DEK

General Information

Gene Name : DEK
Gene ID : ENSG00000124795.15
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: DEK)

Not Available

Antibody Validation

Thermo Fisher: 720215

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	DEK	ENSG00000124795.15	234.54	212.46	223.50	ENCSR000AEF
HepG2	DEK	ENSG00000124795.15	109.18	187.98	148.58	ENCSR985KAT
K562	DEK	ENSG00000124795.15	148.24	187.59	167.92	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
eCLIP	eCLIP: 4146	ENCSR332LFL	DEK	HepG2	Released	ENCAB872AQT	ENCSR558OKC
eCLIP	eCLIP: 4004	ENCSR691HQP	DEK	K562	Released	ENCAB872AQT	ENCSR624YWO

eCLIP

RBP	Exp_UID	Cell_Line	ENCODE_ACCESSION	Control_ENCODE_ACCESSION	ENCODE_Antibody_ID	Antibody	Lot_num	Status	Project
DEK	4146	HepG2	ENCSR332LFL	ENCSR558OKC	ENCAB872AQT	720215	SD249202	Released	ENCODE4
DEK	4004	K562	ENCSR691HQP	ENCSR624YWO	ENCAB872AQT	720215	SD249202	Released	ENCODE4

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
DEK	ENCAB872AQT	720215	SD249202			Released, ENCODE4	BGHcLV45-19, Submitted, ENCORE2	BGKcLV44-13, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
DEK	K562	CRISPR	BGKcLV13-13,BGKcLV13-14	BGKcLV13-1,BGKcLV13-2	79.0,80.0	NotSatisfied	ENCODE4
DEK	K562	CRISPR	BGKcLV13-15,BGKcLV13-16	BGKcLV13-1,BGKcLV13-2		NotSatisfied	ENCODE4
DEK	K562	CRISPR	BGKcLV13-17,BGKcLV13-18	BGKcLV13-1,BGKcLV13-2		NotSatisfied	ENCODE4
DEK	K562	CRISPR	DEK-BGKcLV44-13,DEK-BGKcLV44-14	NT-BGKcLV44-1,NT-BGKcLV44-2	72.0,76.3	Submitting	ENCORE2
DEK	K562	CRISPR	BGKcLV44-15,BGKcLV44-16	BGKcLV44-1,BGKcLV44-2	0.0,0.0	NotSatisfied	ENCORE2
DEK	HepG2	CRISPR	BGHcLV14-13,BGHcLV14-14	BGHcLV14-1,BGHcLV14-2		NotSatisfied	ENCODE4
DEK	HepG2	CRISPR	BGHcLV14-15,BGHcLV14-16	BGHcLV14-1,BGHcLV14-2		NotSatisfied	ENCODE4
DEK	HepG2	CRISPR	BGHcLV14-17,BGHcLV14-18	BGHcLV14-1,BGHcLV14-2	no clear band on the position,	NotSatisfied	ENCODE4
DEK	HepG2	CRISPR	DEK-BGHcLV45-19,DEK-BGHcLV45-20	NT-BGHcLV45-1,NT-BGHcLV45-2	72.8,80.8	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
DEK	Product_ID: 720215 Lot_ID: SD249202 Source: Thermo Fisher Target Name: DEK-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for DEK is not avaliable on ENCORE database.

Proteins bound to RNA

DEK RNA is bound by 40 proteins.

CanvasJS.com

eCLIP assay for DEK is not avaliable on ENCORE database.

40 proteins are bound to DEK RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr6	18225368	18225416	-	3'-UTR,intron-Distal	5.51177	400.00000	K562	PUM2
chr6	18225416	18225471	-	3'-UTR,intron-Distal	5.33378	400.00000	K562	PUM2
chr6	18255964	18256078	-	CDS,intron-Distal,intron-Proximal	4.47181	400.00000	K562	PUM2
chr6	18225614	18225671	-	3'-UTR,intron-Distal,intron-Proximal	3.52219	71.02435	K562	PUM2
chr6	18225279	18225308	-	3'-UTR,intron-Distal	4.14604	65.63549	K562	PUM2
chr6	18225311	18225332	-	3'-UTR,intron-Distal	4.60170	54.57380	K562	PUM2
chr6	18255961	18255992	-	CDS,intron-Distal,intron-Proximal	3.13827	35.10149	K562	UCHL5
chr6	18258538	18258593	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.55720	34.39154	K562	UCHL5
chr6	18225686	18225706	-	3'-UTR,intron-Distal,intron-Proximal	3.93732	30.82177	K562	PUM2
chr6	18249891	18249999	-	CDS,intron-Distal,intron-Proximal	3.24846	30.53879	K562	ZNF622
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 140 entries

eCLIP assay for DEK is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for DEK is not available on ENCORE database.
147 RBPs can affect the levels of DEK.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for DEK is not available on ENCORE database.

147 RBPs can affect the gene expression of DEK :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
DEK	ENSG00000124795.10	1710.92170	5385.61190	-1.65430	176.18180	173.79170	HepG2	ZNF622
DEK	ENSG00000124795.10	2799.16410	7258.96230	-1.37480	100.71450	97.76010	HepG2	SRSF5
DEK	ENSG00000124795.10	2224.84030	9341.80240	-2.07000	98.03670	95.70180	HepG2	BOP1
DEK	ENSG00000124795.10	1351.45440	4766.53690	-1.81840	96.76100	94.62120	HepG2	TIAL1
DEK	ENSG00000124795.10	1089.48200	5719.99460	-2.39240	89.79630	86.67620	HepG2	DDX3X
DEK	ENSG00000124795.10	2049.20210	9722.30050	-2.24620	80.55300	77.74670	HepG2	GPKOW
DEK	ENSG00000124795.10	2260.63870	8576.39070	-1.92360	77.63210	74.85780	HepG2	CPSF6
DEK	ENSG00000124795.10	2202.57640	4896.86490	-1.15270	69.99990	67.55400	HepG2	UPF1
DEK	ENSG00000124795.10	2966.32270	9042.53950	-1.60810	59.12430	56.60650	HepG2	TARDBP
DEK	ENSG00000124795.10	1982.70990	7770.35360	-1.97050	57.98530	56.22270	HepG2	RBM22
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 180 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for DEK is not available on ENCORE database.

51 RBPs can affect the splicing of DEK :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	DEK	ENSG00000124795.10	chr6	-	18258534	18258636			18258183	18258293	18264073	18264227	-0.08300	0.00000	excluded	K562	SF3B4
SE	DEK	ENSG00000124795.10	chr6	-	18226404	18226473			18225700	18225961	18236682	18236831	-0.05100	0.00000	excluded	HepG2	U2AF2
SE	DEK	ENSG00000124795.10	chr6	-	18255961	18256082			18249881	18250070	18258183	18258293	-0.09900	0.00000	excluded	K562	SUPV3L1
SE	DEK	ENSG00000124795.10	chr6	-	18258534	18258636			18258183	18258293	18264073	18264227	-0.07000	0.00000	excluded	K562	PUS1
SE	DEK	ENSG00000124795.10	chr6	-	18226404	18226473			18225700	18225961	18236682	18236831	-0.05300	0.00000	excluded	K562	U2AF2
SE	DEK	ENSG00000124795.10	chr6	-	18258534	18258657			18258183	18258293	18264073	18264227	-0.06400	0.00000	excluded	K562	SF3B1
SE	DEK	ENSG00000124795.10	chr6	-	18244738	18244834			18237611	18237747	18249881	18250070	0.05800	0.00000	included	K562	HNRNPC
A3SS	DEK	ENSG00000124795.10	chr6	-	18256591	18256770			18256591	18256686	18258183	18258293	0.07000	0.00000	longer	K562	AQR
MXE	DEK	ENSG00000124795.10	chr6	-	18258534	18258636	18264073	18264227	18258183	18258293	18264615	18264772	0.09300	0.00002	1included	HepG2	MATR3
MXE	DEK	ENSG00000124795.10	chr6	-	18258183	18258293	18258534	18258636	18256591	18256686	18264073	18264227	0.14600	0.00000	1included	HepG2	FTO

Showing 1 to 10 of 79 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

DEK

General Information

Functions

Localization

Domains (AlphaFold: DEK)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for DEK is not avaliable on ENCORE database.

40 proteins are bound to DEK RNA:

eCLIP assay for DEK is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for DEK is not available on ENCORE database.

147 RBPs can affect the gene expression of DEK :

The Knockdown/knockout RNA-Seq assay for DEK is not available on ENCORE database.

51 RBPs can affect the splicing of DEK :

The Knockdown/knockout RNA-Seq assay for DEK is not avaliable on ENCORE database.