HYAL2

General Information

Gene Name       : HYAL2
Gene ID             : ENSG00000068001.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HYAL2)


Antibody Validation


Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HYAL2ENSG00000068001.130.554.332.44ENCSR000AEF
HepG2HYAL2ENSG00000068001.1398.3728.6363.50ENCSR985KAT
K562HYAL2ENSG00000068001.139.466.888.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HYAL2 is not avaliable on ENCORE database.



Proteins bound to RNA

  • HYAL2 RNA is bound by 8 proteins.  







eCLIP assay for HYAL2 is not avaliable on ENCORE database.





8 proteins are bound to HYAL2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr35035532650355407-3'-UTR,intron-Distal3.182376.74417HepG2LARP4
chr35035789750357968-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.7214687.02682HepG2DDX3X
chr35035542550355475-3'-UTR,intron-Distal3.051005.39571HepG2LARP4
chr35035547550355620-3'-UTR,CDS,intron-Distal4.7772418.46784HepG2LARP4
chr35035791150358018-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.9738534.45064HepG2BUD13
chr35035794150358031-3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.285725.56912HepG2AQR
chr35035879550358900-5'-UTR,intron-Distal,intron-Proximal6.93113400.00000HepG2DDX3X
chr35035870650358776-5'-UTR,intron-Distal,intron-Proximal5.1600718.95513HepG2BUD13
chr35035584450355888-CDS,intron-Distal3.486683.93340HepG2LIN28B
chr35035720750357281-CDS,intron-Distal3.403633.94213HepG2LIN28B
chr35035558950355670-CDS,intron-Distal4.893914.13513HepG2LIN28B
chr35035740050357464-CDS,intron-Distal,intron-Proximal4.259214.12428HepG2SND1
chr35035756350357588-CDS,intron-Distal,intron-Proximal4.261354.39452HepG2YBX3
chr35035782350357897-CDS,intron-Distal6.7095970.67606HepG2DDX3X
chr35035741550357508-CDS,intron-Distal,intron-Proximal5.291324.90304HepG2RPS3
chr35035562050355702-CDS,intron-Distal3.282976.69895HepG2LARP4
chr35035765250357690-CDS,intron-Distal,intron-Proximal4.421483.77218HepG2SND1
chr35035775650357823-CDS,intron-Distal,intron-Proximal5.4204945.59655HepG2DDX3X
chr35035733350357382-CDS,intron-Distal,intron-Proximal4.791224.06516HepG2SND1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HYAL2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HYAL2 is not available on ENCORE database.

  • 92 RBPs can affect the levels of HYAL2.  








The Knockdown/knockout RNA-Seq assay for HYAL2 is not available on ENCORE database.





92 RBPs can affect the gene expression of HYAL2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HYAL2ENSG00000068001.91380.803001818.49000-0.397202.858001.90130HepG2ABCF1
HYAL2ENSG00000068001.91936.160401343.644100.5269011.8963010.82400HepG2ACO1
HYAL2ENSG00000068001.9588.75570769.42830-0.386102.486401.54030HepG2ADAR
HYAL2ENSG00000068001.92528.342801694.131200.577505.167604.46960HepG2AKAP1
HYAL2ENSG00000068001.91906.912701301.947200.550503.379502.23690HepG2AKAP8
HYAL2ENSG00000068001.9875.757701401.65320-0.678504.242903.27910HepG2ASCC1
HYAL2ENSG00000068001.91533.975701029.471800.575302.992702.01440HepG2BCCIP
HYAL2ENSG00000068001.92459.338501841.837500.417002.702101.74060HepG2CCAR1
HYAL2ENSG00000068001.9722.232901331.69880-0.882706.254305.12140HepG2CIRBP
HYAL2ENSG00000068001.91686.252501343.165300.328105.178504.32010HepG2CKAP4
HYAL2ENSG00000068001.91351.34640856.971600.657004.135403.19300HepG2CNOT7
HYAL2ENSG00000068001.91979.224601170.609000.7576019.1160017.73390HepG2CELF1
HYAL2ENSG00000068001.91445.551701258.596300.199702.204001.53100HepG2DAZAP1
HYAL2ENSG00000068001.91065.182001242.59240-0.222302.270601.50980HepG2DDX19B
HYAL2ENSG00000068001.9528.71040878.01040-0.731803.227402.23950HepG2DDX24
HYAL2ENSG00000068001.92102.748301622.639000.373802.362301.77970HepG2DDX3X
HYAL2ENSG00000068001.91692.917901012.274400.741803.897702.99490HepG2DDX55
HYAL2ENSG00000068001.91115.663401513.81040-0.440303.878602.68860HepG2DDX5
HYAL2ENSG00000068001.92119.031201394.376300.603705.574204.72430HepG2DDX6
HYAL2ENSG00000068001.9790.413701285.45500-0.701607.981206.94410HepG2DKC1
HYAL2ENSG00000068001.91433.07370774.780500.8872010.497509.19800HepG2DNAJC21
HYAL2ENSG00000068001.91146.64150767.930900.5783011.4048010.17990HepG2DNAJC2
HYAL2ENSG00000068001.92144.762101339.955600.678507.948406.97950HepG2EIF2S1
HYAL2ENSG00000068001.91135.591201480.57040-0.382702.513801.90340HepG2EIF4A3
HYAL2ENSG00000068001.9714.973901241.76500-0.7964016.0174014.34730HepG2EIF4G1
HYAL2ENSG00000068001.91216.833901574.92920-0.372203.427102.21720HepG2ESF1
HYAL2ENSG00000068001.93652.674701836.126800.9922013.8913012.37300HepG2FIP1L1
HYAL2ENSG00000068001.91847.649001494.553900.305901.955001.36900HepG2FXR1
HYAL2ENSG00000068001.91072.284301386.03890-0.370302.107501.52370HepG2G3BP1
HYAL2ENSG00000068001.91343.32800860.100100.643102.577901.59860HepG2GNB2L1
HYAL2ENSG00000068001.91765.097501282.682200.460503.114402.08100HepG2HDGF
HYAL2ENSG00000068001.91222.42450870.053600.490501.963601.36860HepG2HNRNPC
HYAL2ENSG00000068001.91054.73680742.344100.506603.116901.50970HepG2HNRNPD
HYAL2ENSG00000068001.91814.637501146.455900.6624019.5678017.92640HepG2HNRNPL
HYAL2ENSG00000068001.91453.04950864.301500.749409.259008.19860HepG2HNRNPU
HYAL2ENSG00000068001.91064.477701483.58250-0.478905.391004.41300HepG2IGF2BP1
HYAL2ENSG00000068001.9900.620301408.74340-0.645403.866803.08090HepG2IGF2BP2
HYAL2ENSG00000068001.91160.07730817.130800.505503.445802.08930HepG2KHDRBS1
HYAL2ENSG00000068001.92661.025401945.972700.451403.157802.26770HepG2LARP4
HYAL2ENSG00000068001.91389.15070843.108700.720303.360802.11020HepG2LARP7
HYAL2ENSG00000068001.91045.776201495.07890-0.515603.594502.84610HepG2MAGOH
HYAL2ENSG00000068001.92167.696101503.329500.527904.111803.35700HepG2MATR3
HYAL2ENSG00000068001.9835.667801360.44270-0.703104.565703.29790HepG2MTPAP
HYAL2ENSG00000068001.92058.675001538.646000.420003.220202.53940HepG2NCBP2
HYAL2ENSG00000068001.92318.343401248.026600.8933023.3065021.25210HepG2NOL12
HYAL2ENSG00000068001.9740.31480438.213700.756404.581702.75100HepG2NOLC1
HYAL2ENSG00000068001.91431.86000929.983400.622502.574001.52380HepG2NONO
HYAL2ENSG00000068001.9862.944501182.74960-0.454803.775202.90360HepG2NSUN2
HYAL2ENSG00000068001.91103.03000783.446800.493502.276601.48570HepG2PABPC1
HYAL2ENSG00000068001.91699.22060855.513900.9899012.6461011.04850HepG2PARN
HYAL2ENSG00000068001.91176.69240770.888400.610009.565108.23820HepG2PPIL4
HYAL2ENSG00000068001.92153.493901264.730500.7677012.5224011.45370HepG2PUM1
HYAL2ENSG00000068001.92042.440301263.787400.6924013.2410011.83910HepG2PUM2
HYAL2ENSG00000068001.91148.528601368.56130-0.252902.776802.15990HepG2PUS1
HYAL2ENSG00000068001.9661.43790418.685000.659604.742502.41040HepG2RBM14
HYAL2ENSG00000068001.91604.450301016.733600.658002.235101.35290HepG2RBM27
HYAL2ENSG00000068001.91338.273401631.72760-0.286003.095802.53010HepG2NELFE
HYAL2ENSG00000068001.9734.187501622.72750-1.1442020.2249018.72180HepG2RPLP0
HYAL2ENSG00000068001.91234.15140899.948700.455502.652502.04930HepG2RPS19
HYAL2ENSG00000068001.91164.01660769.700300.5966011.132109.97590HepG2SAFB2
HYAL2ENSG00000068001.9921.529901320.24050-0.518705.156204.21510HepG2SF3B1
HYAL2ENSG00000068001.91449.578301142.408700.343505.289904.37150HepG2SLBP
HYAL2ENSG00000068001.91760.24370897.603300.9715037.4552035.56870HepG2SMN1
HYAL2ENSG00000068001.91424.44970793.649600.843702.682001.74130HepG2SMNDC1
HYAL2ENSG00000068001.91917.885702253.11380-0.232403.292702.76080HepG2SRFBP1
HYAL2ENSG00000068001.91341.947201593.30880-0.247702.506102.05050HepG2SRSF1
HYAL2ENSG00000068001.92337.381001176.348600.9905036.7526034.83960HepG2SRSF5
HYAL2ENSG00000068001.91230.897001480.12350-0.266002.185101.55800HepG2SRSF7
HYAL2ENSG00000068001.9902.798801956.16260-1.1155042.7414041.30780HepG2SSB
HYAL2ENSG00000068001.92763.442201337.800601.0465050.8419048.77740HepG2SUCLG1
HYAL2ENSG00000068001.9759.414701007.56370-0.407902.067901.47060HepG2SUPV3L1
HYAL2ENSG00000068001.9977.020401432.24160-0.551803.989903.33540HepG2TAF15
HYAL2ENSG00000068001.91053.94770675.249400.642205.040103.75520HepG2TFIP11
HYAL2ENSG00000068001.91740.22500847.337301.0382035.3232033.59410HepG2TRIM56
HYAL2ENSG00000068001.92012.630701163.975700.789905.916504.57430HepG2TUFM
HYAL2ENSG00000068001.91196.052901570.40730-0.392903.421902.72870HepG2U2AF1
HYAL2ENSG00000068001.91563.321701247.428300.325604.470503.61830HepG2UPF1
HYAL2ENSG00000068001.91566.792601204.336500.379504.858804.10190HepG2UTP3
HYAL2ENSG00000068001.91178.13940771.287600.611104.336002.95850HepG2XPO5
HYAL2ENSG00000068001.9571.361201096.89710-0.9410023.7201022.10150HepG2ZC3H8
HYAL2ENSG00000068001.91600.915401371.926300.222602.102201.60700HepG2ZNF622
HYAL2ENSG00000068001.9302.48800195.763600.627703.389902.01930K562ABCF1
HYAL2ENSG00000068001.9175.16410124.072600.497401.929601.38010K562AKAP8L
HYAL2ENSG00000068001.9152.2171088.998500.774203.302602.15410K562DDX3X
HYAL2ENSG00000068001.9308.27930220.828300.481202.789202.13470K562DDX47
HYAL2ENSG00000068001.9118.9042051.992801.193304.942303.89410K562EIF3G
HYAL2ENSG00000068001.9149.5419083.726700.836703.968702.54040K562EIF4B
HYAL2ENSG00000068001.9403.64960269.329400.583604.439703.26100K562EIF4G2
HYAL2ENSG00000068001.9215.32900140.748700.613302.813501.95710K562FIP1L1
HYAL2ENSG00000068001.9186.4973096.691500.947605.154504.36470K562FXR1
HYAL2ENSG00000068001.95.5800032.95060-2.562004.344603.41500K562G3BP2
HYAL2ENSG00000068001.9186.44060105.410700.822603.606802.08440K562NONO
HYAL2ENSG00000068001.9233.14740159.799100.544902.521301.74290K562PPIG
HYAL2ENSG00000068001.9134.3761064.387101.061305.113604.23360K562PTBP1
HYAL2ENSG00000068001.9408.99010306.255300.417202.542301.62050K562PUM2
HYAL2ENSG00000068001.96.6079031.45090-2.250802.924901.46060K562RAVER1
HYAL2ENSG00000068001.9111.4345063.128500.819702.619801.92980K562SRSF1
HYAL2ENSG00000068001.9145.5551063.873601.188204.167603.29370K562TARDBP
HYAL2ENSG00000068001.913.2266033.03020-1.320402.007701.32370K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HYAL2 is not available on ENCORE database.





6 RBPs can affect the splicing of HYAL2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHYAL2ENSG00000068001.9chr3-5035879650359204503569995035796650360083503602080.362000.000320.02533includedHepG2RBM22
SEHYAL2ENSG00000068001.9chr3-5035879650359204503569995035796650360083503602080.274000.000550.06752includedHepG2HNRNPM
SEHYAL2ENSG00000068001.9chr3-5035879650359204503569995035796650360083503602080.543000.000320.02484includedHepG2NCBP2
SEHYAL2ENSG00000068001.9chr3-5035879650359204503569995035796650360083503602080.576000.000110.00879includedHepG2PTBP1
SEHYAL2ENSG00000068001.9chr3-5035879650359204503569995035796650360083503602080.488000.001050.04427includedHepG2MATR3
SEHYAL2ENSG00000068001.9chr3-5035879650359204503569995035796650360083503602080.290000.000130.00608includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HYAL2 is not avaliable on ENCORE database.