MAX

General Information

Gene Name       : MAX
Gene ID             : ENSG00000125952.18
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MAX)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAXENSG00000125952.1841.6758.1249.89ENCSR000AEF
HepG2MAXENSG00000125952.1823.7724.7824.27ENCSR985KAT
K562MAXENSG00000125952.1845.7557.0051.38ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAX is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAX RNA is bound by 24 proteins.  







eCLIP assay for MAX is not avaliable on ENCORE database.





24 proteins are bound to MAX RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr146554197265542029-3'-UTR,intron-Distal3.410415.78757K562UPF1
chr146554214465542254-3'-UTR,intron-Distal,intron-Proximal4.2592717.28617K562PUM2
chr146554230065542343-3'-UTR,intron-Distal4.310637.49447K562UPF1
chr146554235265542416-3'-UTR,intron-Distal4.7236814.74404K562UPF1
chr146554244365542492-3'-UTR,intron-Distal4.118868.58756K562LIN28B
chr146554196265542020-3'-UTR,intron-Distal4.225308.40176K562TIA1
chr146554287165542928-3'-UTR,intron-Distal3.526159.55885K562FAM120A
chr146554288465542922-3'-UTR,intron-Distal3.293704.26467K562UPF1
chr146554249265542542-3'-UTR,intron-Distal4.078434.23668K562LIN28B
chr146554335065543469-3'-UTR,CDS,intron-Distal5.0801316.59090K562SF3B4
chr146554231165542359-3'-UTR,intron-Distal4.602489.58395K562FAM120A
chr146554210565542155-3'-UTR,intron-Distal4.478717.33240HepG2PCBP2
chr146554294765542986-3'-UTR,intron-Distal3.410604.09267K562FAM120A
chr146554279265542942-3'-UTR,intron-Distal,intron-Proximal3.575865.09017HepG2UPF1
chr146554199565542006-3'-UTR,intron-Distal3.317323.37207K562FAM120A
chr146554193765542027-3'-UTR,intron-Distal4.028773.04397HepG2TIA1
chr146554324465543282-3'-UTR,CDS,intron-Distal,intron-Proximal4.004593.48187K562RBM15
chr146554330565543424-3'-UTR,CDS,intron-Distal,intron-Proximal3.464685.76243HepG2BUD13
chr146556909865569216-5'-UTR,intron-Distal,intron-Proximal4.2549515.79210K562TARDBP
chr146556824865568302-5'-UTR,CDS,intron-Distal,intron-Proximal5.362308.57494HepG2U2AF2
chr146556824365568297-5'-UTR,CDS,intron-Distal,intron-Proximal3.983393.00996K562BUD13
chr146556912265569204-5'-UTR,intron-Distal,intron-Proximal4.9940327.26172K562UCHL5
chr146556042065560527-5'-UTR,CDS,intron-Distal,intron-Proximal3.158965.38953K562ZNF622
chr146556911265569207-5'-UTR,intron-Distal,intron-Proximal4.871876.45994HepG2DKC1
chr146556910765569205-5'-UTR,intron-Distal,intron-Proximal3.8405211.24043K562ZNF622
chr146556912665569213-5'-UTR,intron-Distal,intron-Proximal3.262236.10115HepG2IGF2BP1
chr146556912065569204-5'-UTR,intron-Distal,intron-Proximal4.5144410.89658HepG2BCLAF1
chr146556824465568303-5'-UTR,CDS,intron-Distal,intron-Proximal3.504384.66077K562U2AF2
chr146556914465569201-5'-UTR,intron-Distal,intron-Proximal4.4887413.39138K562IGF2BP1
chr146556911265569198-5'-UTR,intron-Distal,intron-Proximal3.551347.43070K562DDX24
chr146556912365569207-5'-UTR,intron-Distal,intron-Proximal3.383473.45199HepG2SRSF7
chr146556911165569144-5'-UTR,intron-Distal,intron-Proximal4.225797.73013K562IGF2BP1
chr146556911665569207-5'-UTR,intron-Distal,intron-Proximal5.4494859.06175K562EIF4G2
chr146556905865569116-5'-UTR,intron-Distal,intron-Proximal4.1159816.84064K562EIF4G2
chr146556897165569023-CDS,intron-Distal4.060864.98250K562AQR
chr146554458165544609-CDS,intron-Distal,intron-Proximal6.0208413.72936K562AQR
chr146554460965544632-CDS,intron-Distal,intron-Proximal5.8659811.65826K562AQR
chr146556146465561520-intron-Distal4.497284.38558HepG2HNRNPM
chr146554479765544887-intron-Distal,intron-Proximal3.749493.11181HepG2CSTF2
chr146556871065568775-intron-Distal4.038005.49785HepG2XRN2
chr146554170965541839-intron-Distal,intron-Proximal4.387845.06031HepG2CSTF2
chr146553009965530183-intron-Distal4.613524.85866HepG2QKI
chr146554707565547125-intron-Distal3.863553.16986HepG2QKI
chr146556066665560758-intron-Distal3.616373.91876HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAX is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAX is not available on ENCORE database.

  • 55 RBPs can affect the levels of MAX.  








The Knockdown/knockout RNA-Seq assay for MAX is not available on ENCORE database.





55 RBPs can affect the gene expression of MAX :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAXENSG00000125952.14475.35270964.76780-1.0212011.050209.37190HepG2ABCF1
MAXENSG00000125952.14363.17790527.22840-0.537805.077604.06490HepG2AKAP8L
MAXENSG00000125952.14421.92350602.58020-0.514203.262802.41030HepG2ASCC1
MAXENSG00000125952.14863.58730674.905800.355603.380302.63470HepG2AUH
MAXENSG00000125952.14725.44700909.71890-0.326602.101201.57490HepG2BOP1
MAXENSG00000125952.14399.69350524.64640-0.392503.279902.56620HepG2CKAP4
MAXENSG00000125952.14753.65220594.774500.341502.993002.32900HepG2CELF1
MAXENSG00000125952.141122.35490697.624100.685906.587905.66480HepG2DDX3X
MAXENSG00000125952.14338.86330462.37880-0.448402.485401.43440HepG2EFTUD2
MAXENSG00000125952.14871.76150619.874400.491902.649901.97600HepG2EIF4B
MAXENSG00000125952.14891.16720604.379700.560105.135504.04610HepG2EIF4G2
MAXENSG00000125952.14353.03450512.78600-0.538504.130303.10980HepG2EWSR1
MAXENSG00000125952.141237.21760974.217000.344702.063801.39420HepG2FIP1L1
MAXENSG00000125952.14661.58300550.783300.264302.268201.59570HepG2ILF2
MAXENSG00000125952.14234.21960646.18190-1.4641017.4985016.01850HepG2MATR3
MAXENSG00000125952.14740.71850533.714800.472805.035703.93810HepG2PARN
MAXENSG00000125952.14400.58610605.32310-0.595604.856904.09410HepG2PUF60
MAXENSG00000125952.14896.29640642.594800.480007.131906.27020HepG2PUM1
MAXENSG00000125952.14494.30050642.11440-0.377402.548701.90450HepG2PUM2
MAXENSG00000125952.14886.867801100.32240-0.311102.308501.51680HepG2RBM15
MAXENSG00000125952.14835.51400647.671000.367303.130902.58860HepG2RBM22
MAXENSG00000125952.14534.24020703.65980-0.397403.287002.70790HepG2NELFE
MAXENSG00000125952.141178.11650894.312500.397503.177602.42320HepG2SF3B1
MAXENSG00000125952.141449.19180731.513000.9862028.7209027.54780HepG2SRFBP1
MAXENSG00000125952.14483.32270687.09350-0.507505.112104.52040HepG2SRSF1
MAXENSG00000125952.14549.57620679.71950-0.306602.364101.78090HepG2SUCLG1
MAXENSG00000125952.141349.59110833.462300.695208.008106.94050HepG2U2AF1
MAXENSG00000125952.14333.78730244.863400.446901.956301.31820HepG2UCHL5
MAXENSG00000125952.141053.923302442.68160-1.212708.024505.97340K562ABCF1
MAXENSG00000125952.141317.893001666.76340-0.338804.594503.89530K562AGGF1
MAXENSG00000125952.141277.824401701.36930-0.413003.502202.52080K562BOP1
MAXENSG00000125952.141656.495001991.95970-0.266102.530501.41310K562CCDC124
MAXENSG00000125952.141529.769702010.00520-0.393904.096802.73270K562CPEB4
MAXENSG00000125952.141387.854501809.02350-0.382404.131103.17160K562CPSF6
MAXENSG00000125952.142013.800602582.90150-0.359104.243503.02620K562CELF1
MAXENSG00000125952.142707.058702080.436400.379705.273804.41430K562DDX47
MAXENSG00000125952.141261.54680720.523400.808005.706604.22570K562EIF3A
MAXENSG00000125952.141786.198702100.69490-0.234002.329801.46270K562EIF4G2
MAXENSG00000125952.141179.553401560.15740-0.403503.243102.24740K562FTO
MAXENSG00000125952.141052.28670745.873200.496406.258305.40260K562FXR1
MAXENSG00000125952.141043.779801358.14660-0.379804.328702.90600K562GLRX3
MAXENSG00000125952.141407.433101727.15600-0.295302.347601.61500K562GPKOW
MAXENSG00000125952.141464.912101879.99190-0.359903.400802.21380K562HNRNPL
MAXENSG00000125952.14686.14970880.61130-0.360002.637501.48400K562IGF2BP3
MAXENSG00000125952.141273.42240960.022400.407503.662402.01360K562LARP7
MAXENSG00000125952.14668.06950907.79270-0.442404.049102.91650K562MATR3
MAXENSG00000125952.141301.992601685.90380-0.372803.364402.39590K562METAP2
MAXENSG00000125952.141726.521702239.14150-0.375103.261002.03080K562MSI2
MAXENSG00000125952.141114.658001427.91640-0.357304.876803.82620K562MTPAP
MAXENSG00000125952.141282.098701586.53000-0.307404.822103.87490K562NSUN2
MAXENSG00000125952.141918.235602388.68870-0.316403.869302.73110K562PUM2
MAXENSG00000125952.141145.28340884.855000.372102.387601.46570K562RPS3
MAXENSG00000125952.141498.26120960.837900.640808.706206.84750K562SAFB
MAXENSG00000125952.14863.21770687.662700.327902.545801.72710K562SF3B4
MAXENSG00000125952.141902.812501081.595300.814906.847205.54390K562SYNCRIP
MAXENSG00000125952.141354.481002054.52340-0.601102.985201.53450K562TRIP6
MAXENSG00000125952.141319.656001564.45660-0.245502.664301.42040K562TROVE2
MAXENSG00000125952.141371.533702003.96150-0.547103.948602.50400K562UTP3
MAXENSG00000125952.141180.800401439.43140-0.285702.298501.49980K562WDR3
MAXENSG00000125952.141743.308201496.853500.219802.570001.75170K562WDR43
MAXENSG00000125952.141278.561101735.22030-0.440604.605503.44960K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAX is not available on ENCORE database.





28 RBPs can affect the splicing of MAX :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655691880.385000.000000.00018includedK562SRSF1
SEMAXENSG00000125952.14chr14-655440456554414665543175655433816554463065544754-0.164000.002180.03904excludedK562SRSF1
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.117000.000260.05821includedK562WDR3
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655691880.422000.000000.00000includedHepG2U2AF1
SEMAXENSG00000125952.14chr14-655440456554414665543175655433816554463065544754-0.142000.000930.07285excludedK562XRCC6
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.112000.000000.00000includedK562FMR1
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.070000.000070.02742includedK562WDR43
SEMAXENSG00000125952.14chr14-655682636556829065560425655605336556902165569188-0.174000.000210.02780excludedHepG2DDX59
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655691880.164000.001240.08566includedHepG2TBRG4
SEMAXENSG00000125952.14chr14-655440616554414665543179655433816554463065544754-0.065000.000000.00000excludedHepG2TBRG4
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655691880.482000.000000.00000includedHepG2U2AF2
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.094000.000000.00020includedK562METAP2
SEMAXENSG00000125952.14chr14-6554404565544146655431756554338165544630655448440.276000.000000.00000includedK562AQR
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.099000.000000.00000includedK562ABCF1
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655692350.267000.000010.00113includedK562FXR1
SEMAXENSG00000125952.14chr14-655440456554414665543175655433816554463065544754-0.302000.000000.00000excludedK562FXR1
SEMAXENSG00000125952.14chr14-6554404565544146655431756554338165544630655447540.143000.000010.00306includedHepG2TIA1
SEMAXENSG00000125952.14chr14-6554404565544146655431756554338165544630655447540.157000.001340.09085includedK562SUPV3L1
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.095000.000010.00266includedK562NSUN2
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655691880.343000.000000.00033includedHepG2SFPQ
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655692060.274000.000750.09352includedHepG2HNRNPA1
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.124000.000000.00000includedK562GPKOW
SEMAXENSG00000125952.14chr14-655440616554414665543179655433816554463065544754-0.089000.000000.00046excludedK562APOBEC3C
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.283000.000010.01685includedK562SSB
SEMAXENSG00000125952.14chr14-6554406165544146655418446554338165544630655447540.134000.000030.00618includedHepG2DDX6
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655692350.445000.000000.00000includedHepG2SRSF1
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.089000.000000.00005includedK562SF3B1
SEMAXENSG00000125952.14chr14-6554404565544146655431756554338165544630655447540.172000.000040.00982includedK562ZC3H8
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655692350.294000.000060.00491includedHepG2HNRNPU
SEMAXENSG00000125952.14chr14-655440616554414665543179655433816554463065544754-0.073000.000000.00076excludedK562SAFB
SEMAXENSG00000125952.14chr14-6556826365568290655604256556053365569021655690810.299000.001000.04046includedK562PTBP1
SEMAXENSG00000125952.14chr14-655440616554414665543179655433816554463065544754-0.165000.001720.06059excludedK562PTBP1
SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.128000.000000.00012includedK562HNRNPC
A3SSMAXENSG00000125952.14chr14-6554463065544844655446306554475465560425655605330.052000.000000.00001longerK562AQR
MXEMAXENSG00000125952.14chr14-65544630655447546556042565560533655422616554338165568263655682900.196000.000000.000001includedHepG2U2AF1
MXEMAXENSG00000125952.14chr14-6556826365568290655690216556908165560425655605336556922665569408-0.365000.000000.000002includedHepG2U2AF1
MXEMAXENSG00000125952.14chr14-6556826365568290655690216556908165560425655605336556922665569408-0.205000.000770.028222includedK562PTBP1
MXEMAXENSG00000125952.14chr14-65544630655447546556042565560533655422616554338165568263655682900.211000.000100.001191includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAX is not avaliable on ENCORE database.