TNRC6B

General Information

Gene Name       : TNRC6B
Gene ID             : ENSG00000100354.20
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TNRC6B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TNRC6BENSG00000100354.204.807.216.00ENCSR000AEF
HepG2TNRC6BENSG00000100354.205.435.065.24ENCSR985KAT
K562TNRC6BENSG00000100354.204.203.583.89ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TNRC6B is not avaliable on ENCORE database.



Proteins bound to RNA
  • TNRC6B RNA is bound by 39 proteins.  







eCLIP assay for TNRC6B is not avaliable on ENCORE database.





39 proteins are bound to TNRC6B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr224071972840719787+3'-UTR3.754965.78219HepG2FAM120A
chr224071972340719777+3'-UTR3.151513.00221HepG2CSTF2T
chr224073055440730626+3'-UTR3.497704.53300K562LIN28B
chr224072454240724588+3'-UTR3.432273.63497HepG2TIA1
chr224071992940720008+3'-UTR3.487673.66977HepG2PCBP2
chr224052176340521825+3'-UTR,5'-UTR,CDS,intron-Proximal3.500714.65237HepG2U2AF2
chr224072351540723609+3'-UTR3.407079.14792HepG2PCBP2
chr224072454640724561+3'-UTR3.3925911.85449K562TIA1
chr224072060140720640+3'-UTR4.356324.36811K562FAM120A
chr224071966140719700+3'-UTR3.059073.31456K562TIA1
chr224072456140724604+3'-UTR3.4922812.01870K562TIA1
chr224072361240723702+3'-UTR4.341465.21253K562LIN28B
chr224071965340719696+3'-UTR5.3527510.27311K562PABPC4
chr224044152440441585+5'-UTR,intron-Distal3.922543.80512K562CSTF2T
chr224044083840440929+5'-UTR3.198934.00376HepG2NCBP2
chr224044138940441486+5'-UTR,intron-Distal3.575579.05327HepG2CSTF2T
chr224066090140660928+CDS,intron-Distal3.754074.76554HepG2BCLAF1
chr224066110740661127+CDS,intron-Distal4.715074.37348HepG2BCLAF1
chr224069650540696592+CDS,intron-Proximal3.455875.63425HepG2BCLAF1
chr224064718740647205+CDS,intron-Proximal4.632704.66217K562ZNF800
chr224065783540657907+CDS,intron-Proximal3.488615.91739K562UCHL5
chr224070456340704624+CDS3.176663.55800HepG2BCLAF1
chr224065784040657918+CDS3.174045.02671K562PUM1
chr224065783540657911+CDS,intron-Proximal3.999724.96634HepG2PPIG
chr224070451040704588+CDS,intron-Proximal3.410253.99381K562BUD13
chr224066095940661002+CDS,intron-Distal3.674033.69481K562UCHL5
chr224064717740647208+CDS,intron-Proximal3.240683.75245K562BUD13
chr224055213740552183+CDS3.704304.76554HepG2BCLAF1
chr224069691340696948+CDS,intron-Proximal3.844364.76554HepG2BCLAF1
chr224071715140717223+CDS4.010013.74511K562IGF2BP1
chr224066185340661925+CDS,intron-Distal4.936845.44793K562ZNF622
chr224066258740662614+CDS,intron-Distal3.387073.36945K562ZNF622
chr224066256040662674+CDS,intron-Distal4.473959.66045K562UCHL5
chr224067706240677229+CDS,intron-Distal,intron-Proximal4.0507510.53796HepG2QKI
chr224067600640676119+CDS3.885597.83567HepG2BCLAF1
chr224066216740662242+CDS,intron-Distal3.597047.10975K562UCHL5
chr224065783940657940+CDS5.019486.09052HepG2ZNF800
chr224064201640642063+CDS,intron-Proximal3.964128.49795HepG2BCLAF1
chr224071890740718989+CDS3.325375.40646K562RBM15
chr224064201240642109+CDS,intron-Proximal5.256106.18406HepG2TRA2A
chr224066258840662672+CDS,intron-Distal3.944398.52328HepG2HLTF
chr224071704240717138+CDS,intron-Proximal3.145206.98894K562SF3B4
chr224065783340657909+CDS,intron-Proximal4.1857612.07231HepG2BCLAF1
chr224066188940661913+CDS,intron-Distal3.982174.17155HepG2BCLAF1
chr224070452240704643+CDS4.239254.67299K562DDX24
chr224069644640696510+CDS,intron-Proximal3.177914.14020K562BUD13
chr224067611940676146+CDS4.187843.71570HepG2BCLAF1
chr224055211740552185+CDS,intron-Proximal3.572654.74268K562UCHL5
chr224064718240647204+CDS,intron-Proximal4.118103.42472HepG2FXR2
chr224071888740718988+CDS4.464974.34093HepG2RBM15
chr224069645540696505+CDS,intron-Proximal3.365155.15776HepG2BCLAF1
chr224064718240647206+CDS,intron-Proximal3.686454.13746HepG2PPIG
chr224066128140661373+CDS,intron-Distal4.150356.14226K562ZNF622
chr224064202240642107+CDS,intron-Proximal5.218927.45503HepG2FXR2
chr224066171740661798+CDS,intron-Distal3.200427.50579HepG2HLTF
chr224065783040657942+CDS,intron-Proximal3.413037.07421HepG2BUD13
chr224071903840719084+CDS3.270963.34231K562RBM15
chr224065805940658119+CDS4.573525.30668HepG2RBFOX2
chr224065783740657918+CDS4.538895.59408HepG2GRWD1
chr224066084740660957+CDS,intron-Distal3.516385.28199HepG2GRWD1
chr224071709440717216+CDS4.523385.85983HepG2GRWD1
chr224066132140661358+CDS,intron-Distal3.476063.95937K562UCHL5
chr224066253740662653+CDS,intron-Distal5.4035515.52964HepG2BCLAF1
chr224066248040662507+CDS,intron-Distal3.687844.51739HepG2BCLAF1
chr224064718040647205+CDS,intron-Proximal4.054106.23296HepG2BCLAF1
chr224066106540661118+CDS,intron-Distal3.181354.84290HepG2HLTF
chr224071709640717223+CDS3.215673.47314HepG2G3BP1
chr224066173040661777+CDS,intron-Distal3.073877.17439HepG2BCLAF1
chr224066130540661386+CDS,intron-Distal3.272678.43208HepG2BCLAF1
chr224067312540673156+CDS,intron-Proximal4.291073.89826HepG2BCLAF1
chr224068164640681696+CDS,intron-Proximal3.673844.17155HepG2BCLAF1
chr224066168940661775+CDS,intron-Distal3.556004.78418HepG2EIF3H
chr224067400240674052+CDS,intron-Proximal3.588875.56491HepG2BCLAF1
chr224064206340642107+CDS,intron-Proximal3.899056.97808HepG2BCLAF1
chr224064204240642107+CDS,intron-Proximal4.840746.96356K562UCHL5
chr224066214640662234+CDS,intron-Distal3.337604.27261HepG2GRWD1
chr224058372440583844+intron-Distal3.600624.69053HepG2SFPQ
chr224066872840668847+intron-Distal3.043583.99165HepG2PTBP1
chr224066872040668828+intron-Distal3.783675.93532K562PTBP1
chr224058615840586283+intron-Distal3.961543.80512K562CSTF2T
chr224044168540441741+intron-Distal,intron-Proximal6.4137016.92618HepG2XPO5
chr224059329740593358+intron-Distal3.407234.41834HepG2HNRNPC
chr224070188440701969+intron-Distal5.724579.44534K562PTBP1
chr224048190640481958+intron-Distal3.435863.68481HepG2HNRNPM
chr224059573740595814+intron-Distal3.225113.68839K562KHSRP
chr224049364140493749+intron-Distal3.145654.89630HepG2HNRNPL
chr224051560040515729+intron-Distal3.091203.82777K562HNRNPL
chr224044127340441336+intron-Distal3.005115.43093HepG2CSTF2T
chr224069666340696747+intron-Distal,intron-Proximal4.073683.31283K562PRPF8
chr224057528740575375+intron-Distal3.473573.38316HepG2SFPQ
chr224044126040441344+intron-Distal4.406334.48935K562CSTF2T
chr224062072440620790+intron-Distal4.185563.18981K562PTBP1
chr224058599940586062+intron-Distal3.283095.79202HepG2U2AF2
chr224044127940441346+intron-Distal4.458703.67126HepG2NKRF
chr224044118240441242+intron-Distal3.457764.60046HepG2CSTF2T
chr224047651840476590+intron-Distal4.034213.71677HepG2HNRNPL
chr224045494140455036+intron-Distal4.297873.74583HepG2PTBP1
chr224044117740441254+intron-Distal4.085034.10323HepG2PRPF4
chr224070187540701967+intron-Distal5.708899.85976HepG2PTBP1
chr224044139440441442+intron-Distal3.310163.16890HepG2XRN2
chr224063818740638276+intron-Distal4.228644.39969K562TARDBP
chr224046168840461744+intron-Distal4.372173.04182K562HNRNPM
chr224055193340552009+intron-Distal4.242863.79000HepG2U2AF2
chr224045206340452132+intron-Distal3.991384.19039HepG2PTBP1
chr224068108440681163+intron-Distal3.830624.79983HepG2U2AF2
chr224057876040578806+intron-Distal4.021413.62366HepG2HNRNPM
chr224046167940461772+intron-Distal5.159885.37406HepG2HNRNPM
chr224044117240441234+intron-Distal3.784523.46348HepG2XRN2
chr224046603940466106+intron-Distal4.538785.41654K562KHSRP
chr224044161740441690+intron-Distal,intron-Proximal3.898083.17740K562CSTF2T
chr224044117040441251+intron-Distal4.565225.92397HepG2FAM120A
chr224057854340578669+intron-Distal3.533364.50064HepG2SFPQ
chr224071704340717077+intron-Proximal4.757275.80027HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TNRC6B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TNRC6B is not available on ENCORE database.

  • 95 RBPs can affect the levels of TNRC6B.  








The Knockdown/knockout RNA-Seq assay for TNRC6B is not available on ENCORE database.





95 RBPs can affect the gene expression of TNRC6B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TNRC6BENSG00000100354.161252.04020968.315300.370604.462303.72600HepG2ACO1
TNRC6BENSG00000100354.161590.930801034.543800.620805.390104.67760HepG2AKAP1
TNRC6BENSG00000100354.161161.42280972.957500.255302.400801.68040HepG2AKAP8L
TNRC6BENSG00000100354.161202.98750968.216500.313103.930903.16460HepG2CKAP4
TNRC6BENSG00000100354.161584.56160982.157400.690008.676107.51680HepG2CPSF6
TNRC6BENSG00000100354.16725.34200907.69810-0.323602.858801.82300HepG2YBX3
TNRC6BENSG00000100354.16747.225901071.74800-0.520308.288807.11070HepG2DAZAP1
TNRC6BENSG00000100354.16500.77650908.97210-0.8601014.3626012.08630HepG2DDX1
TNRC6BENSG00000100354.16576.23150767.28480-0.413102.200001.50340HepG2DDX55
TNRC6BENSG00000100354.161693.541701115.314200.602503.146602.10420HepG2DDX59
TNRC6BENSG00000100354.16630.48050891.30220-0.499504.231003.37660HepG2DNAJC21
TNRC6BENSG00000100354.16630.74340883.41630-0.486007.031706.05890HepG2DNAJC2
TNRC6BENSG00000100354.161773.45760904.450000.9714012.8253011.47490HepG2EIF4A3
TNRC6BENSG00000100354.161279.56950880.561500.539103.406602.64600HepG2EIF4B
TNRC6BENSG00000100354.16796.272701057.43900-0.409204.471303.44820HepG2EIF4G1
TNRC6BENSG00000100354.161873.619201642.526400.189801.869901.35500HepG2ETF1
TNRC6BENSG00000100354.161200.75090912.476800.396002.812702.11450HepG2FXR1
TNRC6BENSG00000100354.161558.89990846.495700.8809011.091909.80270HepG2G3BP1
TNRC6BENSG00000100354.161249.95720898.611900.476003.919102.84790HepG2G3BP2
TNRC6BENSG00000100354.16619.63350899.84090-0.538305.018404.18270HepG2HNRNPA1
TNRC6BENSG00000100354.16805.68520985.01960-0.289902.445801.55940HepG2HNRNPA2B1
TNRC6BENSG00000100354.161226.13280857.061000.516504.784403.88670HepG2HNRNPK
TNRC6BENSG00000100354.16635.90780976.24740-0.6184010.599209.35930HepG2HNRNPL
TNRC6BENSG00000100354.161473.495601062.474900.471703.069102.41040HepG2HNRNPLL
TNRC6BENSG00000100354.16843.61460994.28460-0.237102.084301.54990HepG2HNRNPU
TNRC6BENSG00000100354.161265.55700865.447800.548203.762202.57420HepG2KHSRP
TNRC6BENSG00000100354.161240.11980912.795000.442003.287502.57300HepG2MAGOH
TNRC6BENSG00000100354.161411.54770917.916100.620705.476704.61390HepG2MATR3
TNRC6BENSG00000100354.161258.34650939.548100.421402.932902.28220HepG2NCBP2
TNRC6BENSG00000100354.161175.45130836.774600.490203.844503.00490HepG2PABPC4
TNRC6BENSG00000100354.161351.45220850.183900.668609.132408.13390HepG2PCBP1
TNRC6BENSG00000100354.161448.118101039.049800.478802.710401.68190HepG2PCBP2
TNRC6BENSG00000100354.16641.90380886.82330-0.466305.169304.19010HepG2PPIL4
TNRC6BENSG00000100354.161648.075701205.387600.451207.283506.09910HepG2PRPF4
TNRC6BENSG00000100354.161083.80520865.179500.324901.791701.33240HepG2PTBP1
TNRC6BENSG00000100354.16900.598801076.98990-0.258002.463201.89650HepG2PUM1
TNRC6BENSG00000100354.161278.133701076.181300.248002.030401.44960HepG2PUM2
TNRC6BENSG00000100354.16849.76650986.30820-0.215001.827701.30480HepG2PUS1
TNRC6BENSG00000100354.161631.80880936.828400.8005016.5426015.19920HepG2QKI
TNRC6BENSG00000100354.161515.052601002.713200.595403.194102.44020HepG2RAVER1
TNRC6BENSG00000100354.161795.995901372.851400.387505.279004.62070HepG2RBM22
TNRC6BENSG00000100354.161186.61900850.300900.480705.273404.37090HepG2RBM25
TNRC6BENSG00000100354.161248.15050962.790600.374403.338502.75590HepG2NELFE
TNRC6BENSG00000100354.161075.48060896.837600.262001.912401.38680HepG2RECQL
TNRC6BENSG00000100354.16627.47080885.45740-0.496906.748105.80750HepG2SAFB2
TNRC6BENSG00000100354.161654.045601051.628800.653308.234107.07730HepG2SF3B1
TNRC6BENSG00000100354.161381.15920900.610100.6168011.3237010.25280HepG2SF3B4
TNRC6BENSG00000100354.16769.077201032.59800-0.425106.128805.23090HepG2SMN1
TNRC6BENSG00000100354.162441.100301170.125601.0608011.157609.60290HepG2SNRNP70
TNRC6BENSG00000100354.161784.426901550.591000.202502.416901.93770HepG2SRFBP1
TNRC6BENSG00000100354.161285.19030940.104600.451005.628105.01330HepG2SRSF1
TNRC6BENSG00000100354.161710.322901131.589000.595804.802503.45060HepG2SRSF3
TNRC6BENSG00000100354.161565.47290764.879101.0332034.8310033.29700HepG2SRSF9
TNRC6BENSG00000100354.161693.112201346.290200.330604.706704.07330HepG2SSB
TNRC6BENSG00000100354.161234.44830763.821300.692506.329905.36810HepG2SUPV3L1
TNRC6BENSG00000100354.161543.78760845.176400.8690017.1861015.95920HepG2TAF15
TNRC6BENSG00000100354.16590.31380974.76850-0.7236012.9986011.90290HepG2TRIM56
TNRC6BENSG00000100354.161437.328901120.585900.359002.881302.24080HepG2U2AF1
TNRC6BENSG00000100354.161888.89800945.120900.998903.182302.12270HepG2U2AF2
TNRC6BENSG00000100354.16307.23170451.21350-0.554503.406402.56870HepG2UCHL5
TNRC6BENSG00000100354.16567.13530805.70930-0.506602.913201.78210HepG2XPO5
TNRC6BENSG00000100354.16572.16640751.89830-0.394102.242701.58420HepG2XRN2
TNRC6BENSG00000100354.161789.161101189.536700.5888014.6586013.31080HepG2ZC3H8
TNRC6BENSG00000100354.16864.849501517.59680-0.8113024.9530023.72330HepG2ZNF622
TNRC6BENSG00000100354.161393.190701024.779200.443001.796701.30360K562AQR
TNRC6BENSG00000100354.16949.16460720.558000.397402.197501.42670K562BOP1
TNRC6BENSG00000100354.161495.251501830.61940-0.291902.477601.37500K562CCDC124
TNRC6BENSG00000100354.161707.611801172.534900.542202.804401.73320K562CNOT7
TNRC6BENSG00000100354.161197.457301434.44800-0.260502.718501.62170K562CPEB4
TNRC6BENSG00000100354.161462.13310766.113000.9323016.7771014.82300K562CPSF6
TNRC6BENSG00000100354.162354.498401861.772100.338603.840302.68130K562CELF1
TNRC6BENSG00000100354.161096.09260699.885600.647106.772805.29540K562EFTUD2
TNRC6BENSG00000100354.161482.74260913.965500.698009.537508.00340K562EIF4A3
TNRC6BENSG00000100354.161201.50870779.592600.624006.544205.20800K562FMR1
TNRC6BENSG00000100354.16892.67600660.814400.433802.969602.02120K562FTO
TNRC6BENSG00000100354.161265.887701037.253100.287302.692001.56520K562GLRX3
TNRC6BENSG00000100354.16933.56160731.411900.352002.453601.70370K562GPKOW
TNRC6BENSG00000100354.16911.879301131.14680-0.310902.332801.63620K562GRSF1
TNRC6BENSG00000100354.161126.81510703.044400.680508.641907.63800K562HNRNPC
TNRC6BENSG00000100354.161081.651001341.36980-0.310502.505901.50470K562HNRNPL
TNRC6BENSG00000100354.16618.99810849.28320-0.456302.991902.02000K562HNRNPM
TNRC6BENSG00000100354.16874.604901399.98290-0.678708.447507.07240K562HSPD1
TNRC6BENSG00000100354.161639.851901071.000800.614503.319801.74100K562ILF2
TNRC6BENSG00000100354.161163.79460624.632800.897708.651706.88510K562KRR1
TNRC6BENSG00000100354.16892.29220713.955500.321602.146601.37480K562METAP2
TNRC6BENSG00000100354.161480.664201211.638000.289204.239803.33770K562NSUN2
TNRC6BENSG00000100354.161778.756601126.468400.659004.357202.78200K562PABPC1
TNRC6BENSG00000100354.161243.19920971.428100.355802.792301.80780K562PCBP2
TNRC6BENSG00000100354.161940.374701318.817400.557005.407604.23840K562PCBP3
TNRC6BENSG00000100354.161364.966901011.558800.432204.747103.69800K562POLR2G
TNRC6BENSG00000100354.16815.536201172.14170-0.523305.063203.89830K562PPIG
TNRC6BENSG00000100354.16624.390701060.78450-0.7646011.4794010.18660K562PTBP1
TNRC6BENSG00000100354.162100.127201652.135800.346003.172802.30080K562PUF60
TNRC6BENSG00000100354.161493.22370808.879600.884303.742902.27760K562SF1
TNRC6BENSG00000100354.161432.201801195.662500.260302.662001.86190K562SF3A3
TNRC6BENSG00000100354.161142.69120695.735300.715706.807205.24060K562SF3B1
TNRC6BENSG00000100354.161075.09000890.702800.271302.086101.34560K562SF3B4
TNRC6BENSG00000100354.161495.77360929.143500.686802.742001.51870K562SNRNP200
TNRC6BENSG00000100354.161597.495501239.194600.366302.668001.44520K562STAU1
TNRC6BENSG00000100354.161212.15900659.400700.8783010.318908.29850K562SUPV3L1
TNRC6BENSG00000100354.16784.956201015.21760-0.371103.224502.33160K562TIA1
TNRC6BENSG00000100354.161201.87050857.505300.487005.741204.58440K562U2AF2
TNRC6BENSG00000100354.16926.35600697.905400.408402.851801.81470K562UCHL5
TNRC6BENSG00000100354.161437.573801099.295500.387003.821002.78790K562WDR3
TNRC6BENSG00000100354.161877.578801093.313100.780103.527101.65090K562YTHDC2
TNRC6BENSG00000100354.161648.092901154.172900.513803.931202.87010K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TNRC6B is not available on ENCORE database.





2 RBPs can affect the splicing of TNRC6B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETNRC6BENSG00000100354.16chr22+406730804067315540669428406696044067400240674048-0.465000.000000.00011excludedK562SRSF1
SETNRC6BENSG00000100354.16chr22+406606914066304040657835406581774066942840669604-0.518000.000140.00586excludedK562RBM15

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TNRC6B is not avaliable on ENCORE database.