HNRNPD

General Information

Gene Name : HNRNPD
Gene ID : ENSG00000138668.18
Essential Gene : No

Functions

Splicing regulation
RNA stability & decay
microRNA processing
Translation regulation
Viral RNA regulation
Other

Localization

Not Available

Domains (AlphaFold: HNRNPD)

RRM

Antibody Validation

Cell Signaling Technology: 12382

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	HNRNPD	ENSG00000138668.18	769.79	600.02	684.90	ENCSR000AEF
HepG2	HNRNPD	ENSG00000138668.18	245.57	485.93	365.75	ENCSR985KAT
K562	HNRNPD	ENSG00000138668.18	614.60	642.46	628.53	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	HNRNPD-BGHLV22-HepG2	ENCSR660MZN	HNRNPD	HepG2	Released		ENCSR279HMU	shRNA	KD% = no clear band,no clear band
RNA Bind-n-Seq	RBNS: HNRNPD	ENCSR175OMA	HNRNPD	cell-free sample	Released

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
HNRNPD	ENCAB870XOX	12382	1		Released, ENCODE3	Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
HNRNPD	K562	shRNA			BGKLV24-33,BGKLV24-34	BGKLV24-1,BGKLV24-2		NotSatisfied	ENCODE3
HNRNPD	HepG2	shRNA	ENCSR660MZN	ENCSR279HMU	HNRNPD-BGHLV22-25_17760,HNRNPD-BGHLV22-26_17761	non-target-BGHLV22-1_17746,non-target-BGHLV22-2_17747	no clear band,no clear band	Released	ENCODE3
HNRNPD	K562	CRISPR			BGKcLV48-31,BGKcLV48-32	BGKcLV48-1,BGKcLV48-2		Experimented	ENCORE2
HNRNPD	HepG2	CRISPR			BGHcLV47-39,BGHcLV47-40	BGHcLV47-1,BGHcLV47-2	93.7,96.9	LibPreping	ENCORE2

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
HNRNPD	HNRNPD		Released	ENCODE3

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
HNRNPD	Product_ID: 12382 Lot_ID: 1 Source: Cell Signaling Technology Target Name: HNRNPD-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for HNRNPD is not avaliable on ENCORE database.

The binding motifs of HNRNPD

Proteins bound to RNA

HNRNPD RNA is bound by 47 proteins.

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eCLIP assay for HNRNPD is not avaliable on ENCORE database.

47 proteins are bound to HNRNPD RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr4	83275008	83275060	-	3'-UTR,intron-Distal	3.93904	400.00000	K562	PABPC4
chr4	83275271	83275324	-	3'-UTR,intron-Distal	4.46758	400.00000	K562	SF3B4
chr4	83275024	83275101	-	3'-UTR,intron-Distal	3.95218	400.00000	K562	FAM120A
chr4	83294980	83295065	-	5'-UTR,intron-Distal,intron-Proximal	4.79777	400.00000	K562	UCHL5
chr4	83295017	83295064	-	5'-UTR,intron-Distal,intron-Proximal	3.78577	400.00000	K562	DDX3X
chr4	83275324	83275362	-	intron-Distal	5.03633	400.00000	K562	SF3B4
chr4	83275269	83275326	-	3'-UTR,intron-Distal	5.06428	83.90518	K562	U2AF1
chr4	83275270	83275324	-	3'-UTR,intron-Distal	5.63119	82.50380	K562	U2AF2
chr4	83275060	83275098	-	3'-UTR,intron-Distal	3.24373	77.54771	K562	PABPC4
chr4	83295086	83295111	-	5'-UTR,intron-Distal,intron-Proximal	4.59634	74.69330	K562	DDX3X
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 187 entries

eCLIP assay for HNRNPD is not avaliable on ENCORE database.

Diffrential Expression

668 differentially expressed genes after Knockdown/Knockout HNRNPD protein.

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132 RBPs can affect the levels of HNRNPD.

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668 differentially expressed genes after Knockdown/Knockout HNRNPD protein :

Only display 100 entries as example. Please click "View All" button to see all 668 entries.

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Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CDH1	ENSG00000039068.14	1828.39470	665.58660	1.45780	21.86140	18.19960	HepG2	HNRNPD
SRCIN1	ENSG00000017373.11	480.85140	156.71950	1.61730	17.49160	13.97600	HepG2	HNRNPD
ACSL4	ENSG00000068366.15	8405.01680	17770.46420	-1.08020	14.99940	11.71790	HepG2	HNRNPD
KITLG	ENSG00000049130.9	80.58430	270.46260	-1.74690	14.71970	11.47290	HepG2	HNRNPD
RORA	ENSG00000069667.11	1043.27310	2172.82190	-1.05850	12.69760	9.60160	HepG2	HNRNPD
PCK2	ENSG00000100889.7	5477.65230	2810.56620	0.96260	11.62210	8.65930	HepG2	HNRNPD
MMP2	ENSG00000087245.8	132.86050	327.46670	-1.30140	10.19460	7.46130	HepG2	HNRNPD
MMP11	ENSG00000099953.5	2813.72470	1430.06730	0.97630	9.70890	7.03840	HepG2	HNRNPD
EDN1	ENSG00000078401.6	208.21590	497.64480	-1.25700	8.91420	6.35960	HepG2	HNRNPD
MAP3K9	ENSG00000006432.11	416.21770	787.66360	-0.92020	8.04100	5.57790	HepG2	HNRNPD
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

132 RBPs can affect the gene expression of HNRNPD :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
HNRNPD	ENSG00000138668.14	6017.49580	13201.65480	-1.13350	55.01770	51.46810	K562	HNRNPU
HNRNPD	ENSG00000138668.14	11919.89420	18260.44430	-0.61540	52.63170	50.08110	K562	NSUN2
HNRNPD	ENSG00000138668.14	2838.87040	5125.05640	-0.85230	39.02860	36.97920	HepG2	HNRNPU
HNRNPD	ENSG00000138668.14	1283.17100	4584.38690	-1.83700	37.19480	33.13510	HepG2	HNRNPD
HNRNPD	ENSG00000138668.14	5060.49840	9784.47150	-0.95120	31.96070	29.31120	K562	U2AF2
HNRNPD	ENSG00000138668.14	5172.91630	8207.28320	-0.66590	26.06400	24.34720	HepG2	AUH
HNRNPD	ENSG00000138668.14	3461.40770	5247.56950	-0.60030	25.86010	24.29510	HepG2	CKAP4
HNRNPD	ENSG00000138668.14	5766.53030	11807.16090	-1.03390	26.14430	23.51520	K562	GPKOW
HNRNPD	ENSG00000138668.14	4288.57260	7993.34110	-0.89830	23.64190	22.13080	HepG2	PUF60
HNRNPD	ENSG00000138668.14	2398.26190	4638.24180	-0.95160	23.63210	22.06390	HepG2	HNRNPA1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 178 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for HNRNPD is not available on ENCORE database.

70 RBPs can affect the splicing of HNRNPD :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	HNRNPD	ENSG00000138668.14	chr4	-	83292680	83292737	83280623	83280792	83294598	83295109	0.18400	0.00000	included	HepG2	G3BP1
SE	HNRNPD	ENSG00000138668.14	chr4	-	83277689	83277836	83276456	83276554	83277948	83278048	-0.34700	0.00000	excluded	K562	SRSF1
SE	HNRNPD	ENSG00000138668.14	chr4	-	83276047	83276154	83274986	83275307	83276456	83276554	0.07200	0.00001	included	K562	FTO
SE	HNRNPD	ENSG00000138668.14	chr4	-	83292680	83292737	83280696	83280792	83294598	83295109	0.15700	0.00091	included	HepG2	NKRF
SE	HNRNPD	ENSG00000138668.14	chr4	-	83277689	83277836	83276456	83276554	83277948	83278048	-0.13800	0.00008	excluded	K562	PRPF8
SE	HNRNPD	ENSG00000138668.14	chr4	-	83276047	83276154	83274986	83275307	83276456	83276554	0.23400	0.00000	included	HepG2	U2AF1
SE	HNRNPD	ENSG00000138668.14	chr4	-	83292680	83292737	83280623	83280792	83294598	83295139	-0.21600	0.00000	excluded	K562	AKAP8L
SE	HNRNPD	ENSG00000138668.14	chr4	-	83292680	83292737	83280623	83280792	83294598	83295139	0.14500	0.00000	included	K562	XRCC6
SE	HNRNPD	ENSG00000138668.14	chr4	-	83276047	83276154	83274986	83275307	83276456	83276554	0.07400	0.00000	included	K562	FMR1
SE	HNRNPD	ENSG00000138668.14	chr4	-	83292680	83292737	83280623	83280792	83294598	83295109	0.14500	0.00005	included	HepG2	HNRNPK

Showing 1 to 10 of 142 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

HNRNPD

General Information

Functions

Localization

Domains (AlphaFold: HNRNPD)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for HNRNPD is not avaliable on ENCORE database.

47 proteins are bound to HNRNPD RNA:

eCLIP assay for HNRNPD is not avaliable on ENCORE database.

Diffrential Expression

668 differentially expressed genes after Knockdown/Knockout HNRNPD protein :

132 RBPs can affect the gene expression of HNRNPD :

The Knockdown/knockout RNA-Seq assay for HNRNPD is not available on ENCORE database.

70 RBPs can affect the splicing of HNRNPD :

The Knockdown/knockout RNA-Seq assay for HNRNPD is not avaliable on ENCORE database.