HADHB

General Information

Gene Name       : HADHB
Gene ID             : ENSG00000138029.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HADHB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HADHBENSG00000138029.1348.2245.5846.90ENCSR000AEF
HepG2HADHBENSG00000138029.1395.85129.00112.42ENCSR985KAT
K562HADHBENSG00000138029.1355.8661.8758.86ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HADHB is not avaliable on ENCORE database.



Proteins bound to RNA
  • HADHB RNA is bound by 24 proteins.  







eCLIP assay for HADHB is not avaliable on ENCORE database.





24 proteins are bound to HADHB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr22651280926512871+3'-UTR,CDS3.178596.85038HepG2G3BP1
chr22651283926512882+3'-UTR4.284766.66283HepG2SUB1
chr22651316526513220+3'-UTR6.2792511.71673HepG2SUB1
chr22651309526513208+3'-UTR3.4496421.85689K562PUM2
chr22651315126513221+3'-UTR3.677053.68079HepG2FUBP3
chr22651316926513233+3'-UTR3.782248.41415K562PABPC4
chr22647726226477362+5'-UTR,CDS,intron-Proximal3.126533.01637HepG2AQR
chr22647729626477342+5'-UTR,CDS,intron-Proximal3.465807.57536HepG2G3BP1
chr22648376626483860+5'-UTR,intron-Distal,intron-Proximal4.613235.76788K562MATR3
chr22648381526483877+5'-UTR,intron-Distal,intron-Proximal5.368229.56266K562AQR
chr22646785526467902+5'-UTR,intron-Distal,intron-Proximal4.277777.99161HepG2PRPF8
chr22646782226467863+5'-UTR,intron-Distal,intron-Proximal4.539794.15208K562RBM15
chr22646780326467860+5'-UTR,intron-Distal,intron-Proximal3.7762414.94047K562DDX3X
chr22650201226502077+CDS,intron-Distal3.635249.50663HepG2RPS3
chr22649652026496550+CDS4.217414.16554HepG2PPIG
chr22648624726486289+CDS,intron-Proximal4.047555.48237HepG2G3BP1
chr22649282026492835+CDS,intron-Distal,intron-Proximal3.219594.31744K562YBX3
chr22649651926496557+CDS3.200324.55847HepG2G3BP1
chr22650286126502966+CDS,intron-Proximal3.630119.60317HepG2G3BP1
chr22650839426508440+CDS,intron-Proximal3.066494.22993HepG2LARP4
chr22650571526505772+CDS4.250267.49468HepG2BCLAF1
chr22649657226496619+CDS,intron-Proximal3.245427.18951HepG2G3BP1
chr22650200226502089+CDS,intron-Distal,intron-Proximal3.869349.05854HepG2G3BP1
chr22650587526505918+CDS3.958385.48237HepG2G3BP1
chr22650573426505807+CDS,intron-Proximal4.082687.87148HepG2PRPF8
chr22650202126502076+CDS,intron-Distal4.091267.05793K562RPS3
chr22650830426508366+CDS4.461848.25459HepG2RPS3
chr22651272326512799+CDS,intron-Proximal5.367674.90235K562SF3B4
chr22650779426507825+CDS3.143343.17233HepG2BCLAF1
chr22651278426512809+CDS,intron-Proximal3.755078.03852HepG2G3BP1
chr22649657326496619+CDS,intron-Proximal3.129584.00731K562UCHL5
chr22650293926503004+CDS,intron-Proximal4.297846.23016HepG2PRPF8
chr22650151426501588+CDS,intron-Distal3.922879.88634HepG2G3BP1
chr22650290226502979+CDS3.189723.68647K562SND1
chr22650776026507821+CDS4.139424.23668K562LIN28B
chr22650215326502182+CDS,intron-Distal3.252673.24162HepG2G3BP1
chr22650702626507073+CDS,intron-Proximal3.166213.29600K562LIN28B
chr22649994026499980+CDS,intron-Proximal3.646668.03852HepG2G3BP1
chr22650830126508390+CDS3.174035.51984K562UCHL5
chr22650829426508374+CDS3.342827.45446HepG2G3BP1
chr22647930826479404+intron-Distal3.090845.20739K562KHSRP
chr22648424426484303+intron-Distal4.187575.75812K562PTBP1
chr22649208226492155+intron-Distal3.849853.72818HepG2ILF3
chr22647888526478998+intron-Distal3.476259.83419K562KHSRP
chr22650806226508127+intron-Distal3.803353.45805K562KHSRP
chr22650904926509178+intron-Distal4.458989.65962K562QKI
chr22647752726477607+intron-Distal3.010924.36251K562PRPF8
chr22649620926496342+intron-Distal5.579366.23225K562QKI
chr22647869826478802+intron-Distal4.480725.10338HepG2KHSRP
chr22648226526482332+intron-Distal3.484863.16095HepG2U2AF2
chr22648473226484909+intron-Distal3.809205.47496K562MATR3
chr22647736926477425+intron-Proximal4.242494.54401K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HADHB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HADHB is not available on ENCORE database.

  • 108 RBPs can affect the levels of HADHB.  








The Knockdown/knockout RNA-Seq assay for HADHB is not available on ENCORE database.





108 RBPs can affect the gene expression of HADHB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HADHBENSG00000138029.94205.982802722.125300.627607.779806.31390HepG2ABCF1
HADHBENSG00000138029.92285.799902727.39200-0.254803.885303.18780HepG2ACO1
HADHBENSG00000138029.93058.600404471.42780-0.547904.084803.13870HepG2ASCC1
HADHBENSG00000138029.92295.426302958.71290-0.366202.258801.41600HepG2BCCIP
HADHBENSG00000138029.92600.571601842.406100.497105.946605.10950HepG2BOP1
HADHBENSG00000138029.92997.924702247.095600.415805.662604.61130HepG2CALR
HADHBENSG00000138029.96826.601804248.103300.6842010.353508.94320HepG2CIRBP
HADHBENSG00000138029.93374.083102726.626600.307306.464605.52540HepG2CKAP4
HADHBENSG00000138029.92197.970201691.419500.377803.299302.55500HepG2CPSF6
HADHBENSG00000138029.93182.170203828.93700-0.266903.561802.85110HepG2CELF1
HADHBENSG00000138029.93063.264102522.367500.280205.015803.93820HepG2DDX19B
HADHBENSG00000138029.94037.768302405.779400.7470013.7694012.39570HepG2DDX21
HADHBENSG00000138029.93508.472102353.271400.576109.782908.11060HepG2DDX24
HADHBENSG00000138029.97273.177605176.892400.490404.936204.12020HepG2DDX3X
HADHBENSG00000138029.93606.361202339.388000.624308.640606.97140HepG2DDX5
HADHBENSG00000138029.92528.118504446.10450-0.814507.785006.79870HepG2DDX6
HADHBENSG00000138029.93609.798902288.593800.657404.987403.69200HepG2DHX30
HADHBENSG00000138029.94785.958702609.330400.8750037.6831035.93840HepG2DKC1
HADHBENSG00000138029.91996.371902372.85750-0.249202.773102.06940HepG2DNAJC21
HADHBENSG00000138029.93363.191102255.056100.576605.368804.12180HepG2EEF2
HADHBENSG00000138029.93233.586704275.09410-0.402802.559401.98940HepG2EIF2S1
HADHBENSG00000138029.92721.285402271.223900.260702.319601.32870HepG2EIF3G
HADHBENSG00000138029.96600.054904724.939100.482104.456003.64810HepG2EIF4A3
HADHBENSG00000138029.93428.749004599.51800-0.423802.696302.01590HepG2EIF4B
HADHBENSG00000138029.93443.638904061.69890-0.238103.361702.45510HepG2EIF4G1
HADHBENSG00000138029.94193.423204992.40410-0.251603.684303.00720HepG2ETF1
HADHBENSG00000138029.93280.230002664.996100.299602.957002.09660HepG2EWSR1
HADHBENSG00000138029.91893.672902748.68870-0.537604.773303.78520HepG2FIP1L1
HADHBENSG00000138029.93566.461704765.88100-0.418202.895302.18700HepG2FXR1
HADHBENSG00000138029.92723.901304421.78180-0.699005.799104.85010HepG2G3BP1
HADHBENSG00000138029.92166.338702603.77390-0.265303.668802.55610HepG2HDGF
HADHBENSG00000138029.93332.144402664.613500.322403.051402.32770HepG2HNRNPC
HADHBENSG00000138029.93035.981904475.75420-0.560004.833703.93020HepG2HNRNPK
HADHBENSG00000138029.93090.999403750.11070-0.278905.663304.72970HepG2HNRNPL
HADHBENSG00000138029.92545.369301829.745000.476104.769403.96570HepG2HNRNPLL
HADHBENSG00000138029.91507.951201896.46460-0.330703.098602.09370HepG2HNRNPM
HADHBENSG00000138029.93465.881902877.936100.268102.486901.79920HepG2IGF2BP1
HADHBENSG00000138029.92435.694604494.90360-0.884007.638806.57300HepG2IGF2BP2
HADHBENSG00000138029.95999.707904767.538600.331502.668802.02440HepG2MAGOH
HADHBENSG00000138029.91855.404802224.58890-0.261802.147201.42990HepG2MSI2
HADHBENSG00000138029.92353.312704082.29790-0.7947021.7664019.75950HepG2NOL12
HADHBENSG00000138029.92001.774101622.438200.303002.300901.61650HepG2NSUN2
HADHBENSG00000138029.91991.220802620.12150-0.396007.135105.87680HepG2PARN
HADHBENSG00000138029.93407.838404489.62220-0.397709.007508.01500HepG2PCBP1
HADHBENSG00000138029.91947.617002360.91820-0.277603.235202.44380HepG2PPIL4
HADHBENSG00000138029.92384.248302086.249200.192501.981801.31950HepG2PRPF4
HADHBENSG00000138029.92736.264602244.383700.285802.182501.46260HepG2PRPF8
HADHBENSG00000138029.93726.570004568.32550-0.293804.780104.10370HepG2PTBP1
HADHBENSG00000138029.93429.282804136.84650-0.270605.804505.01000HepG2PUM1
HADHBENSG00000138029.93459.761604133.79090-0.256802.691602.02990HepG2PUM2
HADHBENSG00000138029.93513.887902778.000400.338906.959006.05870HepG2PUS1
HADHBENSG00000138029.93159.896604947.67970-0.6469016.2022014.86870HepG2QKI
HADHBENSG00000138029.92274.216702947.14180-0.373903.448702.49970HepG2RBM15
HADHBENSG00000138029.92304.598403017.42300-0.388803.280602.19430HepG2RBM27
HADHBENSG00000138029.94196.253805084.13510-0.276904.786504.11010HepG2NELFE
HADHBENSG00000138029.93178.474604735.13120-0.5751018.0027016.65590HepG2RECQL
HADHBENSG00000138029.93864.885903148.720200.295602.348201.71050HepG2RPLP0
HADHBENSG00000138029.93796.982402689.374400.497503.097602.09960HepG2RPS10
HADHBENSG00000138029.92930.170401905.258500.620905.160304.06760HepG2RPS3A
HADHBENSG00000138029.92342.699901811.070800.371203.413902.63720HepG2SF3B1
HADHBENSG00000138029.93358.583304756.27570-0.5020013.9419012.77320HepG2SF3B4
HADHBENSG00000138029.94144.732703736.686100.149402.168301.53440HepG2SLBP
HADHBENSG00000138029.92258.354902749.03600-0.283705.538304.67930HepG2SMN1
HADHBENSG00000138029.91914.485804712.99090-1.2997089.0432087.22770HepG2SRFBP1
HADHBENSG00000138029.97270.838104964.497900.5504020.2558019.22420HepG2SRSF1
HADHBENSG00000138029.93283.833303847.74270-0.228603.093302.43630HepG2SRSF5
HADHBENSG00000138029.92572.929704038.86270-0.6505023.0701021.76220HepG2SRSF9
HADHBENSG00000138029.96213.392004092.045600.6025022.4312021.27830HepG2SSB
HADHBENSG00000138029.91226.806501657.25910-0.433902.756801.65850HepG2STIP1
HADHBENSG00000138029.93496.717304375.88770-0.323607.113906.19680HepG2SUCLG1
HADHBENSG00000138029.92238.895801856.029200.270502.254401.40200HepG2SUPT6H
HADHBENSG00000138029.93488.237404462.21730-0.355305.837705.07460HepG2TAF15
HADHBENSG00000138029.92421.824901783.505200.441304.587603.68580HepG2TARDBP
HADHBENSG00000138029.93240.763402197.338100.560502.352301.36810HepG2TBRG4
HADHBENSG00000138029.92953.710204100.24090-0.473207.242505.90120HepG2TIA1
HADHBENSG00000138029.93823.441202572.190400.5718011.0384010.15410HepG2TIAL1
HADHBENSG00000138029.92063.286302595.03800-0.330805.400204.66350HepG2TRIM56
HADHBENSG00000138029.91840.379302351.31320-0.353502.924802.27990HepG2U2AF1
HADHBENSG00000138029.91614.609202867.18730-0.828502.361001.45880HepG2U2AF2
HADHBENSG00000138029.91325.812201710.78590-0.367802.576801.84500HepG2UCHL5
HADHBENSG00000138029.93297.886202876.125400.197302.399901.74200HepG2UPF1
HADHBENSG00000138029.92391.998602956.18520-0.305502.840901.78080HepG2UTP18
HADHBENSG00000138029.92401.015102776.77190-0.209802.208101.65960HepG2UTP3
HADHBENSG00000138029.93759.435202850.724400.399103.934103.07700HepG2XRN2
HADHBENSG00000138029.92549.028702058.905300.308005.502104.60630HepG2ZC3H8
HADHBENSG00000138029.93701.528203163.174300.226603.074102.50650HepG2ZNF622
HADHBENSG00000138029.93159.337202486.557300.345406.271705.47010K562AGGF1
HADHBENSG00000138029.91948.325103592.31260-0.8827017.1013015.80510K562AQR
HADHBENSG00000138029.9717.97930927.23640-0.369002.564301.55770K562CCAR1
HADHBENSG00000138029.92208.438302659.93310-0.268403.562002.83500K562DDX47
HADHBENSG00000138029.93217.719002784.222600.208702.303401.51490K562DKC1
HADHBENSG00000138029.91118.796001767.30630-0.659608.058806.43350K562EFTUD2
HADHBENSG00000138029.9607.17160943.19160-0.635403.498102.35410K562EIF3A
HADHBENSG00000138029.9837.800701067.91730-0.350102.200201.38920K562FTO
HADHBENSG00000138029.91696.803902017.98510-0.250102.471301.39810K562GLRX3
HADHBENSG00000138029.9714.422001182.34730-0.726809.440607.96400K562GPKOW
HADHBENSG00000138029.92403.030703338.18420-0.474206.527005.35950K562GRSF1
HADHBENSG00000138029.91130.998601778.14750-0.652809.683708.62170K562HNRNPC
HADHBENSG00000138029.91261.686101587.84560-0.331702.463001.39770K562HNRNPF
HADHBENSG00000138029.91775.373602419.76400-0.446703.434502.24710K562IGF2BP2
HADHBENSG00000138029.91675.937202121.65640-0.340205.433504.32310K562MTPAP
HADHBENSG00000138029.92881.928402156.092000.418502.822101.92970K562NAA15
HADHBENSG00000138029.92070.725302357.30470-0.187002.603201.87610K562NSUN2
HADHBENSG00000138029.91369.815802263.09480-0.7243011.830009.72760K562PCBP2
HADHBENSG00000138029.91132.444501594.28370-0.493505.165203.87880K562PSIP1
HADHBENSG00000138029.92985.141402471.081400.272602.636101.98540K562PTBP1
HADHBENSG00000138029.93134.136704303.59490-0.457505.335604.20630K562PUF60
HADHBENSG00000138029.94435.845402565.991900.7896014.3480013.15340K562PUS1
HADHBENSG00000138029.93053.157702500.148200.288203.517002.86170K562RBM15
HADHBENSG00000138029.91837.034302369.66870-0.367303.436802.49470K562RBM22
HADHBENSG00000138029.9959.325601232.99510-0.362103.004701.87750K562SAFB
HADHBENSG00000138029.91596.448601989.72880-0.317703.370202.42480K562SF3B4
HADHBENSG00000138029.91039.411501378.85240-0.407703.463102.28210K562SRFBP1
HADHBENSG00000138029.93075.736902422.443200.344403.901203.06680K562SRSF1
HADHBENSG00000138029.9932.173301279.57320-0.457004.590803.17330K562SRSF4
HADHBENSG00000138029.91187.163901665.19980-0.488203.975802.74230K562SUPV3L1
HADHBENSG00000138029.91785.698202451.75770-0.457304.619603.69940K562TARDBP
HADHBENSG00000138029.91321.254201629.01950-0.302102.291101.44260K562TRIM56
HADHBENSG00000138029.91734.014102138.74050-0.302602.824001.93810K562WDR3
HADHBENSG00000138029.91919.530902224.08290-0.212502.659401.82830K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HADHB is not available on ENCORE database.





10 RBPs can affect the splicing of HADHB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHADHBENSG00000138029.9chr2+2648384826483931264772972647734226486247264863470.108000.000000.00000includedK562AQR
SEHADHBENSG00000138029.9chr2+264927582649286526486247264863472649651826496618-0.059000.000390.00553excludedK562AQR
SEHADHBENSG00000138029.9chr2+2648384826483931264772972647734226486247264863470.060000.000150.04299includedK562GPKOW
SEHADHBENSG00000138029.9chr2+265082742650835726507750265078252651278526513332-0.073000.000000.00019excludedHepG2SRSF1
SEHADHBENSG00000138029.9chr2+265082742650843926507750265078252651278526513280-0.058000.000010.00067excludedK562TARDBP
SEHADHBENSG00000138029.9chr2+2648384826483931264772802647734226486247264863470.052000.000270.03681includedK562CPSF6
A3SSHADHBENSG00000138029.9chr2+2647728026477342264772972647734226477114264771860.136000.000000.00000longerK562U2AF2
A3SSHADHBENSG00000138029.9chr2+2647728026477342264772972647734226477114264771860.158000.000000.00000longerK562AQR
A3SSHADHBENSG00000138029.9chr2+2647728026477342264772972647734226477114264771860.089000.000000.00000longerHepG2U2AF1
A3SSHADHBENSG00000138029.9chr2+2647728026477342264772972647734226477114264771860.142000.000000.00000longerK562U2AF1
MXEHADHBENSG00000138029.9chr2+26486247264863472649282026492865264772972647734226496518264966180.141000.004410.094911includedK562XRN2
MXEHADHBENSG00000138029.9chr2+26486220264863472649282026492865264772972647734226496518264966180.053000.000520.005161includedK562AQR
MXEHADHBENSG00000138029.9chr2+26477280264773422648624726486347264771142647718626492820264928650.063000.000000.000001includedK562AQR
MXEHADHBENSG00000138029.9chr2+26486247264863472649282026492865264677622646785826496518264966180.054000.000950.008761includedK562AQR
MXEHADHBENSG00000138029.9chr2+2647729726477342264862472648634726477114264771862649651826496618-0.100000.000010.000222includedK562AQR
MXEHADHBENSG00000138029.9chr2+26486247264863472649282026492865264772972647734226496518264966180.120000.000370.016991includedHepG2XRN2
MXEHADHBENSG00000138029.9chr2+26486247264863472649282026492865264772972647734226496518264966180.131000.000120.004671includedHepG2DDX55
MXEHADHBENSG00000138029.9chr2+26477297264773422648624726486347264771142647718626492820264928650.092000.004330.074341includedHepG2DDX55
MXEHADHBENSG00000138029.9chr2+26499940265000282650148126501669264965182649661826502002265021830.063000.001470.030591includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HADHB is not avaliable on ENCORE database.