PPP1R12B

General Information

Gene Name       : PPP1R12B
Gene ID             : ENSG00000077157.21
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PPP1R12B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPP1R12BENSG00000077157.211.333.422.38ENCSR000AEF
HepG2PPP1R12BENSG00000077157.215.085.175.12ENCSR985KAT
K562PPP1R12BENSG00000077157.216.989.418.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPP1R12B is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPP1R12B RNA is bound by 16 proteins.  







eCLIP assay for PPP1R12B is not avaliable on ENCORE database.





16 proteins are bound to PPP1R12B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1202406938202407017+3'-UTR,CDS,intron-Proximal4.211233.44423K562BUD13
chr1202396236202396290+3'-UTR,CDS3.752115.14848K562ZNF622
chr1202396270202396313+3'-UTR,CDS,intron-Proximal4.468965.64870K562DDX24
chr1202396220202396270+3'-UTR,CDS3.850443.04209K562DDX24
chr1202400668202400709+3'-UTR,CDS4.305324.43680K562ZNF622
chr1202549602202549698+3'-UTR,CDS4.319363.71570HepG2BCLAF1
chr1202394779202394832+3'-UTR,CDS,intron-Distal4.819615.24929K562ZNF622
chr1202407092202407149+3'-UTR,CDS3.241323.12941K562UCHL5
chr1202397979202398054+3'-UTR,CDS,intron-Proximal3.788643.38114HepG2GRWD1
chr1202397982202398014+3'-UTR,CDS,intron-Proximal5.370766.53290K562DDX24
chr1202397979202398045+3'-UTR,CDS,intron-Proximal5.548049.57229K562ZNF622
chr1202400621202400715+3'-UTR,CDS3.471834.22563K562UCHL5
chr1202396203202396310+3'-UTR,CDS3.117364.30396K562UCHL5
chr1202396290202396315+3'-UTR,CDS,intron-Proximal4.395614.43680K562ZNF622
chr1202394707202394824+3'-UTR,CDS,intron-Distal3.223928.23663HepG2BCLAF1
chr1202396207202396313+3'-UTR,CDS,intron-Proximal3.354963.32039HepG2PPIG
chr1202397977202398059+3'-UTR,CDS,intron-Proximal4.108447.66928K562BUD13
chr1202394726202394830+3'-UTR,CDS,intron-Distal4.4250311.52509K562DDX24
chr1202394766202394828+3'-UTR,CDS,intron-Distal3.453163.64266HepG2PPIG
chr1202398041202398058+3'-UTR,CDS,intron-Proximal4.870763.02297K562DDX24
chr1202462295202462398+5'-UTR,CDS3.831785.77244K562UCHL5
chr1202317968202318061+5'-UTR,CDS3.304503.50696K562BUD13
chr1202317939202318011+5'-UTR,CDS4.265163.84644HepG2NCBP2
chr1202462262202462382+5'-UTR,CDS3.571697.59700K562ZNF622
chr1202317847202317901+5'-UTR3.436843.61259K562ZNF622
chr1202385914202386027+CDS,intron-Proximal4.586589.08097K562DDX24
chr1202465908202465950+CDS,intron-Proximal4.387074.10264K562ZNF622
chr1202391835202391904+CDS,intron-Distal,intron-Proximal3.302115.04943K562ZNF622
chr1202317980202318123+CDS4.308414.50440HepG2PPIG
chr1202385918202386039+CDS3.716299.25079K562ZNF622
chr1202411568202411656+CDS,intron-Proximal4.869946.64445K562BUD13
chr1202465905202465963+CDS,intron-Proximal3.588684.97821K562BUD13
chr1202538273202538319+CDS,intron-Proximal4.344554.72838K562UCHL5
chr1202411581202411704+CDS,intron-Proximal3.315895.91405HepG2BCLAF1
chr1202317995202318104+CDS3.485846.18248K562UCHL5
chr1202385941202386059+CDS,intron-Proximal3.950114.17155HepG2BCLAF1
chr1202464700202464813+CDS,intron-Proximal4.6965310.62290K562ZNF622
chr1202411585202411662+CDS3.783793.14999HepG2GRWD1
chr1202536905202536960+CDS,intron-Proximal4.573673.20743HepG2PPIG
chr1202536915202536958+CDS3.292393.07653K562ZNF622
chr1202544064202544131+CDS,intron-Distal,intron-Proximal5.024605.39854K562PTBP1
chr1202385931202386036+CDS3.623684.80912HepG2PPIG
chr1202538273202538314+CDS,intron-Proximal3.202103.07653K562ZNF622
chr1202411699202411717+CDS,intron-Proximal6.4939912.64691K562AQR
chr1202536910202536959+CDS4.120823.36385K562UCHL5
chr1202531892202531956+CDS,intron-Proximal3.873053.25055K562U2AF2
chr1202413871202413938+intron-Distal3.978053.76275K562PTBP1
chr1202413836202413932+intron-Distal4.133076.57428HepG2PTBP1
chr1202457451202457612+intron-Distal,intron-Proximal3.950013.66668K562KHSRP
chr1202366270202366354+intron-Distal4.899074.90095K562PTBP1
chr1202414173202414323+intron-Distal,intron-Proximal3.527724.48818HepG2GRWD1
chr1202318357202318402+intron-Distal,intron-Proximal3.929143.45860K562TIA1
chr1202366241202366346+intron-Distal4.083304.03269HepG2PTBP1
chr1202412187202412236+intron-Distal,intron-Proximal3.884255.83621K562AQR
chr1202350544202350623+intron-Distal4.525693.72755K562EIF4G2
chr1202542511202542599+intron-Distal4.356087.59321K562PTBP1
chr1202491765202491897+intron-Distal3.828453.34600K562SAFB
chr1202507969202508045+intron-Distal4.118494.07628HepG2PTBP1
chr1202507957202508072+intron-Distal5.245157.91717K562PTBP1
chr1202394591202394659+intron-Distal,intron-Proximal3.334354.96160K562KHSRP
chr1202366478202366547+intron-Distal4.461843.55787K562PTBP1
chr1202411749202411805+intron-Distal,intron-Proximal4.342336.48405K562AQR
chr1202394290202394381+intron-Distal4.147513.42844K562KHSRP
chr1202322740202322814+intron-Distal3.813613.22972K562TARDBP
chr1202411717202411749+intron-Proximal6.7601416.44435K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPP1R12B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPP1R12B is not available on ENCORE database.

  • 85 RBPs can affect the levels of PPP1R12B.  








The Knockdown/knockout RNA-Seq assay for PPP1R12B is not available on ENCORE database.





85 RBPs can affect the gene expression of PPP1R12B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPP1R12BENSG00000077157.16586.26380810.86080-0.467903.022801.93650HepG2AKAP8
PPP1R12BENSG00000077157.16240.57620420.03170-0.804005.705804.60140HepG2ASCC1
PPP1R12BENSG00000077157.16281.99160485.00940-0.782404.699203.47820HepG2BCCIP
PPP1R12BENSG00000077157.16249.98410521.81170-1.0617011.3226010.22070HepG2BOP1
PPP1R12BENSG00000077157.16372.29540614.99410-0.7241010.246709.13300HepG2CKAP4
PPP1R12BENSG00000077157.16446.42070633.67460-0.505304.937804.12410HepG2CELF1
PPP1R12BENSG00000077157.16829.14670681.372700.283102.639801.91260HepG2DAZAP1
PPP1R12BENSG00000077157.16435.48470568.89600-0.385503.523902.59670HepG2DDX19B
PPP1R12BENSG00000077157.16363.03940486.27910-0.421702.112101.55830HepG2DDX3X
PPP1R12BENSG00000077157.16320.87440530.87670-0.726407.893306.75510HepG2DNAJC21
PPP1R12BENSG00000077157.16432.04710526.18330-0.284402.018301.44460HepG2DNAJC2
PPP1R12BENSG00000077157.16542.45630401.567300.433802.335901.78840HepG2EIF2S1
PPP1R12BENSG00000077157.16658.01700443.768800.568203.810903.06600HepG2EIF4A3
PPP1R12BENSG00000077157.16442.35480601.08800-0.442403.204202.30690HepG2EWSR1
PPP1R12BENSG00000077157.16435.26670281.975100.626204.403003.42490HepG2FUBP3
PPP1R12BENSG00000077157.16603.68740447.775200.430902.478201.82270HepG2FXR1
PPP1R12BENSG00000077157.16435.26040684.03820-0.652203.918802.59480HepG2GRSF1
PPP1R12BENSG00000077157.16445.48930640.01670-0.522702.909901.35260HepG2HNRNPD
PPP1R12BENSG00000077157.16595.59210883.12650-0.568303.807402.36320HepG2HSPD1
PPP1R12BENSG00000077157.16391.66540562.29820-0.521705.616804.17900HepG2KIF1C
PPP1R12BENSG00000077157.16577.51330882.32540-0.611503.925802.43060HepG2KRR1
PPP1R12BENSG00000077157.16328.07270450.43360-0.457302.133401.57530HepG2MATR3
PPP1R12BENSG00000077157.16272.34530436.50810-0.680602.855101.78490HepG2METAP2
PPP1R12BENSG00000077157.16756.98630537.829500.493003.879002.92470HepG2MSI2
PPP1R12BENSG00000077157.16535.82140754.63400-0.494004.217702.23660HepG2NUP35
PPP1R12BENSG00000077157.16413.24990586.19490-0.504404.819003.73750HepG2PARN
PPP1R12BENSG00000077157.16589.44470857.56120-0.540903.672901.61920HepG2PPIG
PPP1R12BENSG00000077157.16418.53310528.20980-0.335802.249901.57850HepG2PPIL4
PPP1R12BENSG00000077157.16887.64740377.171301.2347028.3809026.98660HepG2PTBP1
PPP1R12BENSG00000077157.16515.96590644.95940-0.321901.914501.40550HepG2PUF60
PPP1R12BENSG00000077157.16508.90020684.64730-0.428004.731303.99930HepG2PUM1
PPP1R12BENSG00000077157.16585.61750408.436900.519704.401103.63950HepG2QKI
PPP1R12BENSG00000077157.16593.97420853.10300-0.522305.306304.16510HepG2RBM15
PPP1R12BENSG00000077157.16468.33130682.92460-0.544205.599004.92740HepG2RBM22
PPP1R12BENSG00000077157.16689.73020370.701200.8957011.251609.95220HepG2RBM25
PPP1R12BENSG00000077157.16320.17200584.46860-0.868307.627805.97190HepG2RBM27
PPP1R12BENSG00000077157.16583.13360419.736400.474204.005803.37650HepG2NELFE
PPP1R12BENSG00000077157.16569.87110390.962000.543505.204604.39380HepG2RECQL
PPP1R12BENSG00000077157.16365.76480546.91540-0.580402.922301.95400HepG2RPS10
PPP1R12BENSG00000077157.16237.34070405.80780-0.773806.287605.40200HepG2RPS19
PPP1R12BENSG00000077157.16392.76220742.32900-0.918407.746206.42580HepG2RPS3A
PPP1R12BENSG00000077157.16384.97050550.23630-0.515303.090501.95030HepG2RPS5
PPP1R12BENSG00000077157.16429.06440527.39570-0.297702.035101.46950HepG2SAFB2
PPP1R12BENSG00000077157.16502.79830699.02050-0.475402.684201.39240HepG2SART3
PPP1R12BENSG00000077157.16287.17750407.31480-0.504202.740301.80640HepG2SERBP1
PPP1R12BENSG00000077157.16562.98430392.642900.519804.471903.74720HepG2SF3B4
PPP1R12BENSG00000077157.16403.21820615.03440-0.609107.788506.79380HepG2SMN1
PPP1R12BENSG00000077157.16370.59890567.67030-0.615203.680802.56360HepG2SMNDC1
PPP1R12BENSG00000077157.16326.47060570.74560-0.805904.712603.68120HepG2SNRNP70
PPP1R12BENSG00000077157.16584.10100409.850900.511004.740204.16370HepG2SRSF1
PPP1R12BENSG00000077157.16837.79000551.936200.602004.154802.90290HepG2SRSF3
PPP1R12BENSG00000077157.16494.22860636.79680-0.365703.010302.35980HepG2SRSF5
PPP1R12BENSG00000077157.16412.43720333.450000.306601.906101.43210HepG2SRSF9
PPP1R12BENSG00000077157.16815.81480669.663500.284702.379501.89640HepG2SSB
PPP1R12BENSG00000077157.16642.35870879.63620-0.453502.887101.57830HepG2SSRP1
PPP1R12BENSG00000077157.16454.88510645.88640-0.505802.898901.76960HepG2STIP1
PPP1R12BENSG00000077157.16584.73600368.436600.666307.116406.28900HepG2TAF15
PPP1R12BENSG00000077157.16514.55950338.493600.604103.365802.44850HepG2TIA1
PPP1R12BENSG00000077157.16354.08240580.59230-0.713409.014208.08710HepG2TRIM56
PPP1R12BENSG00000077157.16417.18210630.08890-0.594905.262504.01800HepG2TUFM
PPP1R12BENSG00000077157.16496.63890748.80610-0.592407.918106.83630HepG2UPF1
PPP1R12BENSG00000077157.16578.47060769.68780-0.412003.918402.69360HepG2UTP18
PPP1R12BENSG00000077157.16575.25980722.94690-0.329702.686102.09590HepG2UTP3
PPP1R12BENSG00000077157.16457.62210664.92890-0.539002.999701.85310HepG2XPO5
PPP1R12BENSG00000077157.16331.59630467.31170-0.495002.283901.61980HepG2XRN2
PPP1R12BENSG00000077157.16628.85200823.54710-0.389104.600003.94070HepG2ZNF622
PPP1R12BENSG00000077157.161608.421902024.26370-0.331804.597303.89790K562AGGF1
PPP1R12BENSG00000077157.161756.806802106.34080-0.261801.906901.36040K562AKAP8L
PPP1R12BENSG00000077157.161364.140601750.32190-0.359603.188701.85570K562APOBEC3C
PPP1R12BENSG00000077157.161811.381302210.06370-0.287003.147402.16980K562ATP5C1
PPP1R12BENSG00000077157.161976.111902419.09720-0.291802.845501.64910K562CCDC124
PPP1R12BENSG00000077157.161447.062101696.17130-0.229202.421601.80650K562DDX47
PPP1R12BENSG00000077157.161232.12730975.116300.337402.671301.86520K562EIF4A3
PPP1R12BENSG00000077157.161284.54140997.907300.364202.690401.84840K562FMR1
PPP1R12BENSG00000077157.16745.453501014.08340-0.444005.004904.22560K562FXR1
PPP1R12BENSG00000077157.16953.985501346.72800-0.497405.265404.21760K562GRSF1
PPP1R12BENSG00000077157.161020.904301594.49600-0.643307.834406.51380K562HSPD1
PPP1R12BENSG00000077157.16910.173301153.55460-0.341902.813501.96610K562MAGOH
PPP1R12BENSG00000077157.16818.218801151.20300-0.492605.360004.01790K562MATR3
PPP1R12BENSG00000077157.16519.12000752.65760-0.535903.736002.18140K562NONO
PPP1R12BENSG00000077157.161851.959501254.629200.561705.355304.19380K562PCBP3
PPP1R12BENSG00000077157.161390.62310962.366900.531006.929605.66990K562POLR2G
PPP1R12BENSG00000077157.16861.862301335.08280-0.631407.224505.77800K562PPIG
PPP1R12BENSG00000077157.16462.52170743.64410-0.685105.863004.76910K562PRPF8
PPP1R12BENSG00000077157.161529.934601120.756100.448905.185804.30050K562PTBP1
PPP1R12BENSG00000077157.161570.543302164.29490-0.462604.651903.59700K562PUF60
PPP1R12BENSG00000077157.161882.921302255.56960-0.260502.822401.85380K562PUM2
PPP1R12BENSG00000077157.161479.821502088.89270-0.497305.069204.36240K562PUS1
PPP1R12BENSG00000077157.161552.524902035.32730-0.390605.012604.23600K562RBM15
PPP1R12BENSG00000077157.16852.644401074.63040-0.333802.412601.63140K562RBM22
PPP1R12BENSG00000077157.16524.80550757.58050-0.529603.460602.54400K562RPS19
PPP1R12BENSG00000077157.161610.703501302.123100.306703.562202.64430K562SF3A3
PPP1R12BENSG00000077157.161887.868301334.057500.5008011.066409.34610K562SRPK2
PPP1R12BENSG00000077157.16835.277801098.72300-0.395503.549602.75620K562SRSF1
PPP1R12BENSG00000077157.16731.73310965.24660-0.399603.643102.70170K562SYNCRIP
PPP1R12BENSG00000077157.161483.170101197.219300.308902.655101.79480K562WDR3
PPP1R12BENSG00000077157.161525.034901244.997300.292603.870502.88040K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPP1R12B is not available on ENCORE database.





9 RBPs can affect the splicing of PPP1R12B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPP1R12BENSG00000077157.16chr1+202414173202414356202411653202411700202418116202418225-0.399000.001180.02353excludedHepG2U2AF1
SEPPP1R12BENSG00000077157.16chr1+202399858202399938202397982202398057202400607202400747-0.224000.009010.09723excludedK562PUS1
SEPPP1R12BENSG00000077157.16chr1+2024141732024143562024116532024117002024181162024182250.224000.000300.02568includedK562HNRNPL
SEPPP1R12BENSG00000077157.16chr1+202414173202414356202411653202411700202418116202418225-0.233000.000720.02674excludedK562UTP18
SEPPP1R12BENSG00000077157.16chr1+202414173202414356202411653202411700202418116202418225-0.508000.000000.00007excludedK562U2AF2
SEPPP1R12BENSG00000077157.16chr1+202414173202414356202411653202411700202418116202418225-0.412000.000000.00002excludedK562AGGF1
SEPPP1R12BENSG00000077157.16chr1+2024141732024143562024116532024117002024181162024182250.171000.000310.01626includedK562SF3B1
SEPPP1R12BENSG00000077157.16chr1+202412214202412255202411653202411700202418116202418225-0.762000.002900.08934excludedK562PTBP1
SEPPP1R12BENSG00000077157.16chr1+2024171702024172322024141732024143562024181162024182990.523000.000000.00000includedK562HNRNPC
MXEPPP1R12BENSG00000077157.16chr1+202385914202386045202391747202391866202317826202318270202394693202394853-0.379000.005320.073502includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPP1R12B is not avaliable on ENCORE database.