WTAP

General Information

Gene Name       : WTAP
Gene ID             : ENSG00000146457.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: WTAP)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WTAPENSG00000146457.1566.0461.3963.72ENCSR000AEF
HepG2WTAPENSG00000146457.1580.90112.2096.55ENCSR985KAT
K562WTAPENSG00000146457.15103.23104.66103.94ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WTAP is not avaliable on ENCORE database.



Proteins bound to RNA
  • WTAP RNA is bound by 32 proteins.  







eCLIP assay for WTAP is not avaliable on ENCORE database.





32 proteins are bound to WTAP RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6160177158160177230+3'-UTR4.336954.30850K562ZC3H11A
chr6160169346160169411+3'-UTR,CDS,intron-Proximal4.227814.13344K562GRWD1
chr6160169595160169666+3'-UTR,intron-Distal3.323427.69244K562FAM120A
chr6160169405160169464+3'-UTR,intron-Proximal5.1867810.73027HepG2GRWD1
chr6160169591160169662+3'-UTR,intron-Distal4.2695119.68973K562U2AF1
chr6160176594160176656+3'-UTR,CDS4.8446015.28381K562PUM2
chr6160176820160176929+3'-UTR3.475398.62567K562ZC3H11A
chr6160169378160169490+3'-UTR,CDS,intron-Proximal4.098749.08333HepG2PRPF8
chr6160169457160169483+3'-UTR,intron-Proximal4.470464.55903K562RBM22
chr6160169365160169440+3'-UTR,CDS,intron-Proximal3.198465.31320K562GPKOW
chr6160169603160169665+3'-UTR,intron-Distal4.5434925.61834K562U2AF2
chr6160169511160169576+3'-UTR,intron-Distal3.239223.06355HepG2KHSRP
chr6160169398160169427+3'-UTR,CDS,intron-Proximal3.111716.78249K562PRPF8
chr6160169585160169661+3'-UTR,intron-Distal5.66005400.00000HepG2U2AF2
chr6160176656160176699+3'-UTR3.977286.89197K562PUM2
chr6160169397160169459+3'-UTR,CDS,intron-Proximal3.7290812.43406K562AQR
chr6160176929160177011+3'-UTR3.161765.02670K562ZC3H11A
chr6160170118160170212+3'-UTR,intron-Distal4.1681213.28998K562PUM2
chr6160169329160169405+3'-UTR,CDS,intron-Proximal4.300609.72888HepG2GRWD1
chr6160169427160169476+3'-UTR,intron-Proximal3.192768.57993K562PRPF8
chr6160169593160169603+3'-UTR,intron-Distal3.596466.78192K562U2AF2
chr6160169585160169663+3'-UTR,intron-Distal5.0858022.80391HepG2U2AF1
chr6160169357160169482+3'-UTR,CDS,intron-Proximal3.2555913.94550HepG2BCLAF1
chr6160148733160148741+5'-UTR,intron-Distal,intron-Proximal4.440898.60557HepG2AQR
chr6160148600160148701+5'-UTR,intron-Distal3.9123235.63461HepG2DDX3X
chr6160148700160148873+5'-UTR,intron-Distal,intron-Proximal3.5328810.22136K562EFTUD2
chr6160148167160148206+5'-UTR4.191306.48236HepG2DDX3X
chr6160157289160157327+5'-UTR,CDS,intron-Proximal4.0222211.60690HepG2GRWD1
chr6160148160160148213+5'-UTR5.2986810.64820HepG2NCBP2
chr6160148335160148388+5'-UTR,intron-Proximal4.913429.43475HepG2PRPF8
chr6160148589160148644+5'-UTR,intron-Distal3.240683.75245K562BUD13
chr6160148619160148698+5'-UTR,intron-Distal3.2845111.28368HepG2NCBP2
chr6160148213160148264+5'-UTR4.644664.61711HepG2NCBP2
chr6160148727160148781+5'-UTR,intron-Distal,intron-Proximal4.077075.63763K562AQR
chr6160148729160148791+5'-UTR,intron-Distal,intron-Proximal3.130365.75838K562PRPF8
chr6160157288160157334+5'-UTR,CDS,intron-Proximal3.892373.65740K562U2AF2
chr6160148600160148642+5'-UTR,intron-Distal3.234607.39418HepG2EFTUD2
chr6160157258160157331+5'-UTR,CDS,intron-Proximal4.0787910.49952HepG2AQR
chr6160148605160148736+5'-UTR,intron-Distal,intron-Proximal3.3657511.96489K562DDX3X
chr6160148708160148737+5'-UTR,intron-Distal,intron-Proximal3.440374.65365HepG2GRWD1
chr6160174539160174648+CDS,intron-Proximal3.5406217.09012HepG2BCLAF1
chr6160164681160164744+CDS,intron-Proximal3.840096.66119K562GPKOW
chr6160176057160176099+CDS,intron-Proximal3.764967.23562HepG2BCLAF1
chr6160160059160160171+CDS,intron-Proximal3.1787510.14158HepG2BUD13
chr6160169185160169258+CDS,intron-Proximal4.1076612.76805K562BUD13
chr6160174523160174605+CDS3.305008.94850HepG2GRWD1
chr6160160069160160121+CDS,intron-Proximal3.582406.21987K562AQR
chr6160169187160169253+CDS,intron-Proximal3.671099.30359HepG2BUD13
chr6160174478160174528+CDS,intron-Proximal3.612013.02321K562U2AF2
chr6160176056160176157+CDS,intron-Proximal4.078644.06501K562GRWD1
chr6160174445160174515+CDS,intron-Proximal3.902949.45743HepG2SF3A3
chr6160163081160163221+CDS,intron-Proximal3.5954311.01899K562SF3B4
chr6160176386160176542+CDS3.7753011.94679HepG2PABPN1
chr6160174479160174526+CDS,intron-Proximal3.870458.23042HepG2U2AF2
chr6160174355160174500+CDS,intron-Distal,intron-Proximal3.3428610.01631HepG2KHSRP
chr6160176030160176095+CDS,intron-Proximal3.548886.61645HepG2BUD13
chr6160160071160160115+CDS,intron-Proximal5.014697.46464K562PRPF8
chr6160163134160163215+CDS,intron-Proximal6.1808021.61394HepG2PRPF8
chr6160160052160160119+CDS,intron-Proximal3.008363.87994K562EFTUD2
chr6160163115160163179+CDS,intron-Proximal3.178889.69173HepG2BCLAF1
chr6160164693160164783+CDS,intron-Proximal3.8142515.25871HepG2BCLAF1
chr6160160045160160124+CDS,intron-Proximal4.256265.13777HepG2PRPF8
chr6160160020160160086+CDS,intron-Proximal3.653243.40366HepG2UCHL5
chr6160160020160160107+CDS,intron-Proximal3.2540711.44176HepG2BCLAF1
chr6160176321160176383+CDS3.144083.34231K562RBM15
chr6160163125160163181+CDS,intron-Proximal4.009728.10084K562LIN28B
chr6160176099160176161+CDS4.477557.97334HepG2BCLAF1
chr6160164720160164781+CDS3.712817.44807HepG2GRWD1
chr6160171442160171481+intron-Distal4.043494.00239HepG2KHSRP
chr6160167523160167568+intron-Distal4.439564.55788HepG2QKI
chr6160166072160166116+intron-Distal3.841558.23930HepG2SUGP2
chr6160148501160148566+intron-Distal4.324164.41148HepG2GTF2F1
chr6160160115160160198+intron-Distal,intron-Proximal5.0722415.63725K562PRPF8
chr6160148554160148619+intron-Distal3.7565310.75001HepG2NCBP2
chr6160164905160165010+intron-Distal,intron-Proximal4.331268.98664K562KHSRP
chr6160148424160148468+intron-Distal,intron-Proximal3.734546.34662HepG2PRPF8
chr6160148427160148473+intron-Distal,intron-Proximal4.594446.11395HepG2GTF2F1
chr6160165264160165334+intron-Distal3.6869313.77270HepG2SUGP2
chr6160161554160161615+intron-Distal3.056923.10539K562U2AF2
chr6160148741160148773+intron-Distal,intron-Proximal5.463799.91322HepG2AQR
chr6160165056160165127+intron-Distal4.378393.89565K562PRPF8
chr6160165434160165492+intron-Distal3.182323.18966K562MATR3
chr6160148415160148467+intron-Distal,intron-Proximal6.4823116.82805HepG2FAM120A
chr6160165738160165821+intron-Distal5.6499424.85548HepG2QKI
chr6160148927160148974+intron-Distal4.969065.02942K562EFTUD2
chr6160156816160156918+intron-Distal3.896133.49896K562KHDRBS1
chr6160148745160148785+intron-Distal,intron-Proximal3.7597112.21138HepG2PRPF8
chr6160148899160148974+intron-Distal5.6040113.38060HepG2EFTUD2
chr6160160198160160253+intron-Distal4.472728.23899K562PRPF8
chr6160148467160148550+intron-Distal4.3884013.00089HepG2FAM120A
chr6160166036160166111+intron-Distal3.598773.98203K562MATR3
chr6160165168160165277+intron-Distal4.231757.83927K562MATR3
chr6160166157160166196+intron-Distal4.106056.51675HepG2SUGP2
chr6160161559160161618+intron-Distal3.844743.70903HepG2U2AF1
chr6160150081160150271+intron-Distal3.211798.12819K562KHSRP
chr6160164923160165005+intron-Distal,intron-Proximal3.977365.25185K562PRPF8
chr6160160310160160391+intron-Distal4.034288.64567K562KHSRP
chr6160165701160165802+intron-Distal3.434747.44360K562QKI
chr6160160170160160196+intron-Distal,intron-Proximal3.700687.18461HepG2KHSRP
chr6160166364160166404+intron-Distal3.681717.75281HepG2SUGP2
chr6160148743160148815+intron-Distal,intron-Proximal4.037123.29554HepG2GTF2F1
chr6160163250160163335+intron-Distal,intron-Proximal3.157537.30615K562KHSRP
chr6160151335160151468+intron-Distal3.515995.56048K562KHSRP
chr6160161553160161636+intron-Distal3.302449.69540HepG2U2AF2
chr6160165516160165545+intron-Distal3.356194.86332HepG2SUGP2
chr6160160588160160659+intron-Distal4.4937410.69368K562KHSRP
chr6160166103160166184+intron-Distal4.190818.92068K562QKI
chr6160166361160166413+intron-Distal4.086003.06015K562MATR3
chr6160167538160167617+intron-Distal4.329886.10779K562QKI
chr6160171042160171131+intron-Distal3.9715516.53044K562KHSRP
chr6160160121160160227+intron-Distal,intron-Proximal3.077073.07246K562AQR
chr6160171066160171152+intron-Distal3.608844.48983K562TIA1
chr6160174153160174203+intron-Distal3.331504.03817HepG2KHSRP
chr6160160196160160263+intron-Distal4.2772412.13829HepG2KHSRP
chr6160166118160166193+intron-Distal4.219916.08171HepG2QKI
chr6160160113160160196+intron-Distal,intron-Proximal3.5349815.98464K562KHSRP
chr6160148440160148480+intron-Distal,intron-Proximal4.071404.23256HepG2EFTUD2
chr6160165738160165802+intron-Distal4.689236.19517K562MATR3
chr6160148420160148483+intron-Distal,intron-Proximal4.817928.06849HepG2PRPF4
chr6160165759160165800+intron-Distal3.816064.83120HepG2MATR3
chr6160165422160165489+intron-Distal4.750445.01910HepG2MATR3
chr6160166547160166584+intron-Distal3.329815.35016HepG2SUGP2
chr6160166222160166294+intron-Distal4.1464710.24855HepG2SUGP2
chr6160148422160148473+intron-Distal,intron-Proximal4.353864.36078K562GTF2F1
chr6160165214160165298+intron-Distal5.300217.87294HepG2MATR3
chr6160165887160165968+intron-Distal4.312135.61842HepG2MATR3
chr6160166076160166118+intron-Distal4.496284.17759HepG2QKI
chr6160148473160148546+intron-Distal4.486394.46189K562GTF2F1
chr6160171033160171151+intron-Distal3.9072811.87912HepG2KHSRP
chr6160160414160160464+intron-Distal3.431655.25527HepG2U2AF2
chr6160148483160148537+intron-Distal4.437664.61288HepG2PRPF4
chr6160174349160174392+intron-Distal4.9369218.37957K562KHSRP
chr6160156403160156468+intron-Distal4.084593.77753HepG2ILF3
chr6160160310160160381+intron-Distal4.316419.59273HepG2KHSRP
chr6160163276160163352+intron-Distal,intron-Proximal3.127463.45218HepG2KHSRP
chr6160165893160165963+intron-Distal3.502034.03284K562MATR3
chr6160165742160165823+intron-Distal3.1840615.69165HepG2SUGP2
chr6160148417160148492+intron-Distal,intron-Proximal3.456153.48399HepG2CSTF2T
chr6160159102160159177+intron-Distal3.905523.45317HepG2HNRNPL
chr6160166059160166112+intron-Distal4.682984.66737HepG2MATR3
chr6160160124160160170+intron-Proximal4.103288.99882HepG2KHSRP
chr6160164829160164921+intron-Proximal3.417186.35796K562AQR
chr6160174392160174475+intron-Proximal4.2720321.19882K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WTAP is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WTAP is not available on ENCORE database.

  • 65 RBPs can affect the levels of WTAP.  








The Knockdown/knockout RNA-Seq assay for WTAP is not available on ENCORE database.





65 RBPs can affect the gene expression of WTAP :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WTAPENSG00000146457.102589.271103175.57040-0.294504.545103.70330HepG2AUH
WTAPENSG00000146457.102390.500001953.785900.290902.355601.79820HepG2BOP1
WTAPENSG00000146457.101468.218901793.67630-0.288902.058101.45460HepG2CPSF6
WTAPENSG00000146457.102362.325602955.38650-0.323106.490405.42320HepG2DAZAP1
WTAPENSG00000146457.101268.585501691.57410-0.415105.542103.95520HepG2DDX1
WTAPENSG00000146457.102044.017701606.383200.347503.496302.46160HepG2DDX24
WTAPENSG00000146457.101594.833702673.09200-0.745109.625908.52030HepG2DDX3X
WTAPENSG00000146457.102329.691801947.831000.258203.276702.54900HepG2DKC1
WTAPENSG00000146457.101392.986501658.68700-0.251902.490801.81920HepG2DNAJC21
WTAPENSG00000146457.101740.845301338.267000.379302.859601.94350HepG2EIF3D
WTAPENSG00000146457.101143.215101796.76240-0.652302.575501.59840HepG2FTO
WTAPENSG00000146457.101407.140501862.65430-0.404603.913303.09930HepG2HNRNPC
WTAPENSG00000146457.101952.638702364.72190-0.276203.725002.90320HepG2HNRNPF
WTAPENSG00000146457.102139.942202692.07000-0.331106.571505.57690HepG2HNRNPL
WTAPENSG00000146457.103166.996102461.974200.363202.877802.21000HepG2MAGOH
WTAPENSG00000146457.103114.619002475.806400.331102.228701.65870HepG2MATR3
WTAPENSG00000146457.101516.843402534.16850-0.740409.084907.97660HepG2NCBP2
WTAPENSG00000146457.101373.306802055.23640-0.5817012.3718010.90970HepG2PRPF4
WTAPENSG00000146457.101817.064002797.53730-0.622509.736908.71240HepG2PUF60
WTAPENSG00000146457.102459.089902000.225500.297902.368901.45920HepG2RBM27
WTAPENSG00000146457.102043.288601624.269500.331002.619901.59010HepG2RCC2
WTAPENSG00000146457.101054.419001357.89130-0.364902.256801.53970HepG2RRP9
WTAPENSG00000146457.101364.224301647.81160-0.272503.549802.83620HepG2SAFB2
WTAPENSG00000146457.104090.530102571.437700.669606.167705.13730HepG2SF3A3
WTAPENSG00000146457.103025.594303441.83970-0.186002.280601.81170HepG2SRFBP1
WTAPENSG00000146457.103642.124202519.417100.5316014.7465013.83990HepG2SRSF1
WTAPENSG00000146457.102024.993702323.26840-0.198202.185501.55830HepG2SRSF7
WTAPENSG00000146457.104129.532702988.419300.4665012.6154011.67680HepG2SSB
WTAPENSG00000146457.101548.629701814.02240-0.228202.613802.06220HepG2TRIM56
WTAPENSG00000146457.103193.933502120.829700.590607.761106.71320HepG2U2AF1
WTAPENSG00000146457.102064.624502893.09960-0.486704.339303.27700HepG2UBE2L3
WTAPENSG00000146457.103077.991802201.707300.4833011.8836010.77720HepG2UTP3
WTAPENSG00000146457.101747.426801328.560300.395303.839702.42200K562AARS
WTAPENSG00000146457.103313.783202051.262600.6919021.6914020.21090K562AGGF1
WTAPENSG00000146457.103368.003102134.408900.6580010.491009.11240K562AKAP8L
WTAPENSG00000146457.104177.127003301.949200.339103.727202.26060K562APOBEC3C
WTAPENSG00000146457.105144.582803083.330800.7385013.2076012.06140K562AQR
WTAPENSG00000146457.101314.980701789.77890-0.444705.298504.22030K562CPSF6
WTAPENSG00000146457.101117.208401361.36660-0.285202.583101.56700K562CSTF2
WTAPENSG00000146457.105254.634002802.209700.9069040.5589038.35770K562DDX47
WTAPENSG00000146457.102755.911902296.920200.262703.063402.13480K562DKC1
WTAPENSG00000146457.101526.72020820.848100.895102.796301.78640K562EIF3A
WTAPENSG00000146457.102432.885301595.406400.608605.984304.37830K562EIF3D
WTAPENSG00000146457.102088.322601506.685400.470907.247805.97050K562EIF3G
WTAPENSG00000146457.101845.572401460.814700.337202.889302.05070K562EIF4A3
WTAPENSG00000146457.104603.885803741.960100.299004.683103.47300K562EIF4G2
WTAPENSG00000146457.102105.634101519.182900.470908.041107.07770K562FXR1
WTAPENSG00000146457.102231.347601590.526400.488303.393002.59540K562G3BP2
WTAPENSG00000146457.102604.105001650.422400.657902.984701.70440K562HNRNPA2B1
WTAPENSG00000146457.101214.468201453.79250-0.259501.872401.36960K562HNRNPC
WTAPENSG00000146457.102549.580102029.198200.329202.315701.46890K562HNRNPM
WTAPENSG00000146457.104093.840203344.309300.291602.553001.78600K562HSPD1
WTAPENSG00000146457.103381.054702265.221400.577706.676605.26710K562KIF1C
WTAPENSG00000146457.101017.517701459.14550-0.520103.600402.51950K562KRR1
WTAPENSG00000146457.103252.293802537.609000.357903.717802.63720K562MBNL1
WTAPENSG00000146457.103490.138701778.673100.9724010.818708.65100K562NAA15
WTAPENSG00000146457.102299.153001443.540100.671403.113102.04760K562PABPN1
WTAPENSG00000146457.102310.436401449.995600.672009.028207.67250K562PRPF8
WTAPENSG00000146457.105285.407704342.063400.283503.812902.54000K562PUM1
WTAPENSG00000146457.105953.458802116.911601.4917046.6531044.34610K562PUS1
WTAPENSG00000146457.103608.970002062.475800.8071022.5997020.83300K562RBM15
WTAPENSG00000146457.101910.196501508.675500.340303.167701.73940K562RBM25
WTAPENSG00000146457.102095.944801476.989500.504804.527003.47920K562RPS19
WTAPENSG00000146457.102067.927201320.089600.647402.640601.47820K562SF1
WTAPENSG00000146457.102565.176401516.142700.758603.461102.03030K562SNRNP200
WTAPENSG00000146457.102582.134501858.182600.474606.597405.51470K562SRSF1
WTAPENSG00000146457.102459.238601612.024600.6092010.849109.22660K562SYNCRIP
WTAPENSG00000146457.102317.690801541.794200.588005.811704.10490K562U2AF1
WTAPENSG00000146457.102224.966501592.319100.482606.980505.71290K562U2AF2
WTAPENSG00000146457.102804.356002088.902200.424805.582804.42370K562WDR43
WTAPENSG00000146457.102258.223401477.755700.611703.043601.37240K562XRCC6
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WTAP is not available on ENCORE database.





3 RBPs can affect the splicing of WTAP :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWTAPENSG00000146457.10chr6+1601708761601710421601692221601694011601744911601746460.101000.000040.00133includedK562SRSF1
SEWTAPENSG00000146457.10chr6+1601623931601624791601600211601600771601631191601631780.056000.000310.01504includedK562PRPF8
SEWTAPENSG00000146457.10chr6+1601506521601508411601466161601483651601572891601573270.155000.000000.00000includedK562AQR
A3SSWTAPENSG00000146457.10chr6+1601572491601573271601572891601573271601486191601487350.053000.006690.03730longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WTAP is not avaliable on ENCORE database.