SMG5

General Information

Gene Name : SMG5
Gene ID : ENSG00000198952.8
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SMG5)

Not Available

Antibody Validation

Bethyl Labs: A302-804A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SMG5	ENSG00000198952.8	17.54	31.13	24.34	ENCSR000AEF
HepG2	SMG5	ENSG00000198952.8	53.90	42.44	48.17	ENCSR985KAT
K562	SMG5	ENSG00000198952.8	50.11	46.91	48.51	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	SMG5-BGKcLV33-K562		SMG5	K562	Released			CRISPR	KD% = no band on the position,
knockdown followed by RNA-seq	SMG5-BGKcLV33-K562	ENCSR183WOW	SMG5	K562	Released		ENCSR271ZAB	CRISPR	KD% = no band on the position,

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SMG5	ENCAB166GHC	A302-804A	1					BGKcLV33-55, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
SMG5	K562	CRISPR			BGKcLV33-51,BGKcLV33-52	BGKcLV33-1,BGKcLV33-2	no band on the position,	Released	ENCODE4
SMG5	K562	CRISPR	ENCSR183WOW	ENCSR271ZAB	SMG5-BGKcLV33-55,SMG5-BGKcLV33-56	NT-BGKcLV33-1,NT-BGKcLV33-2	no band on the position,	Released	ENCODE4
SMG5	HepG2	CRISPR			BGHcLV31-51,BGHcLV31-52	BGHcLV31-1,BGHcLV31-2	0.0,0.0	NotSatisfied	ENCODE4
SMG5	HepG2	CRISPR			BGHcLV34-51,BGHcLV34-52	BGHcLV34-1,BGHcLV34-2	0.0,0.0	NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
SMG5	Product_ID: A302-804A Lot_ID: 1 Source: Bethyl Labs Target Name: SMG5-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SMG5 is not avaliable on ENCORE database.

Proteins bound to RNA

SMG5 RNA is bound by 37 proteins.

eCLIP assay for SMG5 is not avaliable on ENCORE database.

37 proteins are bound to SMG5 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	156219610	156219712	-	3'-UTR,CDS,intron-Distal	4.01505	17.39480	HepG2	UPF1
chr1	156220092	156220157	-	3'-UTR,intron-Distal	4.19238	8.81165	K562	AKAP1
chr1	156219520	156219598	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.40309	27.40392	K562	UPF1
chr1	156219814	156219861	-	3'-UTR,intron-Distal,intron-Proximal	3.75217	13.33286	K562	UPF1
chr1	156220276	156220377	-	3'-UTR,intron-Distal	3.70824	17.67712	HepG2	UPF1
chr1	156219249	156219310	-	3'-UTR,intron-Distal	5.69983	12.73103	HepG2	UPF1
chr1	156220116	156220146	-	3'-UTR,intron-Distal	4.17648	5.05122	K562	DDX24
chr1	156219276	156219350	-	3'-UTR,intron-Distal	4.05410	11.76398	HepG2	AKAP1
chr1	156219627	156219717	-	3'-UTR,CDS,intron-Distal	3.29592	11.58501	HepG2	LSM11
chr1	156219509	156219572	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.27315	6.78262	HepG2	LSM11
chr1	156219721	156219778	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.40623	11.32637	HepG2	AKAP1
chr1	156220088	156220201	-	3'-UTR,intron-Distal	3.70717	30.33726	HepG2	UPF1
chr1	156219652	156219721	-	3'-UTR,CDS,intron-Distal	3.98282	6.15627	HepG2	PABPN1
chr1	156219168	156219210	-	3'-UTR,intron-Distal	3.61334	7.68538	HepG2	AKAP1
chr1	156219656	156219721	-	3'-UTR,CDS,intron-Distal	4.17937	11.81153	HepG2	AKAP1
chr1	156219237	156219276	-	3'-UTR,intron-Distal	3.89323	6.88718	HepG2	AKAP1
chr1	156219123	156219234	-	3'-UTR,intron-Distal	3.24572	6.88236	K562	DDX55
chr1	156220173	156220267	-	3'-UTR,intron-Distal	4.05950	14.29764	HepG2	AKAP1
chr1	156219071	156219232	-	3'-UTR,intron-Distal	5.82852	37.46656	K562	UPF1
chr1	156219236	156219360	-	3'-UTR,intron-Distal	3.77590	12.17397	HepG2	PABPN1
chr1	156219926	156220045	-	3'-UTR,intron-Distal	5.71014	35.04290	K562	UPF1
chr1	156219817	156219906	-	3'-UTR,intron-Distal,intron-Proximal	4.96454	10.85668	K562	AKAP1
chr1	156219198	156219272	-	3'-UTR,intron-Distal	4.67143	5.68358	K562	LSM11
chr1	156219124	156219201	-	3'-UTR,intron-Distal	4.63930	3.30609	K562	PCBP1
chr1	156219235	156219390	-	3'-UTR,intron-Distal	5.89628	39.24249	K562	UPF1
chr1	156219179	156219236	-	3'-UTR,intron-Distal	5.27530	8.61254	HepG2	PABPN1
chr1	156219144	156219231	-	3'-UTR,intron-Distal	4.47418	17.00065	HepG2	LSM11
chr1	156220089	156220173	-	3'-UTR,intron-Distal	4.50679	21.82906	HepG2	AKAP1
chr1	156219726	156219777	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.80272	13.82898	HepG2	UPF1
chr1	156220108	156220212	-	3'-UTR,intron-Distal	3.33159	5.82446	K562	AKAP8L
chr1	156219656	156219720	-	3'-UTR,CDS,intron-Distal	4.18342	7.63327	K562	AKAP1
chr1	156220280	156220383	-	3'-UTR,CDS,intron-Distal	4.93055	19.29184	HepG2	AKAP1
chr1	156219810	156219867	-	3'-UTR,intron-Distal,intron-Proximal	4.00208	10.65096	HepG2	UPF1
chr1	156219610	156219668	-	3'-UTR,CDS,intron-Distal	4.15356	18.04441	K562	UPF1
chr1	156219668	156219765	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.58824	31.97885	K562	UPF1
chr1	156219870	156219985	-	3'-UTR,intron-Distal	3.99086	14.82397	HepG2	AKAP1
chr1	156219182	156219249	-	3'-UTR,intron-Distal	4.85182	13.34636	HepG2	UPF1
chr1	156219806	156219870	-	3'-UTR,intron-Distal,intron-Proximal	3.51583	9.92771	HepG2	AKAP1
chr1	156220303	156220376	-	3'-UTR,intron-Distal	3.44645	6.23926	K562	AKAP1
chr1	156219231	156219284	-	3'-UTR,intron-Distal	3.95479	9.09695	HepG2	LSM11
chr1	156219175	156219334	-	3'-UTR,intron-Distal	3.40168	6.45817	K562	NOLC1
chr1	156219098	156219173	-	3'-UTR,intron-Distal	4.49830	3.07376	K562	PABPC4
chr1	156219815	156219836	-	3'-UTR,intron-Distal,intron-Proximal	3.37806	3.57490	HepG2	NKRF
chr1	156220201	156220273	-	3'-UTR,intron-Distal	4.10102	15.63151	HepG2	UPF1
chr1	156220076	156220234	-	3'-UTR,intron-Distal	4.40723	33.74352	K562	UPF1
chr1	156252467	156252524	-	5'-UTR,CDS,intron-Distal	3.68647	8.48758	HepG2	EIF3H
chr1	156252466	156252512	-	5'-UTR,CDS,intron-Distal	4.87872	7.39978	HepG2	UPF1
chr1	156252533	156252594	-	5'-UTR,intron-Distal	4.17183	7.48534	K562	LIN28B
chr1	156220760	156220818	-	CDS,intron-Distal,intron-Proximal	3.48841	5.33180	HepG2	U2AF1
chr1	156237905	156237944	-	CDS,intron-Distal,intron-Proximal	3.86116	16.89106	HepG2	BCLAF1
chr1	156233323	156233381	-	CDS,intron-Distal,intron-Proximal	4.05347	4.71391	K562	U2AF2
chr1	156235881	156235898	-	CDS,intron-Distal,intron-Proximal	3.58102	3.49265	HepG2	EIF3H
chr1	156246872	156246907	-	CDS,intron-Distal,intron-Proximal	5.22784	5.68502	HepG2	PRPF8
chr1	156220647	156220702	-	CDS,intron-Distal,intron-Proximal	3.19832	7.95442	HepG2	GRWD1
chr1	156238090	156238119	-	CDS,intron-Distal	4.30841	8.74054	HepG2	PPIG
chr1	156246881	156246930	-	CDS,intron-Distal	3.84767	6.23335	HepG2	GRWD1
chr1	156238154	156238199	-	CDS,intron-Distal	3.81936	11.19453	HepG2	BCLAF1
chr1	156233113	156233193	-	CDS,intron-Distal,intron-Proximal	4.24759	5.63763	K562	AQR
chr1	156238081	156238143	-	CDS,intron-Distal	6.34408	18.15906	HepG2	BCLAF1
chr1	156237265	156237288	-	CDS,intron-Distal	3.41270	5.58370	HepG2	PPIG
chr1	156237444	156237469	-	CDS,intron-Distal,intron-Proximal	3.68535	15.25871	HepG2	BCLAF1
chr1	156236129	156236149	-	CDS,intron-Distal	4.00395	3.80193	HepG2	GRWD1
chr1	156236058	156236104	-	CDS,intron-Distal	3.96251	8.05048	HepG2	EIF3H
chr1	156246893	156246919	-	CDS,intron-Distal	3.35684	7.36645	HepG2	PPIG
chr1	156221163	156221243	-	CDS,intron-Distal,intron-Proximal	3.05283	5.87166	HepG2	GRWD1
chr1	156237905	156237924	-	CDS,intron-Distal,intron-Proximal	5.59316	7.72885	K562	DDX24
chr1	156248765	156248831	-	CDS,intron-Distal,intron-Proximal	3.44095	6.64170	K562	BUD13
chr1	156235906	156235978	-	CDS,intron-Distal,intron-Proximal	4.91169	5.61356	K562	FMR1
chr1	156244438	156244472	-	CDS,intron-Distal	3.16309	8.98767	HepG2	PPIG
chr1	156235800	156235848	-	CDS,intron-Distal,intron-Proximal	3.30543	9.44064	HepG2	PPIG
chr1	156236140	156236216	-	CDS,intron-Distal,intron-Proximal	3.66346	8.07862	HepG2	SF3B4
chr1	156228798	156228876	-	CDS,intron-Distal	3.32815	4.82446	HepG2	YBX3
chr1	156228808	156228845	-	CDS,intron-Distal	3.91270	9.27186	HepG2	PPIG
chr1	156243212	156243241	-	CDS,intron-Distal	3.84659	8.81620	HepG2	BCLAF1
chr1	156242111	156242125	-	CDS,intron-Distal	3.48033	6.74947	HepG2	BCLAF1
chr1	156220656	156220692	-	CDS,intron-Distal	3.80969	9.28206	HepG2	PPIG
chr1	156228812	156228858	-	CDS,intron-Distal	3.37279	3.40321	HepG2	GRWD1
chr1	156252359	156252422	-	CDS,intron-Distal	5.98557	11.80896	HepG2	PRPF8
chr1	156220781	156220863	-	CDS,intron-Distal,intron-Proximal	4.95845	32.01008	HepG2	SF3A3
chr1	156221129	156221214	-	CDS,intron-Distal,intron-Proximal	3.80166	16.25866	HepG2	PRPF8
chr1	156221095	156221198	-	CDS,intron-Distal,intron-Proximal	3.76088	6.14054	K562	PRPF8
chr1	156221207	156221221	-	CDS,intron-Distal,intron-Proximal	3.28645	4.14964	K562	UPF1
chr1	156228945	156229024	-	CDS,intron-Distal,intron-Proximal	4.54875	5.25202	HepG2	AQR
chr1	156236120	156236165	-	CDS,intron-Distal	3.49972	9.51790	HepG2	PPIG
chr1	156244413	156244456	-	CDS,intron-Distal	3.76691	3.01533	HepG2	SRSF1
chr1	156236025	156236080	-	CDS,intron-Distal	3.01349	5.28660	HepG2	HLTF
chr1	156222828	156222884	-	CDS,intron-Distal,intron-Proximal	4.93262	4.48002	K562	AQR
chr1	156221202	156221261	-	CDS,intron-Distal,intron-Proximal	3.78522	5.57819	K562	UCHL5
chr1	156244390	156244410	-	CDS,intron-Distal	3.69475	8.50755	HepG2	BCLAF1
chr1	156236332	156236359	-	CDS,intron-Distal	5.13876	5.75302	HepG2	EIF3H
chr1	156228801	156228857	-	CDS,intron-Distal	4.03723	5.63221	K562	METAP2
chr1	156243151	156243184	-	CDS,intron-Distal,intron-Proximal	3.77447	12.86652	K562	YBX3
chr1	156237441	156237469	-	CDS,intron-Distal,intron-Proximal	5.40021	5.73530	K562	DDX24
chr1	156222209	156222294	-	CDS,intron-Distal	3.87942	18.83301	HepG2	PPIG
chr1	156220702	156220751	-	CDS,intron-Distal	3.19883	5.59833	HepG2	GRWD1
chr1	156228815	156228855	-	CDS,intron-Distal	3.39877	3.92010	K562	DDX55
chr1	156233331	156233378	-	CDS,intron-Distal,intron-Proximal	3.23168	3.83577	HepG2	U2AF2
chr1	156231123	156231170	-	CDS,intron-Distal,intron-Proximal	4.06664	17.98460	HepG2	PPIG
chr1	156221196	156221265	-	CDS,intron-Distal,intron-Proximal	3.76457	16.24592	HepG2	PPIG
chr1	156247759	156247800	-	CDS,intron-Distal	5.09784	14.71257	HepG2	BCLAF1
chr1	156244411	156244481	-	CDS,intron-Distal,intron-Proximal	3.33520	5.07297	K562	BUD13
chr1	156251084	156251140	-	intron-Distal	3.41964	3.90822	HepG2	HNRNPM
chr1	156220794	156220846	-	intron-Distal,intron-Proximal	4.46597	6.59856	K562	SF3B4
chr1	156250968	156251035	-	intron-Distal	4.78813	6.44072	HepG2	HNRNPM
chr1	156222969	156223055	-	intron-Distal	3.68556	3.30744	K562	PTBP1
chr1	156252024	156252130	-	intron-Distal	3.00371	3.62838	HepG2	FAM120A
chr1	156244311	156244357	-	intron-Distal,intron-Proximal	4.28808	5.67291	HepG2	U2AF2
chr1	156251948	156252136	-	intron-Distal	4.10172	4.60998	HepG2	PCBP2
chr1	156241953	156242042	-	intron-Distal,intron-Proximal	4.70134	10.67832	HepG2	U2AF2
chr1	156247595	156247660	-	intron-Distal,intron-Proximal	4.53781	5.32062	K562	EFTUD2
chr1	156220838	156220940	-	intron-Distal,intron-Proximal	3.42723	8.32850	HepG2	HNRNPK
chr1	156221147	156221190	-	intron-Distal,intron-Proximal	3.03892	8.85468	HepG2	BCLAF1
chr1	156222346	156222402	-	intron-Distal,intron-Proximal	4.91942	5.90023	K562	SF3B4
chr1	156246830	156246859	-	intron-Distal,intron-Proximal	4.07368	3.31283	K562	PRPF8
chr1	156221152	156221170	-	intron-Distal,intron-Proximal	4.34851	6.54243	HepG2	BUD13
chr1	156252167	156252217	-	intron-Distal	4.31013	3.48173	K562	GTF2F1
chr1	156244311	156244358	-	intron-Distal,intron-Proximal	3.52845	6.04627	K562	U2AF2
chr1	156238208	156238252	-	intron-Distal,intron-Proximal	5.12694	5.90023	K562	SF3B4
chr1	156248682	156248700	-	intron-Distal,intron-Proximal	4.93262	6.04760	K562	AQR
chr1	156252217	156252290	-	intron-Distal	4.82920	5.24810	K562	GTF2F1
chr1	156252039	156252121	-	intron-Distal	3.59419	5.61462	HepG2	PRPF4
chr1	156246798	156246876	-	intron-Distal,intron-Proximal	5.46454	8.03507	K562	AQR
chr1	156241981	156242037	-	intron-Distal,intron-Proximal	3.37839	3.88924	K562	PRPF8
chr1	156252234	156252290	-	intron-Distal	4.50371	3.99130	HepG2	FAM120A
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for SMG5 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SMG5 is not available on ENCORE database.
75 RBPs can affect the levels of SMG5.

The Knockdown/knockout RNA-Seq assay for SMG5 is not available on ENCORE database.

75 RBPs can affect the gene expression of SMG5 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SMG5	ENSG00000198952.7	2222.81680	3015.43720	-0.44000	10.59310	9.56380	HepG2	ACO1
SMG5	ENSG00000198952.7	2622.79820	3029.38690	-0.20790	2.51420	1.77910	HepG2	AKAP8L
SMG5	ENSG00000198952.7	3488.06430	4400.95460	-0.33540	6.09680	5.14050	HepG2	AUH
SMG5	ENSG00000198952.7	1898.05760	2314.93440	-0.28640	2.72470	1.50290	HepG2	BUD13
SMG5	ENSG00000198952.7	1423.69220	1834.49850	-0.36570	3.80820	2.92430	HepG2	CALR
SMG5	ENSG00000198952.7	3452.21870	2829.68580	0.28680	2.08910	1.41080	HepG2	CIRBP
SMG5	ENSG00000198952.7	1142.97170	1510.65560	-0.40240	3.51370	2.74800	HepG2	CPSF6
SMG5	ENSG00000198952.7	3735.33710	3008.45140	0.31210	3.83720	3.10220	HepG2	CELF1
SMG5	ENSG00000198952.7	3801.62180	3234.39660	0.23300	3.56700	2.74480	HepG2	DAZAP1
SMG5	ENSG00000198952.7	1668.32280	2127.00560	-0.35040	3.25220	2.51990	HepG2	DDX21
SMG5	ENSG00000198952.7	1534.21480	2081.62060	-0.44020	5.37640	4.09660	HepG2	DDX24
SMG5	ENSG00000198952.7	2665.31140	3448.03900	-0.37150	2.99260	2.34520	HepG2	DDX3X
SMG5	ENSG00000198952.7	2280.33760	1916.83200	0.25040	3.90790	3.16040	HepG2	DNAJC2
SMG5	ENSG00000198952.7	1439.20550	1958.81410	-0.44470	3.03290	1.86710	HepG2	AGO1
SMG5	ENSG00000198952.7	2282.36760	3120.31120	-0.45120	3.70410	2.82160	HepG2	FIP1L1
SMG5	ENSG00000198952.7	3796.48210	2963.69310	0.35720	6.58070	5.53860	HepG2	HNRNPF
SMG5	ENSG00000198952.7	3628.89080	2983.24750	0.28250	2.25800	1.62270	HepG2	HNRNPK
SMG5	ENSG00000198952.7	3576.17880	2946.15810	0.27950	6.33330	5.35330	HepG2	HNRNPL
SMG5	ENSG00000198952.7	2518.54100	2157.42480	0.22320	2.85880	2.24310	HepG2	HNRNPU
SMG5	ENSG00000198952.7	3954.90550	2918.38810	0.43840	6.50580	5.43770	HepG2	IGF2BP1
SMG5	ENSG00000198952.7	1898.83790	2659.77640	-0.48620	3.58040	2.63450	HepG2	LARP4
SMG5	ENSG00000198952.7	2038.08250	2524.97630	-0.30910	3.10680	2.25180	HepG2	MSI2
SMG5	ENSG00000198952.7	2245.34790	2911.03760	-0.37460	2.95370	2.21020	HepG2	PABPC4
SMG5	ENSG00000198952.7	1850.79800	2135.51120	-0.20640	2.19090	1.42880	HepG2	PARN
SMG5	ENSG00000198952.7	1384.20780	1750.56330	-0.33880	2.58310	1.80180	HepG2	PRPF8
SMG5	ENSG00000198952.7	2257.39910	3061.71340	-0.43970	5.16180	4.37910	HepG2	PUF60
SMG5	ENSG00000198952.7	3733.16280	3071.38010	0.28140	5.11640	4.32530	HepG2	PUS1
SMG5	ENSG00000198952.7	3639.07500	4223.28140	-0.21480	2.34210	1.85500	HepG2	RBM22
SMG5	ENSG00000198952.7	2073.60890	2584.63460	-0.31780	2.88370	1.87090	HepG2	RBM27
SMG5	ENSG00000198952.7	4359.37090	3192.67620	0.44930	5.42980	4.51790	HepG2	RPLP0
SMG5	ENSG00000198952.7	1422.12950	1678.23830	-0.23890	1.83930	1.32810	HepG2	RPS19
SMG5	ENSG00000198952.7	2652.94970	3134.05080	-0.24040	3.37230	2.72810	HepG2	SF3B4
SMG5	ENSG00000198952.7	2663.86920	2040.86110	0.38420	2.17180	1.33440	HepG2	SMNDC1
SMG5	ENSG00000198952.7	763.23120	1799.64810	-1.23750	13.88840	12.16060	HepG2	SNRNP70
SMG5	ENSG00000198952.7	3863.13860	2911.74270	0.40780	8.40170	7.30280	HepG2	SRSF7
SMG5	ENSG00000198952.7	1485.95530	2083.79490	-0.48780	3.26160	1.92320	HepG2	STAU1
SMG5	ENSG00000198952.7	3775.76960	3438.02590	0.13510	1.90510	1.37110	HepG2	SUCLG1
SMG5	ENSG00000198952.7	2324.35430	2940.16910	-0.33910	4.86310	4.15270	HepG2	TAF15
SMG5	ENSG00000198952.7	1304.36380	1593.07090	-0.28850	2.07290	1.43300	HepG2	TARDBP
SMG5	ENSG00000198952.7	2278.00670	2701.75620	-0.24610	2.27800	1.51740	HepG2	TIA1
SMG5	ENSG00000198952.7	1849.15620	2668.99590	-0.52940	5.97140	5.06510	HepG2	U2AF1
SMG5	ENSG00000198952.7	2807.74050	2482.39570	0.17760	2.07870	1.54490	HepG2	UTP3
SMG5	ENSG00000198952.7	2497.19300	2827.83240	-0.17940	2.53510	2.00540	HepG2	ZNF622
SMG5	ENSG00000198952.7	3041.13650	4585.97550	-0.59260	9.13850	8.17260	K562	AQR
SMG5	ENSG00000198952.7	4364.20440	3406.82390	0.35720	6.86010	5.89840	K562	DDX47
SMG5	ENSG00000198952.7	3946.01740	3435.47900	0.19980	2.15550	1.39310	K562	DKC1
SMG5	ENSG00000198952.7	1508.20650	2018.48570	-0.42040	4.15130	2.47950	K562	DNAJC21
SMG5	ENSG00000198952.7	3698.47120	2579.11150	0.52000	4.03240	2.45630	K562	EEF2
SMG5	ENSG00000198952.7	3680.90010	2667.41810	0.46450	3.82430	2.58640	K562	EIF3D
SMG5	ENSG00000198952.7	2411.03970	1411.22400	0.77260	18.14680	16.04680	K562	EIF3G
SMG5	ENSG00000198952.7	3468.07300	2216.77200	0.64560	10.23740	8.64050	K562	EIF4A3
SMG5	ENSG00000198952.7	1207.09000	1509.77120	-0.32280	2.99700	1.33210	K562	FASTKD2
SMG5	ENSG00000198952.7	1565.27350	2014.21420	-0.36380	2.72320	1.60760	K562	FKBP4
SMG5	ENSG00000198952.7	1139.60820	1429.28850	-0.32680	2.09900	1.30920	K562	FTO
SMG5	ENSG00000198952.7	3313.73850	2305.34260	0.52340	11.42330	10.28040	K562	FXR1
SMG5	ENSG00000198952.7	621.96780	1306.81690	-1.07110	9.34490	7.88990	K562	G3BP2
SMG5	ENSG00000198952.7	3776.60780	2088.72580	0.85440	18.95130	16.58040	K562	MAGOH
SMG5	ENSG00000198952.7	4360.98590	5637.55400	-0.37040	3.97480	2.62360	K562	MSI2
SMG5	ENSG00000198952.7	3380.11380	2908.94320	0.21650	3.03290	2.18850	K562	MTPAP
SMG5	ENSG00000198952.7	2849.44520	4110.98240	-0.52880	5.61570	4.42520	K562	PCBP3
SMG5	ENSG00000198952.7	2414.61090	3153.21790	-0.38500	5.03380	3.95100	K562	POLR2G
SMG5	ENSG00000198952.7	2934.71690	2424.70300	0.27530	1.96130	1.32310	K562	PRPF8
SMG5	ENSG00000198952.7	3354.24520	2029.42920	0.72480	14.95550	13.47680	K562	PTBP1
SMG5	ENSG00000198952.7	5152.27800	6138.16400	-0.25260	2.75010	1.68780	K562	PUM1
SMG5	ENSG00000198952.7	5003.64800	6014.07320	-0.26540	3.83760	2.70290	K562	PUM2
SMG5	ENSG00000198952.7	4019.33690	3166.22970	0.34410	2.49330	1.97160	K562	PUS1
SMG5	ENSG00000198952.7	3164.83700	2469.53010	0.35780	2.51170	1.73520	K562	RPS19
SMG5	ENSG00000198952.7	2192.43830	1731.48120	0.34040	2.50000	1.55440	K562	RPS3
SMG5	ENSG00000198952.7	3468.23220	2809.73690	0.30370	3.01430	1.88480	K562	SAFB
SMG5	ENSG00000198952.7	2853.25620	1796.52100	0.66730	2.49170	1.37460	K562	SF1
SMG5	ENSG00000198952.7	3688.11020	3189.26260	0.20960	2.24270	1.50240	K562	SF3A3
SMG5	ENSG00000198952.7	1856.24310	1358.15620	0.45060	5.80400	4.53400	K562	SF3B4
SMG5	ENSG00000198952.7	3608.60380	2190.13700	0.72030	3.26370	1.80390	K562	SFPQ
SMG5	ENSG00000198952.7	4064.52330	3267.47040	0.31480	6.98420	5.57260	K562	SRPK2
SMG5	ENSG00000198952.7	2592.20710	1989.66920	0.38160	3.56960	2.77340	K562	SRSF1
SMG5	ENSG00000198952.7	2106.45160	3093.06150	-0.55420	4.19900	2.59650	K562	STAU1
SMG5	ENSG00000198952.7	4246.96720	3162.82300	0.42510	6.48790	5.22210	K562	SYNCRIP
SMG5	ENSG00000198952.7	2844.99940	2013.34750	0.49870	4.84970	3.89990	K562	TARDBP
SMG5	ENSG00000198952.7	1960.73770	2484.38210	-0.34150	2.85710	1.81900	K562	UCHL5
SMG5	ENSG00000198952.7	3668.18160	3049.38300	0.26640	4.81740	3.72860	K562	WDR43
SMG5	ENSG00000198952.7	3670.66590	2374.47270	0.62830	3.21300	1.48320	K562	XRCC6
SMG5	ENSG00000198952.7	3953.57430	5166.59260	-0.38610	4.50650	3.36210	K562	ZC3H8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SMG5 is not available on ENCORE database.

15 RBPs can affect the splicing of SMG5 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SMG5	ENSG00000198952.7	chr1	-	156242110	156242189			156238080	156238206	156243151	156243241	-0.06600	0.00170	0.03237	excluded	K562	SF3B4
SE	SMG5	ENSG00000198952.7	chr1	-	156244387	156244477			156243151	156243241	156246875	156247032	-0.07500	0.00112	0.02265	excluded	HepG2	U2AF1
SE	SMG5	ENSG00000198952.7	chr1	-	156243354	156243439			156243151	156243241	156244387	156244477	0.07600	0.00001	0.00306	included	K562	FMR1
SE	SMG5	ENSG00000198952.7	chr1	-	156243354	156243439			156243151	156243241	156244387	156244477	0.09600	0.00000	0.00000	included	HepG2	HNRNPK
SE	SMG5	ENSG00000198952.7	chr1	-	156242110	156242189			156238080	156238206	156243151	156243241	-0.05700	0.00364	0.07532	excluded	HepG2	HNRNPK
SE	SMG5	ENSG00000198952.7	chr1	-	156243354	156243439			156243151	156243241	156244387	156244477	0.05800	0.00025	0.05989	included	K562	METAP2
SE	SMG5	ENSG00000198952.7	chr1	-	156236297	156236507			156236075	156236171	156237260	156237469	0.39500	0.00406	0.03921	included	K562	AQR
SE	SMG5	ENSG00000198952.7	chr1	-	156251583	156251715			156248726	156248825	156252397	156252616	-0.05300	0.00150	0.09722	excluded	K562	SUPV3L1
SE	SMG5	ENSG00000198952.7	chr1	-	156221193	156221268			156220648	156220787	156222204	156222295	-0.13100	0.00000	0.00003	excluded	K562	SUPV3L1
SE	SMG5	ENSG00000198952.7	chr1	-	156243354	156243439			156243151	156243241	156244387	156244477	0.07500	0.00001	0.00490	included	K562	GPKOW
SE	SMG5	ENSG00000198952.7	chr1	-	156234104	156234234			156233185	156233361	156235571	156236171	0.12500	0.00146	0.02720	included	K562	U2AF2
SE	SMG5	ENSG00000198952.7	chr1	-	156234104	156234234			156233185	156233361	156235571	156236171	0.06500	0.00304	0.08657	included	K562	TARDBP
SE	SMG5	ENSG00000198952.7	chr1	-	156242110	156242215			156238080	156238206	156243151	156243241	-0.05600	0.00474	0.08763	excluded	K562	RBM15
SE	SMG5	ENSG00000198952.7	chr1	-	156243354	156243439			156243151	156243241	156244387	156244477	0.08700	0.00000	0.00097	included	K562	CPSF6
SE	SMG5	ENSG00000198952.7	chr1	-	156243354	156243439			156243151	156243241	156244387	156244477	0.06300	0.00015	0.00985	included	HepG2	HNRNPU
SE	SMG5	ENSG00000198952.7	chr1	-	156242110	156242189			156238080	156238206	156243151	156243241	-0.06400	0.00178	0.03080	excluded	K562	HNRNPC
A3SS	SMG5	ENSG00000198952.7	chr1	-	156247715	156247878			156247715	156247839	156248726	156248958	0.05200	0.00014	0.00119	longer	K562	AQR
A3SS	SMG5	ENSG00000198952.7	chr1	-	156248726	156248958			156248726	156248825	156252397	156252620	0.08100	0.00010	0.00090	longer	K562	AQR
A3SS	SMG5	ENSG00000198952.7	chr1	-	156242110	156242215			156242110	156242189	156243151	156243241	0.05200	0.00110	0.00756	longer	K562	AQR
A3SS	SMG5	ENSG00000198952.7	chr1	-	156246843	156247056			156246843	156247032	156247715	156247839	0.05600	0.00005	0.00047	longer	K562	AQR
A3SS	SMG5	ENSG00000198952.7	chr1	-	156231123	156231231			156231123	156231199	156233185	156233361	0.06100	0.00001	0.00010	longer	K562	AQR
A3SS	SMG5	ENSG00000198952.7	chr1	-	156223239	156223318			156223239	156223299	156228795	156228925	0.05700	0.00003	0.00031	longer	K562	AQR
MXE	SMG5	ENSG00000198952.7	chr1	-	156244387	156244477	156246875	156247056	156243151	156243241	156247715	156247839	0.07000	0.00124	0.02505	1included	HepG2	U2AF1
MXE	SMG5	ENSG00000198952.7	chr1	-	156242110	156242189	156243151	156243241	156238080	156238206	156244387	156244477	-0.10700	0.00027	0.03286	2included	K562	ZNF800

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SMG5

General Information

Functions

Localization

Domains (AlphaFold: SMG5)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SMG5 is not avaliable on ENCORE database.

37 proteins are bound to SMG5 RNA:

eCLIP assay for SMG5 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SMG5 is not available on ENCORE database.

75 RBPs can affect the gene expression of SMG5 :

The Knockdown/knockout RNA-Seq assay for SMG5 is not available on ENCORE database.

15 RBPs can affect the splicing of SMG5 :

The Knockdown/knockout RNA-Seq assay for SMG5 is not avaliable on ENCORE database.