MYLK

General Information

Gene Name       : MYLK
Gene ID             : ENSG00000065534.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MYLK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MYLKENSG00000065534.180.050.490.27ENCSR000AEF
HepG2MYLKENSG00000065534.1825.8323.6124.72ENCSR985KAT
K562MYLKENSG00000065534.180.050.150.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MYLK is not avaliable on ENCORE database.



Proteins bound to RNA
  • MYLK RNA is bound by 11 proteins.  







eCLIP assay for MYLK is not avaliable on ENCORE database.





11 proteins are bound to MYLK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3123382975123383113-3'-UTR,CDS,intron-Distal,intron-Proximal3.970993.12746HepG2GRWD1
chr3123385053123385191-3'-UTR,CDS,intron-Distal,intron-Proximal3.176534.51003HepG2PPIG
chr3123419033123419154-3'-UTR,CDS,intron-Distal4.180877.16354HepG2FXR2
chr3123385063123385194-3'-UTR,CDS,intron-Distal,intron-Proximal3.256874.48452HepG2FXR2
chr3123452644123452762-3'-UTR,CDS,intron-Distal4.384183.68241HepG2G3BP1
chr3123419274123419346-3'-UTR,CDS,intron-Distal3.814884.83483HepG2FXR2
chr3123419531123419617-3'-UTR,CDS,intron-Distal4.337633.61890HepG2G3BP1
chr3123367816123367912-3'-UTR,CDS,intron-Distal,intron-Proximal4.126903.96931HepG2G3BP1
chr3123376053123376210-3'-UTR,CDS,intron-Distal4.967316.71899HepG2FXR2
chr3123457752123457849-3'-UTR,CDS,intron-Distal,intron-Proximal3.372823.28366HepG2BCLAF1
chr3123366135123366274-3'-UTR,CDS,intron-Distal3.841835.09222HepG2FXR2
chr3123385063123385182-3'-UTR,CDS,intron-Distal,intron-Proximal4.131583.79347HepG2GRWD1
chr3123452548123452644-3'-UTR,CDS,intron-Distal3.324693.50786HepG2G3BP1
chr3123456181123456313-3'-UTR,CDS,intron-Distal,intron-Proximal3.015935.14343HepG2PPIG
chr3123339071123339184-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.045153.68241HepG2G3BP1
chr3123359123123359229-3'-UTR,CDS,intron-Distal,intron-Proximal3.938423.34184HepG2GRWD1
chr3123420252123420352-3'-UTR,CDS,intron-Distal,intron-Proximal4.042293.56019HepG2GRWD1
chr3123345650123345753-3'-UTR,CDS,intron-Distal,intron-Proximal4.427864.14322HepG2FXR2
chr3123427533123427669-3'-UTR,CDS,intron-Distal,intron-Proximal4.093083.31827HepG2GRWD1
chr3123411585123411695-3'-UTR,CDS,intron-Distal3.175933.79741HepG2GRWD1
chr3123456152123456270-3'-UTR,CDS,intron-Distal,intron-Proximal3.673338.78144HepG2PRPF8
chr3123512650123512694-5'-UTR,CDS,intron-Distal,intron-Proximal3.354963.32039HepG2PPIG
chr3123471208123471316-CDS,intron-Distal3.824693.11282HepG2G3BP1
chr3123512431123512478-intron-Distal,intron-Proximal4.607997.43919HepG2XPO5
chr3123348099123348163-intron-Distal4.280534.17531HepG2RBFOX2
chr3123353009123353076-intron-Distal4.506824.80665HepG2QKI
chr3123369208123369353-intron-Distal3.680543.41538HepG2HNRNPL
chr3123433782123433884-intron-Distal4.515844.40847HepG2PTBP1
chr3123518667123518784-intron-Distal3.396927.91657HepG2PPIG
chr3123352834123352947-intron-Distal3.787755.81617HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MYLK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MYLK is not available on ENCORE database.

  • 95 RBPs can affect the levels of MYLK.  








The Knockdown/knockout RNA-Seq assay for MYLK is not available on ENCORE database.





95 RBPs can affect the gene expression of MYLK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MYLKENSG00000065534.14356.39480700.96550-0.9759011.998509.99490HepG2AATF
MYLKENSG00000065534.14336.51700682.65240-1.0205019.2020017.91340HepG2ACO1
MYLKENSG00000065534.14868.81490627.318700.469803.624902.50150HepG2ADAR
MYLKENSG00000065534.14215.039301011.82170-2.2343041.9510040.23420HepG2AKAP1
MYLKENSG00000065534.14313.90550685.83520-1.1275021.3000019.46930HepG2AKAP8L
MYLKENSG00000065534.14784.800601080.98580-0.461904.467303.63090HepG2AUH
MYLKENSG00000065534.14370.59740914.09510-1.3025017.6148015.09110HepG2BCCIP
MYLKENSG00000065534.14151.54320937.67180-2.6294067.6905065.59920HepG2BOP1
MYLKENSG00000065534.14897.26060645.548000.474904.196102.69670HepG2BUD13
MYLKENSG00000065534.14379.01950884.67420-1.2229022.4282020.63330HepG2CALR
MYLKENSG00000065534.14796.426001199.79870-0.591204.260703.03810HepG2CCAR1
MYLKENSG00000065534.141867.85640795.385201.2316023.5094021.55260HepG2CIRBP
MYLKENSG00000065534.14552.29410682.47450-0.305302.624101.97230HepG2CKAP4
MYLKENSG00000065534.14113.24410371.58240-1.7142013.9124012.24810HepG2CNOT7
MYLKENSG00000065534.14337.26020860.82510-1.3519020.9021019.23420HepG2CPSF6
MYLKENSG00000065534.14524.091401025.30940-0.9682025.0500023.24430HepG2DAZAP1
MYLKENSG00000065534.14438.65860680.72380-0.634005.171803.32640HepG2DDX28
MYLKENSG00000065534.14699.06330468.621100.576904.914003.21720HepG2DDX47
MYLKENSG00000065534.141083.89230653.105800.7307013.2189011.96430HepG2DKC1
MYLKENSG00000065534.14390.17100631.64840-0.695008.154907.00030HepG2DNAJC21
MYLKENSG00000065534.141175.28880699.763800.748008.217206.72040HepG2EEF2
MYLKENSG00000065534.14898.18560653.609600.458504.159702.73620HepG2EIF2S2
MYLKENSG00000065534.141146.46990730.328200.650508.665406.96700HepG2EIF3G
MYLKENSG00000065534.14552.13390746.35690-0.434802.909101.78980HepG2ESF1
MYLKENSG00000065534.14928.754301241.14530-0.418305.468904.67160HepG2ETF1
MYLKENSG00000065534.14473.98570736.99870-0.636806.348704.74200HepG2FASTKD2
MYLKENSG00000065534.14456.36670869.94840-0.930708.548507.28110HepG2FIP1L1
MYLKENSG00000065534.141296.09780892.507000.538104.177903.34080HepG2FXR1
MYLKENSG00000065534.14664.71840505.766100.394202.372001.55000HepG2GEMIN5
MYLKENSG00000065534.14125.23590343.94540-1.4575011.418209.19480HepG2GRSF1
MYLKENSG00000065534.14421.66280802.63910-0.928707.180504.85510HepG2GTF2F1
MYLKENSG00000065534.14846.50690637.700500.408503.006602.33560HepG2HNRNPA1
MYLKENSG00000065534.14173.17100306.68380-0.824604.732302.88470HepG2HNRNPAB
MYLKENSG00000065534.14363.51250709.34760-0.9645011.245209.92590HepG2HNRNPC
MYLKENSG00000065534.14472.84130321.851500.554902.918301.35970HepG2HNRNPD
MYLKENSG00000065534.14492.10870838.43690-0.768707.991206.85260HepG2HNRNPK
MYLKENSG00000065534.14495.97340934.00460-0.9132020.5777018.90340HepG2HNRNPL
MYLKENSG00000065534.14623.45560931.21500-0.578804.940904.12430HepG2HNRNPLL
MYLKENSG00000065534.14138.87540789.78980-2.5077018.7533016.47080HepG2IGF2BP3
MYLKENSG00000065534.14463.70100719.77880-0.634409.294708.03150HepG2ILF2
MYLKENSG00000065534.14364.45570853.39840-1.2275013.1439010.59400HepG2KRR1
MYLKENSG00000065534.14485.69250701.10990-0.529604.461403.01420HepG2LARP7
MYLKENSG00000065534.14524.67010736.12250-0.488503.753002.34000HepG2LIN28B
MYLKENSG00000065534.14676.85450892.81920-0.399502.516901.88910HepG2MAGOH
MYLKENSG00000065534.141146.84330897.797100.353102.008201.46610HepG2MATR3
MYLKENSG00000065534.14320.62330594.50160-0.890804.988003.60320HepG2METAP2
MYLKENSG00000065534.14884.70510704.167400.329202.329001.58360HepG2MSI2
MYLKENSG00000065534.141412.64790918.929700.620305.775804.87580HepG2NCBP2
MYLKENSG00000065534.14703.023201016.69010-0.532206.634205.45850HepG2NOL12
MYLKENSG00000065534.14532.45900733.10260-0.461303.720601.84880HepG2NUP35
MYLKENSG00000065534.14231.25760697.45930-1.5926036.6795034.31400HepG2PARN
MYLKENSG00000065534.14610.48680858.90640-0.492505.989205.15010HepG2PCBP1
MYLKENSG00000065534.14769.36630628.492800.291702.236201.56660HepG2PPIL4
MYLKENSG00000065534.14892.71190743.243400.264302.173601.48050HepG2PRPF4
MYLKENSG00000065534.141398.70190847.391900.722905.234003.59950HepG2PRPF6
MYLKENSG00000065534.141111.71010693.125800.681506.146204.99400HepG2PRPF8
MYLKENSG00000065534.14693.870801030.19610-0.5702010.364009.37000HepG2PUM1
MYLKENSG00000065534.14417.303501029.46100-1.3027028.5684026.57310HepG2PUM2
MYLKENSG00000065534.141540.98360695.321501.1480040.5617038.75730HepG2PUS1
MYLKENSG00000065534.14710.468301037.36180-0.546106.852906.12360HepG2RBM22
MYLKENSG00000065534.141153.89220859.035200.425604.035603.23460HepG2RBM25
MYLKENSG00000065534.14487.04010845.42930-0.795608.670806.90990HepG2RBM27
MYLKENSG00000065534.14174.66170358.83040-1.038706.941504.59280HepG2RBM47
MYLKENSG00000065534.141078.56850686.526300.651605.833804.28800HepG2RCC2
MYLKENSG00000065534.141180.92780972.647700.279802.030101.55140HepG2NELFE
MYLKENSG00000065534.14559.08410764.21160-0.450902.131701.30210HepG2RPS10
MYLKENSG00000065534.14588.50940372.962000.657904.026003.06060HepG2RPS3A
MYLKENSG00000065534.14581.19180795.91500-0.453603.241602.07270HepG2RPS5
MYLKENSG00000065534.14435.48370627.51350-0.527005.788904.91040HepG2SAFB2
MYLKENSG00000065534.14698.05170909.90480-0.382403.905003.22280HepG2SF3B4
MYLKENSG00000065534.14447.72710759.05400-0.761603.131401.42810HepG2SLTM
MYLKENSG00000065534.14411.17310793.51650-0.948508.467506.74720HepG2SMNDC1
MYLKENSG00000065534.14679.075201025.56350-0.594803.407302.53540HepG2SNRNP70
MYLKENSG00000065534.14882.393801171.65130-0.409005.419504.78260HepG2SRFBP1
MYLKENSG00000065534.141594.44590949.753400.7473017.8170016.83570HepG2SRSF1
MYLKENSG00000065534.14810.28490958.18960-0.241902.049901.50110HepG2SRSF5
MYLKENSG00000065534.14371.99470772.68350-1.0546021.2092019.94390HepG2SRSF9
MYLKENSG00000065534.141744.606101017.252100.7781021.1683020.04070HepG2SSB
MYLKENSG00000065534.14366.59840850.91580-1.2148015.6851013.08820HepG2SSRP1
MYLKENSG00000065534.14188.84520324.38020-0.780504.620603.16260HepG2STIP1
MYLKENSG00000065534.14505.589701089.75430-1.1080030.8652029.16780HepG2SUCLG1
MYLKENSG00000065534.14531.52060861.51740-0.696805.124703.32780HepG2SUGP2
MYLKENSG00000065534.141935.75990853.702701.1810038.2080036.43580HepG2TAF15
MYLKENSG00000065534.14531.22740907.70970-0.772908.627507.44710HepG2TARDBP
MYLKENSG00000065534.14273.49130690.83150-1.3368029.2415027.64930HepG2TRIM56
MYLKENSG00000065534.14581.61700744.23450-0.355702.011301.46650HepG2U2AF1
MYLKENSG00000065534.14213.79980528.46350-1.3055016.0215014.23320HepG2UCHL5
MYLKENSG00000065534.14432.66440819.07510-0.920707.543005.82730HepG2UPF2
MYLKENSG00000065534.14598.51460811.77460-0.439704.537703.23520HepG2UTP18
MYLKENSG00000065534.14964.13300762.494700.338403.467702.81070HepG2UTP3
MYLKENSG00000065534.14515.71690765.01870-0.568903.132601.78390HepG2XRCC5
MYLKENSG00000065534.14588.10140855.48590-0.540703.141102.00850HepG2XRCC6
MYLKENSG00000065534.14673.04350880.70130-0.388002.726002.00640HepG2XRN2
MYLKENSG00000065534.14672.96720868.59900-0.368204.331803.68790HepG2ZNF622
MYLKENSG00000065534.1442.116801.101905.256309.894508.82180K562HNRNPC
MYLKENSG00000065534.1444.8745014.136501.666403.069202.19280K562PCBP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MYLK is not available on ENCORE database.





2 RBPs can affect the splicing of MYLK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMYLKENSG00000065534.14chr3-123451742123451949123444790123444925123452533123453069-0.689000.000000.00000excludedHepG2SRSF1
SEMYLKENSG00000065534.14chr3-123451742123451949123444790123444925123452533123453069-0.572000.000010.00082excludedHepG2SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MYLK is not avaliable on ENCORE database.