LSR

General Information

Gene Name       : LSR
Gene ID             : ENSG00000105699.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LSR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LSRENSG00000105699.162.068.475.27ENCSR000AEF
HepG2LSRENSG00000105699.16119.3216.3167.81ENCSR985KAT
K562LSRENSG00000105699.1644.5118.8131.66ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LSR is not avaliable on ENCORE database.



Proteins bound to RNA
  • LSR RNA is bound by 17 proteins.  







eCLIP assay for LSR is not avaliable on ENCORE database.





17 proteins are bound to LSR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr193575880035758850+3'-UTR3.0868819.75402HepG2LARP4
chr193575880535758857+3'-UTR3.245595.21454K562TIA1
chr193575879835758848+3'-UTR3.297474.33754HepG2TIAL1
chr193573990935740011+5'-UTR,CDS,intron-Distal,intron-Proximal6.70434400.00000HepG2DDX3X
chr193574156135741570+CDS,intron-Proximal4.253896.48405K562AQR
chr193575831935758375+CDS3.362538.50909HepG2LARP4
chr193575838235758486+CDS5.1198814.16470HepG2SND1
chr193574121535741267+CDS,intron-Proximal3.5823812.79836K562DDX3X
chr193574144435741509+CDS3.285014.45064HepG2GRWD1
chr193575803935758191+CDS3.1137410.37156HepG2SND1
chr193575828735758318+CDS4.206356.49041HepG2RPS3
chr193575748435757607+CDS,intron-Distal,intron-Proximal3.903199.56233HepG2EFTUD2
chr193575833835758372+CDS3.037744.81750HepG2SND1
chr193575810235758151+CDS5.0692913.37480HepG2RPS3
chr193574001135740036+CDS,intron-Distal,intron-Proximal4.5084126.85189HepG2DDX3X
chr193574126135741326+CDS3.5068420.78971HepG2DDX3X
chr193574121635741256+CDS,intron-Proximal3.9630030.17724HepG2DDX3X
chr193574989635749931+CDS,intron-Distal3.7358011.49605HepG2RPS3
chr193575804235758088+CDS3.890045.44144HepG2RPS3
chr193575819735758244+CDS3.953267.88496HepG2RPS3
chr193575855335758616+CDS3.961756.74349HepG2DDX55
chr193575819135758256+CDS3.127434.88696HepG2SND1
chr193574132635741379+CDS3.549167.49943HepG2DDX3X
chr193575857735758614+CDS5.2522011.07772HepG2RPS3
chr193573999435740035+CDS,intron-Distal,intron-Proximal3.6678710.49508K562DDX3X
chr193575849235758619+CDS3.128065.66231K562PABPC4
chr193575813235758192+CDS3.662994.62987HepG2NOL12
chr193575736435757418+CDS3.142663.51818HepG2LIN28B
chr193575815135758197+CDS4.607149.69624HepG2RPS3
chr193573992535739994+CDS,intron-Distal,intron-Proximal4.738966.82597K562DDX3X
chr193575848035758633+CDS3.4527221.56607HepG2LARP4
chr193575000035750066+intron-Distal,intron-Proximal4.035845.26367K562AQR
chr193574759635747707+intron-Distal3.985933.91772K562TARDBP
chr193574446835744647+intron-Distal3.094373.20171HepG2ILF3
chr193574158335741647+intron-Proximal4.2828510.42007HepG2RBM22
chr193574158935741628+intron-Proximal4.103318.79285K562AQR
chr193574156235741633+intron-Proximal3.816063.15006K562RBM15
chr193574157035741589+intron-Proximal4.331156.99120K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LSR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LSR is not available on ENCORE database.

  • 128 RBPs can affect the levels of LSR.  








The Knockdown/knockout RNA-Seq assay for LSR is not available on ENCORE database.





128 RBPs can affect the gene expression of LSR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LSRENSG00000105699.121810.663302676.17600-0.563702.803101.85550HepG2ABCF1
LSRENSG00000105699.121459.77970791.248800.883404.284503.07320HepG2ADAR
LSRENSG00000105699.121931.419401445.717100.417804.045403.33770HepG2BOP1
LSRENSG00000105699.122581.543702004.324100.365003.295801.95970HepG2BUD13
LSRENSG00000105699.122182.742201327.218400.7176010.305409.06100HepG2CPSF6
LSRENSG00000105699.123745.455402202.972500.7656014.6350012.34460HepG2CPSF7
LSRENSG00000105699.121358.25450811.427300.743108.391306.63610HepG2YBX3
LSRENSG00000105699.122001.430101238.087800.6928016.2008014.89900HepG2CELF1
LSRENSG00000105699.121695.698201331.188800.349102.693001.96010HepG2DAZAP1
LSRENSG00000105699.121444.46710909.284900.667602.451201.71930HepG2DDX55
LSRENSG00000105699.123399.326201790.157600.925105.938505.06180HepG2DDX6
LSRENSG00000105699.121632.395301954.70870-0.260001.986701.39830HepG2DKC1
LSRENSG00000105699.121457.62620796.728900.871405.911004.91570HepG2DNAJC21
LSRENSG00000105699.121442.69740789.739900.8692027.0616025.22330HepG2DNAJC2
LSRENSG00000105699.12926.242301313.35080-0.503807.460306.20640HepG2EIF4G1
LSRENSG00000105699.121538.811301258.096800.290502.047101.33880HepG2EIF4G2
LSRENSG00000105699.122076.946802702.10490-0.379602.382901.66450HepG2FIP1L1
LSRENSG00000105699.121479.181002193.70440-0.568603.916202.98900HepG2FUBP3
LSRENSG00000105699.121289.97540938.599900.458702.334501.40200HepG2GNB2L1
LSRENSG00000105699.122388.895601950.514100.292402.948701.94380HepG2HDGF
LSRENSG00000105699.121301.25340778.873100.740303.390801.86790HepG2HNRNPA0
LSRENSG00000105699.121701.815801278.080200.413006.775705.71920HepG2HNRNPF
LSRENSG00000105699.122767.590401803.421500.617803.075002.34010HepG2HNRNPK
LSRENSG00000105699.122075.365601212.593100.7752012.2516010.92970HepG2HNRNPL
LSRENSG00000105699.121987.074501435.709500.468804.356203.58240HepG2HNRNPLL
LSRENSG00000105699.121488.914201863.80820-0.324002.386601.50240HepG2HNRNPM
LSRENSG00000105699.121322.90790888.803300.573705.032104.23450HepG2HNRNPU
LSRENSG00000105699.121231.50670907.880500.439807.719206.55930HepG2ILF2
LSRENSG00000105699.122274.845901867.581500.284504.835703.49430HepG2KIF1C
LSRENSG00000105699.121213.93880919.808700.400202.868201.71500HepG2LARP7
LSRENSG00000105699.122909.148701929.857000.592002.497201.89500HepG2MATR3
LSRENSG00000105699.121101.53300831.633600.405402.775301.35490HepG2NIP7
LSRENSG00000105699.121959.287501320.007300.569709.752508.34900HepG2NOL12
LSRENSG00000105699.121572.16700758.817401.0508010.308907.53420HepG2NOLC1
LSRENSG00000105699.122026.97320835.429601.2786010.252208.09930HepG2NONO
LSRENSG00000105699.121562.791601273.088000.295702.056701.40750HepG2NSUN2
LSRENSG00000105699.121323.62370840.869600.654402.233901.45110HepG2PABPC1
LSRENSG00000105699.121140.19470879.743800.374004.429203.38800HepG2PARN
LSRENSG00000105699.122001.62940792.738801.336208.678107.42080HepG2PPIL4
LSRENSG00000105699.121105.113701474.35590-0.415903.727302.84140HepG2PRPF4
LSRENSG00000105699.121387.116501985.26940-0.517207.013406.22240HepG2PTBP1
LSRENSG00000105699.122026.693701260.078900.6855010.904309.82640HepG2PUF60
LSRENSG00000105699.121925.953801337.648700.5258013.6537012.54690HepG2PUM1
LSRENSG00000105699.122523.007601336.659600.916403.881603.09040HepG2PUM2
LSRENSG00000105699.121827.812202081.07510-0.187202.086001.53320HepG2PUS1
LSRENSG00000105699.121191.158502149.87390-0.8519019.9442018.48250HepG2QKI
LSRENSG00000105699.121163.60800724.805700.682803.327401.43510HepG2RBM14
LSRENSG00000105699.121623.071002001.31390-0.302203.366902.81130HepG2RBM22
LSRENSG00000105699.121466.471501109.185100.402702.662301.68810HepG2RBM27
LSRENSG00000105699.121478.132202209.32780-0.5798012.3738011.38440HepG2NELFE
LSRENSG00000105699.121728.189202057.84550-0.251901.958701.42780HepG2RECQL
LSRENSG00000105699.121837.95410791.509501.2153051.6882049.45590HepG2SAFB2
LSRENSG00000105699.123422.866502401.071200.511403.982903.16720HepG2SF3A3
LSRENSG00000105699.122145.729401421.023500.594407.513306.40080HepG2SF3B1
LSRENSG00000105699.121709.63760866.484300.980302.841101.36780HepG2SFPQ
LSRENSG00000105699.122314.895601208.258800.9379039.9022037.90150HepG2SLBP
LSRENSG00000105699.121353.38650923.018600.5520011.7151010.53530HepG2SMN1
LSRENSG00000105699.121812.97530798.044201.183704.602602.81760HepG2SNRNP200
LSRENSG00000105699.122199.138601581.154000.475902.708401.93520HepG2SNRNP70
LSRENSG00000105699.12858.915602157.30010-1.3286052.1545050.67260HepG2SRSF1
LSRENSG00000105699.123097.986201244.167501.3161068.8152066.32710HepG2SRSF5
LSRENSG00000105699.121529.998201255.642400.285003.399802.63950HepG2SRSF7
LSRENSG00000105699.12957.929701962.56170-1.0347037.2304035.85110HepG2SSB
LSRENSG00000105699.121932.826101414.941400.449909.290708.26540HepG2SUCLG1
LSRENSG00000105699.122373.374201823.871200.379803.603002.53900HepG2SUPT6H
LSRENSG00000105699.12588.606701939.27690-1.7201051.9442049.90830HepG2TAF15
LSRENSG00000105699.121887.729201399.580400.431604.056503.19760HepG2TARDBP
LSRENSG00000105699.121252.50380606.523901.046104.258203.05790HepG2TFIP11
LSRENSG00000105699.121284.927601781.70690-0.471602.233101.48030HepG2TIA1
LSRENSG00000105699.122399.57060871.362501.4613074.6478072.30860HepG2TRIM56
LSRENSG00000105699.122728.374001231.075201.148006.094104.73010HepG2TUFM
LSRENSG00000105699.121707.127902310.99740-0.436902.603301.99300HepG2U2AF1
LSRENSG00000105699.121661.86500927.690500.841002.403601.49260HepG2U2AF2
LSRENSG00000105699.123047.892901303.094401.225807.419706.02220HepG2UBE2L3
LSRENSG00000105699.121025.45400806.426500.346503.639903.00540K562AGGF1
LSRENSG00000105699.121117.31670839.125100.413003.056002.36820K562AKAP8L
LSRENSG00000105699.12432.870601401.39730-1.6949037.0755035.12850K562AQR
LSRENSG00000105699.121151.77480880.447600.387404.285403.12140K562ATP5C1
LSRENSG00000105699.12880.90600579.187600.604903.186401.75950K562BCCIP
LSRENSG00000105699.12497.68180813.85320-0.709506.126604.81720K562BOP1
LSRENSG00000105699.12662.45770911.73920-0.460803.118501.59240K562BUD13
LSRENSG00000105699.12985.27380777.719300.341202.351901.39610K562CCAR1
LSRENSG00000105699.12714.34430963.71820-0.432004.006402.55010K562CCDC124
LSRENSG00000105699.12664.21140941.31300-0.503005.056403.00190K562CEBPZ
LSRENSG00000105699.12539.46530340.452500.664002.687901.42930K562CIRBP
LSRENSG00000105699.12776.952501103.82850-0.506602.542101.53140K562CNOT7
LSRENSG00000105699.121636.260101345.915400.281702.920501.77990K562CPEB4
LSRENSG00000105699.12627.64280424.706900.563402.318101.36780K562CSTF2
LSRENSG00000105699.121113.973201987.54520-0.8353017.9303015.64860K562CELF1
LSRENSG00000105699.121295.82830946.159200.453604.131102.32340K562DDX19B
LSRENSG00000105699.121885.154301392.684500.436707.161606.18120K562DDX47
LSRENSG00000105699.121824.830301119.093600.7053015.3323013.84580K562EIF2S2
LSRENSG00000105699.12477.44190231.848101.0420012.2801010.57940K562EIF3G
LSRENSG00000105699.12459.61230591.51840-0.364002.066301.35360K562EIF4A3
LSRENSG00000105699.12713.47770532.694900.421503.885002.47760K562EIF4B
LSRENSG00000105699.121328.230301616.36520-0.283203.010602.03130K562EIF4G2
LSRENSG00000105699.121233.90080940.945300.390903.303002.37190K562FIP1L1
LSRENSG00000105699.12282.43380562.86210-0.994909.700307.41330K562FKBP4
LSRENSG00000105699.12626.29750880.46530-0.491404.035502.99870K562FMR1
LSRENSG00000105699.12135.92300204.97110-0.592602.922801.54140K562FUS
LSRENSG00000105699.12793.68350615.154300.367503.260302.61240K562FXR1
LSRENSG00000105699.1239.47250133.60170-1.759008.682707.28570K562G3BP2
LSRENSG00000105699.12978.853901446.19580-0.563108.818106.87570K562GLRX3
LSRENSG00000105699.12819.25390647.956500.338302.270801.72240K562HNRNPC
LSRENSG00000105699.12704.88400318.054501.148002.973101.89810K562IGF2BP2
LSRENSG00000105699.12664.691501007.94140-0.600703.009501.51970K562ILF2
LSRENSG00000105699.12343.64550705.46500-1.037709.188007.38190K562KRR1
LSRENSG00000105699.12593.16430333.857000.829105.241404.07580K562MAGOH
LSRENSG00000105699.12541.82240333.118000.701703.981202.85930K562MATR3
LSRENSG00000105699.121398.956701722.86760-0.300502.435501.37860K562MSI2
LSRENSG00000105699.12963.494101520.48300-0.6582013.9731012.32420K562MTPAP
LSRENSG00000105699.12855.87010441.871100.953704.614502.82700K562NONO
LSRENSG00000105699.121009.408601689.41160-0.7430023.5710021.71690K562NSUN2
LSRENSG00000105699.121254.36980847.807600.565107.042605.77590K562POLR2G
LSRENSG00000105699.121364.574801068.242900.353102.819401.98950K562PPIG
LSRENSG00000105699.12609.03460435.920700.482402.545001.82570K562PRPF8
LSRENSG00000105699.12868.18810580.986100.579402.409001.57100K562PSIP1
LSRENSG00000105699.12801.79150324.393301.3054020.8945019.14250K562PTBP1
LSRENSG00000105699.121422.674101875.92210-0.399004.843503.40120K562PUM1
LSRENSG00000105699.1237.55530127.46770-1.763006.461704.21250K562RAVER1
LSRENSG00000105699.121117.08460810.834000.462205.403504.60000K562RBM15
LSRENSG00000105699.121079.61240530.196001.0258018.2344015.71890K562RCC2
LSRENSG00000105699.12672.50300443.890300.599203.713102.76380K562RPS19
LSRENSG00000105699.12606.77740284.040801.095003.689402.51260K562RPS3
LSRENSG00000105699.121215.56960755.498400.686009.014507.12540K562SAFB
LSRENSG00000105699.121083.166201666.99070-0.622006.405205.20640K562SF3A3
LSRENSG00000105699.12495.81690785.72700-0.664205.215303.85730K562SF3B1
LSRENSG00000105699.12642.38570856.51850-0.415002.910001.61360K562SLBP
LSRENSG00000105699.12130.82090212.89610-0.702603.226701.49010K562SND1
LSRENSG00000105699.12813.25310502.599100.694207.077305.21860K562SRFBP1
LSRENSG00000105699.12677.03230435.486800.636503.104401.36480K562SRP68
LSRENSG00000105699.121252.768501707.86550-0.447104.965003.75490K562SRPK2
LSRENSG00000105699.12822.08000318.059101.369907.970006.77700K562SRSF1
LSRENSG00000105699.12428.31800274.215800.643304.302802.94340K562SRSF4
LSRENSG00000105699.12526.22310300.495600.808204.609703.19290K562SRSF5
LSRENSG00000105699.12719.14950965.33620-0.424703.565302.22340K562SRSF7
LSRENSG00000105699.12158.58580239.15390-0.592703.017601.67120K562SSB
LSRENSG00000105699.12681.452501234.49430-0.8572011.533608.69290K562SSRP1
LSRENSG00000105699.12806.841301129.04980-0.484803.779502.27900K562STAU1
LSRENSG00000105699.12428.47350738.97380-0.786303.383101.75160K562SUPT6H
LSRENSG00000105699.12738.31310321.798401.198005.091604.11720K562TARDBP
LSRENSG00000105699.12832.53300310.436701.4231013.6441011.70450K562TIA1
LSRENSG00000105699.12634.53330304.863101.057404.925803.39260K562TRA2A
LSRENSG00000105699.121130.09690803.603600.491803.985501.84120K562TRNAU1AP
LSRENSG00000105699.1262.43610133.73310-1.098905.127904.03910K562U2AF2
LSRENSG00000105699.121566.669101791.31740-0.193302.073301.44520K562UPF1
LSRENSG00000105699.12960.329301532.77610-0.6745010.243908.51910K562WDR3
LSRENSG00000105699.121331.735501660.23030-0.318102.823701.51620K562WRN
LSRENSG00000105699.12673.72070454.926800.566402.980901.70840K562XRN2
LSRENSG00000105699.12990.725501578.80300-0.672309.389807.68240K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LSR is not available on ENCORE database.





24 RBPs can affect the splicing of LSR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELSRENSG00000105699.12chr19+357534483575359535749847357499673575726135757435-0.123000.000280.03712excludedK562FMR1
SELSRENSG00000105699.12chr19+3575344835753595357412173574156235757261357574350.066000.000000.00001includedHepG2U2AF2
SELSRENSG00000105699.12chr19+357498473574996735741217357415623575726135757435-0.083000.002790.02886excludedK562AQR
SELSRENSG00000105699.12chr19+357534483575359535749847357499673575726135757435-0.143000.003220.04428excludedK562PUS1
SELSRENSG00000105699.12chr19+357528273575288435749847357499673575726135757330-0.074000.000700.04365excludedHepG2NCBP2
SELSRENSG00000105699.12chr19+3574984735749967357412173574156235757261357574350.063000.000870.04114includedHepG2SFPQ
SELSRENSG00000105699.12chr19+357498473574996735741217357415623575726135757435-0.105000.000210.05119excludedK562GPKOW
SELSRENSG00000105699.12chr19+357534483575359535741217357415623575726135757435-0.193000.000240.03408excludedHepG2PCBP2
SELSRENSG00000105699.12chr19+3574984735749967357412173574156235757261357574350.067000.000800.08341includedHepG2HNRNPUL1
SELSRENSG00000105699.12chr19+357534483575359535749847357499673575726135757435-0.174000.000000.00000excludedHepG2SF3A3
SELSRENSG00000105699.12chr19+3575282735752884357498473574996735753448357535950.339000.000000.00037includedK562LARP7
SELSRENSG00000105699.12chr19+357534483575359535749847357499673575726135757435-0.230000.000000.00080excludedK562LARP7
SELSRENSG00000105699.12chr19+357534483575359535749847357499673575726135757435-0.140000.000070.01875excludedK562UPF1
SELSRENSG00000105699.12chr19+357534483575359535749847357499673575726135757435-0.132000.002950.06292excludedK562AGGF1
SELSRENSG00000105699.12chr19+3575282735752884357498473574996735753448357535950.177000.000290.05841includedHepG2DDX55
SELSRENSG00000105699.12chr19+3575344835753595357498473574996735757261357574350.188000.000000.00027includedHepG2HNRNPC
SELSRENSG00000105699.12chr19+3575344835753595357498473574996735757261357574350.159000.000050.09247includedHepG2DDX52
SELSRENSG00000105699.12chr19+3575344835753595357498473574996735757261357574350.128000.000120.09784includedHepG2NOLC1
RILSRENSG00000105699.12chr19+3575758135757870357575813575764135757738357578700.154000.000030.00027includedK562PUS1
RILSRENSG00000105699.12chr19+3575758135757870357575813575764135757738357578700.191000.000210.01095includedK562SF3B1
RILSRENSG00000105699.12chr19+3575758135757870357575813575764135757738357578700.120000.000470.04187includedK562PHF6
RILSRENSG00000105699.12chr19+3575758135757870357575813575764135757738357578700.108000.000880.02390includedHepG2FTO
RILSRENSG00000105699.12chr19+3575758135757870357575813575764135757738357578700.085000.000000.00003includedK562AQR
MXELSRENSG00000105699.12chr19+35749847357499673575344835753595357412173574156235757261357574350.131000.000360.009161includedK562PUS1
MXELSRENSG00000105699.12chr19+35749847357499673575344835753595357412173574156235757261357574350.115000.003720.097931includedK562AGGF1
MXELSRENSG00000105699.12chr19+3574984735749967357534483575359535741217357415623575726135757435-0.136000.000010.002642includedHepG2NOLC1
MXELSRENSG00000105699.12chr19+3574984735749967357534483575359535741217357415623575726135757435-0.173000.000000.001022includedHepG2BCCIP
MXELSRENSG00000105699.12chr19+35749847357499673575344835753595357412173574156235757261357574350.109000.000100.006241includedHepG2SF3A3
MXELSRENSG00000105699.12chr19+35749847357499673575344835753595357412173574156235757261357574350.125000.000390.046381includedHepG2HLTF
MXELSRENSG00000105699.12chr19+3574984735749967357534483575359535741217357415623575726135757435-0.130000.000660.024752includedHepG2XRN2
MXELSRENSG00000105699.12chr19+3574984735749967357534483575359535741217357415623575726135757435-0.110000.002360.049532includedHepG2DDX55
MXELSRENSG00000105699.12chr19+3574984735749967357534483575359535741217357415623575726135757435-0.127000.004650.028712includedHepG2U2AF2
MXELSRENSG00000105699.12chr19+3574984735749967357534483575359535741217357415623575726135757435-0.113000.000250.022422includedHepG2SRSF7
MXELSRENSG00000105699.12chr19+35749847357499673575344835753595357412173574156235757261357574350.109000.000760.070521includedK562FMR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LSR is not avaliable on ENCORE database.