RPS6KA1

General Information

Gene Name       : RPS6KA1
Gene ID             : ENSG00000117676.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RPS6KA1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RPS6KA1ENSG00000117676.1345.5450.9448.24ENCSR000AEF
HepG2RPS6KA1ENSG00000117676.1324.7018.6421.67ENCSR985KAT
K562RPS6KA1ENSG00000117676.1335.3931.1733.28ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RPS6KA1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RPS6KA1 RNA is bound by 15 proteins.  







eCLIP assay for RPS6KA1 is not avaliable on ENCORE database.





15 proteins are bound to RPS6KA1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12690143826901496+3'-UTR4.346395.24353K562UPF1
chr12690063826900658+3'-UTR,CDS3.725726.21348K562YBX3
chr12687983326879924+3'-UTR,5'-UTR,CDS,intron-Proximal5.180396.40247K562SF3B4
chr12688807326888164+3'-UTR,CDS,intron-Proximal4.305543.59941K562UCHL5
chr12690145226901479+3'-UTR5.728796.59792K562PABPC4
chr12690093926900991+3'-UTR4.873549.59522K562PABPC4
chr12687820726878256+3'-UTR,CDS,intron-Proximal5.167366.44303K562AQR
chr12688119126881265+5'-UTR,CDS,intron-Proximal5.297847.36776HepG2PRPF8
chr12685626526856377+5'-UTR3.733065.29681HepG2NCBP2
chr12688158926881651+5'-UTR,CDS,intron-Proximal4.855649.04180K562SF3B4
chr12687374426873806+5'-UTR,CDS,intron-Distal,intron-Proximal4.9643510.76264HepG2PRPF8
chr12688211426882163+5'-UTR,CDS,intron-Proximal3.942344.89208K562AQR
chr12688071726880780+5'-UTR,CDS,intron-Proximal4.220534.16174HepG2PRPF8
chr12688540526885470+5'-UTR,CDS,intron-Proximal4.361646.81564HepG2PRPF8
chr12685625926856334+5'-UTR4.432525.48791HepG2DDX3X
chr12688071926880755+5'-UTR,CDS,intron-Proximal4.395795.97994K562AQR
chr12687375926873805+5'-UTR,CDS,intron-Distal,intron-Proximal6.0804013.28065K562AQR
chr12688070526880773+5'-UTR,CDS,intron-Proximal4.498695.02679K562BUD13
chr12688161026881671+5'-UTR,CDS,intron-Proximal4.050816.40042K562EFTUD2
chr12688121926881283+5'-UTR,CDS,intron-Proximal5.402248.34848K562PRPF8
chr12687376026873841+5'-UTR,CDS,intron-Distal,intron-Proximal3.088684.63145K562BUD13
chr12688072726880835+5'-UTR,CDS,intron-Proximal3.830296.38859K562EFTUD2
chr12688122526881271+5'-UTR,CDS,intron-Proximal4.549854.48002K562AQR
chr12688004026880137+intron-Distal,intron-Proximal3.658313.77649K562EFTUD2
chr12686707826867129+intron-Distal4.145253.48745HepG2ILF3
chr12688327826883324+intron-Distal,intron-Proximal4.378394.58968K562PRPF8
chr12688326726883329+intron-Distal,intron-Proximal4.860594.65563K562AQR
chr12686178926861914+intron-Distal4.154854.72426K562LIN28B
chr12688430126884355+intron-Distal4.602674.59452HepG2PCBP2
chr12688327226883323+intron-Distal,intron-Proximal5.750887.24749HepG2EFTUD2
chr12686893826869034+intron-Distal3.758095.39069K562TARDBP
chr12686706326867136+intron-Distal3.390583.59765K562ILF3
chr12688076626880783+intron-Proximal5.331155.69951K562AQR
chr12689878826898860+intron-Proximal4.961414.65563K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RPS6KA1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RPS6KA1 is not available on ENCORE database.

  • 82 RBPs can affect the levels of RPS6KA1.  








The Knockdown/knockout RNA-Seq assay for RPS6KA1 is not available on ENCORE database.





82 RBPs can affect the gene expression of RPS6KA1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RPS6KA1ENSG00000117676.9854.44110519.877800.716706.190104.66310HepG2AKAP8
RPS6KA1ENSG00000117676.91146.59260946.672100.276302.832702.13960HepG2AUH
RPS6KA1ENSG00000117676.9633.05950472.453500.422102.679402.08970HepG2BOP1
RPS6KA1ENSG00000117676.9760.66760594.298600.356002.009301.34360HepG2CIRBP
RPS6KA1ENSG00000117676.9923.61160636.549000.536902.326701.62870HepG2CNOT7
RPS6KA1ENSG00000117676.9332.46480433.72010-0.383601.938601.35210HepG2CPSF6
RPS6KA1ENSG00000117676.91081.34370858.750000.332403.394502.69750HepG2CELF1
RPS6KA1ENSG00000117676.9345.61930473.87390-0.455302.688301.32000HepG2DDX28
RPS6KA1ENSG00000117676.9444.29830581.37910-0.388002.257901.34400HepG2DDX5
RPS6KA1ENSG00000117676.9855.33080622.183800.459002.718002.10610HepG2DDX6
RPS6KA1ENSG00000117676.9406.11590542.68690-0.418202.665101.70040HepG2DHX30
RPS6KA1ENSG00000117676.9515.80600647.39680-0.327802.443801.80070HepG2DKC1
RPS6KA1ENSG00000117676.9703.49180910.95500-0.372803.818402.86430HepG2EIF4G1
RPS6KA1ENSG00000117676.91038.54120717.261400.533902.297201.59270HepG2FIP1L1
RPS6KA1ENSG00000117676.9338.07990483.38580-0.515803.558002.67180HepG2FUBP3
RPS6KA1ENSG00000117676.9935.06700666.899500.487503.566702.78760HepG2FXR1
RPS6KA1ENSG00000117676.9405.13460568.06900-0.487703.310202.61140HepG2HNRNPA1
RPS6KA1ENSG00000117676.91020.59190848.589400.266202.293301.43380HepG2HNRNPA2B1
RPS6KA1ENSG00000117676.9440.83320631.84790-0.519303.796802.99550HepG2HNRNPC
RPS6KA1ENSG00000117676.9686.45410841.08500-0.293102.817402.13850HepG2HNRNPL
RPS6KA1ENSG00000117676.9254.29210469.15340-0.883607.085806.13140HepG2HNRNPLL
RPS6KA1ENSG00000117676.9900.67440627.672300.520907.163006.22350HepG2HNRNPU
RPS6KA1ENSG00000117676.91087.21210670.841100.696506.102205.19240HepG2MATR3
RPS6KA1ENSG00000117676.9233.47440416.02990-0.833406.118405.03200HepG2NSUN2
RPS6KA1ENSG00000117676.9310.54860611.38580-0.977309.732308.39680HepG2PABPC4
RPS6KA1ENSG00000117676.9421.75480659.32400-0.644607.736406.80240HepG2PCBP1
RPS6KA1ENSG00000117676.9454.80320559.83770-0.299801.961101.33220HepG2PPIL4
RPS6KA1ENSG00000117676.91143.02390874.012600.387003.323702.67910HepG2PUF60
RPS6KA1ENSG00000117676.9699.85200927.12850-0.405703.497302.74730HepG2PUM2
RPS6KA1ENSG00000117676.9905.58950714.224200.342402.806601.94490HepG2RBM15
RPS6KA1ENSG00000117676.9358.12630659.41840-0.880708.223707.11050HepG2RBM25
RPS6KA1ENSG00000117676.91388.85850838.332800.728209.923708.76660HepG2RPLP0
RPS6KA1ENSG00000117676.9584.41360459.042200.348302.006601.47510HepG2RPS19
RPS6KA1ENSG00000117676.9742.49110558.984000.409504.304103.53270HepG2SAFB2
RPS6KA1ENSG00000117676.9338.65310460.63120-0.443802.344901.47580HepG2SERBP1
RPS6KA1ENSG00000117676.9233.96310464.34070-0.988909.155107.94510HepG2SF3B1
RPS6KA1ENSG00000117676.9498.19160698.44900-0.487504.685403.94670HepG2SF3B4
RPS6KA1ENSG00000117676.9787.36740651.893500.272302.419301.81240HepG2SMN1
RPS6KA1ENSG00000117676.9331.57680516.67070-0.639903.205202.36220HepG2SNRNP70
RPS6KA1ENSG00000117676.91300.326601026.059700.341704.106303.53100HepG2SRFBP1
RPS6KA1ENSG00000117676.9937.40610729.059500.362503.814703.28180HepG2SRSF1
RPS6KA1ENSG00000117676.91290.31640862.970300.5802010.270809.16760HepG2SRSF5
RPS6KA1ENSG00000117676.9707.80880890.87020-0.331903.257702.71200HepG2SSB
RPS6KA1ENSG00000117676.9280.09620622.82550-1.1529012.2891011.03220HepG2SUPV3L1
RPS6KA1ENSG00000117676.9880.08480655.390300.425204.476503.78930HepG2TAF15
RPS6KA1ENSG00000117676.9302.49680457.40980-0.596603.992803.14140HepG2TARDBP
RPS6KA1ENSG00000117676.9469.21860609.99040-0.378502.677502.18390HepG2TIAL1
RPS6KA1ENSG00000117676.9688.58090853.88710-0.310402.086901.33750HepG2TUFM
RPS6KA1ENSG00000117676.9671.75600903.83510-0.428102.311401.55220HepG2UBE2L3
RPS6KA1ENSG00000117676.9750.52320576.134500.381403.838403.03620HepG2UPF1
RPS6KA1ENSG00000117676.9344.27440491.94740-0.514904.742503.90210HepG2ZC3H8
RPS6KA1ENSG00000117676.91025.80420633.637600.6949014.4238013.41720HepG2ZNF622
RPS6KA1ENSG00000117676.91252.118401048.606200.255802.581902.02940K562AGGF1
RPS6KA1ENSG00000117676.91411.527701152.298300.292602.299401.41500K562AKAP8
RPS6KA1ENSG00000117676.91607.589401091.131800.559006.791105.73110K562AKAP8L
RPS6KA1ENSG00000117676.9920.487601892.29290-1.0397018.8130017.45160K562AQR
RPS6KA1ENSG00000117676.9740.752201062.82190-0.520807.571805.38290K562DDX27
RPS6KA1ENSG00000117676.9933.210701737.59150-0.8968025.3067023.52940K562DDX47
RPS6KA1ENSG00000117676.9528.37860925.14850-0.808105.298103.86860K562EIF3A
RPS6KA1ENSG00000117676.9827.894201133.53260-0.453303.122702.02000K562EIF3D
RPS6KA1ENSG00000117676.9782.120101125.99100-0.525704.358602.89010K562FKBP4
RPS6KA1ENSG00000117676.9237.21300637.00560-1.4251013.7820011.94640K562G3BP2
RPS6KA1ENSG00000117676.91051.674201514.39440-0.526107.924306.07820K562GLRX3
RPS6KA1ENSG00000117676.91384.179001867.88290-0.432404.783703.79000K562GRSF1
RPS6KA1ENSG00000117676.91164.925001723.32000-0.565007.864806.13370K562HNRNPA1
RPS6KA1ENSG00000117676.9826.571701296.75250-0.649708.502407.50710K562HNRNPC
RPS6KA1ENSG00000117676.9918.609501158.05130-0.334202.570701.47730K562HNRNPF
RPS6KA1ENSG00000117676.91595.193501908.56620-0.258802.520301.66690K562HNRNPU
RPS6KA1ENSG00000117676.91116.320301411.54590-0.338502.510101.74890K562HSPD1
RPS6KA1ENSG00000117676.91721.457901297.179000.408204.866803.59620K562MBNL1
RPS6KA1ENSG00000117676.91005.692201592.19490-0.6628014.8346013.14180K562MTPAP
RPS6KA1ENSG00000117676.92013.852302604.73810-0.371203.312601.66400K562NOL12
RPS6KA1ENSG00000117676.91474.478401769.03410-0.262803.973903.09890K562NSUN2
RPS6KA1ENSG00000117676.9944.880101362.48380-0.528004.531803.46960K562PCBP3
RPS6KA1ENSG00000117676.9801.548101045.09310-0.382803.336502.45230K562POLR2G
RPS6KA1ENSG00000117676.9727.454801030.39760-0.502304.262203.33320K562PRPF8
RPS6KA1ENSG00000117676.91461.494001002.447300.543802.636101.98540K562PTBP1
RPS6KA1ENSG00000117676.91782.445702598.25100-0.543706.265705.04180K562PUF60
RPS6KA1ENSG00000117676.92229.616502707.83320-0.280303.221602.18590K562PUM2
RPS6KA1ENSG00000117676.91537.264901082.035500.506502.156801.66540K562PUS1
RPS6KA1ENSG00000117676.91431.492601054.336800.441105.721304.89480K562RBM15
RPS6KA1ENSG00000117676.9696.824701049.44100-0.590804.756503.68340K562RPS19
RPS6KA1ENSG00000117676.9707.89600962.71620-0.443603.490701.84850K562SDAD1
RPS6KA1ENSG00000117676.91391.358001745.64080-0.327303.904102.94470K562SF3A3
RPS6KA1ENSG00000117676.9399.43740673.96690-0.754706.015304.54790K562SF3B1
RPS6KA1ENSG00000117676.9423.13530596.31010-0.494903.754101.82650K562SND1
RPS6KA1ENSG00000117676.91494.69540982.861500.604703.088202.34450K562SRSF1
RPS6KA1ENSG00000117676.9948.442201189.59390-0.326802.904001.34560K562SRSF9
RPS6KA1ENSG00000117676.9566.43820997.40640-0.816308.657306.81560K562SUPV3L1
RPS6KA1ENSG00000117676.9687.240601118.30360-0.702407.126105.56860K562TIAL1
RPS6KA1ENSG00000117676.9688.49630990.54480-0.524804.114801.93200K562TRNAU1AP
RPS6KA1ENSG00000117676.9333.76030617.32410-0.887208.011105.99540K562U2AF1
RPS6KA1ENSG00000117676.9315.16250637.60770-1.0166014.4809012.62270K562U2AF2
RPS6KA1ENSG00000117676.91464.265101875.74730-0.357305.564404.58560K562UPF1
RPS6KA1ENSG00000117676.91232.104501605.01290-0.381503.835902.80020K562WDR3
RPS6KA1ENSG00000117676.91002.513301669.06040-0.7354020.1515018.18720K562WDR43
RPS6KA1ENSG00000117676.91605.595302131.62720-0.408804.206103.10430K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RPS6KA1 is not available on ENCORE database.





2 RBPs can affect the splicing of RPS6KA1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERPS6KA1ENSG00000117676.9chr1+268820272688211626881641268817122688314426883209-0.113000.008810.08252excludedHepG2U2AF2
SERPS6KA1ENSG00000117676.9chr1+268879952688815426887535268876252689793926898101-0.056000.001360.01578excludedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RPS6KA1 is not avaliable on ENCORE database.