SPDL1

General Information

Gene Name       : SPDL1
Gene ID             : ENSG00000040275.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SPDL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPDL1ENSG00000040275.1642.6746.0144.34ENCSR000AEF
HepG2SPDL1ENSG00000040275.1619.9234.3427.13ENCSR985KAT
K562SPDL1ENSG00000040275.1633.3335.8134.57ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPDL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPDL1 RNA is bound by 3 proteins.  







eCLIP assay for SPDL1 is not avaliable on ENCORE database.





3 proteins are bound to SPDL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5169021209169021297+3'-UTR,CDS3.152336.05769K562ZNF622
chr5169021201169021299+3'-UTR,CDS,intron-Proximal3.893217.79255K562UCHL5
chr5169021585169021665+3'-UTR,CDS4.528925.14565K562UCHL5
chr5169021208169021299+3'-UTR,CDS,intron-Proximal3.345604.34695HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPDL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPDL1 is not available on ENCORE database.

  • 135 RBPs can affect the levels of SPDL1.  








The Knockdown/knockout RNA-Seq assay for SPDL1 is not available on ENCORE database.





135 RBPs can affect the gene expression of SPDL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPDL1ENSG00000040275.12298.29970558.42310-0.9046012.8937011.78470HepG2ACO1
SPDL1ENSG00000040275.12336.61210561.13010-0.737206.671405.53310HepG2AKAP8L
SPDL1ENSG00000040275.12242.94710406.14120-0.741304.888703.85730HepG2ASCC1
SPDL1ENSG00000040275.12421.91410859.04680-1.0258020.3200018.76920HepG2AUH
SPDL1ENSG00000040275.12283.59300663.51250-1.2263013.1021010.98970HepG2BCCIP
SPDL1ENSG00000040275.12216.52920576.52530-1.4128016.5878014.68700HepG2BCLAF1
SPDL1ENSG00000040275.12246.71160662.98430-1.4261021.3463019.92590HepG2BOP1
SPDL1ENSG00000040275.12341.68680588.28960-0.783907.085505.92580HepG2CALR
SPDL1ENSG00000040275.12643.92680897.47030-0.479002.783901.80560HepG2CCAR1
SPDL1ENSG00000040275.12255.83400385.86280-0.592903.310702.46960HepG2CIRBP
SPDL1ENSG00000040275.12261.96520558.40200-1.0919015.3081014.00730HepG2CKAP4
SPDL1ENSG00000040275.12333.98790608.64890-0.865808.237807.10400HepG2CPSF6
SPDL1ENSG00000040275.12318.71710488.04090-0.614703.133901.95740HepG2CPSF7
SPDL1ENSG00000040275.12367.02100834.90540-1.1858025.1638023.62660HepG2CELF1
SPDL1ENSG00000040275.12499.21990897.88180-0.8469018.3288016.73010HepG2DAZAP1
SPDL1ENSG00000040275.12299.57540427.88250-0.514303.014802.30930HepG2DDX21
SPDL1ENSG00000040275.12350.62550494.17950-0.495102.820801.41760HepG2DDX28
SPDL1ENSG00000040275.12226.05670470.19960-1.056609.323008.23200HepG2DDX3X
SPDL1ENSG00000040275.12277.43950652.37850-1.2335013.1979011.66570HepG2DDX55
SPDL1ENSG00000040275.12262.97940691.16780-1.3941011.387509.48150HepG2DDX59
SPDL1ENSG00000040275.12138.56480403.92260-1.5435014.8110013.53340HepG2DDX6
SPDL1ENSG00000040275.12335.58530467.63340-0.478702.427301.50840HepG2DHX30
SPDL1ENSG00000040275.12347.32060484.85170-0.481303.766102.95430HepG2DNAJC21
SPDL1ENSG00000040275.12314.05110480.54590-0.613706.747605.79230HepG2DNAJC2
SPDL1ENSG00000040275.12172.15780393.75400-1.193609.792407.81970HepG2AGO1
SPDL1ENSG00000040275.1287.31400388.28930-2.1528025.2269023.56540HepG2EIF2S1
SPDL1ENSG00000040275.12226.14900393.55780-0.799305.146203.94200HepG2EIF3D
SPDL1ENSG00000040275.12286.25000417.79930-0.545502.381501.74160HepG2EIF4B
SPDL1ENSG00000040275.12600.85340885.68330-0.559804.986403.91690HepG2EIF4G1
SPDL1ENSG00000040275.12517.52900848.45160-0.713207.701606.37290HepG2EIF4G2
SPDL1ENSG00000040275.12538.17860986.29030-0.8739016.1652014.90940HepG2ETF1
SPDL1ENSG00000040275.12275.04100407.59310-0.567503.839202.52500HepG2FASTKD2
SPDL1ENSG00000040275.12326.42660609.70630-0.901403.669102.49420HepG2FTO
SPDL1ENSG00000040275.12684.47200432.960300.660705.240204.30880HepG2FXR1
SPDL1ENSG00000040275.12251.93560401.62550-0.672804.095503.29520HepG2G3BP1
SPDL1ENSG00000040275.12339.68100689.93220-1.0223010.361609.17600HepG2GPKOW
SPDL1ENSG00000040275.12359.30600533.19500-0.569505.931204.56260HepG2HDGF
SPDL1ENSG00000040275.12283.66620489.49650-0.787106.488405.56000HepG2HNRNPA1
SPDL1ENSG00000040275.12498.89100825.10500-0.7259011.338909.68730HepG2HNRNPA2B1
SPDL1ENSG00000040275.12353.82740544.46620-0.621804.648603.76530HepG2HNRNPC
SPDL1ENSG00000040275.12364.86410561.75070-0.622606.396905.36840HepG2HNRNPF
SPDL1ENSG00000040275.12435.56900817.94820-0.9091015.3135013.83860HepG2HNRNPL
SPDL1ENSG00000040275.12212.49480658.41670-1.6316023.8077022.25610HepG2HNRNPLL
SPDL1ENSG00000040275.12356.97880540.86710-0.599406.549605.65080HepG2HNRNPU
SPDL1ENSG00000040275.12343.43790553.16840-0.687706.413305.35400HepG2IGF2BP1
SPDL1ENSG00000040275.12155.09560408.24040-1.3963013.7669012.39050HepG2IGF2BP2
SPDL1ENSG00000040275.12365.76850552.47930-0.595007.445806.30500HepG2ILF2
SPDL1ENSG00000040275.12454.11240947.51310-1.0611011.268109.58510HepG2LARP4
SPDL1ENSG00000040275.12326.80310563.00570-0.784706.938405.07340HepG2LIN28B
SPDL1ENSG00000040275.12626.16230433.111500.531703.430002.69940HepG2MAGOH
SPDL1ENSG00000040275.12594.74630435.532900.449402.366401.77960HepG2MATR3
SPDL1ENSG00000040275.12240.41080411.87560-0.776703.365902.20880HepG2METAP2
SPDL1ENSG00000040275.12282.57190406.64270-0.525102.893601.65070HepG2NAA15
SPDL1ENSG00000040275.12225.05980445.78990-0.986107.909006.86360HepG2NCBP2
SPDL1ENSG00000040275.12593.24530890.32950-0.585706.215505.07680HepG2NOL12
SPDL1ENSG00000040275.12252.00140599.09300-1.249309.029107.01470HepG2NONO
SPDL1ENSG00000040275.12403.48660583.82590-0.533003.685902.82440HepG2NSUN2
SPDL1ENSG00000040275.1270.62240171.71190-1.281805.684304.37760HepG2PABPC1
SPDL1ENSG00000040275.12193.57560396.99500-1.036208.543507.29130HepG2PABPC4
SPDL1ENSG00000040275.12377.60330535.37600-0.503704.491803.44230HepG2PARN
SPDL1ENSG00000040275.12262.12460486.17610-0.891205.958904.47990HepG2PCBP2
SPDL1ENSG00000040275.12386.52490482.41170-0.319701.978301.34640HepG2PPIL4
SPDL1ENSG00000040275.12795.87810511.084100.638903.801002.38210HepG2PRPF6
SPDL1ENSG00000040275.12246.30340503.21590-1.030709.369007.98370HepG2PRPF8
SPDL1ENSG00000040275.12382.87640849.85490-1.1503018.9462017.57140HepG2PUF60
SPDL1ENSG00000040275.12637.05970902.10860-0.501906.517605.68760HepG2PUM1
SPDL1ENSG00000040275.12654.64970901.48060-0.461604.755003.88770HepG2PUM2
SPDL1ENSG00000040275.12439.73720568.80480-0.371303.102502.45820HepG2PUS1
SPDL1ENSG00000040275.12291.64960404.61780-0.472302.951502.30990HepG2QKI
SPDL1ENSG00000040275.12266.40730469.14720-0.816403.906703.07380HepG2RAVER1
SPDL1ENSG00000040275.12357.83440640.40980-0.839708.005006.65050HepG2RBM15
SPDL1ENSG00000040275.12345.66680824.35830-1.2539024.4159023.18150HepG2RBM22
SPDL1ENSG00000040275.12239.13130367.21080-0.618804.088103.28220HepG2RBM25
SPDL1ENSG00000040275.12404.37630825.29740-1.029203.190901.44010HepG2RBM39
SPDL1ENSG00000040275.12644.12350415.770800.631406.732405.95230HepG2NELFE
SPDL1ENSG00000040275.12621.75390387.223000.683107.580006.63400HepG2RECQL
SPDL1ENSG00000040275.12209.83820605.07890-1.5278022.8890021.31660HepG2RPLP0
SPDL1ENSG00000040275.12249.99610460.88940-0.882505.517404.20630HepG2RPS10
SPDL1ENSG00000040275.12202.10540382.97560-0.922107.929906.95270HepG2RPS19
SPDL1ENSG00000040275.12404.35770596.24950-0.560303.798602.86500HepG2RPS2
SPDL1ENSG00000040275.12149.64110497.78060-1.7340020.3570018.59340HepG2RRP9
SPDL1ENSG00000040275.12340.27450481.67090-0.501304.427303.64560HepG2SAFB2
SPDL1ENSG00000040275.12204.13110384.33370-0.912907.000005.52200HepG2SERBP1
SPDL1ENSG00000040275.12292.62040651.69170-1.1552014.4958013.01590HepG2SF3B1
SPDL1ENSG00000040275.12468.33050814.77590-0.7989014.8346013.44090HepG2SLBP
SPDL1ENSG00000040275.12343.32020561.71770-0.710309.331608.26190HepG2SMN1
SPDL1ENSG00000040275.12291.96040478.48140-0.712704.416603.18850HepG2SMNDC1
SPDL1ENSG00000040275.12318.49990811.03730-1.348505.381803.39120HepG2SNRNP200
SPDL1ENSG00000040275.12443.54500725.12520-0.709104.204103.23370HepG2SNRNP70
SPDL1ENSG00000040275.12406.62780931.08630-1.1952028.8290027.65410HepG2SRFBP1
SPDL1ENSG00000040275.121010.03690405.988601.3148033.2135031.97250HepG2SRSF1
SPDL1ENSG00000040275.12475.60890701.25320-0.560203.464402.33120HepG2SRSF3
SPDL1ENSG00000040275.12480.60890839.04810-0.8039014.0337012.77540HepG2SRSF5
SPDL1ENSG00000040275.12269.69410551.88670-1.0330015.1004013.70050HepG2SRSF7
SPDL1ENSG00000040275.12173.50750330.28880-0.928708.879507.99010HepG2SRSF9
SPDL1ENSG00000040275.12611.77670808.41000-0.402104.185803.58240HepG2SSB
SPDL1ENSG00000040275.12519.81060954.28000-0.8764013.7378012.52570HepG2SUCLG1
SPDL1ENSG00000040275.12250.42180404.09750-0.690303.474202.43000HepG2SUPT6H
SPDL1ENSG00000040275.12220.29380649.42070-1.5597020.1194018.59410HepG2SUPV3L1
SPDL1ENSG00000040275.12190.97360641.80200-1.7488027.9199026.08480HepG2TARDBP
SPDL1ENSG00000040275.12320.50740193.636000.726902.636401.59110HepG2TBRG4
SPDL1ENSG00000040275.12139.65550435.27660-1.6401018.3714016.31020HepG2TFIP11
SPDL1ENSG00000040275.12154.59030525.58390-1.7655031.0871029.73860HepG2TIAL1
SPDL1ENSG00000040275.12192.48320530.24960-1.4619027.7595026.20980HepG2TRIM56
SPDL1ENSG00000040275.12249.84540944.13270-1.918009.034107.14450HepG2U2AF2
SPDL1ENSG00000040275.12590.95400878.69020-0.572304.324403.26500HepG2UBE2L3
SPDL1ENSG00000040275.12165.20780383.62460-1.2154011.5462010.01500HepG2UCHL5
SPDL1ENSG00000040275.12203.88410463.27670-1.1841017.3479015.89290HepG2UPF1
SPDL1ENSG00000040275.12386.82240594.63890-0.620303.290602.19170HepG2UPF2
SPDL1ENSG00000040275.12363.34320476.17300-0.390202.708501.67000HepG2UTP18
SPDL1ENSG00000040275.12191.01690509.51360-1.4154026.7671025.50980HepG2ZNF622
SPDL1ENSG00000040275.12634.66420845.29750-0.413503.128602.53100K562AGGF1
SPDL1ENSG00000040275.12466.13070879.54140-0.916008.208207.02260K562AKAP8L
SPDL1ENSG00000040275.121053.464401431.62460-0.442502.978802.37340K562AQR
SPDL1ENSG00000040275.12654.66830922.79600-0.495204.340803.16760K562ATP5C1
SPDL1ENSG00000040275.12614.81080821.75450-0.418603.939002.31880K562BCCIP
SPDL1ENSG00000040275.12614.91790794.09310-0.368903.476702.39550K562BCLAF1
SPDL1ENSG00000040275.12629.45330834.00890-0.406002.691901.83110K562BOP1
SPDL1ENSG00000040275.12698.54550920.49520-0.398103.004201.66530K562CIRBP
SPDL1ENSG00000040275.12979.064001263.10850-0.367502.471601.42980K562CPEB4
SPDL1ENSG00000040275.12608.95310886.77010-0.542205.540704.43840K562CPSF6
SPDL1ENSG00000040275.12444.28400602.43790-0.439303.098301.97360K562CSTF2
SPDL1ENSG00000040275.121719.914702132.03310-0.309902.735001.76510K562CELF1
SPDL1ENSG00000040275.12655.39520830.73910-0.342002.954001.70240K562DDX21
SPDL1ENSG00000040275.12705.12160504.198600.483803.859602.89530K562EIF4A3
SPDL1ENSG00000040275.12738.170701024.69140-0.473204.140403.08970K562FIP1L1
SPDL1ENSG00000040275.12714.77350902.30760-0.336102.107201.35610K562FMR1
SPDL1ENSG00000040275.12975.09200524.346300.8949016.6583015.28420K562FXR1
SPDL1ENSG00000040275.12857.35670620.561200.466202.728202.02760K562G3BP2
SPDL1ENSG00000040275.12524.27870846.63060-0.691407.397006.09580K562GPKOW
SPDL1ENSG00000040275.12619.66850858.53550-0.470402.944501.87660K562IGF2BP2
SPDL1ENSG00000040275.12612.47730873.38100-0.512004.699503.06080K562IGF2BP3
SPDL1ENSG00000040275.12731.94030933.51460-0.350902.488501.71020K562KIF1C
SPDL1ENSG00000040275.12453.31730722.96040-0.673404.441703.22770K562KRR1
SPDL1ENSG00000040275.12459.56040688.29270-0.582804.433302.49650K562LIN28B
SPDL1ENSG00000040275.121223.97650902.618800.439303.249302.33090K562MAGOH
SPDL1ENSG00000040275.12687.03740914.19510-0.412105.337104.34960K562NSUN2
SPDL1ENSG00000040275.12702.69750543.266700.371102.811902.00310K562POLR2G
SPDL1ENSG00000040275.12857.838501163.19560-0.439303.822702.83620K562PPIG
SPDL1ENSG00000040275.12548.007301223.89640-1.159203.287501.64430K562PPP1R8
SPDL1ENSG00000040275.12872.62130615.773100.502903.963003.06620K562PRPF8
SPDL1ENSG00000040275.12387.00710608.50400-0.652905.545904.20150K562PSIP1
SPDL1ENSG00000040275.122619.929102012.371600.380504.867003.42100K562PUM1
SPDL1ENSG00000040275.12552.48520849.91970-0.621404.752103.99500K562RBM15
SPDL1ENSG00000040275.12613.87400841.04840-0.454203.673402.69330K562RBM22
SPDL1ENSG00000040275.12360.06510589.25380-0.710603.316501.84660K562RBM25
SPDL1ENSG00000040275.12434.61730555.15210-0.353102.191701.31310K562RCC2
SPDL1ENSG00000040275.12455.90440645.88840-0.502602.561601.74150K562SF3B4
SPDL1ENSG00000040275.12374.46190526.27240-0.491003.137602.02810K562SRFBP1
SPDL1ENSG00000040275.121141.22200859.642500.408703.873203.04250K562SRSF1
SPDL1ENSG00000040275.12581.77860811.77540-0.480603.876302.59640K562SRSF5
SPDL1ENSG00000040275.12566.85880741.32440-0.387103.425002.11330K562SRSF7
SPDL1ENSG00000040275.12895.12080544.894300.716009.480307.95420K562SYNCRIP
SPDL1ENSG00000040275.12532.15560870.09450-0.709306.737305.59050K562TARDBP
SPDL1ENSG00000040275.12420.58000585.28260-0.476802.829701.88300K562TIAL1
SPDL1ENSG00000040275.12600.22030823.39660-0.456103.562202.29210K562TRA2A
SPDL1ENSG00000040275.12335.64540621.75480-0.889409.230107.27780K562TRIM56
SPDL1ENSG00000040275.12795.88560602.215800.402202.445801.42980K562U2AF1
SPDL1ENSG00000040275.12878.12810621.732000.498002.926102.09990K562U2AF2
SPDL1ENSG00000040275.12655.98250829.43340-0.338502.467301.63900K562WDR3
SPDL1ENSG00000040275.121023.35150862.524100.246602.356501.57090K562WDR43
SPDL1ENSG00000040275.121168.495701612.97530-0.465103.500502.50990K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPDL1 is not available on ENCORE database.





15 RBPs can affect the splicing of SPDL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPDL1ENSG00000040275.12chr5+1690142021690143761690106391690108931690153971690155790.170000.000180.02237includedHepG2G3BP1
SESPDL1ENSG00000040275.12chr5+1690142021690143761690106391690108931690153971690155790.192000.000000.00050includedHepG2RBM22
SESPDL1ENSG00000040275.12chr5+1690142021690143761690106391690108931690153971690155790.299000.000000.00000includedHepG2U2AF1
SESPDL1ENSG00000040275.12chr5+1690177591690178331690153971690155791690180511690182280.061000.003420.03411includedK562AQR
SESPDL1ENSG00000040275.12chr5+169021397169021496169020357169020552169021574169021685-0.091000.003180.03211excludedK562AQR
SESPDL1ENSG00000040275.12chr5+169014202169014376169010639169010893169015397169015579-0.090000.001670.06569excludedHepG2SFPQ
SESPDL1ENSG00000040275.12chr5+1690177561690178331690154551690155791690180511690182280.162000.001930.06830includedHepG2MATR3
SESPDL1ENSG00000040275.12chr5+1690142021690143761690106391690108931690153971690155790.250000.000000.00008includedHepG2MATR3
SESPDL1ENSG00000040275.12chr5+1690142021690143761690106391690108931690153971690155790.283000.000000.00014includedK562U2AF1
SESPDL1ENSG00000040275.12chr5+1690110911690111701690107901690108931690153971690155790.209000.000780.06232includedHepG2DDX6
SESPDL1ENSG00000040275.12chr5+169014202169014376169010639169010893169015397169015579-0.085000.000450.06269excludedK562HNRNPM
SESPDL1ENSG00000040275.12chr5+169017756169017833169015538169015579169018051169018228-0.139000.000730.07054excludedHepG2LARP4
SESPDL1ENSG00000040275.12chr5+169014202169014376169010639169010893169015397169015579-0.056000.000660.04763excludedK562HNRNPL
SESPDL1ENSG00000040275.12chr5+1690177591690178331690153971690155791690180511690182280.079000.000120.07321includedK562PUM2
SESPDL1ENSG00000040275.12chr5+169014202169014376169010639169010893169015397169015579-0.082000.000810.08155excludedHepG2RBFOX2
SESPDL1ENSG00000040275.12chr5+1690177591690178331690153971690155791690180511690182280.146000.000030.00233includedK562TARDBP
SESPDL1ENSG00000040275.12chr5+1690142021690143761690106391690108931690153971690155790.159000.000010.00049includedK562TARDBP
SESPDL1ENSG00000040275.12chr5+169014202169014376169010639169010893169015397169015579-0.090000.000220.01143excludedK562HNRNPU
SESPDL1ENSG00000040275.12chr5+1690142021690143761690106391690108931690153971690155790.307000.000000.00013includedK562HNRNPC
SESPDL1ENSG00000040275.12chr5+1690177591690178331690153971690155791690180511690182280.226000.000020.00069includedK562HNRNPC
A3SSSPDL1ENSG00000040275.12chr5+1690235411690237051690235641690237051690215811690216850.133000.000000.00000longerK562AQR
A3SSSPDL1ENSG00000040275.12chr5+1690211151690212981690211481690212981690203571690205520.057000.000060.00057longerK562AQR
A3SSSPDL1ENSG00000040275.12chr5+1690254541690256971690254791690256971690235641690237050.074000.000800.00570longerK562AQR
A3SSSPDL1ENSG00000040275.12chr5+169015397169015579169015455169015579169010759169010893-0.093000.009460.05043shorterK562AQR
A3SSSPDL1ENSG00000040275.12chr5+169023564169023705169023588169023705169021581169021685-0.123000.001640.01079shorterK562AQR
MXESPDL1ENSG00000040275.12chr5+169015397169015579169017759169017833169010791169010893169018051169018228-0.138000.001030.029892includedHepG2MATR3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPDL1 is not avaliable on ENCORE database.