CRKL

General Information

Gene Name       : CRKL
Gene ID             : ENSG00000099942.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CRKL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CRKLENSG00000099942.1223.6625.0124.34ENCSR000AEF
HepG2CRKLENSG00000099942.1229.5531.4730.51ENCSR985KAT
K562CRKLENSG00000099942.12104.10105.07104.58ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
CRKL38710S1Submitted, ENCORE2BGHcLV43-11, Submitted, ENCORE2BGKcLV42-19, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
CRKLK562CRISPRCRKL-BGKcLV42-19,CRKL-BGKcLV42-20NT-BGKcLV42-1,NT-BGKcLV42-287.2,84.8SequencedENCORE2
CRKLHepG2CRISPRCRKL-BGHcLV43-11,CRKL-BGHcLV43-12NT-BGHcLV43-1,NT-BGHcLV43-287.5,89.4SequencedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
CRKLProduct_ID: 38710S
Lot_ID: 1
Source: Cell Signaling Technology
Target Name: CRKL-human		 CRKL-HEPG2-CRISPR-38710S.png<br>Caption: Western blot following CRISPR against CRKL in HepG2 whole cell lysate using CRKL specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against CRKL. CRKL protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
 CST_38710S_1_CRKL.png<br>Caption: IP-WB analysis of 38710S whole cell lysate using the CRKL specific antibody, 38710S. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the CRKL-specific antibody, 38710S. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
 CRKL-K562-CRISPR-38710S.png<br>Caption: Western blot following CRISPR against CRKL in K562 whole cell lysate using CRKL specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against CRKL. CRKL protein appears as the green arrow, Tubulin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for CRKL is not avaliable on ENCORE database.



Proteins bound to RNA
  • CRKL RNA is bound by 34 proteins.  







eCLIP assay for CRKL is not avaliable on ENCORE database.





34 proteins are bound to CRKL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr222130777221307788+3'-UTR5.268488.64032K562IGF2BP1
chr222130452421304583+3'-UTR,intron-Distal3.6761123.70093K562RBM15
chr222130537321305395+3'-UTR,intron-Distal3.6848641.76812K562UPF1
chr222130596221306011+3'-UTR,intron-Distal4.8132759.22614K562UPF1
chr222130656921306598+3'-UTR,intron-Distal5.5191311.55119K562IGF2BP2
chr222130686321306912+3'-UTR,intron-Distal3.4311372.05828K562UPF1
chr222130580921305880+3'-UTR,intron-Distal3.2695458.78693K562UPF1
chr222130503921305084+3'-UTR,intron-Distal3.360664.41670HepG2AKAP1
chr222130520221305222+3'-UTR,intron-Distal3.373776.74715K562IGF2BP1
chr222130725821307282+3'-UTR,intron-Distal4.3824321.42618K562XRCC6
chr222130701721307038+3'-UTR,intron-Distal4.024117.95579K562IGF2BP1
chr222130474621304762+3'-UTR,intron-Distal3.179698.91116K562HNRNPC
chr222130799321308027+3'-UTR3.637148.51424K562PABPC4
chr222130684221306903+3'-UTR,intron-Distal3.7337424.69214K562IGF2BP1
chr222130614921306193+3'-UTR,intron-Distal3.4995044.61714K562UPF1
chr222130421821304240+3'-UTR,intron-Proximal4.8031133.46449K562IGF2BP1
chr222130433321304351+3'-UTR,intron-Distal3.4261712.00912K562RBM15
chr222130551621305556+3'-UTR,intron-Distal4.0999752.14519K562UPF1
chr222130722321307283+3'-UTR,intron-Distal4.014528.12409K562PCBP1
chr222130526121305293+3'-UTR,intron-Distal3.458669.44087K562AKAP1
chr222130576721305826+3'-UTR,intron-Distal3.9240611.56828K562IGF2BP2
chr222130758021307610+3'-UTR3.8315911.05257K562IGF2BP2
chr222130679421306806+3'-UTR,intron-Distal4.1433711.18362K562IGF2BP2
chr222130530121305329+3'-UTR,intron-Distal5.1859387.79923K562UPF1
chr222130427821304302+3'-UTR,intron-Proximal3.4567468.55945K562PUM2
chr222130532921305350+3'-UTR,intron-Distal4.7130462.02659K562UPF1
chr222130421721304329+3'-UTR,intron-Distal,intron-Proximal4.724016.13324HepG2IGF2BP1
chr222130679121306807+3'-UTR,intron-Distal4.1741742.05143K562UPF1
chr222130681221306829+3'-UTR,intron-Distal5.8084531.10802K562IGF2BP1
chr222130681221306844+3'-UTR,intron-Distal3.423193.38325HepG2IGF2BP1
chr222130567821305736+3'-UTR,intron-Distal3.2728454.76894K562UPF1
chr222130432321304353+3'-UTR,intron-Distal3.1458528.74081K562UPF1
chr222130602521306082+3'-UTR,intron-Distal4.7132333.55821K562IGF2BP1
chr222130779421307875+3'-UTR3.7851010.68712HepG2FUBP3
chr222130426021304302+3'-UTR,intron-Proximal4.6512531.00464K562IGF2BP1
chr222130425521304273+3'-UTR,intron-Proximal4.0866917.12569K562RBM15
chr222130424021304260+3'-UTR,intron-Proximal5.0856842.63470K562IGF2BP1
chr222130545421305513+3'-UTR,intron-Distal3.6925460.51684K562UPF1
chr222130643421306524+3'-UTR,intron-Distal3.83779400.00000K562UPF1
chr222130782221307844+3'-UTR3.4956824.86592K562UPF1
chr222130676321306785+3'-UTR,intron-Distal6.1906420.44450K562IGF2BP1
chr222130517321305202+3'-UTR,intron-Distal3.030804.98864K562IGF2BP1
chr222130591421305962+3'-UTR,intron-Distal4.3898962.53916K562UPF1
chr222130665321306701+3'-UTR,intron-Distal3.5415745.75061K562UPF1
chr222130683621306863+3'-UTR,intron-Distal3.1366049.28333K562UPF1
chr222130746621307518+3'-UTR,intron-Proximal3.930363.45716HepG2AKAP1
chr222130436821304402+3'-UTR,intron-Distal4.9833622.32195K562IGF2BP1
chr222130716621307187+3'-UTR,intron-Distal4.314766.04687K562ZC3H11A
chr222130525421305301+3'-UTR,intron-Distal5.3258782.22233K562UPF1
chr222130682921306839+3'-UTR,intron-Distal4.2648814.03436K562IGF2BP1
chr222130416221304222+3'-UTR,intron-Proximal4.036113.45716HepG2AKAP1
chr222130684421306944+3'-UTR,intron-Distal3.600744.34898HepG2IGF2BP1
chr222130427221304319+3'-UTR,intron-Distal,intron-Proximal4.2702427.73128K562IGF2BP2
chr222130420021304218+3'-UTR,intron-Proximal3.9821924.86761K562IGF2BP1
chr222130678921306812+3'-UTR,intron-Distal5.9994439.99644K562IGF2BP1
chr222130417421304200+3'-UTR3.1373614.08555K562IGF2BP1
chr222130472321304746+3'-UTR,intron-Distal3.7974015.57626K562HNRNPC
chr222130793621307999+3'-UTR4.1838226.72895K562TIA1
chr222130683321306909+3'-UTR,intron-Distal3.086723.47572HepG2IGF2BP3
chr222130561421305659+3'-UTR,intron-Distal3.9125755.80022K562UPF1
chr222130438521304398+3'-UTR,intron-Distal3.445815.65018K562IGF2BP2
chr222130421521304304+3'-UTR,intron-Proximal4.168036.29084HepG2RBM15
chr222130476321304787+3'-UTR,intron-Distal3.7822826.38401K562UPF1
chr222130635121306378+3'-UTR,intron-Distal3.8375033.41338K562UPF1
chr222130509021305101+3'-UTR,intron-Distal3.4061922.69146K562UPF1
chr222130439821304415+3'-UTR,intron-Distal3.116055.30255K562IGF2BP2
chr222130704821307058+3'-UTR,intron-Distal4.3195856.93494K562UPF1
chr222130525421305297+3'-UTR,intron-Distal4.5384920.69312K562IGF2BP1
chr222130570321305741+3'-UTR,intron-Distal3.629869.47165K562IGF2BP1
chr222130781721307849+3'-UTR3.358017.58767K562IGF2BP1
chr222130665521306710+3'-UTR,intron-Distal3.9144811.49435K562IGF2BP1
chr222130423921304272+3'-UTR,intron-Proximal3.2303322.33873K562IGF2BP2
chr222130427321304314+3'-UTR,intron-Proximal3.5837220.62353K562RBM15
chr222130415521304205+3'-UTR4.7491856.88074K562RBM15
chr222130442721304476+3'-UTR,intron-Distal4.9718034.10602K562RBM15
chr222130592521305963+3'-UTR,intron-Distal3.502959.95464K562IGF2BP1
chr222130794121308024+3'-UTR3.9211773.52516K562PUM2
chr222130430221304389+3'-UTR,intron-Distal,intron-Proximal4.03844400.00000K562PUM2
chr222130704321307051+3'-UTR,intron-Distal3.976906.95607K562IGF2BP2
chr222130516221305191+3'-UTR,intron-Distal4.2234446.86729K562UPF1
chr222130514421305162+3'-UTR,intron-Distal4.4231639.06853K562UPF1
chr222130447621304501+3'-UTR,intron-Distal4.4522523.22068K562RBM15
chr222130793421307990+3'-UTR3.6467117.28551K562ZC3H11A
chr222130424221304255+3'-UTR,intron-Proximal3.9666920.93968K562RBM15
chr222130463521304677+3'-UTR,intron-Distal3.7707227.50569K562UPF1
chr222130565921305678+3'-UTR,intron-Distal3.3962035.74350K562UPF1
chr222130626721306283+3'-UTR,intron-Distal3.3752722.16309K562UPF1
chr222130555621305578+3'-UTR,intron-Distal3.8825832.99229K562UPF1
chr222130490821304988+3'-UTR,intron-Distal4.140508.44905HepG2UPF1
chr222130450121304524+3'-UTR,intron-Distal3.9797521.29316K562RBM15
chr222130545021305545+3'-UTR,intron-Distal5.101386.52213HepG2UPF1
chr222130471121304723+3'-UTR,intron-Distal3.6753113.20199K562HNRNPC
chr222130412521304155+3'-UTR,CDS4.4139725.48295K562RBM15
chr222130680721306835+3'-UTR,intron-Distal3.5607055.26074K562UPF1
chr222130796321307983+3'-UTR4.7559415.04597K562IGF2BP1
chr222130522221305247+3'-UTR,intron-Distal4.1190917.78005K562IGF2BP1
chr222130703321307044+3'-UTR,intron-Distal4.7983971.21793K562UPF1
chr222130535021305373+3'-UTR,intron-Distal4.0187453.02213K562UPF1
chr222130705921307068+3'-UTR,intron-Distal3.9347153.10078K562UPF1
chr222130652421306573+3'-UTR,intron-Distal3.7661749.95511K562UPF1
chr222130602521306130+3'-UTR,intron-Distal3.95277400.00000K562UPF1
chr222130430321304368+3'-UTR,intron-Distal,intron-Proximal4.1682822.18102K562IGF2BP1
chr222130699721307033+3'-UTR,intron-Distal4.9549578.54519K562UPF1
chr222130781921307866+3'-UTR3.969477.62465K562TIA1
chr222130468921304802+3'-UTR,intron-Distal4.6582125.02388HepG2UPF1
chr222130420521304223+3'-UTR,intron-Proximal3.9392818.89272K562RBM15
chr222130706821307129+3'-UTR,intron-Distal4.41925400.00000K562UPF1
chr222130537621305411+3'-UTR,intron-Distal3.739737.25106K562IGF2BP1
chr222130580521305857+3'-UTR,intron-Distal3.2249111.88028K562IGF2BP1
chr222130740021307427+3'-UTR,intron-Proximal3.5878624.70402K562UPF1
chr222130579121305829+3'-UTR,intron-Distal3.0073123.71863K562YBX3
chr222130468421304711+3'-UTR,intron-Distal3.8020314.80410K562HNRNPC
chr222130728221307311+3'-UTR,intron-Distal3.9539119.59017K562XRCC6
chr222130446821304530+3'-UTR,intron-Distal3.160073.52299HepG2AKAP1
chr222130574121305787+3'-UTR,intron-Distal3.7560913.36708K562IGF2BP1
chr222127212721272259+5'-UTR,CDS4.3487716.08308K562SERBP1
chr222127200821272062+5'-UTR4.254609.76063HepG2DDX3X
chr222127195921272206+5'-UTR3.0746711.57762HepG2RPS3
chr222127182821271943+5'-UTR4.6737222.47508HepG2DDX3X
chr222127207221272099+5'-UTR3.028953.99619K562FXR2
chr222127194321272008+5'-UTR3.8571812.20639HepG2DDX3X
chr222127207421272145+5'-UTR3.267735.32728HepG2DDX3X
chr222127196521271970+5'-UTR3.466898.56617K562RBM15
chr222127173021271807+5'-UTR4.3507640.17737K562DDX3X
chr222127201521272099+5'-UTR3.4657819.54502K562RPS3
chr222127181321271871+5'-UTR4.1402318.10501K562DDX3X
chr222127193521272015+5'-UTR3.1120620.34419K562RPS3
chr222128816021288205+CDS4.609734.34093HepG2RBM15
chr222128840821288498+CDS3.9641035.30397K562IGF2BP1
chr222130403521304119+CDS5.0411427.67052K562RBM15
chr222127251621272576+CDS,intron-Proximal4.249335.93840HepG2PRPF8
chr222128853121288585+CDS,intron-Proximal3.944759.04524K562AQR
chr222128841121288442+CDS3.9041421.15186K562RBM15
chr222128840321288493+CDS3.748497.20140HepG2RBM15
chr222128816021288367+CDS3.2732215.60248K562ZNF800
chr222127233721272385+CDS3.361416.04702K562ZNF800
chr222130396121304031+CDS,intron-Proximal3.9421612.83194K562BUD13
chr222128806621288115+CDS,intron-Proximal3.2334314.23168K562IGF2BP2
chr222128834521288395+CDS3.8623519.27737K562IGF2BP2
chr222128840621288474+CDS5.1909876.00834K562IGF2BP2
chr222128829021288332+CDS5.0045514.74470K562LIN28B
chr222128844221288457+CDS3.5643917.28266K562RBM15
chr222128846221288563+CDS,intron-Proximal4.888645.35117HepG2PRPF8
chr222127244421272534+CDS,intron-Proximal3.0541117.04663K562METAP2
chr222128823421288289+CDS3.5821418.64705K562RBM15
chr222128828921288322+CDS4.3459719.40189K562RBM15
chr222128846921288491+CDS4.9581122.22363K562RBM15
chr222128839521288406+CDS4.0009816.13609K562IGF2BP2
chr222130397121304000+CDS,intron-Proximal4.753896.48405K562AQR
chr222128824121288281+CDS3.9067510.67331K562IGF2BP2
chr222128838921288471+CDS4.935257.20566HepG2IGF2BP1
chr222127233521272444+CDS3.2929418.55625K562METAP2
chr222127232421272413+CDS3.238967.63489K562PCBP1
chr222128826921288290+CDS4.5322416.05645K562LIN28B
chr222130394721304045+CDS,intron-Proximal3.659954.40430HepG2AQR
chr222128820521288323+CDS3.3010314.53420K562NOLC1
chr222127245421272458+CDS3.3274519.59054K562YBX3
chr222127248021272485+CDS3.2470727.19200K562YBX3
chr222128849121288511+CDS6.2808621.76051K562RBM15
chr222128815521288205+CDS3.2568622.85072K562RBM15
chr222130395321304019+CDS,intron-Proximal4.1269420.22844K562SF3B4
chr222129494321295024+intron-Distal3.639464.72029K562MATR3
chr222130375421303810+intron-Distal4.368384.28709K562ILF3
chr222129400821294061+intron-Distal4.022753.53404K562HNRNPM
chr222129525221295315+intron-Distal3.475964.26619K562MATR3
chr222127493021274981+intron-Distal4.559377.80454K562PTBP1
chr222127500221275077+intron-Distal3.565043.30286HepG2PTBP1
chr222129499921295041+intron-Distal3.352003.59523HepG2SUGP2
chr222128318121283248+intron-Distal3.110967.10959K562ILF3
chr222127515521275212+intron-Distal3.513383.69083K562PTBP1
chr222127851021278610+intron-Distal3.9194311.56427K562ILF3
chr222127498121275030+intron-Distal3.789865.37650K562PTBP1
chr222128682621286877+intron-Distal3.397833.62066K562ILF3
chr222129163021291699+intron-Distal3.567557.22631K562TARDBP
chr222129171121291816+intron-Distal4.0637012.81753K562TARDBP
chr222127272721272778+intron-Distal4.366177.44508K562PRPF8
chr222129974321299828+intron-Distal4.246583.58835K562HNRNPK
chr222127839221278427+intron-Distal3.248053.62066K562ILF3
chr222127808021278139+intron-Distal3.177375.60121K562ILF3
chr222127825721278303+intron-Distal3.355114.52160K562ILF3
chr222127259121272680+intron-Distal,intron-Proximal4.3253416.17397K562PRPF8
chr222129205321292092+intron-Distal4.254993.34609K562TARDBP
chr222128426721284341+intron-Distal3.105353.94380K562ILF3
chr222128405821284121+intron-Distal3.337685.03045K562ILF3
chr222127260721272625+intron-Proximal5.3191810.38360K562RBM15
chr222127256421272575+intron-Proximal3.636868.17562K562AQR
chr222128800821288048+intron-Proximal4.699633.62536K562AQR
chr222127254121272564+intron-Proximal3.234408.11224K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CRKL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CRKL is not available on ENCORE database.

  • 142 RBPs can affect the levels of CRKL.  








The Knockdown/knockout RNA-Seq assay for CRKL is not available on ENCORE database.





142 RBPs can affect the gene expression of CRKL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CRKLENSG00000099942.82915.255403597.25520-0.303305.820005.00160HepG2ACO1
CRKLENSG00000099942.82850.598404851.22090-0.767109.559908.63570HepG2AKAP1
CRKLENSG00000099942.82298.920703155.61790-0.457004.034402.78230HepG2AKAP8
CRKLENSG00000099942.82527.071303614.03350-0.5161012.9593011.46210HepG2AKAP8L
CRKLENSG00000099942.82407.168904013.88590-0.7377010.539009.07790HepG2ASCC1
CRKLENSG00000099942.84637.640404033.021800.201402.794702.10590HepG2AUH
CRKLENSG00000099942.81683.506702626.28450-0.641606.182204.75760HepG2BCCIP
CRKLENSG00000099942.82602.825102110.508400.302402.487501.91680HepG2BOP1
CRKLENSG00000099942.82992.953303975.23370-0.409502.752501.77960HepG2CCAR1
CRKLENSG00000099942.81502.020703596.32600-1.2596085.1754082.77180HepG2CKAP4
CRKLENSG00000099942.83187.439103857.93550-0.275403.753003.02680HepG2CELF1
CRKLENSG00000099942.83446.945004147.93770-0.267105.173104.20600HepG2DAZAP1
CRKLENSG00000099942.82150.614503326.87790-0.6294021.8351020.02660HepG2DDX19B
CRKLENSG00000099942.81885.953302869.63130-0.605609.026007.87490HepG2DDX21
CRKLENSG00000099942.82149.769102808.38260-0.385604.648103.45380HepG2DDX24
CRKLENSG00000099942.81805.203602416.12010-0.420502.781901.48820HepG2DDX27
CRKLENSG00000099942.82940.987504646.90480-0.660008.419207.37790HepG2DDX3X
CRKLENSG00000099942.82050.758703441.56030-0.7469025.1360023.60200HepG2DKC1
CRKLENSG00000099942.81839.838602641.81950-0.5220015.3883013.97530HepG2DNAJC2
CRKLENSG00000099942.81430.403002672.62580-0.9018014.8833013.01350HepG2EEF2
CRKLENSG00000099942.81098.745802228.13940-1.0200018.3163015.58830HepG2EFTUD2
CRKLENSG00000099942.81623.724402169.64060-0.418103.357402.36640HepG2EIF3D
CRKLENSG00000099942.82205.006202710.05520-0.297503.020001.89770HepG2EIF3G
CRKLENSG00000099942.82180.529804240.54070-0.9596014.2648012.83890HepG2EIF4A3
CRKLENSG00000099942.82722.787104129.18830-0.600804.925204.02430HepG2EIF4B
CRKLENSG00000099942.85267.147303920.255600.426004.874203.81180HepG2EIF4G2
CRKLENSG00000099942.82345.390702870.26070-0.291402.309901.30680HepG2ESF1
CRKLENSG00000099942.84117.370104630.29820-0.169401.998301.46940HepG2ETF1
CRKLENSG00000099942.82458.005603515.03020-0.516006.774805.47090HepG2EWSR1
CRKLENSG00000099942.81601.294701938.99310-0.276102.529901.41340HepG2FAM120A
CRKLENSG00000099942.82160.399402734.77610-0.340103.444102.18980HepG2FASTKD2
CRKLENSG00000099942.82224.998103346.34410-0.588805.193104.16680HepG2FIP1L1
CRKLENSG00000099942.82195.573703377.22770-0.621204.925003.46080HepG2FUS
CRKLENSG00000099942.83351.917704279.20450-0.352402.963702.24660HepG2FXR1
CRKLENSG00000099942.81820.914903969.23370-1.1242020.5120018.78230HepG2G3BP1
CRKLENSG00000099942.82977.944204214.31550-0.501005.495804.22780HepG2G3BP2
CRKLENSG00000099942.81372.312101931.80380-0.493305.143703.91810HepG2GEMIN5
CRKLENSG00000099942.81481.063602196.14960-0.568305.574304.68720HepG2GPKOW
CRKLENSG00000099942.81542.923902681.70070-0.797507.199605.41360HepG2GRSF1
CRKLENSG00000099942.82153.294803236.39680-0.587803.479201.90610HepG2HLTF
CRKLENSG00000099942.81603.431302691.00100-0.7470013.3543012.10540HepG2HNRNPA1
CRKLENSG00000099942.81678.392102393.22600-0.511903.889402.21300HepG2HNRNPAB
CRKLENSG00000099942.81499.149802993.20460-0.9975022.1490020.39250HepG2HNRNPC
CRKLENSG00000099942.81837.634802509.12820-0.449302.876601.32850HepG2HNRNPD
CRKLENSG00000099942.82737.892603778.36580-0.4647014.4836013.05140HepG2HNRNPL
CRKLENSG00000099942.81692.857202308.20730-0.447304.875403.65510HepG2HNRNPM
CRKLENSG00000099942.81733.857002973.41800-0.7781027.0993025.36200HepG2HNRNPU
CRKLENSG00000099942.82003.794503435.85940-0.777908.662206.55770HepG2HSPD1
CRKLENSG00000099942.83280.002004034.51270-0.298702.234001.61970HepG2IGF2BP2
CRKLENSG00000099942.81511.740903786.72610-1.324708.222306.60050HepG2IGF2BP3
CRKLENSG00000099942.81983.236603037.25430-0.6149022.6633020.80560HepG2ILF2
CRKLENSG00000099942.82035.849502824.13900-0.472202.928001.55980HepG2ILF3
CRKLENSG00000099942.81978.603302761.64660-0.481003.613602.22030HepG2KHDRBS1
CRKLENSG00000099942.81896.676304058.26720-1.0974015.7327013.22720HepG2KHSRP
CRKLENSG00000099942.82819.961503288.25060-0.221603.698602.52000HepG2KIF1C
CRKLENSG00000099942.81865.252103433.20840-0.880209.633407.39090HepG2KRR1
CRKLENSG00000099942.82920.934304197.83370-0.523204.292003.25260HepG2LARP4
CRKLENSG00000099942.81813.481002569.19970-0.502605.748804.13020HepG2LARP7
CRKLENSG00000099942.81999.437102698.24300-0.432404.164702.67460HepG2LIN28B
CRKLENSG00000099942.82717.125804280.70150-0.655808.312107.18660HepG2MAGOH
CRKLENSG00000099942.81573.563402176.09660-0.467704.206802.25990HepG2MARK2
CRKLENSG00000099942.82188.361004304.55000-0.9760015.3156013.92380HepG2MATR3
CRKLENSG00000099942.81367.099402270.77010-0.732105.902604.41290HepG2METAP2
CRKLENSG00000099942.81658.080602707.31720-0.707309.650508.22600HepG2MSI2
CRKLENSG00000099942.82901.168504405.85680-0.602806.910405.93000HepG2NCBP2
CRKLENSG00000099942.82878.955304113.10200-0.514709.660308.26220HepG2NOL12
CRKLENSG00000099942.81686.251602370.91540-0.491602.341101.34330HepG2NONO
CRKLENSG00000099942.82531.311103256.59230-0.363503.687701.82080HepG2NUP35
CRKLENSG00000099942.8928.481501622.05410-0.804905.792303.56010HepG2PA2G4
CRKLENSG00000099942.81696.238802943.22040-0.7951026.2653024.17400HepG2PARN
CRKLENSG00000099942.82738.077103965.22860-0.5342014.3520013.14620HepG2PCBP1
CRKLENSG00000099942.82340.689103197.07960-0.449802.671201.65010HepG2PCBP2
CRKLENSG00000099942.81148.186701794.22720-0.6440011.071408.82570HepG2PKM
CRKLENSG00000099942.82353.770303337.06360-0.503604.272302.03140HepG2PPIG
CRKLENSG00000099942.81857.060102652.05770-0.514109.807308.46400HepG2PPIL4
CRKLENSG00000099942.82465.350803360.96070-0.447102.585501.40220HepG2PRPF6
CRKLENSG00000099942.8567.289001992.10580-1.8121045.4532042.83430HepG2PRPF8
CRKLENSG00000099942.82739.468504034.92150-0.5586015.6008014.50450HepG2PTBP1
CRKLENSG00000099942.82092.144804168.13690-0.9944062.2280060.19940HepG2PUM1
CRKLENSG00000099942.82436.124304165.03390-0.7737019.3967017.71720HepG2PUM2
CRKLENSG00000099942.82511.764203664.01620-0.5447016.8776015.58470HepG2PUS1
CRKLENSG00000099942.83695.267504369.59330-0.241802.632902.02070HepG2QKI
CRKLENSG00000099942.81399.449703085.37190-1.1406010.703309.38070HepG2RAVER1
CRKLENSG00000099942.82263.207103870.10390-0.7740022.9016021.70240HepG2RBM22
CRKLENSG00000099942.82074.271103097.96240-0.578706.253904.75450HepG2RBM27
CRKLENSG00000099942.82946.648304490.35300-0.6078018.4788017.32070HepG2NELFE
CRKLENSG00000099942.82746.692904182.38430-0.6066018.5440017.18300HepG2RECQL
CRKLENSG00000099942.81027.455802111.10170-1.0389024.1376022.61170HepG2RPS19
CRKLENSG00000099942.82093.717402857.27470-0.448604.188903.21270HepG2RPS2
CRKLENSG00000099942.81840.979802910.15640-0.660605.743604.58940HepG2RPS3A
CRKLENSG00000099942.81888.447702916.51480-0.627007.543905.78680HepG2RPS5
CRKLENSG00000099942.8985.546401970.62330-0.9997013.9181012.38870HepG2RRP9
CRKLENSG00000099942.82148.640102647.98170-0.301505.306904.46710HepG2SAFB2
CRKLENSG00000099942.81597.782702118.90520-0.407203.332402.29690HepG2SERBP1
CRKLENSG00000099942.82721.286204200.59950-0.6263019.4869018.14630HepG2SF3B4
CRKLENSG00000099942.81763.686203088.03040-0.8081038.7193036.81230HepG2SMN1
CRKLENSG00000099942.81591.729302308.13950-0.536103.349002.48420HepG2SNRNP70
CRKLENSG00000099942.82602.383204384.62850-0.7526030.2997029.10540HepG2SRSF1
CRKLENSG00000099942.82968.052203876.85690-0.385407.621406.65080HepG2SRSF5
CRKLENSG00000099942.82853.532003567.22540-0.322106.030205.27180HepG2SRSF9
CRKLENSG00000099942.82615.959403423.39170-0.388102.861501.55880HepG2SSRP1
CRKLENSG00000099942.82973.077404408.95800-0.5685020.1473018.71690HepG2SUCLG1
CRKLENSG00000099942.82432.051003465.80000-0.511003.918202.32730HepG2SUGP2
CRKLENSG00000099942.82819.304902258.758600.319702.814101.86640HepG2SUPT6H
CRKLENSG00000099942.8985.813502570.54400-1.3827027.0729025.35510HepG2SUPV3L1
CRKLENSG00000099942.82893.903603941.38600-0.445708.218307.33580HepG2TAF15
CRKLENSG00000099942.81621.903502043.22250-0.333202.768002.04370HepG2TARDBP
CRKLENSG00000099942.8862.770001722.97840-0.9979013.4211011.56370HepG2TFIP11
CRKLENSG00000099942.82504.486503621.26690-0.532008.606907.14320HepG2TIA1
CRKLENSG00000099942.81475.873302889.36800-0.9692027.7746026.49500HepG2TIAL1
CRKLENSG00000099942.81844.330902915.05000-0.6604019.9340018.59530HepG2TRIM56
CRKLENSG00000099942.82839.410803836.07630-0.434005.868104.53220HepG2TUFM
CRKLENSG00000099942.8762.027001518.53630-0.9948014.8911013.16360HepG2UCHL5
CRKLENSG00000099942.82438.485203376.63550-0.4696012.0828010.81110HepG2UPF1
CRKLENSG00000099942.82717.029803470.67090-0.353206.073404.57740HepG2UTP18
CRKLENSG00000099942.82823.442703260.00110-0.207402.924602.31210HepG2UTP3
CRKLENSG00000099942.82275.354203392.98080-0.576504.325303.01310HepG2XRCC6
CRKLENSG00000099942.81594.825602530.41700-0.666007.912306.69660HepG2XRN2
CRKLENSG00000099942.81217.163902356.16780-0.9529040.0020038.05840HepG2ZC3H8
CRKLENSG00000099942.82585.501003713.64550-0.5224018.7289017.61970HepG2ZNF622
CRKLENSG00000099942.821757.4878013410.237500.6981022.4072020.90050K562AGGF1
CRKLENSG00000099942.818998.0585014736.561100.366402.953301.92750K562AKAP8
CRKLENSG00000099942.821885.5151013954.141300.6492012.8629011.30800K562AKAP8L
CRKLENSG00000099942.819070.5280022656.08950-0.248602.615401.40930K562APOBEC3C
CRKLENSG00000099942.857519.0626020769.524801.4695058.1902055.84460K562AQR
CRKLENSG00000099942.812615.7913018841.40700-0.5787021.5629019.90840K562DDX47
CRKLENSG00000099942.818292.5487015014.518400.284804.150303.04700K562DKC1
CRKLENSG00000099942.85567.662406996.36340-0.329503.180001.73720K562DNAJC21
CRKLENSG00000099942.812136.4836014739.93140-0.280403.920703.08730K562EIF2S2
CRKLENSG00000099942.817006.1331011600.733200.551705.777704.20690K562EIF3D
CRKLENSG00000099942.810964.054208148.954400.428008.017705.60390K562FUS
CRKLENSG00000099942.814009.8610019640.72390-0.487406.448805.28720K562GRSF1
CRKLENSG00000099942.818103.9279011674.817200.632802.906401.65190K562HNRNPA2B1
CRKLENSG00000099942.87573.928509659.08250-0.350804.589303.83880K562HNRNPC
CRKLENSG00000099942.814492.0958016480.60140-0.185502.094901.31920K562HNRNPU
CRKLENSG00000099942.811047.3991016958.19060-0.6183010.085108.59350K562HSPD1
CRKLENSG00000099942.810261.3882014879.30230-0.536105.755703.07330K562KHSRP
CRKLENSG00000099942.820998.8850014808.196000.503806.437605.05770K562KIF1C
CRKLENSG00000099942.86367.828408598.24680-0.433203.305002.27490K562KRR1
CRKLENSG00000099942.822049.4532016589.008600.410406.603505.08510K562MBNL1
CRKLENSG00000099942.811470.2871014656.44840-0.3536010.055908.61840K562MTPAP
CRKLENSG00000099942.819372.0444011627.749500.736303.040902.10800K562NAA15
CRKLENSG00000099942.816844.1942010209.921500.722203.753902.55060K562PABPN1
CRKLENSG00000099942.818787.1707015118.039200.313404.042402.39590K562PCBP1
CRKLENSG00000099942.818440.0495013760.798500.422205.692604.28310K562PCBP2
CRKLENSG00000099942.819132.1639026383.14130-0.463608.385806.13940K562PNPT1
CRKLENSG00000099942.89739.5068011663.72130-0.260103.072702.22750K562POLR2G
CRKLENSG00000099942.87036.909908660.48000-0.299502.867201.94410K562PSIP1
CRKLENSG00000099942.810804.5917015026.14380-0.475808.212507.11000K562PTBP1
CRKLENSG00000099942.825693.6766029798.66870-0.213802.493901.48460K562PUM1
CRKLENSG00000099942.823542.6780029196.00660-0.310506.049304.61310K562PUM2
CRKLENSG00000099942.822413.0548013837.383500.6957011.8987010.82110K562PUS1
CRKLENSG00000099942.825730.8271013483.519500.9322012.9639011.67840K562RBM15
CRKLENSG00000099942.811529.0745015162.28000-0.395204.069802.71130K562NELFE
CRKLENSG00000099942.810221.316209078.577000.170902.972501.31590K562RPS10
CRKLENSG00000099942.88488.7915010739.72310-0.339302.583701.79580K562RPS19
CRKLENSG00000099942.88460.7555010392.51100-0.296703.310002.12510K562SAFB
CRKLENSG00000099942.818723.031009335.944401.003805.306203.47140K562SF1
CRKLENSG00000099942.817137.9712013165.918800.380303.028402.13310K562SF3B4
CRKLENSG00000099942.816764.0862010723.766500.644502.709301.49720K562SNRNP200
CRKLENSG00000099942.813898.3198016462.83720-0.244306.311104.96580K562SRPK2
CRKLENSG00000099942.812142.9716014730.66260-0.278703.273302.50820K562SRSF1
CRKLENSG00000099942.810020.3008011698.95190-0.223502.397401.63380K562SYNCRIP
CRKLENSG00000099942.812404.9198014908.32260-0.265202.145001.51700K562TARDBP
CRKLENSG00000099942.87236.425309305.60770-0.362803.107801.32350K562TFIP11
CRKLENSG00000099942.810781.4795014380.77880-0.415606.717905.35760K562TIA1
CRKLENSG00000099942.816560.3651012677.210300.385403.789002.84810K562U2AF2
CRKLENSG00000099942.814785.9464017266.89180-0.223804.536503.64040K562UPF1
CRKLENSG00000099942.822591.3130014030.975600.687103.422401.93120K562UTP18
CRKLENSG00000099942.88068.1072011001.91370-0.447504.931003.14070K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CRKL is not available on ENCORE database.





2 RBPs can affect the splicing of CRKL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECRKLENSG00000099942.8chr22+212880662128819421271721212725332130399821308037-0.051000.000500.01199excludedK562SF3B4
SECRKLENSG00000099942.8chr22+212884102128853221271721212725332130399821304215-0.065000.000000.00000excludedK562AQR
A3SSCRKLENSG00000099942.8chr22+2128804321288194212880662128819421271721212725330.056000.000000.00000longerK562AQR
MXECRKLENSG00000099942.8chr22+21288043212881942128841021288532212717212127253321303998213080370.061000.000000.000001includedK562AQR
MXECRKLENSG00000099942.8chr22+2128806621288532213039982130421521271721212725332130749321308035-0.057000.000000.000002includedK562AQR
MXECRKLENSG00000099942.8chr22+2130399821304215213054282130555321288410212885322130749321308035-0.109000.000000.000002includedK562AQR
MXECRKLENSG00000099942.8chr22+2130399821304215213054732130555321288410212885322130749321308035-0.112000.000000.000002includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CRKL is not avaliable on ENCORE database.