HEXB

General Information

Gene Name       : HEXB
Gene ID             : ENSG00000049860.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HEXB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HEXBENSG00000049860.1329.2327.2328.23ENCSR000AEF
HepG2HEXBENSG00000049860.1367.1283.6675.39ENCSR985KAT
K562HEXBENSG00000049860.1372.6571.2671.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HEXB is not avaliable on ENCORE database.



Proteins bound to RNA
  • HEXB RNA is bound by 10 proteins.  







eCLIP assay for HEXB is not avaliable on ENCORE database.





10 proteins are bound to HEXB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr57401646674016575+3'-UTR,CDS,intron-Proximal3.670073.22245K562GRWD1
chr57401646574016517+3'-UTR,CDS,intron-Proximal4.867228.09261K562LIN28B
chr57401646574016510+3'-UTR,CDS,intron-Proximal4.034793.15232HepG2LIN28B
chr57401698674017088+3'-UTR,CDS,intron-Distal,intron-Proximal3.460733.38928HepG2ZC3H11A
chr57398101473981068+5'-UTR,intron-Distal5.8134933.45257HepG2DDX3X
chr57401626574016326+5'-UTR,CDS4.184574.01886HepG2LIN28B
chr57398102473981240+5'-UTR,CDS,intron-Distal5.6688519.04529K562DDX3X
chr57398107273981151+5'-UTR,CDS,intron-Distal3.498845.92869HepG2RPS3
chr57401620174016272+5'-UTR,CDS,intron-Proximal5.8676710.47189K562SF3B4
chr57398106873981161+5'-UTR,CDS,intron-Distal7.6219895.87928HepG2DDX3X
chr57401627074016327+5'-UTR,CDS4.3175010.55855K562LIN28B
chr57401653074016573+CDS,intron-Proximal4.291224.06516HepG2SND1
chr57401133374011376+CDS,intron-Proximal4.987518.66641K562YBX3
chr57398128073981380+CDS,intron-Distal4.050386.46645HepG2SND1
chr57400937174009461+CDS,intron-Proximal3.5452010.12367K562YBX3
chr57401137174011455+CDS4.059305.48238K562IGF2BP1
chr57401462174014700+CDS,intron-Distal,intron-Proximal4.193573.18462K562IGF2BP2
chr57398117173981231+CDS,intron-Distal5.3802845.13630HepG2DDX3X
chr57398127673981341+CDS,intron-Distal4.032893.53569K562LIN28B
chr57400108674001146+CDS,intron-Proximal3.235576.91892K562SND1
chr57401417074014188+CDS3.442494.93572K562LIN28B
chr57401412074014183+CDS3.000463.68571K562IGF2BP1
chr57400108874001146+CDS,intron-Proximal3.050674.29040K562IGF2BP1
chr57401474574014799+CDS,intron-Proximal4.862378.55117K562LIN28B
chr57398123173981285+CDS,intron-Distal5.7602016.00434HepG2DDX3X
chr57401416574014189+CDS,intron-Proximal4.136474.01886HepG2LIN28B
chr57398115173981262+CDS,intron-Distal4.449078.09380HepG2RPS3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HEXB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HEXB is not available on ENCORE database.

  • 126 RBPs can affect the levels of HEXB.  








The Knockdown/knockout RNA-Seq assay for HEXB is not available on ENCORE database.





126 RBPs can affect the gene expression of HEXB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HEXBENSG00000049860.91499.703301161.275000.368903.105501.97500HepG2AATF
HEXBENSG00000049860.91159.267301634.99980-0.496103.983102.86640HepG2ABCF1
HEXBENSG00000049860.92113.996101555.725000.442309.102708.12970HepG2ACO1
HEXBENSG00000049860.94863.103202294.867001.0834017.9286016.69970HepG2AKAP1
HEXBENSG00000049860.91523.240101898.82880-0.318002.161301.46360HepG2ASCC1
HEXBENSG00000049860.92704.573602256.480300.261203.706502.93310HepG2AUH
HEXBENSG00000049860.91942.251601361.548600.512405.851605.02050HepG2BOP1
HEXBENSG00000049860.92811.984301569.007300.8416010.520809.16350HepG2CALR
HEXBENSG00000049860.91119.354901555.44640-0.474709.437408.35280HepG2CKAP4
HEXBENSG00000049860.92097.974601249.976600.7470010.855909.58920HepG2CPSF6
HEXBENSG00000049860.91155.331501480.99210-0.358304.140502.89000HepG2YBX3
HEXBENSG00000049860.94024.606602176.174200.8870032.6851030.97810HepG2CELF1
HEXBENSG00000049860.92844.911802339.924000.281805.158904.19280HepG2DAZAP1
HEXBENSG00000049860.91115.178301438.85010-0.367605.741904.59920HepG2DDX19B
HEXBENSG00000049860.93511.703601888.331800.8950012.2929011.10100HepG2DDX6
HEXBENSG00000049860.9997.114201488.42260-0.5780010.566509.41870HepG2DKC1
HEXBENSG00000049860.91804.116101454.219200.310903.611902.81450HepG2DNAJC21
HEXBENSG00000049860.91056.218901441.38390-0.448508.407207.34720HepG2DNAJC2
HEXBENSG00000049860.9989.699301210.00900-0.290002.297901.31170HepG2EIF3G
HEXBENSG00000049860.91461.726202006.27070-0.456803.398202.69130HepG2EIF4A3
HEXBENSG00000049860.91928.954202308.47650-0.259103.175702.29090HepG2EIF4G1
HEXBENSG00000049860.93119.489701650.978500.9179013.0745011.58350HepG2FIP1L1
HEXBENSG00000049860.92454.413501523.677000.687705.653004.09560HepG2FUS
HEXBENSG00000049860.91606.991302024.10330-0.332902.335901.69810HepG2FXR1
HEXBENSG00000049860.91500.971401877.72610-0.323102.038701.46460HepG2G3BP1
HEXBENSG00000049860.91813.225201485.308100.287703.727902.60660HepG2HDGF
HEXBENSG00000049860.9839.514101468.15110-0.8064012.3628011.15600HepG2HNRNPA1
HEXBENSG00000049860.92743.713102150.456000.351405.747304.48070HepG2HNRNPA2B1
HEXBENSG00000049860.92241.841201633.048600.457005.046704.13170HepG2HNRNPC
HEXBENSG00000049860.91632.110601891.73480-0.213002.060701.43550HepG2HNRNPF
HEXBENSG00000049860.92601.856001901.196200.452504.754003.85970HepG2HNRNPK
HEXBENSG00000049860.92378.802602131.492500.158301.873801.30470HepG2HNRNPL
HEXBENSG00000049860.91836.813201622.251700.179101.839701.33600HepG2HNRNPU
HEXBENSG00000049860.92302.770401714.537500.425502.919801.65090HepG2HSPD1
HEXBENSG00000049860.91506.468001862.82660-0.306302.782202.05550HepG2IGF2BP1
HEXBENSG00000049860.92385.738401908.693700.321802.424701.78750HepG2IGF2BP2
HEXBENSG00000049860.91693.657601422.164700.252003.389002.26000HepG2KIF1C
HEXBENSG00000049860.93298.179402262.045000.543904.426803.36770HepG2LARP4
HEXBENSG00000049860.91290.525102024.80930-0.649807.219906.17520HepG2MAGOH
HEXBENSG00000049860.92958.806002036.164700.539105.007404.18100HepG2MATR3
HEXBENSG00000049860.92077.379801336.287100.636409.830308.39790HepG2MSI2
HEXBENSG00000049860.91815.856501122.063000.6944010.712108.37160HepG2NAA15
HEXBENSG00000049860.91667.508902084.14620-0.321802.086001.53220HepG2NCBP2
HEXBENSG00000049860.91925.011002320.26370-0.269402.477501.75840HepG2NOL12
HEXBENSG00000049860.91582.066501198.999600.399903.303902.48630HepG2NSUN2
HEXBENSG00000049860.92382.669501856.153000.360202.689001.97660HepG2PABPC4
HEXBENSG00000049860.92063.106901605.749000.361505.530904.39170HepG2PARN
HEXBENSG00000049860.91219.030901868.62630-0.6162013.6829012.49670HepG2PCBP1
HEXBENSG00000049860.91590.160701149.370300.468207.590606.38790HepG2PRPF4
HEXBENSG00000049860.9755.764701587.48660-1.070707.811804.93370HepG2PSIP1
HEXBENSG00000049860.91364.366901901.46370-0.478908.488907.63980HepG2PTBP1
HEXBENSG00000049860.91653.358902214.89400-0.421803.226702.58930HepG2PUF60
HEXBENSG00000049860.92743.324102351.206800.222403.552002.89730HepG2PUM1
HEXBENSG00000049860.91068.751101584.61550-0.5682012.2859011.14610HepG2PUS1
HEXBENSG00000049860.92457.920301392.054700.820105.868504.86830HepG2RAVER1
HEXBENSG00000049860.93020.336102165.300900.480009.364308.53890HepG2RBM22
HEXBENSG00000049860.9944.431501362.16290-0.528403.535102.33710HepG2RCC2
HEXBENSG00000049860.91423.660302116.09120-0.5718011.8270010.85820HepG2NELFE
HEXBENSG00000049860.91611.627001970.95170-0.290403.629402.93600HepG2RECQL
HEXBENSG00000049860.9814.470101056.93900-0.376003.095002.44990HepG2RPS19
HEXBENSG00000049860.91133.248201547.06770-0.449103.937702.99060HepG2RPS2
HEXBENSG00000049860.91184.244401826.62420-0.625204.931203.86150HepG2RPS3A
HEXBENSG00000049860.91973.439901579.205300.321402.478801.46340HepG2RPS5
HEXBENSG00000049860.91469.09860997.674700.558204.909903.89500HepG2RRP9
HEXBENSG00000049860.92360.175301514.256000.640204.491202.52680HepG2RTF1
HEXBENSG00000049860.91242.399401444.68570-0.217602.278401.68470HepG2SAFB2
HEXBENSG00000049860.92291.559301455.537600.654702.524401.88080HepG2SF3A3
HEXBENSG00000049860.92434.063301684.745700.530709.935508.83590HepG2SMN1
HEXBENSG00000049860.92627.876401489.239100.819202.223101.52650HepG2SNRNP70
HEXBENSG00000049860.93034.961202445.674400.311305.880105.22540HepG2SRFBP1
HEXBENSG00000049860.91497.203602066.27010-0.464808.776008.04020HepG2SRSF1
HEXBENSG00000049860.92051.000001440.153200.510003.863802.65880HepG2SRSF3
HEXBENSG00000049860.93052.752902186.884100.4811010.888309.75880HepG2SRSF5
HEXBENSG00000049860.91436.373701858.53990-0.371705.060104.16370HepG2SRSF7
HEXBENSG00000049860.92978.131701681.062800.8249010.864409.89740HepG2SRSF9
HEXBENSG00000049860.91201.366402123.50590-0.8218020.3936019.28050HepG2SSB
HEXBENSG00000049860.92086.413001300.883500.681404.565803.00940HepG2SUB1
HEXBENSG00000049860.91880.116902487.09060-0.403608.744407.74250HepG2SUCLG1
HEXBENSG00000049860.91655.884901114.899600.570607.938806.40120HepG2SUPT6H
HEXBENSG00000049860.94089.542101857.379401.1386047.7119045.75390HepG2TAF15
HEXBENSG00000049860.92295.602201317.989600.8004013.0807011.68660HepG2TARDBP
HEXBENSG00000049860.92068.475801706.535100.277402.024901.30760HepG2TIA1
HEXBENSG00000049860.9978.071001576.31320-0.6885011.9738011.06150HepG2TIAL1
HEXBENSG00000049860.91885.580201590.412300.245502.842802.27310HepG2TRIM56
HEXBENSG00000049860.91437.42030768.766100.9028012.8475011.23970HepG2UCHL5
HEXBENSG00000049860.92212.889101290.838800.7775024.9341023.26060HepG2UPF1
HEXBENSG00000049860.91574.045101326.806100.246402.437401.44340HepG2UTP18
HEXBENSG00000049860.91840.432401246.255000.5623011.9697010.86000HepG2UTP3
HEXBENSG00000049860.92048.583901368.719900.581704.045002.51280HepG2XRCC5
HEXBENSG00000049860.9861.638501281.01460-0.572104.828903.88080HepG2XRN2
HEXBENSG00000049860.92805.615401419.676400.9827050.9546049.36680HepG2ZNF622
HEXBENSG00000049860.9903.568901303.44200-0.528605.868104.08080K562AARS
HEXBENSG00000049860.92850.905302078.355000.455909.779708.79570K562AGGF1
HEXBENSG00000049860.92858.631302283.790700.323803.014001.97590K562AKAP8
HEXBENSG00000049860.93003.265002162.620800.473705.859104.88590K562AKAP8L
HEXBENSG00000049860.92912.169402269.106400.359905.225903.92660K562ATP5C1
HEXBENSG00000049860.92008.645001265.095200.666908.328806.77480K562BOP1
HEXBENSG00000049860.91814.263601331.060400.446705.678503.51000K562CEBPZ
HEXBENSG00000049860.92441.202301768.776900.464702.355901.38940K562CNOT7
HEXBENSG00000049860.91955.350701345.199800.539507.556006.25550K562CPSF6
HEXBENSG00000049860.95388.710203744.681500.525009.210907.47950K562CELF1
HEXBENSG00000049860.91892.492601529.874200.306803.730002.32230K562DDX21
HEXBENSG00000049860.91852.713102222.05740-0.262303.164602.47450K562DDX47
HEXBENSG00000049860.92811.494202327.146200.272703.381602.40000K562DKC1
HEXBENSG00000049860.9403.19630700.31620-0.796504.537403.21970K562EIF3A
HEXBENSG00000049860.9999.472801325.03310-0.406802.623201.61790K562EIF3D
HEXBENSG00000049860.91021.168201432.80110-0.488606.803805.56770K562EIF3G
HEXBENSG00000049860.91158.923501641.13930-0.501905.418804.27160K562EIF4A3
HEXBENSG00000049860.92524.679803044.91800-0.270303.954802.83600K562EIF4G2
HEXBENSG00000049860.91915.032901413.237800.438304.483903.38470K562FIP1L1
HEXBENSG00000049860.92027.484801368.630200.566904.390503.31190K562FMR1
HEXBENSG00000049860.91219.528901706.72390-0.484907.330506.40910K562FXR1
HEXBENSG00000049860.92557.030401858.185900.460502.217201.59500K562G3BP2
HEXBENSG00000049860.92609.508501610.984900.695703.133701.81170K562HNRNPA2B1
HEXBENSG00000049860.92417.822101915.994200.335502.830102.02540K562HSPD1
HEXBENSG00000049860.93308.693802295.087500.527607.279905.78360K562KIF1C
HEXBENSG00000049860.91614.577101096.604300.558004.114502.95590K562KRR1
HEXBENSG00000049860.91094.748301446.47260-0.401903.147201.56790K562LIN28B
HEXBENSG00000049860.91648.511302076.49360-0.333002.709601.87930K562MAGOH
HEXBENSG00000049860.92827.654902196.958400.364004.064602.68370K562MAK16
HEXBENSG00000049860.93193.207502571.076800.312503.169202.18440K562MBNL1
HEXBENSG00000049860.92663.997501802.138100.563802.543501.70540K562NAA15
HEXBENSG00000049860.92072.864201813.070700.193102.625901.89640K562NSUN2
HEXBENSG00000049860.92561.140201699.283100.591803.467802.06780K562PABPC1
HEXBENSG00000049860.92343.476201408.598200.734303.501602.35000K562PABPN1
HEXBENSG00000049860.91228.269901847.72360-0.589106.054204.59020K562PCBP2
HEXBENSG00000049860.92040.005501604.362400.346502.875602.03820K562PPIG
HEXBENSG00000049860.9802.803701278.29850-0.671108.006306.30280K562PSIP1
HEXBENSG00000049860.91582.627602017.37870-0.350203.217202.50770K562PTBP1
HEXBENSG00000049860.94635.365503534.293600.391204.328802.96940K562PUM1
HEXBENSG00000049860.94129.162902144.739500.9449018.8999017.51440K562PUS1
HEXBENSG00000049860.93026.283802089.714700.5341010.314409.19400K562RBM15
HEXBENSG00000049860.91108.963401644.49140-0.568405.619404.12710K562RPS3
HEXBENSG00000049860.91708.970201231.314600.472803.110101.69670K562RRP9
HEXBENSG00000049860.9819.563701065.30700-0.378303.091601.94600K562SAFB
HEXBENSG00000049860.92176.153101789.052800.282502.224301.48700K562SF3A3
HEXBENSG00000049860.91712.359301221.360500.487403.985402.80530K562SF3B1
HEXBENSG00000049860.9844.674601105.90260-0.388803.083401.98720K562SRFBP1
HEXBENSG00000049860.91260.029201977.60630-0.650308.076906.87830K562SRSF1
HEXBENSG00000049860.91151.907801587.75000-0.463004.244502.89810K562SRSF4
HEXBENSG00000049860.92232.612101695.866400.396603.219801.84880K562STAU1
HEXBENSG00000049860.93099.036801769.428200.808403.723501.96870K562SUPT6H
HEXBENSG00000049860.91509.647401166.001400.372502.584601.60600K562SUPV3L1
HEXBENSG00000049860.9919.125701199.24360-0.383803.744302.78920K562SYNCRIP
HEXBENSG00000049860.91593.338202001.67650-0.329202.536401.85730K562TARDBP
HEXBENSG00000049860.91580.761001930.78790-0.288602.320201.57800K562TIA1
HEXBENSG00000049860.92352.903602008.694200.228102.563001.34670K562TROVE2
HEXBENSG00000049860.92266.934401860.306800.285102.856302.04000K562U2AF2
HEXBENSG00000049860.92391.517001922.438100.314905.076704.13470K562UPF1
HEXBENSG00000049860.91474.180401710.58490-0.214602.464801.66340K562WDR43
HEXBENSG00000049860.93081.815901740.829700.823904.048701.95420K562YTHDC2
HEXBENSG00000049860.93543.131402982.911800.248202.047801.31750K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HEXB is not available on ENCORE database.





3 RBPs can affect the splicing of HEXB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHEXBENSG00000049860.9chr5+740113137401151574009330740094607401241174012498-0.071000.000040.00082excludedK562AQR
A3SSHEXBENSG00000049860.9chr5+740146217401484574014733740148457401404474014188-0.090000.005980.03383shorterK562AQR
A3SSHEXBENSG00000049860.9chr5+740093307400946074009395740094607400104374001145-0.142000.000000.00009shorterHepG2U2AF1
MXEHEXBENSG00000049860.9chr5+74011313740115157401241174012498740093307400946074014115740141880.054000.000000.000021includedK562AQR
MXEHEXBENSG00000049860.9chr5+74016252740163437401646774016572740146217401479674016942740171130.158000.000040.001921includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HEXB is not avaliable on ENCORE database.