H6PD

General Information

Gene Name       : H6PD
Gene ID             : ENSG00000049239.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: H6PD)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878H6PDENSG00000049239.126.356.756.55ENCSR000AEF
HepG2H6PDENSG00000049239.125.934.985.46ENCSR985KAT
K562H6PDENSG00000049239.120.830.640.73ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for H6PD is not avaliable on ENCORE database.



Proteins bound to RNA
  • H6PD RNA is bound by 11 proteins.  







eCLIP assay for H6PD is not avaliable on ENCORE database.





11 proteins are bound to H6PD RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr193249639325070+3'-UTR5.1432714.79329HepG2AKAP1
chr193273009327351+3'-UTR4.003776.61524HepG2UPF1
chr193293989329518+3'-UTR,intron-Distal4.5997920.93905HepG2LIN28B
chr193257939325871+3'-UTR4.506207.88159HepG2UPF1
chr193280779328112+3'-UTR,intron-Proximal4.074887.84191HepG2UPF1
chr193275919327667+3'-UTR3.227964.45271HepG2YBX3
chr193249609325063+3'-UTR3.8202218.75456HepG2UPF1
chr193280129328077+3'-UTR3.9135713.75895HepG2UPF1
chr193293939329466+3'-UTR,intron-Distal4.395933.98564K562LIN28B
chr193303509330409+3'-UTR,intron-Distal4.142664.13513HepG2LIN28B
chr193271809327254+3'-UTR4.3911710.32152HepG2UPF1
chr193275919327674+3'-UTR3.859665.37198HepG2IGF2BP1
chr193262579326297+3'-UTR4.565005.67997HepG2UPF1
chr193257209325793+3'-UTR3.661915.83406HepG2UPF1
chr193271919327264+3'-UTR5.017416.37885HepG2IGF2BP1
chr193274919327543+3'-UTR4.343453.74540HepG2IGF2BP1
chr193270849327143+3'-UTR3.971665.91795HepG2UPF1
chr193249699325076+3'-UTR3.632426.68057HepG2PCBP2
chr193281439328222+3'-UTR,intron-Distal,intron-Proximal4.7697820.66476HepG2UPF1
chr193255109325607+3'-UTR3.364578.64325HepG2UPF1
chr193259069325996+3'-UTR5.5575011.24187HepG2UPF1
chr192950759295123+5'-UTR5.5640422.25688HepG2DDX3X
chr192949949295075+5'-UTR4.0314928.27563HepG2DDX3X
chr192948469294908+5'-UTR5.5676332.42793HepG2DDX3X
chr192949089294969+5'-UTR5.5102634.85211HepG2DDX3X
chr193050109305088+CDS5.0542514.58841HepG2DDX3X
chr193246039324639+CDS3.163523.68605HepG2AKAP1
chr193245039324553+CDS4.650296.23064HepG2UPF1
chr193241089324156+CDS3.324484.01829HepG2AKAP1
chr193054149305458+CDS3.791273.50564HepG2YBX3
chr193207169320802+intron-Distal3.870663.42785HepG2HNRNPM
chr193180339318089+intron-Distal4.659615.80264HepG2BCCIP
chr193181579318219+intron-Distal5.6612114.58669HepG2BCCIP
chr193180899318135+intron-Distal4.280924.40649HepG2BCCIP
chr193181589318224+intron-Distal4.157927.68916HepG2HNRNPM
chr193185309318579+intron-Distal4.254574.38558HepG2HNRNPM
chr193105659310677+intron-Distal5.9314112.14799HepG2DDX59
chr193205059320584+intron-Distal3.579154.87260HepG2HNRNPM
chr193178949317968+intron-Distal3.031133.53330HepG2BCCIP
chr193226399322702+intron-Distal4.052323.98590HepG2AKAP1
chr193104429310672+intron-Distal5.4872210.87872HepG2HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for H6PD is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for H6PD is not available on ENCORE database.

  • 133 RBPs can affect the levels of H6PD.  








The Knockdown/knockout RNA-Seq assay for H6PD is not available on ENCORE database.





133 RBPs can affect the gene expression of H6PD :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
H6PDENSG00000049239.81321.339301720.49960-0.380803.382202.20330HepG2AATF
H6PDENSG00000049239.8982.462601468.90910-0.580306.100504.69590HepG2ADAR
H6PDENSG00000049239.83235.657505090.91800-0.653907.201006.38750HepG2AKAP1
H6PDENSG00000049239.81694.103404212.23410-1.3141030.3587028.20190HepG2ASCC1
H6PDENSG00000049239.81535.596101177.896100.382502.395401.56120HepG2BCLAF1
H6PDENSG00000049239.8622.38700982.82220-0.659107.150606.24140HepG2BOP1
H6PDENSG00000049239.81262.997904001.93600-1.6638048.4851045.95290HepG2CIRBP
H6PDENSG00000049239.81728.825002591.10620-0.5838018.1726016.79380HepG2CKAP4
H6PDENSG00000049239.82150.48570902.259701.2529025.5285023.70490HepG2CPSF6
H6PDENSG00000049239.8514.31970837.28290-0.703007.456405.81460HepG2CSTF2
H6PDENSG00000049239.81288.143101762.13490-0.452002.797201.43340HepG2CSTF2T
H6PDENSG00000049239.83369.544102500.491800.4302011.9086010.54550HepG2DAZAP1
H6PDENSG00000049239.81946.821402397.02240-0.300105.044103.96390HepG2DDX19B
H6PDENSG00000049239.81734.837301247.091900.476102.767001.47620HepG2DDX27
H6PDENSG00000049239.8854.177604876.55730-2.5133095.2243092.02510HepG2DDX3X
H6PDENSG00000049239.81262.567501609.70870-0.350403.379201.88100HepG2DDX52
H6PDENSG00000049239.82089.577101479.113000.498408.757707.56140HepG2DNAJC21
H6PDENSG00000049239.81808.635001466.068500.302804.828604.00590HepG2DNAJC2
H6PDENSG00000049239.81216.082701600.79970-0.396603.264802.06260HepG2EFTUD2
H6PDENSG00000049239.83310.733404027.03690-0.282601.935701.42930HepG2EIF2S1
H6PDENSG00000049239.81140.120701558.85710-0.451303.692102.65600HepG2EIF3D
H6PDENSG00000049239.82722.678204450.17160-0.708808.275807.17510HepG2EIF4A3
H6PDENSG00000049239.82212.882504333.20550-0.9695011.6088010.24750HepG2EIF4B
H6PDENSG00000049239.84523.369202363.123300.9366019.2104017.22100HepG2EIF4G2
H6PDENSG00000049239.82740.296603816.23270-0.477807.061206.17520HepG2ETF1
H6PDENSG00000049239.81544.809102532.54330-0.7132012.7043010.96340HepG2EWSR1
H6PDENSG00000049239.82382.440301808.287400.397704.385902.99510HepG2FASTKD2
H6PDENSG00000049239.8849.465701109.42710-0.385202.738901.47710HepG2FKBP4
H6PDENSG00000049239.82010.404402864.02960-0.510607.183305.95440HepG2FUBP3
H6PDENSG00000049239.81625.914702222.91300-0.451202.731901.62190HepG2FUS
H6PDENSG00000049239.81981.096304490.57400-1.1806025.3937023.54700HepG2FXR1
H6PDENSG00000049239.82257.680404165.38310-0.8836013.3213011.92200HepG2G3BP1
H6PDENSG00000049239.83438.807304422.45760-0.362903.180102.22350HepG2G3BP2
H6PDENSG00000049239.8903.070701387.93310-0.620006.666305.27660HepG2GEMIN5
H6PDENSG00000049239.82440.460501792.343400.445203.924602.70910HepG2GNB2L1
H6PDENSG00000049239.81039.486301591.06300-0.614104.268902.89360HepG2GRSF1
H6PDENSG00000049239.82068.011301488.765800.474003.085601.48680HepG2HNRNPD
H6PDENSG00000049239.82100.108301390.654900.5946012.8711011.47600HepG2HNRNPF
H6PDENSG00000049239.8854.933004218.48790-2.3028095.9967092.31880HepG2HNRNPK
H6PDENSG00000049239.8873.641601743.28010-0.996708.544307.02520HepG2HNRNPM
H6PDENSG00000049239.81342.383101650.02540-0.297703.833203.13010HepG2HNRNPU
H6PDENSG00000049239.82516.896203274.04640-0.379402.572801.39210HepG2HSPD1
H6PDENSG00000049239.82277.426201369.387800.7338013.8951012.40320HepG2IGF2BP1
H6PDENSG00000049239.82227.335604233.92040-0.9267016.2489014.77940HepG2IGF2BP2
H6PDENSG00000049239.81265.269103973.75660-1.6511011.717909.81800HepG2IGF2BP3
H6PDENSG00000049239.82498.217804258.78850-0.769508.276406.46040HepG2KHSRP
H6PDENSG00000049239.82424.827204492.14410-0.8895014.4427012.99400HepG2MAGOH
H6PDENSG00000049239.82590.886104517.19870-0.8020010.718809.53730HepG2MATR3
H6PDENSG00000049239.81550.54690995.541500.639103.567702.45800HepG2MTPAP
H6PDENSG00000049239.8794.542304623.53300-2.5408092.4939089.19390HepG2NCBP2
H6PDENSG00000049239.81567.380101094.792400.517603.006701.49310HepG2NOLC1
H6PDENSG00000049239.81344.74580865.460700.635707.122205.95910HepG2NSUN2
H6PDENSG00000049239.82028.455804189.24450-1.0463051.2323049.24330HepG2PCBP1
H6PDENSG00000049239.81837.875701471.689800.320503.791702.94120HepG2PPIL4
H6PDENSG00000049239.81404.354002009.14110-0.5167010.223908.87310HepG2PRPF4
H6PDENSG00000049239.81366.372002211.99740-0.695005.253903.61620HepG2PRPF6
H6PDENSG00000049239.8733.299101028.05560-0.487403.870802.93500HepG2PRPF8
H6PDENSG00000049239.82276.078004262.75470-0.9052038.9973037.43730HepG2PTBP1
H6PDENSG00000049239.83111.010602512.552500.308106.837305.99070HepG2PUM1
H6PDENSG00000049239.81678.996902510.71680-0.5805010.151808.90930HepG2PUM2
H6PDENSG00000049239.81680.056502639.96990-0.6520020.2356018.84400HepG2PUS1
H6PDENSG00000049239.81223.259504616.57960-1.91610113.40630110.48950HepG2QKI
H6PDENSG00000049239.8928.245002030.39930-1.1292010.104208.82050HepG2RAVER1
H6PDENSG00000049239.81461.134701046.145700.481903.609101.61520HepG2RBM14
H6PDENSG00000049239.84149.931002976.862400.479208.205106.83310HepG2RBM15
H6PDENSG00000049239.81089.867703189.69560-1.5493074.6981072.74090HepG2RBM22
H6PDENSG00000049239.82253.565404189.87640-0.8947022.2351020.43680HepG2RBM25
H6PDENSG00000049239.81975.146404744.00200-1.2641072.6500070.81370HepG2NELFE
H6PDENSG00000049239.82668.651604418.45610-0.7274026.8305025.26120HepG2RECQL
H6PDENSG00000049239.82684.208101994.899800.428102.346001.47500HepG2RPS10
H6PDENSG00000049239.8924.566801516.93420-0.7143011.000409.87310HepG2RPS19
H6PDENSG00000049239.81424.445001952.79730-0.455104.313103.32240HepG2RPS2
H6PDENSG00000049239.82740.888901725.955800.667105.816604.65900HepG2RPS3A
H6PDENSG00000049239.8568.759301016.94020-0.838308.749007.45580HepG2RRP9
H6PDENSG00000049239.81925.606801522.325400.338902.531201.62950HepG2SERBP1
H6PDENSG00000049239.8955.577802969.45500-1.6358030.3870028.12260HepG2SF3A3
H6PDENSG00000049239.81786.78200966.009700.8872014.6553013.16750HepG2SF3B1
H6PDENSG00000049239.82709.072904438.00300-0.7121025.4441023.95990HepG2SF3B4
H6PDENSG00000049239.83282.639802269.474200.5324013.1428011.80790HepG2SLBP
H6PDENSG00000049239.81397.752101713.58340-0.293904.613403.81800HepG2SMN1
H6PDENSG00000049239.81349.702102071.49860-0.618004.847503.54690HepG2SMNDC1
H6PDENSG00000049239.81588.135801074.869100.563103.398602.52820HepG2SNRNP70
H6PDENSG00000049239.82442.890003602.69920-0.5605016.7675015.80760HepG2SRFBP1
H6PDENSG00000049239.81081.917504632.34490-2.09820192.49460190.21520HepG2SRSF1
H6PDENSG00000049239.82740.459202336.954000.229702.961702.31570HepG2SRSF5
H6PDENSG00000049239.81790.650301366.307900.390105.706104.76430HepG2SRSF7
H6PDENSG00000049239.83220.392303768.68560-0.226803.418402.81840HepG2SRSF9
H6PDENSG00000049239.82124.102303263.04670-0.619405.797304.02890HepG2SSRP1
H6PDENSG00000049239.81057.320901501.42200-0.505903.499202.24940HepG2STIP1
H6PDENSG00000049239.81450.283102657.75970-0.8739035.6237033.82420HepG2SUCLG1
H6PDENSG00000049239.83019.008401705.871000.8235014.8325012.79370HepG2SUPT6H
H6PDENSG00000049239.8844.398101326.86210-0.652006.285905.32730HepG2SUPV3L1
H6PDENSG00000049239.82549.807004163.81700-0.7075019.7680018.46430HepG2TAF15
H6PDENSG00000049239.81097.141101603.28730-0.547308.101007.32730HepG2TIAL1
H6PDENSG00000049239.82197.950701617.641700.442208.548307.64310HepG2TRIM56
H6PDENSG00000049239.8974.092602161.59840-1.150008.137307.06130HepG2U2AF1
H6PDENSG00000049239.8465.16650783.77890-0.752707.592006.33420HepG2UCHL5
H6PDENSG00000049239.82285.771302706.82380-0.243903.012601.92520HepG2UTP18
H6PDENSG00000049239.8971.457102542.49520-1.3880068.8411066.51210HepG2UTP3
H6PDENSG00000049239.81495.454702233.13100-0.578504.136502.84870HepG2XRCC6
H6PDENSG00000049239.81439.817501982.78150-0.4616010.029408.88350HepG2ZC3H8
H6PDENSG00000049239.829.3299091.85160-1.646905.670103.91130K562AARS
H6PDENSG00000049239.8217.6066097.470601.158606.880004.96400K562ABCF1
H6PDENSG00000049239.8163.26390358.59740-1.1352011.3709010.31440K562AGGF1
H6PDENSG00000049239.8163.09740373.13580-1.1940010.070108.72010K562AKAP8L
H6PDENSG00000049239.8255.62240391.50720-0.615004.669303.44750K562ATP5C1
H6PDENSG00000049239.8577.62450428.547100.430603.122901.85820K562CCDC124
H6PDENSG00000049239.8227.47590142.827200.671303.512902.25900K562CPEB4
H6PDENSG00000049239.8130.4065057.503401.181202.871902.07490K562CPSF6
H6PDENSG00000049239.8188.64950401.52760-1.0898012.5171010.35500K562DKC1
H6PDENSG00000049239.8129.0830074.423200.794402.796101.44400K562DNAJC21
H6PDENSG00000049239.850.46150108.38540-1.102903.971602.86180K562EFTUD2
H6PDENSG00000049239.8223.22630122.087200.870505.800504.01980K562EIF2S1
H6PDENSG00000049239.8343.1391095.910201.8389024.4010022.61880K562EIF2S2
H6PDENSG00000049239.8135.1252070.397600.940602.481301.53180K562EIF3A
H6PDENSG00000049239.8289.86650200.489100.531802.477601.58480K562EIF4G2
H6PDENSG00000049239.8103.4041058.532800.820902.322301.53670K562FMR1
H6PDENSG00000049239.8104.3503049.622501.072303.545502.50060K562FTO
H6PDENSG00000049239.869.70300120.77040-0.793002.858202.24490K562FXR1
H6PDENSG00000049239.8235.41780127.806300.881204.487003.52910K562GRSF1
H6PDENSG00000049239.8208.97800144.837800.528802.316801.34040K562HNRNPA1
H6PDENSG00000049239.8299.98440100.481101.5779014.5506013.26830K562HNRNPC
H6PDENSG00000049239.8181.8992089.739901.019205.240103.59910K562HNRNPF
H6PDENSG00000049239.819.27500130.77040-2.762207.027604.97940K562HNRNPK
H6PDENSG00000049239.819.7054057.63730-1.548403.449502.39990K562HNRNPM
H6PDENSG00000049239.8215.9753094.996901.184807.047105.78870K562HSPD1
H6PDENSG00000049239.8224.07890395.99410-0.821506.405905.03140K562KIF1C
H6PDENSG00000049239.8119.8430046.897001.353504.678703.42630K562KRR1
H6PDENSG00000049239.827.3165097.33320-1.833207.836205.34560K562LARP7
H6PDENSG00000049239.8231.16270379.06070-0.713502.767301.69100K562MAK16
H6PDENSG00000049239.8211.79220443.61290-1.0667010.771308.78030K562MBNL1
H6PDENSG00000049239.8143.3458053.584501.419506.904705.48890K562METAP2
H6PDENSG00000049239.8206.81080126.260700.711803.769702.83740K562MTPAP
H6PDENSG00000049239.8115.64240310.94020-1.427008.831206.90330K562NAA15
H6PDENSG00000049239.857.31420122.44920-1.095202.537501.60180K562PCBP2
H6PDENSG00000049239.8382.72280141.681001.4336013.2031011.40110K562PCBP3
H6PDENSG00000049239.8262.77690108.665101.2738010.414208.90500K562POLR2G
H6PDENSG00000049239.831.29930105.47230-1.752706.908205.72130K562PRPF8
H6PDENSG00000049239.8473.79040227.956601.0554011.032909.10480K562PUM2
H6PDENSG00000049239.863.24650370.05600-2.5487032.2355030.35620K562PUS1
H6PDENSG00000049239.8125.30680360.55750-1.5248017.5258016.01050K562RBM15
H6PDENSG00000049239.841.4657076.85810-0.890302.165101.40890K562SF3B4
H6PDENSG00000049239.858.77830131.15080-1.157902.467001.79300K562SRSF1
H6PDENSG00000049239.8289.47620141.564501.031903.949902.11940K562SUPT6H
H6PDENSG00000049239.840.69120109.00640-1.421606.139104.90760K562SYNCRIP
H6PDENSG00000049239.8255.12630132.687300.943102.878902.15850K562TARDBP
H6PDENSG00000049239.8271.47390128.003901.084508.427906.88690K562TIA1
H6PDENSG00000049239.8167.9155092.074200.866803.783502.64450K562TRIM56
H6PDENSG00000049239.8168.1603081.951901.036904.991603.00750K562TRIP6
H6PDENSG00000049239.8181.69720108.057600.749602.988801.92330K562UCHL5
H6PDENSG00000049239.8210.72420148.759000.502302.175301.53300K562UPF1
H6PDENSG00000049239.883.43270153.73870-0.881804.265302.16590K562UPF2
H6PDENSG00000049239.8257.24830101.405001.342909.674907.57760K562UTP3
H6PDENSG00000049239.8213.34780127.289700.745003.938302.88770K562WDR3
H6PDENSG00000049239.856.40690133.62800-1.244304.557402.39560K562XRCC6
H6PDENSG00000049239.8177.37240110.066500.688302.631101.46060K562XRN2
H6PDENSG00000049239.8334.92250143.641501.221305.060003.83750K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for H6PD is not available on ENCORE database.





2 RBPs can affect the splicing of H6PD :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEH6PDENSG00000049239.8chr1+9306842930694293049839305620930702493071420.520000.000010.00019includedHepG2U2AF2
SEH6PDENSG00000049239.8chr1+929987393000779294833929512593049839305620-0.521000.000870.05888excludedHepG2IGF2BP3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for H6PD is not avaliable on ENCORE database.