TIMP3

General Information

Gene Name       : TIMP3
Gene ID             : ENSG00000100234.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TIMP3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TIMP3ENSG00000100234.110.000.000.00ENCSR000AEF
HepG2TIMP3ENSG00000100234.1150.2257.5453.88ENCSR985KAT
K562TIMP3ENSG00000100234.110.180.190.18ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TIMP3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TIMP3 RNA is bound by 18 proteins.  







eCLIP assay for TIMP3 is not avaliable on ENCORE database.





18 proteins are bound to TIMP3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr223325572633255764+3'-UTR3.356416.05006HepG2PCBP1
chr223325663333256751+3'-UTR4.1858916.44920HepG2UPF1
chr223325614433256213+3'-UTR4.1663510.62478HepG2LIN28B
chr223325813933258172+3'-UTR4.100429.51202HepG2IGF2BP3
chr223325817233258200+3'-UTR3.384204.36257HepG2IGF2BP3
chr223325533633255407+3'-UTR,CDS3.8260916.77435HepG2RPS3
chr223325571633255790+3'-UTR5.3468944.28001HepG2PCBP2
chr223325827833258339+3'-UTR3.202014.57410HepG2IGF2BP3
chr223325811733258139+3'-UTR3.905583.77064HepG2IGF2BP3
chr223325844933258521+3'-UTR4.187903.55864HepG2IGF2BP3
chr223325852533258572+3'-UTR3.513724.34898HepG2IGF2BP1
chr223325656333256650+3'-UTR5.001347.75438HepG2IGF2BP3
chr223325889233258982+3'-UTR3.438206.67015HepG2KHSRP
chr223325594733255995+3'-UTR3.778995.14779HepG2FAM120A
chr223325534933255415+3'-UTR,CDS3.6986210.25631HepG2SND1
chr223325889733259014+3'-UTR5.8709724.81834HepG2FUBP3
chr223325535233255407+3'-UTR,CDS4.8370951.79431HepG2PCBP2
chr223325825633258313+3'-UTR3.346458.05942HepG2UPF1
chr223325552833255609+3'-UTR3.148234.75233HepG2IGF2BP3
chr223325603833256080+3'-UTR3.618874.09794HepG2IGF2BP1
chr223325585533255928+3'-UTR5.4755227.07376HepG2LIN28B
chr223325701133257052+3'-UTR4.386535.03940HepG2LIN28B
chr223325572633255762+3'-UTR3.681343.34998HepG2IGF2BP3
chr223325570133255790+3'-UTR4.5885520.73091HepG2UPF1
chr223325535033255436+3'-UTR,CDS4.3104428.42580HepG2PCBP1
chr223325602233256110+3'-UTR3.230396.62969HepG2AKAP1
chr223325625433256297+3'-UTR3.307716.87401HepG2UPF1
chr223325844633258522+3'-UTR3.8853110.31850HepG2IGF2BP1
chr223325540733255463+3'-UTR5.8660347.88904HepG2PCBP2
chr223325647133256508+3'-UTR3.044385.36275HepG2FUBP3
chr223325655233256618+3'-UTR3.148714.41684HepG2FAM120A
chr223325545733255514+3'-UTR3.559823.68079HepG2FUBP3
chr223325655133256635+3'-UTR5.243109.03683HepG2IGF2BP1
chr223325819533258256+3'-UTR3.566226.15198HepG2UPF1
chr223325895333259001+3'-UTR4.158093.88726HepG2TIAL1
chr223325599533256079+3'-UTR3.316555.17377HepG2FAM120A
chr223325811533258218+3'-UTR4.0739114.14542HepG2IGF2BP1
chr223325676833256822+3'-UTR3.880734.39727HepG2LIN28B
chr223325852133258568+3'-UTR3.810453.73561HepG2IGF2BP3
chr223325595633256077+3'-UTR4.2897221.63910HepG2UPF1
chr223325785633257902+3'-UTR3.350094.46783HepG2FUBP3
chr223325812933258142+3'-UTR4.460243.45012HepG2UPF1
chr223325875833258796+3'-UTR3.671205.36498HepG2UPF1
chr223319792733197998+5'-UTR,CDS4.6287025.37843HepG2RPS3
chr223319784033197892+5'-UTR3.069885.23152HepG2NOL12
chr223319773833197854+5'-UTR4.7936944.63077HepG2RPS3
chr223319793833197995+5'-UTR,CDS3.9915634.51097HepG2DDX3X
chr223319774233197847+5'-UTR3.9834377.75360HepG2DDX3X
chr223319774633197805+5'-UTR3.006016.26081HepG2PCBP1
chr223319784733197938+5'-UTR4.8834074.49283HepG2DDX3X
chr223319785433197927+5'-UTR5.9511330.80676HepG2RPS3
chr223319806333198100+CDS5.1743814.47646HepG2RPS3
chr223325400333254011+CDS,intron-Proximal4.027386.92877HepG2SND1
chr223325397133254079+CDS,intron-Proximal3.769515.40420HepG2AQR
chr223319800933198069+CDS4.5816633.15656HepG2DDX3X
chr223325401133254063+CDS4.9077823.34767HepG2SND1
chr223325327633253328+CDS4.8973917.11207HepG2SND1
chr223325332833253391+CDS,intron-Proximal4.229053.93614HepG2AQR
chr223325323533253276+CDS,intron-Proximal3.968048.34613HepG2SND1
chr223325516733255197+CDS3.330226.62503HepG2SND1
chr223325406333254121+CDS4.3821223.01499HepG2SND1
chr223324539633245509+CDS,intron-Proximal3.377575.33249HepG2AQR
chr223319810733198148+CDS,intron-Proximal4.654204.62947HepG2AQR
chr223325332833253347+CDS4.1227010.93642HepG2SND1
chr223325523233255333+CDS5.7172916.99768HepG2RPS3
chr223324543633245503+CDS,intron-Proximal4.9756218.53538HepG2RPS3
chr223325526233255349+CDS4.9461527.95664HepG2SND1
chr223325519733255236+CDS3.614048.01308HepG2SND1
chr223325523633255262+CDS4.5389210.07222HepG2SND1
chr223320282733202887+intron-Distal4.2538210.96443HepG2PTBP1
chr223319932133199442+intron-Distal3.815967.47109HepG2FAM120A
chr223324805533248190+intron-Distal4.571074.55788HepG2QKI
chr223323972233239858+intron-Distal4.571074.55788HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TIMP3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TIMP3 is not available on ENCORE database.

  • 137 RBPs can affect the levels of TIMP3.  








The Knockdown/knockout RNA-Seq assay for TIMP3 is not available on ENCORE database.





137 RBPs can affect the gene expression of TIMP3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TIMP3ENSG00000100234.112054.979404109.97710-1.0000024.0539021.45570HepG2AATF
TIMP3ENSG00000100234.112984.610205308.21670-0.8307013.5580011.74210HepG2ABCF1
TIMP3ENSG00000100234.116072.732904211.283300.5280018.5457017.27130HepG2ACO1
TIMP3ENSG00000100234.115754.946303644.799200.658909.799108.07620HepG2ADAR
TIMP3ENSG00000100234.113097.255007059.12280-1.1885022.1459020.79750HepG2AKAP1
TIMP3ENSG00000100234.113556.479005331.74930-0.584206.188704.66230HepG2AKAP8
TIMP3ENSG00000100234.112341.781804230.95470-0.8534034.1924032.01120HepG2AKAP8L
TIMP3ENSG00000100234.113855.845305840.69840-0.599107.566706.29810HepG2ASCC1
TIMP3ENSG00000100234.112804.965003985.56320-0.5068012.4626011.19090HepG2AUH
TIMP3ENSG00000100234.111859.772402967.69700-0.674207.079605.54160HepG2BCCIP
TIMP3ENSG00000100234.116911.652702578.717101.4223034.3674031.80440HepG2BCLAF1
TIMP3ENSG00000100234.117545.031603976.423400.9240023.7788020.64660HepG2BUD13
TIMP3ENSG00000100234.113277.720706181.35930-0.9152011.697509.73660HepG2CCAR1
TIMP3ENSG00000100234.117360.839405549.108500.407504.074403.14580HepG2CIRBP
TIMP3ENSG00000100234.113331.979504210.23050-0.337508.304307.27280HepG2CKAP4
TIMP3ENSG00000100234.111265.715304027.00760-1.6698025.0193022.78900HepG2CNOT7
TIMP3ENSG00000100234.111944.060102672.76880-0.459304.821803.93510HepG2CPSF6
TIMP3ENSG00000100234.1110817.442604370.661801.3073049.1343045.80250HepG2CPSF7
TIMP3ENSG00000100234.119526.719803737.741401.3497078.9752075.09280HepG2YBX3
TIMP3ENSG00000100234.111429.079201833.15520-0.359202.937901.83150HepG2CSTF2
TIMP3ENSG00000100234.114270.083705002.81160-0.228502.904102.24850HepG2CELF1
TIMP3ENSG00000100234.111767.948305378.94380-1.60520154.07530150.46800HepG2DAZAP1
TIMP3ENSG00000100234.114571.916003894.770500.231204.072803.08430HepG2DDX19B
TIMP3ENSG00000100234.113176.688604534.09350-0.513307.299606.25010HepG2DDX21
TIMP3ENSG00000100234.113615.496702730.167200.405102.671001.40340HepG2DDX27
TIMP3ENSG00000100234.111594.929406761.81990-2.0839072.2003069.39320HepG2DDX3X
TIMP3ENSG00000100234.117247.314705561.338500.381904.227802.64690HepG2DDX47
TIMP3ENSG00000100234.118118.055102917.851801.476108.966707.66580HepG2DDX55
TIMP3ENSG00000100234.115573.803703035.141700.876806.600505.12280HepG2DDX59
TIMP3ENSG00000100234.118850.674205809.216000.607306.621405.69800HepG2DDX6
TIMP3ENSG00000100234.112121.939404029.02140-0.9250039.4946037.71900HepG2DKC1
TIMP3ENSG00000100234.111750.906703670.05650-1.0677041.8957039.59740HepG2DNAJC21
TIMP3ENSG00000100234.114069.308903637.831100.161602.336401.72710HepG2DNAJC2
TIMP3ENSG00000100234.112918.968204100.18980-0.490205.419004.16620HepG2EEF2
TIMP3ENSG00000100234.112469.664203418.10790-0.468904.155802.79380HepG2EFTUD2
TIMP3ENSG00000100234.113632.901005583.87250-0.620107.844506.88100HepG2EIF2S1
TIMP3ENSG00000100234.113421.772804281.97230-0.323503.796902.55570HepG2EIF3G
TIMP3ENSG00000100234.114110.265105306.92260-0.368607.698006.43180HepG2EIF4G1
TIMP3ENSG00000100234.112830.305205083.64480-0.8449010.945509.38420HepG2EIF4G2
TIMP3ENSG00000100234.112067.635502974.80780-0.524808.780306.66880HepG2FAM120A
TIMP3ENSG00000100234.115437.659103515.665500.629103.671001.32530HepG2FASTKD1
TIMP3ENSG00000100234.112746.661704321.02910-0.6537011.928409.83540HepG2FASTKD2
TIMP3ENSG00000100234.114082.719302428.689400.7493010.271808.11030HepG2FKBP4
TIMP3ENSG00000100234.11912.951002677.45270-1.5523011.912209.87130HepG2FTO
TIMP3ENSG00000100234.112540.225106226.76600-1.2935031.4034029.39140HepG2FXR1
TIMP3ENSG00000100234.111610.539705775.72430-1.8425052.8029050.09200HepG2G3BP1
TIMP3ENSG00000100234.112434.106202963.53670-0.283902.162501.37630HepG2GEMIN5
TIMP3ENSG00000100234.111769.585603654.58140-1.0463019.9366017.26030HepG2GNB2L1
TIMP3ENSG00000100234.117135.150203029.656401.2357026.3144024.57440HepG2GPKOW
TIMP3ENSG00000100234.111703.695603727.77680-1.1296013.9443011.49730HepG2GRSF1
TIMP3ENSG00000100234.115332.756803705.218600.525207.879506.87280HepG2HNRNPA1
TIMP3ENSG00000100234.119836.098304943.551500.992408.856807.36470HepG2HNRNPA2B1
TIMP3ENSG00000100234.112316.938703324.98670-0.521104.165302.43500HepG2HNRNPAB
TIMP3ENSG00000100234.112078.787504121.43130-0.9874023.4458021.65460HepG2HNRNPC
TIMP3ENSG00000100234.114757.136302938.162900.6951022.6474020.87260HepG2HNRNPF
TIMP3ENSG00000100234.114265.838805849.64460-0.455505.480104.52240HepG2HNRNPK
TIMP3ENSG00000100234.115708.749802891.269200.9814020.0822018.62650HepG2HNRNPLL
TIMP3ENSG00000100234.112661.924003697.62820-0.474107.011305.59990HepG2HNRNPM
TIMP3ENSG00000100234.112322.209504094.17840-0.8181032.7002030.81460HepG2HNRNPU
TIMP3ENSG00000100234.114336.471505806.04490-0.421003.089001.78020HepG2HSPD1
TIMP3ENSG00000100234.114675.092302893.222200.692209.645108.37030HepG2IGF2BP1
TIMP3ENSG00000100234.112407.357805510.14900-1.194607.008005.48410HepG2IGF2BP3
TIMP3ENSG00000100234.113127.630404182.05730-0.4191012.9774011.52050HepG2ILF2
TIMP3ENSG00000100234.112473.166703925.82820-0.666605.468303.57500HepG2ILF3
TIMP3ENSG00000100234.113223.700203849.55550-0.256005.024103.65740HepG2KIF1C
TIMP3ENSG00000100234.114287.060205801.19110-0.436402.966101.67400HepG2KRR1
TIMP3ENSG00000100234.112372.119703580.19850-0.593908.759506.85510HepG2LARP7
TIMP3ENSG00000100234.112612.863103759.47480-0.524906.683404.84350HepG2LIN28B
TIMP3ENSG00000100234.113577.276206263.64790-0.8081011.2971010.08580HepG2MATR3
TIMP3ENSG00000100234.115842.537104337.212200.429705.656004.53640HepG2MSI2
TIMP3ENSG00000100234.114795.824202949.014400.701405.609204.20330HepG2MTPAP
TIMP3ENSG00000100234.116798.695503642.143200.9004021.5998018.46980HepG2NAA15
TIMP3ENSG00000100234.114842.467206411.06260-0.404803.583802.86700HepG2NCBP2
TIMP3ENSG00000100234.114634.002503237.269300.517406.871104.61150HepG2NIP7
TIMP3ENSG00000100234.114100.373505333.76600-0.379405.851104.74580HepG2NOL12
TIMP3ENSG00000100234.119234.449402563.761301.8487077.5164074.73740HepG2NSUN2
TIMP3ENSG00000100234.117073.881103680.584200.942505.420404.14470HepG2PABPC1
TIMP3ENSG00000100234.113948.953705708.87550-0.531705.788704.75710HepG2PABPC4
TIMP3ENSG00000100234.111469.884504052.45980-1.4631077.4219074.41820HepG2PARN
TIMP3ENSG00000100234.119284.768403651.669401.3462044.5504041.78280HepG2PPIL4
TIMP3ENSG00000100234.113821.242105778.28190-0.596604.359602.84940HepG2PRPF6
TIMP3ENSG00000100234.111371.747702250.95000-0.714508.842607.48670HepG2PRPF8
TIMP3ENSG00000100234.112379.052605833.22490-1.2939081.1300079.14640HepG2PTBP1
TIMP3ENSG00000100234.114099.026705091.63140-0.312803.198002.56360HepG2PUF60
TIMP3ENSG00000100234.111669.299005405.09090-1.69510181.05410178.14660HepG2PUM1
TIMP3ENSG00000100234.114277.050705401.08110-0.336604.462903.62270HepG2PUM2
TIMP3ENSG00000100234.113262.803804289.44510-0.394709.896908.85390HepG2PUS1
TIMP3ENSG00000100234.115340.866606317.57540-0.242302.984402.34000HepG2QKI
TIMP3ENSG00000100234.112472.916503824.53010-0.6291010.805009.92820HepG2RBM22
TIMP3ENSG00000100234.117517.861005733.587300.390805.332604.42530HepG2RBM25
TIMP3ENSG00000100234.111199.980704317.10110-1.8471061.9122058.22690HepG2RBM27
TIMP3ENSG00000100234.114914.499303505.673100.487305.123703.67050HepG2RCC2
TIMP3ENSG00000100234.114948.355506491.83830-0.391709.484608.59130HepG2NELFE
TIMP3ENSG00000100234.115410.220006046.23060-0.160302.065801.52310HepG2RECQL
TIMP3ENSG00000100234.115019.604903165.562900.665006.303205.33100HepG2RPLP0
TIMP3ENSG00000100234.111535.549803238.73190-1.0767029.2933027.65150HepG2RPS19
TIMP3ENSG00000100234.112283.101103981.57700-0.8023013.5852011.91000HepG2RPS2
TIMP3ENSG00000100234.112418.643504064.25520-0.7488011.590109.40560HepG2RPS5
TIMP3ENSG00000100234.113872.846705770.12740-0.575204.046602.18260HepG2RTF1
TIMP3ENSG00000100234.113080.752703646.01120-0.243004.091703.33500HepG2SAFB2
TIMP3ENSG00000100234.112568.925103250.53930-0.339502.873601.91570HepG2SERBP1
TIMP3ENSG00000100234.115704.865502861.707300.9952023.3965021.57270HepG2SF3B1
TIMP3ENSG00000100234.1110487.438504882.284801.10290100.6133097.88740HepG2SLBP
TIMP3ENSG00000100234.113530.121204251.80500-0.268406.199405.29700HepG2SMN1
TIMP3ENSG00000100234.112765.880505406.45990-0.9669011.813509.75970HepG2SMNDC1
TIMP3ENSG00000100234.113595.258804319.73980-0.264804.287603.70360HepG2SRFBP1
TIMP3ENSG00000100234.113470.358406339.06950-0.8692046.2010044.77960HepG2SRSF1
TIMP3ENSG00000100234.112851.944805027.36340-0.8179033.9295032.08410HepG2SRSF5
TIMP3ENSG00000100234.114127.046202886.750000.5156012.7189011.41400HepG2SRSF7
TIMP3ENSG00000100234.113619.360305157.15630-0.5108015.9074014.77930HepG2SRSF9
TIMP3ENSG00000100234.11925.749103750.68570-2.0185089.0038087.15890HepG2SSB
TIMP3ENSG00000100234.112192.954005784.08400-1.3992029.6372026.33410HepG2SSRP1
TIMP3ENSG00000100234.119784.805504957.196100.9809011.266108.98110HepG2SUB1
TIMP3ENSG00000100234.112713.167605717.39530-1.0754072.9931070.64560HepG2SUCLG1
TIMP3ENSG00000100234.114449.136805856.47770-0.396502.611401.32740HepG2SUGP2
TIMP3ENSG00000100234.115743.303303618.627000.6663012.9664011.04620HepG2SUPT6H
TIMP3ENSG00000100234.114720.907602904.694800.700608.876507.77730HepG2SUPV3L1
TIMP3ENSG00000100234.113991.163102818.450900.501806.227205.19960HepG2TARDBP
TIMP3ENSG00000100234.112736.014405681.30800-1.054107.050305.43090HepG2TBRG4
TIMP3ENSG00000100234.113153.020301946.926300.695408.735707.16280HepG2TFIP11
TIMP3ENSG00000100234.111608.855003978.03200-1.3060050.9757049.32870HepG2TIAL1
TIMP3ENSG00000100234.113866.139205325.72260-0.462103.081401.53150HepG2TRA2A
TIMP3ENSG00000100234.111822.535602644.82350-0.537204.466402.48050HepG2TROVE2
TIMP3ENSG00000100234.113641.121004974.47050-0.450206.605105.16930HepG2TUFM
TIMP3ENSG00000100234.1110822.000504839.299201.161004.322503.07770HepG2U2AF2
TIMP3ENSG00000100234.111289.569301715.90510-0.412103.270002.44650HepG2UCHL5
TIMP3ENSG00000100234.113550.252804761.99580-0.4236010.576909.37100HepG2UPF1
TIMP3ENSG00000100234.115640.074904597.529600.294805.965605.14250HepG2UTP3
TIMP3ENSG00000100234.112624.948005833.28910-1.1520015.5214013.25870HepG2XRCC6
TIMP3ENSG00000100234.117421.143005237.292900.5027022.5029021.31310HepG2ZNF622
TIMP3ENSG00000100234.1141.4382016.006801.372202.348901.81870K562AGGF1
TIMP3ENSG00000100234.1114.6355051.84880-1.824804.068303.00800K562BOP1
TIMP3ENSG00000100234.1141.9214017.927201.225402.224801.45070K562DKC1
TIMP3ENSG00000100234.1145.8769010.216402.166804.379202.15360K562DNAJC2
TIMP3ENSG00000100234.1174.9983032.366601.212303.625702.82130K562EIF2S2
TIMP3ENSG00000100234.112.8095016.07480-2.516402.335301.77110K562FXR1
TIMP3ENSG00000100234.1112.9769043.13680-1.733003.246802.43060K562GRSF1
TIMP3ENSG00000100234.1155.4784014.631801.922705.526504.03090K562HNRNPA1
TIMP3ENSG00000100234.114.7730025.48610-2.416802.970602.00300K562HNRNPM
TIMP3ENSG00000100234.1164.2159019.803401.697104.525103.30310K562MBNL1
TIMP3ENSG00000100234.1111.9291037.44920-1.650402.844302.02460K562MTPAP
TIMP3ENSG00000100234.1139.9747013.880501.525902.329001.53600K562NAA15
TIMP3ENSG00000100234.113.9554016.63370-2.072202.126501.53130K562PTBP1
TIMP3ENSG00000100234.1164.4810023.540701.453603.282301.60790K562SBDS
TIMP3ENSG00000100234.1144.8893014.991101.582202.939601.95900K562TRIM56
TIMP3ENSG00000100234.1113.0876044.10950-1.752903.858103.02170K562UPF1
TIMP3ENSG00000100234.119.2883037.74180-2.022703.901202.85490K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TIMP3 is not available on ENCORE database.






No RBPs affect the alternative splcing events of TIMP3 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for TIMP3 is not avaliable on ENCORE database.