LYL1

General Information

Gene Name       : LYL1
Gene ID             : ENSG00000104903.4
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: LYL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LYL1ENSG00000104903.40.821.621.22ENCSR000AEF
HepG2LYL1ENSG00000104903.40.610.170.39ENCSR985KAT
K562LYL1ENSG00000104903.451.6212.0031.81ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LYL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LYL1 RNA is bound by 12 proteins.  







eCLIP assay for LYL1 is not avaliable on ENCORE database.





12 proteins are bound to LYL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr191320987313209916-3'-UTR,intron-Distal3.691616.15559K562PABPC4
chr191321001213210087-3'-UTR,intron-Distal4.7555221.10866K562PABPC4
chr191320992113209951-3'-UTR,intron-Distal3.6850515.07095K562YBX3
chr191320988313209921-3'-UTR,intron-Distal3.368818.87920K562YBX3
chr191321001413210072-3'-UTR,intron-Distal3.065034.76726K562DDX6
chr191320995113209976-3'-UTR,intron-Distal3.2502413.75751K562YBX3
chr191321336013213448-5'-UTR,intron-Distal3.870013.44687K562SRSF1
chr191321197013212066-5'-UTR,CDS,intron-Distal,intron-Proximal4.4094031.87047K562AQR
chr191321347213213558-5'-UTR,intron-Distal3.6237010.74468K562DDX3X
chr191321335813213375-5'-UTR,intron-Distal3.128597.19943K562YBX3
chr191321324113213373-5'-UTR,intron-Distal3.329865.81466K562BUD13
chr191321337713213472-5'-UTR,intron-Distal3.7290415.06047K562DDX3X
chr191321046613210480-CDS,intron-Distal3.1721310.23502K562YBX3
chr191321050913210553-CDS,intron-Distal4.962488.03975K562BUD13
chr191321048013210504-CDS,intron-Distal4.9968817.55690K562YBX3
chr191321155013211607-CDS,intron-Distal,intron-Proximal4.006434.22551K562SF3B4
chr191321050413210517-CDS,intron-Distal4.0531316.50437K562YBX3
chr191321035213210395-CDS,intron-Distal4.268933.67707K562METAP2
chr191321231113212389-intron-Distal3.504656.39945K562GTF2F1
chr191321313713213188-intron-Distal3.584707.97261K562PRPF8
chr191321315713213281-intron-Distal3.126817.19624K562EFTUD2
chr191321139213211427-intron-Distal,intron-Proximal5.7935510.04245K562AQR
chr191321142713211470-intron-Distal,intron-Proximal6.2663313.68711K562AQR
chr191321247813212576-intron-Distal3.510797.78725K562GTF2F1
chr191321318913213283-intron-Distal3.6752714.53880K562AQR
chr191321328313213345-intron-Distal5.4075137.72981K562AQR
chr191321261813212709-intron-Distal3.551204.24485K562GTF2F1
chr191321156413211605-intron-Distal,intron-Proximal3.664683.75245K562BUD13
chr191321134713211442-intron-Distal,intron-Proximal3.825206.41318K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LYL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LYL1 is not available on ENCORE database.

  • 69 RBPs can affect the levels of LYL1.  








The Knockdown/knockout RNA-Seq assay for LYL1 is not available on ENCORE database.





69 RBPs can affect the gene expression of LYL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LYL1ENSG00000104903.421.511204.711302.190802.755602.14970HepG2HNRNPU
LYL1ENSG00000104903.453.6071021.860901.294002.640802.13200HepG2RBM22
LYL1ENSG00000104903.46.9885021.43550-1.616901.846401.40590HepG2SSB
LYL1ENSG00000104903.419.197204.618902.055202.350801.82280HepG2TRIM56
LYL1ENSG00000104903.452.0673019.527801.414802.980902.32940HepG2U2AF1
LYL1ENSG00000104903.42114.065901455.704700.538203.191202.11940K562AKAP8
LYL1ENSG00000104903.42525.757301768.345800.514205.634703.77340K562APOBEC3C
LYL1ENSG00000104903.41267.67340602.900501.072109.734407.91930K562BCLAF1
LYL1ENSG00000104903.41465.25020887.240900.723603.792502.51790K562CCAR1
LYL1ENSG00000104903.41926.810001583.212400.283302.593501.46340K562CCDC124
LYL1ENSG00000104903.42059.953001622.593200.344204.337202.93160K562CPEB4
LYL1ENSG00000104903.4928.58910736.164800.334902.093501.40260K562CPSF6
LYL1ENSG00000104903.41120.89800457.390201.293103.181302.03790K562CSTF2
LYL1ENSG00000104903.42523.608201679.094600.5877013.9670012.61470K562DDX47
LYL1ENSG00000104903.4795.75210496.317200.681003.993701.96060K562DDX51
LYL1ENSG00000104903.4925.09450459.181501.0104010.539308.65160K562EFTUD2
LYL1ENSG00000104903.41882.390501147.503100.714005.956904.96110K562EIF2S2
LYL1ENSG00000104903.4706.49960491.412000.523702.565601.57180K562EIF3D
LYL1ENSG00000104903.4398.49550280.706100.505403.533702.64110K562EIF3G
LYL1ENSG00000104903.41102.45510833.750600.402904.435202.91260K562EIF4B
LYL1ENSG00000104903.41397.07780949.496400.557102.585101.36450K562EXOSC5
LYL1ENSG00000104903.41428.156201051.015700.442304.206403.14580K562FIP1L1
LYL1ENSG00000104903.4566.60500749.10760-0.402802.676301.83630K562FMR1
LYL1ENSG00000104903.439.37930168.28280-2.0954013.0059011.22540K562G3BP2
LYL1ENSG00000104903.4990.28590702.824200.494604.489703.48290K562GPKOW
LYL1ENSG00000104903.42270.080401528.965700.570102.147901.47660K562GRSF1
LYL1ENSG00000104903.41115.08760683.892200.705204.346603.61520K562HNRNPC
LYL1ENSG00000104903.42706.516401589.967100.767306.127904.78660K562HNRNPU
LYL1ENSG00000104903.41223.238801462.94750-0.258202.017601.32200K562KIF1C
LYL1ENSG00000104903.4791.04380348.540501.1823015.0837013.01170K562MAGOH
LYL1ENSG00000104903.4563.06630347.797200.695004.803103.55150K562MATR3
LYL1ENSG00000104903.4871.17140686.048300.344502.519301.68750K562METAP2
LYL1ENSG00000104903.4684.032301148.72480-0.747905.703104.27510K562NAA15
LYL1ENSG00000104903.4498.84360924.52150-0.8901013.8557011.24590K562NCBP2
LYL1ENSG00000104903.4963.54560453.011301.088703.446401.97450K562NONO
LYL1ENSG00000104903.42110.241701887.054100.161202.026401.37620K562NSUN2
LYL1ENSG00000104903.4564.11990310.071300.863308.756606.98410K562PCBP2
LYL1ENSG00000104903.4525.29320926.28260-0.818302.288501.55990K562POLR2G
LYL1ENSG00000104903.41967.493601193.239900.7214010.391708.51120K562PPIG
LYL1ENSG00000104903.4811.15940446.842300.860103.281902.46330K562PRPF8
LYL1ENSG00000104903.4794.98960338.646601.2311018.8006017.14990K562PTBP1
LYL1ENSG00000104903.41566.990302326.61030-0.570203.924202.63210K562PUM1
LYL1ENSG00000104903.43031.165502278.811900.411503.752002.63190K562PUM2
LYL1ENSG00000104903.41001.194401367.13690-0.449403.633903.02350K562PUS1
LYL1ENSG00000104903.4830.08260324.591801.3545023.8673021.17380K562RBM22
LYL1ENSG00000104903.4971.28440559.967400.794506.706905.16150K562RCC2
LYL1ENSG00000104903.4555.99280341.611300.702602.495101.46480K562NELFE
LYL1ENSG00000104903.41319.80720825.652700.676602.535101.50060K562SAFB
LYL1ENSG00000104903.41598.156701862.20960-0.220602.146001.42020K562SF3A3
LYL1ENSG00000104903.4295.75980174.848600.758205.464204.23570K562SF3B4
LYL1ENSG00000104903.41542.328501055.180600.547503.381101.42570K562SMN1
LYL1ENSG00000104903.4458.51300985.58570-1.104006.158804.08770K562SNRNP200
LYL1ENSG00000104903.4995.05840530.788900.906504.985303.48540K562SRFBP1
LYL1ENSG00000104903.4794.45820446.425000.831506.826104.12660K562SRP68
LYL1ENSG00000104903.41521.446401907.88920-0.326503.641902.58460K562SRPK2
LYL1ENSG00000104903.4667.04730332.013301.006405.590104.59130K562SRSF1
LYL1ENSG00000104903.4875.00720349.035001.3258017.2416014.50190K562SRSF4
LYL1ENSG00000104903.4644.95590313.627601.0400013.0260010.58770K562SRSF5
LYL1ENSG00000104903.4203.25260289.55900-0.510602.579801.34900K562SSB
LYL1ENSG00000104903.4831.557901378.86720-0.729606.559904.41340K562SSRP1
LYL1ENSG00000104903.4505.071101209.47340-1.259805.786002.85440K562SUGP2
LYL1ENSG00000104903.4608.263901179.14550-0.955004.768102.71820K562SUPT6H
LYL1ENSG00000104903.473.25010165.17810-1.173104.619002.55590K562TAF15
LYL1ENSG00000104903.41007.32950335.961601.5841017.5392015.44320K562TARDBP
LYL1ENSG00000104903.4821.14860324.088001.3412025.1836022.52860K562TIA1
LYL1ENSG00000104903.4585.92090318.162900.880806.687204.81030K562TRA2A
LYL1ENSG00000104903.41109.28710627.085800.822802.660201.73640K562TRIM56
LYL1ENSG00000104903.4701.23940457.728100.615302.812201.78350K562UCHL5
LYL1ENSG00000104903.42871.672202000.892400.5211013.0380011.61660K562UPF1
LYL1ENSG00000104903.41419.248701712.08580-0.270602.190801.41230K562WDR3
LYL1ENSG00000104903.41274.085601780.47130-0.482803.397502.46910K562WDR43
LYL1ENSG00000104903.4968.52990466.332801.054303.541902.11230K562XRN2
LYL1ENSG00000104903.4461.741601160.12670-1.329108.780605.39610K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LYL1 is not available on ENCORE database.





3 RBPs can affect the splicing of LYL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELYL1ENSG00000104903.4chr19-1321200913212043132116501321186213213344132139750.353000.000080.00137includedK562AQR
SELYL1ENSG00000104903.4chr19-132116501321200913211470132115621321334413213681-0.089000.000040.00611excludedK562SUPV3L1
A3SSLYL1ENSG00000104903.4chr19-132115031321156213211503132115421321165013211862-0.093000.000280.06123shorterK562SUPV3L1
A3SSLYL1ENSG00000104903.4chr19-132115031321156213211503132115421321165013211862-0.073000.000440.00334shorterK562AQR
A3SSLYL1ENSG00000104903.4chr19-132115031321156213211503132115421321165013211862-0.162000.000000.00004shorterK562SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LYL1 is not avaliable on ENCORE database.