ABCB4

General Information

Gene Name       : ABCB4
Gene ID             : ENSG00000005471.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ABCB4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ABCB4ENSG00000005471.173.642.893.27ENCSR000AEF
HepG2ABCB4ENSG00000005471.178.288.458.36ENCSR985KAT
K562ABCB4ENSG00000005471.170.160.060.11ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ABCB4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ABCB4 RNA is bound by 10 proteins.  







eCLIP assay for ABCB4 is not avaliable on ENCORE database.





10 proteins are bound to ABCB4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr78708093787080973-CDS,intron-Distal,intron-Proximal3.952035.36555HepG2BCLAF1
chr78708226887082311-CDS,intron-Distal3.715074.46864HepG2BCLAF1
chr78703735187037412-CDS,intron-Distal,intron-Proximal3.466163.32039HepG2PPIG
chr78703735787037515-CDS,intron-Distal3.334953.85049HepG2SND1
chr78708386187083907-CDS,intron-Distal3.261623.55800HepG2BCLAF1
chr78707937687079410-CDS,intron-Distal,intron-Proximal3.665304.09885HepG2BCLAF1
chr78706910087069151-CDS,intron-Distal3.835343.14999HepG2GRWD1
chr78707419887074270-CDS,intron-Distal4.515527.97334HepG2BCLAF1
chr78710471587104778-CDS,intron-Distal3.849944.96634HepG2PPIG
chr78705612787056209-CDS,intron-Distal4.344367.09561HepG2BCLAF1
chr78709204687092121-CDS,intron-Distal,intron-Proximal5.681567.70650HepG2PRPF8
chr78708093487081040-CDS,intron-Distal,intron-Proximal3.196783.41665HepG2GRWD1
chr78707268187072760-CDS,intron-Distal3.549087.01246HepG2BCLAF1
chr78703744787037502-CDS,intron-Distal3.005163.47879HepG2PPIG
chr78704648787046584-intron-Distal,intron-Proximal4.193684.29306HepG2KHSRP
chr78706515787065213-intron-Distal3.622484.83406HepG2QKI
chr78708123487081284-intron-Distal3.189973.80334HepG2U2AF2
chr78707796187078063-intron-Distal3.442834.23286HepG2QKI
chr78703312587033213-intron-Distal4.368884.74221HepG2PTBP1
chr78710416887104240-intron-Distal5.339945.77028HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ABCB4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ABCB4 is not available on ENCORE database.

  • 96 RBPs can affect the levels of ABCB4.  








The Knockdown/knockout RNA-Seq assay for ABCB4 is not available on ENCORE database.





96 RBPs can affect the gene expression of ABCB4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ABCB4ENSG00000005471.11439.16020826.99500-0.913108.666407.13680HepG2ABCF1
ABCB4ENSG00000005471.11516.00730693.01110-0.425504.427403.69330HepG2ACO1
ABCB4ENSG00000005471.11403.177801324.16180-1.7156030.2360028.71200HepG2AKAP1
ABCB4ENSG00000005471.11282.27740481.24350-0.769704.806603.56940HepG2BCCIP
ABCB4ENSG00000005471.11594.36600418.173800.507103.097002.14270HepG2BCLAF1
ABCB4ENSG00000005471.11544.37600427.793700.347601.864401.36480HepG2BOP1
ABCB4ENSG00000005471.11445.02580735.41740-0.724708.305907.07240HepG2CALR
ABCB4ENSG00000005471.111581.200101040.917600.603106.318905.18110HepG2CIRBP
ABCB4ENSG00000005471.11926.58670650.694200.509802.516201.78850HepG2CNOT7
ABCB4ENSG00000005471.11561.69520392.732600.516103.430102.67270HepG2CPSF6
ABCB4ENSG00000005471.111152.92080681.148300.7592010.660508.65830HepG2CPSF7
ABCB4ENSG00000005471.11338.22630736.82180-1.1233016.0603014.58470HepG2DDX21
ABCB4ENSG00000005471.11529.33180721.08980-0.446003.560302.51590HepG2DDX24
ABCB4ENSG00000005471.11742.261401268.41640-0.773008.564707.51440HepG2DDX3X
ABCB4ENSG00000005471.11448.41830685.70120-0.612703.991102.78440HepG2DDX5
ABCB4ENSG00000005471.11475.47530663.01160-0.479704.635903.79930HepG2DKC1
ABCB4ENSG00000005471.11589.36470768.76510-0.383402.239001.40830HepG2EEF2
ABCB4ENSG00000005471.111007.34660678.549700.569903.975202.63440HepG2AGO1
ABCB4ENSG00000005471.11552.142001047.45280-0.9238010.948509.81660HepG2EIF2S1
ABCB4ENSG00000005471.11461.90510624.06580-0.434102.175501.36460HepG2EIF3D
ABCB4ENSG00000005471.11701.312801157.52400-0.722906.706705.70940HepG2EIF4A3
ABCB4ENSG00000005471.11791.14050981.27210-0.310702.985302.12080HepG2EIF4G1
ABCB4ENSG00000005471.11629.17390940.00100-0.579205.444304.32440HepG2EIF4G2
ABCB4ENSG00000005471.11363.51790677.15360-0.8975011.298809.63770HepG2EWSR1
ABCB4ENSG00000005471.11508.66040835.08670-0.715205.663004.60030HepG2FIP1L1
ABCB4ENSG00000005471.11640.41150393.839200.701305.291303.57620HepG2FKBP4
ABCB4ENSG00000005471.11955.73140726.445800.395703.172802.33440HepG2FUBP3
ABCB4ENSG00000005471.11887.812901167.99730-0.395702.755602.06540HepG2FXR1
ABCB4ENSG00000005471.11287.29480555.64990-0.951609.808908.17870HepG2GEMIN5
ABCB4ENSG00000005471.11616.45190445.178700.469502.659202.02950HepG2GPKOW
ABCB4ENSG00000005471.111108.82620914.112100.278502.519301.62300HepG2HNRNPA2B1
ABCB4ENSG00000005471.11441.66750697.72490-0.659705.871404.88930HepG2HNRNPC
ABCB4ENSG00000005471.11679.90330509.539500.416004.102403.24690HepG2HNRNPF
ABCB4ENSG00000005471.11716.26060906.07620-0.339103.834003.04890HepG2HNRNPL
ABCB4ENSG00000005471.11657.70350424.843500.630404.868604.05750HepG2HNRNPLL
ABCB4ENSG00000005471.11341.50670576.23020-0.754707.230305.80380HepG2HNRNPM
ABCB4ENSG00000005471.11473.03130693.11190-0.551205.255404.44070HepG2HNRNPU
ABCB4ENSG00000005471.11613.274101101.26750-0.844609.868408.67930HepG2IGF2BP2
ABCB4ENSG00000005471.11576.348501033.57050-0.842603.232602.16740HepG2IGF2BP3
ABCB4ENSG00000005471.11955.20550707.990500.432005.870704.83890HepG2ILF2
ABCB4ENSG00000005471.11914.84110633.469600.530108.254906.56920HepG2KIF1C
ABCB4ENSG00000005471.11533.16270771.02750-0.532204.130102.65070HepG2LIN28B
ABCB4ENSG00000005471.11670.518701168.40550-0.801208.896907.73350HepG2MAGOH
ABCB4ENSG00000005471.11754.129401174.92800-0.639705.447404.58660HepG2MATR3
ABCB4ENSG00000005471.11762.03410433.316500.814305.200803.84550HepG2MTPAP
ABCB4ENSG00000005471.11819.28740567.579700.529404.960703.34450HepG2NAA15
ABCB4ENSG00000005471.11569.355201202.59040-1.0787014.6334013.25330HepG2NCBP2
ABCB4ENSG00000005471.11548.15360785.69920-0.519402.836401.38650HepG2NKRF
ABCB4ENSG00000005471.11814.68000986.30870-0.275802.178701.50000HepG2NOL12
ABCB4ENSG00000005471.11720.56740376.715500.9356010.341808.97030HepG2NSUN2
ABCB4ENSG00000005471.11647.431601070.92200-0.726107.279506.11930HepG2PABPC4
ABCB4ENSG00000005471.11833.37240618.200100.430803.498502.67940HepG2PPIL4
ABCB4ENSG00000005471.111004.41120515.580800.9620020.6051018.84090HepG2PRPF4
ABCB4ENSG00000005471.11838.749401121.74490-0.419405.165604.46640HepG2PTBP1
ABCB4ENSG00000005471.11613.39150941.50870-0.618206.714505.83970HepG2PUF60
ABCB4ENSG00000005471.11758.68580999.44220-0.397605.447004.67260HepG2PUM1
ABCB4ENSG00000005471.11674.39810998.71890-0.566506.707305.67970HepG2PUM2
ABCB4ENSG00000005471.111132.65220705.869800.6821013.5441012.35840HepG2PUS1
ABCB4ENSG00000005471.11464.72420793.30180-0.7715010.625809.75550HepG2RBM22
ABCB4ENSG00000005471.11674.015001102.57100-0.710009.484708.29190HepG2RBM25
ABCB4ENSG00000005471.11521.78310885.32500-0.762807.411205.77680HepG2RBM27
ABCB4ENSG00000005471.11516.117801248.38820-1.2743035.8174034.34310HepG2NELFE
ABCB4ENSG00000005471.11806.892601162.71510-0.527007.796606.84030HepG2RECQL
ABCB4ENSG00000005471.11307.29720607.24610-0.9826012.0107010.83800HepG2RPS19
ABCB4ENSG00000005471.11464.52260816.52890-0.813808.404707.06160HepG2RPS2
ABCB4ENSG00000005471.11595.70320833.47220-0.484503.438502.23880HepG2RPS5
ABCB4ENSG00000005471.11353.36940609.46200-0.786407.091405.60770HepG2SERBP1
ABCB4ENSG00000005471.11421.66420848.17470-1.008309.681508.36100HepG2SF3A3
ABCB4ENSG00000005471.11760.87390420.502900.855409.447608.21990HepG2SF3B1
ABCB4ENSG00000005471.11746.095901167.86790-0.6464010.950509.89400HepG2SF3B4
ABCB4ENSG00000005471.111074.46360902.737800.251102.463801.79590HepG2SLBP
ABCB4ENSG00000005471.11590.08130814.86200-0.465602.591101.66580HepG2SMNDC1
ABCB4ENSG00000005471.11867.06210467.886200.889906.556905.34510HepG2SNRNP70
ABCB4ENSG00000005471.11545.67480896.02510-0.7155011.5861010.75060HepG2SRFBP1
ABCB4ENSG00000005471.11311.646501219.00670-1.9677074.5607072.87740HepG2SRSF1
ABCB4ENSG00000005471.111216.32050991.731500.294403.275502.68530HepG2SRSF9
ABCB4ENSG00000005471.11382.93820557.86430-0.542802.603001.39740HepG2STAU1
ABCB4ENSG00000005471.11782.907601095.70580-0.484906.122405.34360HepG2TAF15
ABCB4ENSG00000005471.11640.90650414.128900.629905.173504.22660HepG2TARDBP
ABCB4ENSG00000005471.11568.60180315.719900.848706.946805.48990HepG2TFIP11
ABCB4ENSG00000005471.11788.735001006.78840-0.352102.963802.10170HepG2TIA1
ABCB4ENSG00000005471.11418.74320673.48090-0.685607.631806.87710HepG2TIAL1
ABCB4ENSG00000005471.111351.05320919.796400.554606.740005.28310HepG2TUFM
ABCB4ENSG00000005471.11411.14110765.02190-0.895902.441201.52190HepG2U2AF2
ABCB4ENSG00000005471.11921.71910752.202300.293102.777702.07610HepG2UPF1
ABCB4ENSG00000005471.11497.93650726.22020-0.544406.225405.38590HepG2UTP3
ABCB4ENSG00000005471.11456.91460879.27390-0.944408.248506.51620HepG2XRCC6
ABCB4ENSG00000005471.11706.47210508.827600.473405.281804.40360HepG2ZC3H8
ABCB4ENSG00000005471.11573.55620827.27710-0.528407.705006.91100HepG2ZNF622
ABCB4ENSG00000005471.1133.2019010.419501.671902.223501.68800K562AQR
ABCB4ENSG00000005471.1143.8219014.829601.563102.679001.63970K562CNOT7
ABCB4ENSG00000005471.1133.8391011.577001.547302.582501.78980K562EIF4A3
ABCB4ENSG00000005471.1133.934106.709602.338303.643201.97390K562GEMIN5
ABCB4ENSG00000005471.11104.3464017.048602.6136010.646409.13600K562GRSF1
ABCB4ENSG00000005471.1141.0626011.552701.829503.882502.61220K562HNRNPA1
ABCB4ENSG00000005471.1152.188607.556302.787906.710805.82090K562HNRNPC
ABCB4ENSG00000005471.1134.3883012.789801.426802.345501.52230K562HNRNPU
ABCB4ENSG00000005471.1136.990009.776501.919602.932701.96740K562KRR1
ABCB4ENSG00000005471.1136.8085010.870701.759503.093902.24140K562MTPAP
ABCB4ENSG00000005471.1133.547606.512202.364903.410602.57590K562PRPF8
ABCB4ENSG00000005471.1159.4111024.009101.307103.063402.20580K562PUF60
ABCB4ENSG00000005471.1151.1279017.934801.511302.690301.48400K562SNRNP200
ABCB4ENSG00000005471.1132.8702012.209901.428602.146801.31330K562SRPK2
ABCB4ENSG00000005471.1151.4350013.500401.929604.991104.02630K562TARDBP
ABCB4ENSG00000005471.1157.3503011.744302.287706.782205.33550K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ABCB4 is not available on ENCORE database.





4 RBPs can affect the splicing of ABCB4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEABCB4ENSG00000005471.11chr7-870412088704134987038551870387088704293287043033-0.262000.002450.05507excludedHepG2HNRNPK
SEABCB4ENSG00000005471.11chr7-870429328704303387038551870387088704662787046831-0.169000.004230.09289excludedHepG2SF3A3
SEABCB4ENSG00000005471.11chr7-8704120887041349870385518703870887042932870430330.286000.001470.08039includedHepG2SRSF9
MXEABCB4ENSG00000005471.11chr7-87042932870430338704662787046831870412088704134987047852870479360.435000.000410.018451includedHepG2RBFOX2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ABCB4 is not avaliable on ENCORE database.