PYGB

General Information

Gene Name       : PYGB
Gene ID             : ENSG00000100994.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PYGB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PYGBENSG00000100994.115.0311.828.43ENCSR000AEF
HepG2PYGBENSG00000100994.1162.5029.8946.20ENCSR985KAT
K562PYGBENSG00000100994.118.176.867.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PYGB is not avaliable on ENCORE database.



Proteins bound to RNA
  • PYGB RNA is bound by 19 proteins.  







eCLIP assay for PYGB is not avaliable on ENCORE database.





19 proteins are bound to PYGB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr202527727725277365+3'-UTR5.200598.05720K562UPF1
chr202527808025278142+3'-UTR4.647239.52232HepG2AKAP1
chr202527819025278245+3'-UTR5.552328.06720HepG2AKAP1
chr202527756825277619+3'-UTR4.444465.90082HepG2AKAP1
chr202527761925277692+3'-UTR3.955458.99663HepG2AKAP1
chr202527836825278429+3'-UTR5.7906313.33130HepG2UPF1
chr202527769225277736+3'-UTR5.6169610.52382HepG2AKAP1
chr202527837425278430+3'-UTR3.641696.84689K562UPF1
chr202527726225277325+3'-UTR6.1919416.65810HepG2UPF1
chr202527756025277623+3'-UTR5.1061517.11020HepG2UPF1
chr202527849525278585+3'-UTR6.2006515.41547HepG2UPF1
chr202527762325277735+3'-UTR5.2542625.66203HepG2UPF1
chr202527800925278080+3'-UTR6.0174313.43839HepG2AKAP1
chr202527800125278080+3'-UTR5.8591423.24562HepG2UPF1
chr202527787225277896+3'-UTR4.190133.69433K562UPF1
chr202527808025278137+3'-UTR4.8787212.82917HepG2UPF1
chr202527801025278090+3'-UTR3.770807.50442K562UPF1
chr202527735125277440+3'-UTR5.5277422.98045HepG2UPF1
chr202527775925277850+3'-UTR3.795036.97835HepG2AKAP1
chr202527722525277356+3'-UTR5.6631423.62966HepG2AKAP1
chr202527853425278594+3'-UTR4.306399.18836HepG2AKAP1
chr202527818925278254+3'-UTR6.5494119.49180HepG2UPF1
chr202527735625277459+3'-UTR3.759848.81477HepG2AKAP1
chr202526095025260976+CDS3.176534.51003HepG2PPIG
chr202525522725255247+CDS,intron-Proximal3.334644.99842HepG2PPIG
chr202526157125261623+CDS,intron-Proximal3.992547.26133HepG2PRPF8
chr202527321025273246+CDS3.375815.60389HepG2PPIG
chr202525796125258005+CDS,intron-Proximal4.077838.17589HepG2PRPF8
chr202525201825252061+CDS,intron-Proximal3.532729.28206HepG2PPIG
chr202526391225263918+CDS,intron-Proximal5.2064325.22330HepG2PRPF8
chr202526154125261621+CDS,intron-Proximal4.932626.04760K562AQR
chr202525210325252122+CDS3.091934.09741HepG2PPIG
chr202526471825264795+CDS,intron-Proximal3.374555.76569HepG2PRPF8
chr202526381125263871+CDS,intron-Proximal3.053529.88362HepG2PPIG
chr202526171825261794+CDS,intron-Proximal3.506067.35853HepG2PRPF8
chr202526103225261054+CDS,intron-Proximal3.9518710.32093HepG2PRPF8
chr202526381325263863+CDS3.919384.59151HepG2G3BP1
chr202524979925249843+CDS3.553849.91328HepG2PPIG
chr202527629825276347+CDS,intron-Proximal3.614046.34662HepG2PRPF8
chr202527305925273085+CDS4.042743.11282HepG2G3BP1
chr202522905325229096+CDS,intron-Proximal3.795885.43815HepG2PRPF8
chr202525532725255412+CDS,intron-Proximal4.275349.68077HepG2PRPF8
chr202526160625261683+CDS4.751764.25741HepG2G3BP1
chr202526102625261048+CDS3.249683.73413HepG2PPIG
chr202526104325261096+CDS,intron-Proximal4.952436.74224HepG2AQR
chr202527627025276298+CDS4.752895.27053HepG2PPIG
chr202526162025261673+CDS4.006067.83545HepG2PPIG
chr202526391225263957+CDS,intron-Proximal4.1580414.82829HepG2AQR
chr202526488225264922+CDS,intron-Proximal4.230267.79098HepG2PRPF8
chr202525788625257952+CDS3.2827710.14543HepG2PPIG
chr202527174225271774+intron-Distal4.310163.74177HepG2XRN2
chr202527330825273355+intron-Distal,intron-Proximal4.434115.67757HepG2CSTF2T
chr202527379825273865+intron-Distal3.232966.27493HepG2PRPF4
chr202527160225271684+intron-Distal3.983205.91072HepG2PCBP2
chr202527342325273500+intron-Distal3.390584.83431HepG2FAM120A
chr202526686225266958+intron-Distal3.153053.10883HepG2SUGP2
chr202525649525256547+intron-Distal4.106834.36329HepG2PRPF4
chr202527143225271525+intron-Distal3.414574.25955HepG2RBFOX2
chr202527427025274338+intron-Distal3.976993.65412HepG2HNRNPK
chr202525692625256984+intron-Distal3.903433.01994HepG2GTF2F1
chr202526105525261156+intron-Distal,intron-Proximal4.378175.61554HepG2EFTUD2
chr202525711825257199+intron-Distal,intron-Proximal4.317608.40143HepG2CSTF2T
chr202525714325257260+intron-Distal,intron-Proximal3.408216.45096HepG2PRPF4
chr202527165525271698+intron-Distal4.701693.97933HepG2DDX59
chr202526451225264635+intron-Distal5.021138.50262HepG2HNRNPK
chr202527355525273581+intron-Distal4.181953.13028HepG2FAM120A
chr202525585825255983+intron-Distal3.199496.24873HepG2CSTF2T
chr202527380025273856+intron-Distal3.849766.36044HepG2CSTF2T
chr202527173525271804+intron-Distal5.562937.82308HepG2DDX59
chr202527160825271699+intron-Distal4.829327.37084HepG2HNRNPK
chr202527354625273588+intron-Distal3.429114.37279HepG2CSTF2T
chr202525690125256953+intron-Distal4.184004.10323HepG2PRPF4
chr202527379425273855+intron-Distal3.635237.72902HepG2FAM120A
chr202527355025273599+intron-Distal3.768163.26022HepG2PRPF4
chr202527151825271608+intron-Distal3.042626.43015HepG2HNRNPK
chr202526366125263765+intron-Distal,intron-Proximal4.398414.10339HepG2CSTF2T
chr202527171525271803+intron-Distal4.946297.72290HepG2HNRNPK
chr202525672725256823+intron-Distal3.393936.45096HepG2PRPF4
chr202525674525256827+intron-Distal3.762708.15854HepG2CSTF2T
chr202525703925257113+intron-Distal4.861464.28089HepG2FAM120A
chr202525569825255759+intron-Distal4.664273.87340HepG2CSTF2T
chr202526104825261108+intron-Proximal5.708598.83608K562AQR
chr202527472825274790+intron-Proximal5.267617.50129HepG2SF3A3
chr202526105425261073+intron-Proximal4.6708113.14214HepG2PRPF8
chr202526391825263956+intron-Proximal5.4140531.25460HepG2PRPF8
chr202525193125252016+intron-Proximal4.496755.32775HepG2SF3B4
chr202527294925273007+intron-Proximal3.870983.01266HepG2SF3B4
chr202527472625274793+intron-Proximal3.646086.96502HepG2SF3B4
chr202526374625263804+intron-Proximal4.021563.56713HepG2SF3B4
chr202526394425263955+intron-Proximal5.7538911.25363K562AQR
chr202526107325261096+intron-Proximal6.1815616.30191HepG2PRPF8
chr202526899025269056+intron-Proximal4.234948.21012HepG2SF3B4
chr202526391325263934+intron-Proximal5.6882710.48996K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PYGB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PYGB is not available on ENCORE database.

  • 116 RBPs can affect the levels of PYGB.  








The Knockdown/knockout RNA-Seq assay for PYGB is not available on ENCORE database.





116 RBPs can affect the gene expression of PYGB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PYGBENSG00000100994.72734.812702153.439200.344702.857101.90070HepG2ABCF1
PYGBENSG00000100994.75256.345502106.112001.3194095.7698093.55340HepG2ACO1
PYGBENSG00000100994.75968.557302120.614601.4928018.1650016.92860HepG2AKAP1
PYGBENSG00000100994.72850.437701653.350100.785709.818007.99060HepG2AKAP8
PYGBENSG00000100994.72190.994201754.514300.320402.222001.51410HepG2ASCC1
PYGBENSG00000100994.75511.088503066.746000.8455036.2852034.29970HepG2AUH
PYGBENSG00000100994.72351.538601853.302400.343403.100802.47140HepG2BOP1
PYGBENSG00000100994.72594.280501666.946900.638007.824306.57430HepG2CIRBP
PYGBENSG00000100994.72422.377202105.668700.202002.739502.07670HepG2CKAP4
PYGBENSG00000100994.71254.787801701.43500-0.439304.050803.23330HepG2CPSF6
PYGBENSG00000100994.72254.389401773.591600.346003.499802.26080HepG2CPSF7
PYGBENSG00000100994.7761.456201159.38750-0.606505.034303.64210HepG2CSTF2
PYGBENSG00000100994.74993.053201888.819801.4023082.0787079.62060HepG2CELF1
PYGBENSG00000100994.71615.825201149.275300.491405.550303.96200HepG2DDX1
PYGBENSG00000100994.71864.310801325.538000.492005.611104.68000HepG2DDX21
PYGBENSG00000100994.75847.603302031.138801.5255039.9508037.85870HepG2DDX3X
PYGBENSG00000100994.76368.433601846.172301.7863030.3358028.22290HepG2DDX55
PYGBENSG00000100994.74713.840701745.377901.4333011.8192010.64920HepG2DDX6
PYGBENSG00000100994.71699.586001126.916700.5927010.921309.59990HepG2DNAJC21
PYGBENSG00000100994.71303.850901117.027800.223002.417801.80140HepG2DNAJC2
PYGBENSG00000100994.71860.643001243.538600.581206.137304.81470HepG2EEF2
PYGBENSG00000100994.71427.212401036.567000.461303.305102.09180HepG2EFTUD2
PYGBENSG00000100994.72692.112401677.290800.682508.343807.35250HepG2EIF2S1
PYGBENSG00000100994.72267.341901633.706300.472806.323004.62180HepG2EIF2S2
PYGBENSG00000100994.71480.203001009.410800.552204.825103.65620HepG2EIF3D
PYGBENSG00000100994.74632.555001805.007001.3597018.1631016.50660HepG2EIF4B
PYGBENSG00000100994.75051.124003521.090400.5205013.7371012.56160HepG2ETF1
PYGBENSG00000100994.73219.665602058.060500.6455011.376809.71240HepG2EWSR1
PYGBENSG00000100994.72780.764802174.494600.354702.718701.95650HepG2FIP1L1
PYGBENSG00000100994.71038.174301704.34620-0.715202.960901.90810HepG2FTO
PYGBENSG00000100994.73242.021101870.777400.7932011.5001010.18780HepG2FXR1
PYGBENSG00000100994.72245.525001734.971200.372002.186201.59210HepG2G3BP1
PYGBENSG00000100994.71438.49300898.730500.678507.872006.39560HepG2GEMIN5
PYGBENSG00000100994.71747.539501277.070800.452402.716001.70820HepG2GNB2L1
PYGBENSG00000100994.71609.171901040.838100.628504.443903.04000HepG2GRSF1
PYGBENSG00000100994.71605.89790950.888800.755904.384002.62540HepG2HNRNPA0
PYGBENSG00000100994.72602.838101866.341000.479809.538207.99930HepG2HNRNPA2B1
PYGBENSG00000100994.71346.13160973.908300.466902.851801.31130HepG2HNRNPD
PYGBENSG00000100994.72641.820101757.864200.587607.324906.22840HepG2HNRNPK
PYGBENSG00000100994.71307.905801840.60860-0.492904.678103.88050HepG2HNRNPLL
PYGBENSG00000100994.71772.306101257.148300.495405.468504.63820HepG2HNRNPU
PYGBENSG00000100994.73189.978901799.610900.825809.337107.15530HepG2HSPD1
PYGBENSG00000100994.74150.675101763.400501.2349027.4506025.59000HepG2IGF2BP2
PYGBENSG00000100994.71030.918101925.25940-0.9011034.0602031.13770HepG2KIF1C
PYGBENSG00000100994.73233.032102359.780700.454103.340102.42640HepG2LARP4
PYGBENSG00000100994.72086.695401251.597500.737308.220806.35800HepG2LARP7
PYGBENSG00000100994.73884.170501881.769701.0454016.9367015.47840HepG2MATR3
PYGBENSG00000100994.71974.221401056.393100.902008.265106.54150HepG2METAP2
PYGBENSG00000100994.72368.590601760.060100.428305.248404.16220HepG2MSI2
PYGBENSG00000100994.71228.194801877.16660-0.612003.852102.69690HepG2MTPAP
PYGBENSG00000100994.74358.751301925.983001.1782023.0315021.32160HepG2NCBP2
PYGBENSG00000100994.72333.195301705.549800.452002.726901.30870HepG2NKRF
PYGBENSG00000100994.7798.901201632.04660-1.0306017.5367015.84910HepG2NSUN2
PYGBENSG00000100994.72426.827401027.692001.239602.609801.75330HepG2PABPC1
PYGBENSG00000100994.71451.851801244.335800.222402.131901.38100HepG2PARN
PYGBENSG00000100994.72245.162001819.874500.302904.340803.61030HepG2PCBP1
PYGBENSG00000100994.71389.427001121.272200.309303.223402.43360HepG2PPIL4
PYGBENSG00000100994.7642.075901636.68140-1.3500050.0317047.65100HepG2PRPF4
PYGBENSG00000100994.71870.469501423.446600.393902.479801.71330HepG2PRPF8
PYGBENSG00000100994.72172.145301851.814600.230102.673702.13450HepG2PTBP1
PYGBENSG00000100994.73309.986701922.205200.7840016.2875015.00510HepG2PUF60
PYGBENSG00000100994.74318.915202040.621301.0816077.9291075.70680HepG2PUM1
PYGBENSG00000100994.72935.957902039.058900.525802.876102.19330HepG2PUM2
PYGBENSG00000100994.71265.710202145.21380-0.7612017.9414016.61900HepG2PUS1
PYGBENSG00000100994.73696.564401300.262901.507308.837407.62310HepG2RAVER1
PYGBENSG00000100994.75521.162502942.968400.9076022.0059020.82650HepG2RBM22
PYGBENSG00000100994.72145.259401509.301300.507202.323201.42240HepG2RBM27
PYGBENSG00000100994.73718.492402060.871700.8514032.0092030.59530HepG2NELFE
PYGBENSG00000100994.72357.473901919.458500.296404.235803.49450HepG2RECQL
PYGBENSG00000100994.71858.38660982.268900.9198018.2094016.83620HepG2RPS19
PYGBENSG00000100994.72411.687701391.839900.792909.280707.88600HepG2RPS2
PYGBENSG00000100994.71631.174401129.148000.530603.647402.72930HepG2RPS3A
PYGBENSG00000100994.72192.776301420.912800.625804.596803.19660HepG2RPS5
PYGBENSG00000100994.72158.327101408.012000.616204.491103.51700HepG2RRP9
PYGBENSG00000100994.7761.671801119.53400-0.555709.523008.43910HepG2SAFB2
PYGBENSG00000100994.73493.428702109.758300.727506.987405.88080HepG2SF3A3
PYGBENSG00000100994.72981.275101927.934400.6288017.3953016.10580HepG2SF3B4
PYGBENSG00000100994.72648.038701305.545301.0202052.8480050.71300HepG2SMN1
PYGBENSG00000100994.71488.153502027.11820-0.445902.446701.71310HepG2SNRNP70
PYGBENSG00000100994.75699.497403323.954000.7778036.9454035.66280HepG2SRFBP1
PYGBENSG00000100994.72567.497002012.364000.351406.214705.57580HepG2SRSF1
PYGBENSG00000100994.73787.998701898.036200.9968046.4506044.34360HepG2SRSF5
PYGBENSG00000100994.71908.989601637.180600.221502.586702.04960HepG2SRSF9
PYGBENSG00000100994.72519.013702885.94330-0.196202.468101.97800HepG2SSB
PYGBENSG00000100994.71630.73930982.283000.731206.737304.95490HepG2STIP1
PYGBENSG00000100994.73445.607002158.471400.674605.065804.26730HepG2SUCLG1
PYGBENSG00000100994.71277.301401808.84060-0.502007.700906.84190HepG2TAF15
PYGBENSG00000100994.72248.807601231.567600.8686010.203808.53040HepG2TFIP11
PYGBENSG00000100994.71964.916401232.479300.6728017.2826016.03220HepG2TRIM56
PYGBENSG00000100994.72452.987401878.101900.385202.781801.90630HepG2TUFM
PYGBENSG00000100994.72624.303001860.233500.496405.660404.77810HepG2U2AF1
PYGBENSG00000100994.72707.000301191.145901.184204.338103.09110HepG2U2AF2
PYGBENSG00000100994.73001.289201988.065500.594102.536701.73590HepG2UBE2L3
PYGBENSG00000100994.71783.772901085.398000.716607.313806.07240HepG2UCHL5
PYGBENSG00000100994.74062.467301806.408001.1691048.4047046.36120HepG2UTP3
PYGBENSG00000100994.72151.857601430.648100.588802.592801.57160HepG2XRCC6
PYGBENSG00000100994.74103.633802057.777700.9957047.9893046.43810HepG2ZNF622
PYGBENSG00000100994.7406.43390599.57730-0.560904.842604.12610K562AGGF1
PYGBENSG00000100994.7442.61110618.90540-0.483703.338902.70620K562AQR
PYGBENSG00000100994.7437.70270274.770500.671605.029103.31540K562CIRBP
PYGBENSG00000100994.7575.86130416.079400.468803.805602.50060K562CPEB4
PYGBENSG00000100994.7431.49110327.245700.398902.296801.35160K562DDX3X
PYGBENSG00000100994.7738.53580430.581300.7783011.8114010.56650K562DDX47
PYGBENSG00000100994.71289.81240519.425901.3121037.6089035.56990K562EIF2S2
PYGBENSG00000100994.7339.05580200.685800.756504.823703.69280K562FMR1
PYGBENSG00000100994.752.76760141.32790-1.421305.175104.13980K562G3BP2
PYGBENSG00000100994.7285.82240188.276700.602203.129602.28820K562GPKOW
PYGBENSG00000100994.7371.85760275.721500.431402.147701.61330K562HNRNPC
PYGBENSG00000100994.7948.07330426.366801.1528017.7579015.87450K562HSPD1
PYGBENSG00000100994.7604.83330256.422801.2379013.0384010.31200K562IGF2BP2
PYGBENSG00000100994.7360.33300260.796000.466302.709301.53270K562IGF2BP3
PYGBENSG00000100994.7404.18290662.07830-0.712003.271602.36700K562KIF1C
PYGBENSG00000100994.7380.66000269.439000.498403.232402.31680K562MAGOH
PYGBENSG00000100994.7354.39640268.884600.398302.107001.31160K562MATR3
PYGBENSG00000100994.7287.17880183.783900.643803.580502.57700K562METAP2
PYGBENSG00000100994.7470.03650341.401300.461203.045601.75640K562NCBP2
PYGBENSG00000100994.7377.28670263.400000.518303.371501.87790K562PCBP1
PYGBENSG00000100994.7381.91190618.66920-0.695905.526704.79070K562PUS1
PYGBENSG00000100994.7433.27520602.85370-0.476503.682803.01290K562RBM15
PYGBENSG00000100994.7397.28970250.988400.662504.826803.67940K562RBM22
PYGBENSG00000100994.7367.32900244.687200.586003.444401.84060K562RBM34
PYGBENSG00000100994.7446.69230281.463900.666203.900502.92880K562RPS19
PYGBENSG00000100994.7270.28580180.053700.586002.362001.44580K562RPS3
PYGBENSG00000100994.7581.99800340.126000.774802.646201.48140K562SF1
PYGBENSG00000100994.7258.24360146.878300.814005.499904.26780K562SF3B4
PYGBENSG00000100994.7410.02610256.638100.675904.995304.04790K562SRSF1
PYGBENSG00000100994.7257.31230173.809900.565902.495601.50370K562SRSF4
PYGBENSG00000100994.7403.17230242.389600.734003.824802.55330K562SRSF5
PYGBENSG00000100994.7442.00760250.534500.819007.561606.10600K562TIA1
PYGBENSG00000100994.7410.45290245.878300.739205.491003.83290K562TRA2A
PYGBENSG00000100994.7602.92680493.656600.288401.936601.32760K562UPF1
PYGBENSG00000100994.7584.31190328.177300.832206.801904.95620K562UTP3
PYGBENSG00000100994.7522.95610697.28900-0.415103.086602.17150K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PYGB is not available on ENCORE database.





1 RBPs can affect the splicing of PYGB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPYGBENSG00000100994.7chr20+2526866325268861252647392526488725269060252691190.120000.005900.07058includedK562PUS1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PYGB is not avaliable on ENCORE database.