1-1174040911740496117406181174067011737599117376711174109511741495-0.152000.001500.065712includedK562PHF6

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAD2L2 is not avaliable on ENCORE database.