AIFM2

General Information

Gene Name       : AIFM2
Gene ID             : ENSG00000042286.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: AIFM2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878AIFM2ENSG00000042286.143.588.275.92ENCSR000AEF
HepG2AIFM2ENSG00000042286.1435.8719.0927.48ENCSR985KAT
K562AIFM2ENSG00000042286.148.746.287.51ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for AIFM2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • AIFM2 RNA is bound by 10 proteins.  







eCLIP assay for AIFM2 is not avaliable on ENCORE database.





10 proteins are bound to AIFM2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr107187221471872333-3'-UTR,intron-Distal5.108386.99975K562UPF1
chr107187343371873510-3'-UTR,intron-Distal3.318514.96603K562UPF1
chr107187363171873726-3'-UTR,intron-Distal4.613116.20043HepG2UPF1
chr107187358971873713-3'-UTR,intron-Distal4.989556.75461HepG2AKAP1
chr107189249171892563-5'-UTR,intron-Distal4.1962019.61701HepG2DDX3X
chr107189258171892631-5'-UTR,intron-Distal4.282096.83552HepG2DDX3X
chr107189248371892572-5'-UTR,intron-Distal3.454647.69908HepG2NCBP2
chr107188373771883848-5'-UTR,CDS,intron-Distal3.9124416.10838HepG2DDX3X
chr107189243971892496-5'-UTR,intron-Distal3.233128.98788HepG2PRPF8
chr107187403371874087-CDS,intron-Distal,intron-Proximal3.715803.98203HepG2PRPF8
chr107188311471883171-CDS,intron-Distal,intron-Proximal3.302757.35853HepG2PRPF8
chr107187650271876618-CDS,intron-Distal,intron-Proximal4.958767.09786HepG2AQR
chr107188079471880868-CDS,intron-Distal,intron-Proximal4.494289.76577HepG2PRPF8
chr107187648571876536-CDS,intron-Distal,intron-Proximal3.815225.31213HepG2PRPF8
chr107187751671877587-CDS,intron-Distal,intron-Proximal4.074996.19659HepG2AQR
chr107187479571874862-CDS,intron-Distal3.692754.41267HepG2PPIG
chr107187751471877587-CDS,intron-Distal,intron-Proximal6.0050813.87810HepG2PRPF8
chr107187633071876379-CDS,intron-Distal,intron-Proximal4.780034.35676HepG2PRPF8
chr107187638171876511-CDS,intron-Distal4.080314.23295HepG2GRWD1
chr107188022571880264-CDS,intron-Distal,intron-Proximal3.916545.05356HepG2PRPF8
chr107188329571883342-intron-Distal,intron-Proximal3.289233.10102HepG2SF3B4
chr107187457771874640-intron-Distal,intron-Proximal5.118505.74423HepG2BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for AIFM2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for AIFM2 is not available on ENCORE database.

  • 95 RBPs can affect the levels of AIFM2.  








The Knockdown/knockout RNA-Seq assay for AIFM2 is not available on ENCORE database.





95 RBPs can affect the gene expression of AIFM2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
AIFM2ENSG00000042286.10341.04140625.04990-0.874009.213007.40040HepG2AATF
AIFM2ENSG00000042286.101283.81510886.565400.534004.399003.23120HepG2ABCF1
AIFM2ENSG00000042286.10768.58930979.86220-0.350403.997303.29140HepG2ACO1
AIFM2ENSG00000042286.10780.95260589.596000.405402.713001.72390HepG2ADAR
AIFM2ENSG00000042286.10645.207501453.19910-1.1714016.1285014.95320HepG2AKAP1
AIFM2ENSG00000042286.101800.30850984.450900.8708024.7614022.81780HepG2AKAP8L
AIFM2ENSG00000042286.10810.993201202.33280-0.568105.109304.05810HepG2ASCC1
AIFM2ENSG00000042286.10968.227001316.70360-0.443505.744404.81660HepG2AUH
AIFM2ENSG00000042286.10422.41800567.33580-0.425502.880402.09540HepG2CALR
AIFM2ENSG00000042286.101514.974401142.320700.407203.141802.31960HepG2CIRBP
AIFM2ENSG00000042286.10816.35970602.318800.438601.969401.37830HepG2CPSF6
AIFM2ENSG00000042286.10878.25020599.044600.551904.230302.92960HepG2CSTF2
AIFM2ENSG00000042286.101348.072901116.131600.272302.751602.11010HepG2CELF1
AIFM2ENSG00000042286.101585.554201200.049300.401807.318706.19640HepG2DAZAP1
AIFM2ENSG00000042286.101051.40820689.128800.609406.619605.62020HepG2DDX21
AIFM2ENSG00000042286.10446.63870722.36600-0.693604.876503.06710HepG2DDX28
AIFM2ENSG00000042286.10387.85320558.81350-0.526904.099902.47750HepG2DDX52
AIFM2ENSG00000042286.10694.43960953.94550-0.458102.622501.86700HepG2DDX55
AIFM2ENSG00000042286.10285.06290683.98380-1.262708.505206.85160HepG2DDX59
AIFM2ENSG00000042286.10851.76820662.613900.362202.364801.42960HepG2DDX5
AIFM2ENSG00000042286.10959.24260666.754200.524603.098502.12620HepG2EEF2
AIFM2ENSG00000042286.10406.00600634.93000-0.645104.221002.83880HepG2AGO1
AIFM2ENSG00000042286.103193.601001270.085801.3302024.8682023.00010HepG2EIF4A3
AIFM2ENSG00000042286.10592.51620767.95580-0.374202.378201.36460HepG2ESF1
AIFM2ENSG00000042286.10325.92320483.73530-0.569704.583703.04440HepG2FAM120A
AIFM2ENSG00000042286.10631.20620895.20700-0.504103.287202.45460HepG2FIP1L1
AIFM2ENSG00000042286.10611.19600820.63520-0.425103.522002.63970HepG2FUBP3
AIFM2ENSG00000042286.10743.186801188.94430-0.677906.502505.50630HepG2G3BP1
AIFM2ENSG00000042286.101092.61580602.234100.859309.502407.57890HepG2GNB2L1
AIFM2ENSG00000042286.10609.35900935.47700-0.618409.881708.18500HepG2HDGF
AIFM2ENSG00000042286.10412.88490668.96760-0.696202.774601.40720HepG2HLTF
AIFM2ENSG00000042286.10613.92270431.661100.508102.660401.32330HepG2HNRNPA0
AIFM2ENSG00000042286.10744.18330599.405400.312001.895601.34950HepG2HNRNPA1
AIFM2ENSG00000042286.101331.434601093.133000.284403.773902.99410HepG2HNRNPL
AIFM2ENSG00000042286.10509.86900651.53800-0.353701.934801.39980HepG2HNRNPLL
AIFM2ENSG00000042286.10469.38150662.30330-0.496704.127403.39840HepG2HNRNPU
AIFM2ENSG00000042286.101251.54380930.702500.427204.635003.71920HepG2IGF2BP1
AIFM2ENSG00000042286.10337.24410486.38410-0.528302.841101.62930HepG2KHDRBS1
AIFM2ENSG00000042286.101717.322301065.881800.688006.156604.90830HepG2LARP4
AIFM2ENSG00000042286.102291.761001282.409000.8375011.5398010.23460HepG2MAGOH
AIFM2ENSG00000042286.102527.606601289.505900.9709013.7133012.38510HepG2MATR3
AIFM2ENSG00000042286.10346.27490566.49400-0.710103.181002.05220HepG2METAP2
AIFM2ENSG00000042286.101012.680501319.81540-0.382202.523001.91660HepG2NCBP2
AIFM2ENSG00000042286.10404.35110655.58910-0.697209.004107.61590HepG2PARN
AIFM2ENSG00000042286.10853.162701210.08600-0.504207.429306.51310HepG2PCBP1
AIFM2ENSG00000042286.101097.56580457.581001.2621012.292109.34790HepG2PNPT1
AIFM2ENSG00000042286.10462.25250590.72480-0.353802.620801.90230HepG2PPIL4
AIFM2ENSG00000042286.10502.41260620.49260-0.304502.195701.49930HepG2PRPF4
AIFM2ENSG00000042286.101126.01550735.470700.614404.753703.72660HepG2PRPF8
AIFM2ENSG00000042286.10628.394601231.38660-0.9705019.4840018.28000HepG2PTBP1
AIFM2ENSG00000042286.101638.104601135.948800.528006.450405.59090HepG2PUF60
AIFM2ENSG00000042286.10593.67760998.05060-0.7494014.9154013.68610HepG2PUS1
AIFM2ENSG00000042286.10606.420301333.45410-1.1368026.3436024.70320HepG2QKI
AIFM2ENSG00000042286.10737.83170983.00050-0.413903.884102.88730HepG2RBM15
AIFM2ENSG00000042286.10479.277601210.25880-1.3364029.2912027.26910HepG2RBM25
AIFM2ENSG00000042286.10275.57250492.83570-0.838704.793502.79140HepG2RBM47
AIFM2ENSG00000042286.101085.69940577.919800.909605.769204.23370HepG2RCC2
AIFM2ENSG00000042286.101168.923101370.34950-0.229401.914401.44550HepG2NELFE
AIFM2ENSG00000042286.10571.208701276.41310-1.1600026.6656025.09980HepG2RECQL
AIFM2ENSG00000042286.102059.293101018.140901.0161011.4904010.26380HepG2RPLP0
AIFM2ENSG00000042286.10909.73240656.309900.471003.083302.23750HepG2RPS2
AIFM2ENSG00000042286.101258.42630670.003200.9093011.297609.15360HepG2RPS5
AIFM2ENSG00000042286.10523.69170727.49140-0.474202.864702.06650HepG2RRP9
AIFM2ENSG00000042286.10247.93430589.82090-1.2503023.2518021.62790HepG2SAFB2
AIFM2ENSG00000042286.10793.78370528.608300.586404.826803.59920HepG2SERBP1
AIFM2ENSG00000042286.101608.58300896.076000.844006.583005.51580HepG2SF3A3
AIFM2ENSG00000042286.10506.06460644.86250-0.349702.035901.42550HepG2SF3B1
AIFM2ENSG00000042286.10741.768501281.89100-0.7892012.6462011.52360HepG2SF3B4
AIFM2ENSG00000042286.10822.17510687.848500.257302.266501.67470HepG2SMN1
AIFM2ENSG00000042286.101077.01060650.117200.728205.890504.45380HepG2SMNDC1
AIFM2ENSG00000042286.10578.574001427.16910-1.3026026.4890025.35170HepG2SRFBP1
AIFM2ENSG00000042286.101637.299901338.074400.291103.764603.23460HepG2SRSF1
AIFM2ENSG00000042286.101090.21570928.573600.231402.044601.43610HepG2SRSF7
AIFM2ENSG00000042286.101527.227601088.644500.488309.150908.25040HepG2SRSF9
AIFM2ENSG00000042286.102240.564101239.041700.8545010.255909.38850HepG2SSB
AIFM2ENSG00000042286.101078.958101275.55720-0.241502.421901.83240HepG2SUCLG1
AIFM2ENSG00000042286.10506.841301202.87350-1.2469023.3977021.98840HepG2TAF15
AIFM2ENSG00000042286.10454.36920635.19220-0.483303.354302.56490HepG2TARDBP
AIFM2ENSG00000042286.10542.125501105.10700-1.0275018.9693016.85750HepG2TIA1
AIFM2ENSG00000042286.101273.44630643.618100.9844020.0523018.93230HepG2TIAL1
AIFM2ENSG00000042286.101091.37970794.681400.457606.513005.51680HepG2UPF1
AIFM2ENSG00000042286.10929.86500767.235200.277302.384401.81890HepG2UTP3
AIFM2ENSG00000042286.10366.78870626.14290-0.771503.475002.04140HepG2XRCC5
AIFM2ENSG00000042286.101508.72170873.998900.7875023.4934022.28920HepG2ZNF622
AIFM2ENSG00000042286.10668.26700481.695800.472204.754304.04410K562AGGF1
AIFM2ENSG00000042286.10664.29270501.233000.406202.921602.25040K562AKAP8L
AIFM2ENSG00000042286.10437.37420292.075900.582403.967102.42090K562CIRBP
AIFM2ENSG00000042286.10327.35970539.32060-0.720307.574305.99430K562DKC1
AIFM2ENSG00000042286.10680.60410349.576800.961107.970505.84330K562EEF2
AIFM2ENSG00000042286.10300.42410209.730100.518402.746501.95230K562EIF3G
AIFM2ENSG00000042286.10159.29660269.07940-0.756303.990702.60730K562FKBP4
AIFM2ENSG00000042286.10528.03280349.910100.593503.669502.98790K562FXR1
AIFM2ENSG00000042286.1090.78110175.11120-0.947803.253602.47650K562G3BP2
AIFM2ENSG00000042286.10613.04020458.522100.418903.102901.96410K562HNRNPA1
AIFM2ENSG00000042286.10410.10560310.076500.403302.133501.60060K562HNRNPC
AIFM2ENSG00000042286.10446.13320272.692800.710104.395802.97690K562IGF2BP2
AIFM2ENSG00000042286.10417.28990286.412200.542903.669402.69360K562MAGOH
AIFM2ENSG00000042286.10387.37150285.804300.438602.560401.67600K562MATR3
AIFM2ENSG00000042286.10419.89080278.280700.593404.569303.73660K562PTBP1
AIFM2ENSG00000042286.10646.04890497.037700.378202.098201.61270K562PUS1
AIFM2ENSG00000042286.10354.99920257.714400.461902.464001.48010K562SRSF5
AIFM2ENSG00000042286.10376.68370276.076600.448202.322801.67150K562TARDBP
AIFM2ENSG00000042286.10388.66560266.318300.545303.500002.56340K562TIA1
AIFM2ENSG00000042286.10390.47530261.438900.578703.537802.27370K562TRA2A
AIFM2ENSG00000042286.10521.66150423.922400.299202.069401.32980K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for AIFM2 is not available on ENCORE database.





4 RBPs can affect the splicing of AIFM2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAIFM2ENSG00000042286.10chr10-718808477188096771880262718803557188316071883276-0.130000.000880.01852excludedHepG2U2AF1
SEAIFM2ENSG00000042286.10chr10-718808477188096771880262718803557188316071883276-0.093000.000760.02467excludedHepG2SF3A3
SEAIFM2ENSG00000042286.10chr10-7188084771880967718802627188035571883160718832760.083000.000020.00474includedHepG2SUPV3L1
A3SSAIFM2ENSG00000042286.10chr10-7187756771877720718775677187767671880262718803550.058000.007830.04281longerK562AQR
A3SSAIFM2ENSG00000042286.10chr10-7187467571874913718746757187487671876377718765300.053000.000070.00061longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for AIFM2 is not avaliable on ENCORE database.