PARL

General Information

Gene Name       : PARL
Gene ID             : ENSG00000175193.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PARL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PARLENSG00000175193.1344.6139.8542.23ENCSR000AEF
HepG2PARLENSG00000175193.1330.0444.8137.42ENCSR985KAT
K562PARLENSG00000175193.1347.3037.0142.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PARL is not avaliable on ENCORE database.



Proteins bound to RNA
  • PARL RNA is bound by 7 proteins.  







eCLIP assay for PARL is not avaliable on ENCORE database.





7 proteins are bound to PARL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3183602515183602678-5'-UTR,CDS,intron-Distal,intron-Proximal4.1511511.04568HepG2NCBP2
chr3183602531183602679-5'-UTR,CDS,intron-Distal,intron-Proximal3.035463.62869K562NCBP2
chr3183602579183602660-5'-UTR,CDS,intron-Distal,intron-Proximal4.896474.14061K562DROSHA
chr3183584416183584476-CDS,intron-Distal3.969145.79432HepG2BCLAF1
chr3183585754183585812-CDS,intron-Distal3.274864.74886HepG2BCLAF1
chr3183567033183567087-intron-Distal4.353995.31529HepG2SUGP2
chr3183601930183602101-intron-Distal4.465673.28572K562HNRNPM
chr3183568664183568717-intron-Distal3.965753.29248HepG2SUGP2
chr3183567886183567916-intron-Distal3.761063.04224HepG2SUGP2
chr3183564373183564513-intron-Distal4.113526.06017HepG2QKI
chr3183572883183572999-intron-Distal3.199813.23948HepG2HNRNPK
chr3183569021183569061-intron-Distal3.804793.29248HepG2SUGP2
chr3183601401183601488-intron-Distal5.346977.94700HepG2QKI
chr3183562650183562758-intron-Distal,intron-Proximal4.221023.83958HepG2QKI
chr3183601989183602108-intron-Distal4.737194.66899HepG2HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PARL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PARL is not available on ENCORE database.

  • 66 RBPs can affect the levels of PARL.  








The Knockdown/knockout RNA-Seq assay for PARL is not available on ENCORE database.





66 RBPs can affect the gene expression of PARL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PARLENSG00000175193.8431.529701003.48740-1.2175014.9212013.78620HepG2AKAP1
PARLENSG00000175193.8402.88420534.88150-0.408903.251902.42720HepG2AKAP8L
PARLENSG00000175193.8264.27960553.72820-1.067108.917607.17410HepG2CCAR1
PARLENSG00000175193.8638.98010532.272500.263501.990601.41470HepG2CKAP4
PARLENSG00000175193.8280.92990419.26490-0.577702.430201.71640HepG2CNOT7
PARLENSG00000175193.8290.85680422.57050-0.538903.170702.43950HepG2CPSF6
PARLENSG00000175193.8482.65550825.66300-0.774606.582905.66120HepG2DDX6
PARLENSG00000175193.8549.62910793.86040-0.530403.744903.06180HepG2EIF2S1
PARLENSG00000175193.8578.45250854.12440-0.562203.250202.50730HepG2EIF4B
PARLENSG00000175193.81098.33310746.044200.557908.299706.99450HepG2EIF4G1
PARLENSG00000175193.8895.595601049.96610-0.229401.893401.37610HepG2ETF1
PARLENSG00000175193.8394.45400514.81220-0.384202.280001.56050HepG2FUBP3
PARLENSG00000175193.8675.42220885.04070-0.390002.415701.76730HepG2FXR1
PARLENSG00000175193.8490.27930821.10550-0.744006.647405.63720HepG2G3BP1
PARLENSG00000175193.8388.76290525.30960-0.434302.229601.31990HepG2GNB2L1
PARLENSG00000175193.8230.96320479.02630-1.052408.893207.78850HepG2GPKOW
PARLENSG00000175193.8347.56040457.14280-0.395401.900701.37000HepG2HNRNPLL
PARLENSG00000175193.8433.86580783.15920-0.852103.405902.31360HepG2IGF2BP3
PARLENSG00000175193.8352.67940435.82020-0.305402.129201.47630HepG2ILF2
PARLENSG00000175193.8662.82340890.33510-0.425702.487901.88630HepG2MATR3
PARLENSG00000175193.8697.13730911.33270-0.386502.284401.70690HepG2NCBP2
PARLENSG00000175193.8612.63670811.71730-0.405902.450001.76700HepG2PABPC4
PARLENSG00000175193.8694.64930864.07590-0.314902.897302.34000HepG2PTBP1
PARLENSG00000175193.8464.63940759.85090-0.7096011.7373010.69390HepG2PUM1
PARLENSG00000175193.81155.18380877.576600.396404.390103.77690HepG2RBM22
PARLENSG00000175193.8660.34100961.63270-0.542307.045306.25090HepG2NELFE
PARLENSG00000175193.8675.37030895.63170-0.407204.280103.53580HepG2RECQL
PARLENSG00000175193.8387.33350572.32860-0.563303.888302.94540HepG2RPS2
PARLENSG00000175193.8513.94330379.952500.435703.720702.99290HepG2SAFB2
PARLENSG00000175193.8659.41310452.486600.543204.027903.19180HepG2SF3B1
PARLENSG00000175193.8219.99270489.14350-1.152803.262001.66920HepG2SFPQ
PARLENSG00000175193.8231.08050503.46870-1.123507.875206.55360HepG2SNRNP70
PARLENSG00000175193.8853.19000991.18900-0.216301.738401.31270HepG2SRFBP1
PARLENSG00000175193.8658.21570939.00170-0.512606.529505.87740HepG2SRSF1
PARLENSG00000175193.8342.98530486.86120-0.505402.414601.48650HepG2SRSF3
PARLENSG00000175193.8464.64080706.74710-0.605107.340206.38770HepG2SRSF5
PARLENSG00000175193.8542.48140763.92850-0.493905.933105.18090HepG2SRSF9
PARLENSG00000175193.8260.75890436.02960-0.741704.095603.29680HepG2SUPV3L1
PARLENSG00000175193.8769.42280462.787900.733306.310905.37870HepG2U2AF1
PARLENSG00000175193.8635.09740527.158500.268602.094001.59950HepG2ZNF622
PARLENSG00000175193.81059.43220762.162300.475006.075005.28540K562AGGF1
PARLENSG00000175193.81078.99230837.469500.365502.802101.81100K562AKAP8
PARLENSG00000175193.8999.27970793.056700.333402.328801.72820K562AKAP8L
PARLENSG00000175193.8745.525601235.94330-0.729308.500607.56300K562AQR
PARLENSG00000175193.8340.52170485.08480-0.510502.389801.58520K562BOP1
PARLENSG00000175193.8179.54890284.98120-0.666503.880602.58770K562CCAR1
PARLENSG00000175193.8370.24860515.80750-0.478302.359601.62950K562CPSF6
PARLENSG00000175193.8369.43800506.94200-0.456503.084101.96270K562CSTF2
PARLENSG00000175193.81083.07710865.476700.323503.376602.66710K562DDX47
PARLENSG00000175193.81132.57340853.434600.408204.587403.41790K562DKC1
PARLENSG00000175193.8637.54690835.16240-0.389503.691502.88200K562EIF2S2
PARLENSG00000175193.81066.326401272.88230-0.255402.559901.65190K562EIF4G2
PARLENSG00000175193.8340.37000524.77700-0.624603.832802.81980K562FMR1
PARLENSG00000175193.8309.85010444.77630-0.521502.806801.88600K562FTO
PARLENSG00000175193.8288.69610492.48780-0.770506.139604.95880K562GPKOW
PARLENSG00000175193.8326.33110500.49040-0.617004.578203.82830K562HNRNPC
PARLENSG00000175193.8928.82130549.246300.757807.411005.77170K562HNRNPM
PARLENSG00000175193.8284.84060420.47450-0.561902.694501.77660K562KRR1
PARLENSG00000175193.81080.92560834.681400.372903.194702.28830K562MAGOH
PARLENSG00000175193.81233.05880942.866400.387003.705102.62730K562MBNL1
PARLENSG00000175193.8894.68000660.878700.436902.342101.54670K562NAA15
PARLENSG00000175193.8948.16680742.619900.352402.509601.57960K562PCBP2
PARLENSG00000175193.8717.39800520.098000.463903.163802.36170K562PRPF8
PARLENSG00000175193.81248.201201477.40680-0.243202.324001.35340K562PUM1
PARLENSG00000175193.81153.006501447.33950-0.328003.770502.64690K562PUM2
PARLENSG00000175193.81171.42140786.550400.574505.485804.75300K562PUS1
PARLENSG00000175193.8988.07880766.328600.366603.313202.67350K562RBM15
PARLENSG00000175193.8532.88560728.06560-0.450204.066303.08780K562SF3A3
PARLENSG00000175193.8554.92820428.445100.373102.231001.49250K562SYNCRIP
PARLENSG00000175193.8825.61750575.345000.520902.950801.81640K562U2AF1
PARLENSG00000175193.8570.03320782.26390-0.456604.866703.94320K562UPF1
PARLENSG00000175193.8507.02450669.35080-0.400702.902702.00590K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PARL is not available on ENCORE database.





26 RBPs can affect the splicing of PARL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.227000.000100.02626includedK562FTO
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558428-0.281000.000000.00000excludedK562SF3B4
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558406-0.195000.000020.00144excludedK562PRPF8
SEPARLENSG00000175193.8chr3-183560085183560235183558357183558428183562018183562114-0.188000.000020.00159excludedK562PRPF8
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584060.173000.000000.00124includedK562WDR3
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558428-0.385000.000000.00000excludedHepG2U2AF1
SEPARLENSG00000175193.8chr3-183560085183560235183558357183558428183562018183562114-0.320000.000010.00042excludedHepG2U2AF1
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.061000.003930.08751includedK562AKAP8L
SEPARLENSG00000175193.8chr3-183560085183560235183558357183558428183562018183562114-0.144000.003100.06632excludedHepG2HNRNPK
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558428-0.255000.000000.00000excludedHepG2U2AF2
SEPARLENSG00000175193.8chr3-183560085183560235183558357183558428183562018183562114-0.217000.000010.00015excludedHepG2U2AF2
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.234000.000000.00081includedK562METAP2
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551407183558357183558428-0.076000.002540.02676excludedK562AQR
SEPARLENSG00000175193.8chr3-183560085183560235183558357183558428183562018183562114-0.110000.001210.01431excludedK562AQR
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558406-0.263000.000000.00000excludedK562FXR1
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.238000.000000.00255includedK562GPKOW
SEPARLENSG00000175193.8chr3-183551279183551377183547177183547497183558357183558428-0.151000.000100.03034excludedK562GPKOW
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.156000.000590.07602includedK562LARP4
SEPARLENSG00000175193.8chr3-183560085183560235183558357183558428183562018183562114-0.184000.000260.01831excludedK562EFTUD2
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558428-0.284000.000000.00000excludedK562U2AF1
SEPARLENSG00000175193.8chr3-183560085183560235183558362183558428183562018183562114-0.206000.000020.00097excludedK562U2AF1
SEPARLENSG00000175193.8chr3-1835742191835743391835620181835621141835805401835805890.057000.000020.00422includedHepG2DDX6
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.139000.000050.01513includedHepG2HNRNPUL1
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.208000.000000.00324includedK562SBDS
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558428-0.149000.000200.00851excludedHepG2SF3A3
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.152000.000310.02874includedK562HNRNPUL1
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558428-0.140000.000000.00031excludedHepG2SF3B4
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.137000.000050.01468includedK562UPF1
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558428-0.317000.000000.00000excludedK562U2AF2
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.271000.000000.00003includedK562CPSF6
SEPARLENSG00000175193.8chr3-183560085183560235183558357183558428183562018183562114-0.151000.000040.00332excludedK562HNRNPK
SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.117000.000010.00062includedHepG2HNRNPU
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558428-0.140000.000320.01649excludedK562PTBP1
SEPARLENSG00000175193.8chr3-183551511183551613183551279183551377183558357183558406-0.172000.003960.05791excludedK562HNRNPC
SEPARLENSG00000175193.8chr3-183560085183560235183558357183558428183562018183562114-0.368000.000000.00005excludedK562HNRNPC
A3SSPARLENSG00000175193.8chr3-1835512791835514331835512791835513771835515111835516130.078000.000000.00000longerK562AQR
A5SSPARLENSG00000175193.8chr3-183580484183580589183580540183580589183562018183562114-0.067000.000090.01568shorterK562RBM22
A5SSPARLENSG00000175193.8chr3-1835804841835805891835805401835805891835620181835621140.062000.000730.08536longerHepG2SFPQ
A5SSPARLENSG00000175193.8chr3-1835804841835805891835805401835805891835620181835621140.096000.001320.08429longerK562HNRNPC
A5SSPARLENSG00000175193.8chr3-1835804841835805891835805401835805891835620181835621140.098000.000090.05574longerK562GPKOW
A5SSPARLENSG00000175193.8chr3-1835804841835805891835805401835805891835620181835621140.085000.000100.05408longerK562FMR1
A5SSPARLENSG00000175193.8chr3-1835804841835805891835805401835805891835620181835621140.163000.000000.00096longerHepG2DDX6
A5SSPARLENSG00000175193.8chr3-1835804841835805891835805401835805891835620181835621140.080000.000060.04034longerK562LARP4
MXEPARLENSG00000175193.8chr3-183580540183580589183584412183584553183562018183562114183585652183585848-0.131000.003320.053152includedHepG2U2AF1
MXEPARLENSG00000175193.8chr3-1835600851835602351835620181835621721835583571835584281835805401835805890.126000.001350.011811includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PARL is not avaliable on ENCORE database.