TMEM143

General Information

Gene Name       : TMEM143
Gene ID             : ENSG00000161558.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM143)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM143ENSG00000161558.102.084.733.41ENCSR000AEF
HepG2TMEM143ENSG00000161558.1010.995.328.16ENCSR985KAT
K562TMEM143ENSG00000161558.103.373.363.37ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM143 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM143 RNA is bound by 8 proteins.  







eCLIP assay for TMEM143 is not avaliable on ENCORE database.





8 proteins are bound to TMEM143 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194884595048846062-3'-UTR,CDS,intron-Distal,intron-Proximal4.080314.28220HepG2GRWD1
chr194884842948848578-3'-UTR,CDS,intron-Distal,intron-Proximal4.139044.04622HepG2GRWD1
chr194883653948836587-CDS,intron-Distal4.651934.73643HepG2DDX59
chr194884517348845253-intron-Distal3.527095.22214K562ILF3
chr194884526448845385-intron-Distal4.492295.31936HepG2HNRNPK
chr194883670048836849-intron-Distal3.837873.06617K562HNRNPK
chr194884527248845378-intron-Distal6.9604431.50981HepG2PCBP2
chr194884652648846577-intron-Distal,intron-Proximal4.130253.64476HepG2PRPF8
chr194884647048846526-intron-Distal,intron-Proximal3.596166.55814HepG2PRPF8
chr194884526348845324-intron-Distal3.482794.34776K562ILF3
chr194884527648845384-intron-Distal3.704133.48399HepG2CSTF2T
chr194886526348865370-intron-Distal5.188868.32644HepG2HNRNPL
chr194884509448845173-intron-Distal3.823336.14186K562ILF3
chr194884525348845397-intron-Distal5.9240910.17440HepG2DDX59
chr194884507148845189-intron-Distal4.222464.70168K562CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM143 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM143 is not available on ENCORE database.

  • 78 RBPs can affect the levels of TMEM143.  








The Knockdown/knockout RNA-Seq assay for TMEM143 is not available on ENCORE database.





78 RBPs can affect the gene expression of TMEM143 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM143ENSG00000161558.6104.60000240.08690-1.1987010.515109.48920HepG2ACO1
TMEM143ENSG00000161558.6163.02190249.36730-0.613202.355801.86040HepG2AKAP1
TMEM143ENSG00000161558.6140.85090241.19190-0.776005.163904.14470HepG2AKAP8L
TMEM143ENSG00000161558.6149.66030274.08160-0.872906.464205.48440HepG2AUH
TMEM143ENSG00000161558.692.47940262.31510-1.5041012.1563011.02200HepG2BOP1
TMEM143ENSG00000161558.6128.01870250.50270-0.968506.204205.10970HepG2CALR
TMEM143ENSG00000161558.6124.37960240.00710-0.948307.319206.33330HepG2CKAP4
TMEM143ENSG00000161558.694.80060159.86560-0.753902.648401.33620HepG2CSTF2T
TMEM143ENSG00000161558.6159.93950249.46550-0.641303.651002.93310HepG2CELF1
TMEM143ENSG00000161558.693.96060168.59240-0.843403.841502.75370HepG2DDX24
TMEM143ENSG00000161558.6160.18160238.87310-0.576502.327501.74870HepG2DDX3X
TMEM143ENSG00000161558.6101.03120205.20150-1.022204.898204.09710HepG2DDX6
TMEM143ENSG00000161558.675.51500158.64990-1.071004.738403.28650HepG2AGO1
TMEM143ENSG00000161558.6105.95230197.26060-0.896704.000303.29660HepG2EIF2S1
TMEM143ENSG00000161558.6304.92600217.994000.484102.058301.50450HepG2EIF4A3
TMEM143ENSG00000161558.6184.19170264.63170-0.522802.758101.92240HepG2EIF4G1
TMEM143ENSG00000161558.6245.35830314.71260-0.359102.038801.50540HepG2ETF1
TMEM143ENSG00000161558.6139.77160234.58330-0.747004.185803.15880HepG2EWSR1
TMEM143ENSG00000161558.6194.44550354.26560-0.865504.783603.79360HepG2FIP1L1
TMEM143ENSG00000161558.6201.40180138.644900.538602.081501.30830HepG2GEMIN5
TMEM143ENSG00000161558.6164.11940229.19750-0.481802.542701.60170HepG2HDGF
TMEM143ENSG00000161558.6170.62110246.51640-0.530902.622801.71080HepG2HNRNPA2B1
TMEM143ENSG00000161558.6250.84570167.126400.585802.556201.88790HepG2HNRNPC
TMEM143ENSG00000161558.6183.85880244.34090-0.410301.879001.30900HepG2HNRNPL
TMEM143ENSG00000161558.6167.16070244.41000-0.548102.555201.64040HepG2HNRNPM
TMEM143ENSG00000161558.6140.94940207.39640-0.557202.044601.45530HepG2IGF2BP2
TMEM143ENSG00000161558.6242.23960370.78920-0.614202.948202.09000HepG2LARP4
TMEM143ENSG00000161558.6117.90010286.69080-1.2819010.490809.02080HepG2MSI2
TMEM143ENSG00000161558.6136.04500189.37960-0.477201.907901.38800HepG2PCBP1
TMEM143ENSG00000161558.6203.67460148.078500.459801.961701.33260HepG2PPIL4
TMEM143ENSG00000161558.661.36760131.98210-1.104803.836602.90470HepG2PRPF8
TMEM143ENSG00000161558.6169.95310269.52960-0.665304.465603.75170HepG2PUM1
TMEM143ENSG00000161558.6196.74510269.33240-0.453102.053801.47050HepG2PUM2
TMEM143ENSG00000161558.648.57850186.42040-1.940209.897108.62020HepG2RAVER1
TMEM143ENSG00000161558.6243.34830362.40460-0.574603.749502.76760HepG2RBM15
TMEM143ENSG00000161558.686.80420263.03520-1.5994014.8090013.80370HepG2RBM22
TMEM143ENSG00000161558.6110.45850186.49070-0.755603.336502.24050HepG2RBM27
TMEM143ENSG00000161558.6313.15490214.460600.546103.129902.56140HepG2NELFE
TMEM143ENSG00000161558.6123.11080182.73680-0.569802.480501.82840HepG2RPLP0
TMEM143ENSG00000161558.639.07090130.54610-1.740406.725905.56000HepG2RRP9
TMEM143ENSG00000161558.6274.89810147.851100.894707.245606.27430HepG2SAFB2
TMEM143ENSG00000161558.6136.49480314.86140-1.205905.891704.88360HepG2SF3A3
TMEM143ENSG00000161558.6148.36790257.86900-0.797504.362603.49410HepG2SF3B1
TMEM143ENSG00000161558.6128.96950297.07740-1.2038011.9269011.08070HepG2SRFBP1
TMEM143ENSG00000161558.6183.57390250.69270-0.449602.082901.53040HepG2SRSF5
TMEM143ENSG00000161558.6113.23190170.37300-0.589402.449101.92260HepG2SRSF9
TMEM143ENSG00000161558.6516.33440257.914101.0013013.9298012.95670HepG2SSB
TMEM143ENSG00000161558.6173.88070253.91710-0.546302.387001.70630HepG2TARDBP
TMEM143ENSG00000161558.669.72460114.21540-0.712002.285501.37280HepG2TFIP11
TMEM143ENSG00000161558.6222.18130161.330100.461602.018901.57770HepG2TIAL1
TMEM143ENSG00000161558.6217.70730162.762600.419501.932901.44510HepG2TRIM56
TMEM143ENSG00000161558.696.97770303.03490-1.6438015.0365013.52390HepG2U2AF1
TMEM143ENSG00000161558.6113.84370269.59090-1.243706.120005.28750HepG2UTP3
TMEM143ENSG00000161558.6270.42670167.774700.688602.220201.56510HepG2XRN2
TMEM143ENSG00000161558.6164.34710307.10470-0.902004.166603.53270HepG2ZNF622
TMEM143ENSG00000161558.6237.07730367.61910-0.632903.529502.11030K562APOBEC3C
TMEM143ENSG00000161558.6116.57510256.74730-1.139107.028106.16290K562AQR
TMEM143ENSG00000161558.6120.88800203.63950-0.752303.370301.30780K562YBX3
TMEM143ENSG00000161558.6283.62600512.34180-0.853108.708307.01840K562CELF1
TMEM143ENSG00000161558.6107.47730336.47950-1.6465021.5244019.87150K562DDX47
TMEM143ENSG00000161558.652.06570104.53680-1.005603.402502.38600K562EFTUD2
TMEM143ENSG00000161558.6149.87030212.89820-0.506402.436301.31500K562EIF2S1
TMEM143ENSG00000161558.683.79410189.64870-1.178404.052702.80850K562EIF3A
TMEM143ENSG00000161558.6307.27870416.63200-0.439202.921201.95690K562EIF4G2
TMEM143ENSG00000161558.679.22630210.59140-1.4104010.780409.67130K562FXR1
TMEM143ENSG00000161558.6195.06120304.10020-0.640603.919302.63230K562HNRNPL
TMEM143ENSG00000161558.6131.97960242.65790-0.878605.946504.62670K562HNRNPU
TMEM143ENSG00000161558.6223.91920145.897600.617902.450501.34860K562IGF2BP3
TMEM143ENSG00000161558.6245.61060444.07820-0.854407.176705.39620K562MSI2
TMEM143ENSG00000161558.664.93720134.03160-1.045504.055602.86510K562PCBP2
TMEM143ENSG00000161558.6277.15730428.10570-0.627305.136203.26110K562PNPT1
TMEM143ENSG00000161558.644.50420101.72710-1.192703.861002.97620K562PRPF8
TMEM143ENSG00000161558.6289.88760179.209300.693703.851302.75940K562PSIP1
TMEM143ENSG00000161558.695.69300146.39380-0.613401.896301.32760K562PTBP1
TMEM143ENSG00000161558.6180.25610454.56890-1.3345013.7243011.89760K562PUF60
TMEM143ENSG00000161558.6281.36240483.56260-0.781307.347105.54490K562PUM1
TMEM143ENSG00000161558.689.94670140.29770-0.641302.337901.57010K562RBM22
TMEM143ENSG00000161558.634.82500103.59960-1.572805.992304.78530K562RPS19
TMEM143ENSG00000161558.6177.16630303.73680-0.777705.611304.48020K562SF3A3
TMEM143ENSG00000161558.658.74410103.95580-0.823502.850601.98290K562SF3B4
TMEM143ENSG00000161558.6179.85440300.92350-0.742602.480401.34410K562SNRNP200
TMEM143ENSG00000161558.651.65570143.53050-1.474406.376105.31410K562SRSF1
TMEM143ENSG00000161558.6204.75770135.592700.594502.611401.59680K562SRSF5
TMEM143ENSG00000161558.635.2627096.91510-1.458605.215903.61730K562U2AF1
TMEM143ENSG00000161558.633.26290100.07820-1.589106.866105.60890K562U2AF2
TMEM143ENSG00000161558.6391.13960512.56410-0.390002.710901.32410K562UBE2L3
TMEM143ENSG00000161558.6248.26340326.40380-0.394802.256201.60310K562UPF1
TMEM143ENSG00000161558.6213.37840355.73280-0.737404.404102.88140K562UTP3
TMEM143ENSG00000161558.6181.48350290.42330-0.678305.057903.94380K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM143 is not available on ENCORE database.





6 RBPs can affect the splicing of TMEM143 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM143ENSG00000161558.6chr19-4886332848863433488485254884861148866547488667880.403000.000260.02776includedHepG2QKI
SETMEM143ENSG00000161558.6chr19-4886332848863433488485254884861148866547488667880.363000.000610.09279includedK562GPKOW
SETMEM143ENSG00000161558.6chr19-488633284886343348848525488486114886654748866788-0.332000.000710.05155excludedHepG2HNRNPL
MXETMEM143ENSG00000161558.6chr19-48848416488486114886332848863433488465774884670848866547488667880.417000.001360.097821includedHepG2FUBP3
MXETMEM143ENSG00000161558.6chr19-48848416488486114886654748866788488465774884670848867154488671950.562000.001480.056621includedHepG2BCCIP
MXETMEM143ENSG00000161558.6chr19-4884841648848611488633284886343348846577488467084886654748866788-0.481000.000430.019222includedHepG2RBFOX2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM143 is not avaliable on ENCORE database.