NVL

General Information

Gene Name       : NVL
Gene ID             : ENSG00000143748.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NVL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NVLENSG00000143748.1736.7129.6833.20ENCSR000AEF
HepG2NVLENSG00000143748.1710.0814.9512.52ENCSR985KAT
K562NVLENSG00000143748.1745.9749.6847.83ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NVL is not avaliable on ENCORE database.



Proteins bound to RNA
  • NVL RNA is bound by 16 proteins.  







eCLIP assay for NVL is not avaliable on ENCORE database.





16 proteins are bound to NVL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1224492809224492839-3'-UTR,5'-UTR,CDS,intron-Distal4.204877.82678K562ZNF622
chr1224492773224492875-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.687105.55543K562GPKOW
chr1224499529224499589-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.128005.65906K562AQR
chr1224499497224499529-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.051183.12081K562AQR
chr1224492705224492828-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.791457.19050K562ZNF800
chr1224482034224482103-3'-UTR,CDS,intron-Distal,intron-Proximal4.924595.70640HepG2BCLAF1
chr1224481964224482035-3'-UTR,CDS,intron-Distal,intron-Proximal4.086929.36792K562ZNF622
chr1224492725224492840-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.117413.48757K562TRA2A
chr1224492704224492847-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.5024611.86464K562BUD13
chr1224492764224492809-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.043198.70187K562ZNF622
chr1224437958224438032-3'-UTR,CDS,intron-Distal,intron-Proximal3.721993.39716K562U2AF2
chr1224499498224499575-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.902395.89850HepG2AQR
chr1224492496224492525-5'-UTR,CDS,intron-Distal,intron-Proximal3.419467.42773K562BUD13
chr1224492691224492741-5'-UTR,CDS,intron-Distal,intron-Proximal3.662635.75231K562AQR
chr1224492699224492762-5'-UTR,CDS,intron-Distal,intron-Proximal3.836306.39986K562SF3B4
chr1224492452224492516-5'-UTR,CDS,intron-Distal,intron-Proximal3.210263.92909K562GRWD1
chr1224492454224492514-5'-UTR,CDS,intron-Distal3.331594.85828HepG2BCLAF1
chr1224492688224492773-5'-UTR,CDS,intron-Distal,intron-Proximal3.933205.51636K562GPKOW
chr1224492733224492764-5'-UTR,CDS,intron-Distal,intron-Proximal4.512848.85033K562ZNF622
chr1224492444224492515-5'-UTR,CDS,intron-Distal,intron-Proximal3.304177.86771K562ZNF622
chr1224517699224517824-5'-UTR,CDS,intron-Distal,intron-Proximal4.337777.13970HepG2PRPF8
chr1224492716224492762-5'-UTR,CDS,intron-Distal,intron-Proximal3.630113.87469HepG2BCLAF1
chr1224475638224475718-CDS,intron-Distal,intron-Proximal3.236673.05068HepG2U2AF2
chr1224475641224475693-CDS,intron-Distal3.437704.13746HepG2PPIG
chr1224477189224477242-CDS,intron-Distal3.464256.41974HepG2PPIG
chr1224475640224475724-CDS,intron-Distal,intron-Proximal4.316604.90655K562U2AF2
chr1224495707224495750-CDS,intron-Distal,intron-Proximal3.617364.40383K562UCHL5
chr1224475630224475662-CDS,intron-Distal3.432603.73423K562UCHL5
chr1224477180224477248-CDS,intron-Distal,intron-Proximal4.059626.43326K562UCHL5
chr1224415336224415356-CDS,intron-Distal4.152333.77023K562ZNF622
chr1224475662224475695-CDS,intron-Distal4.794784.42734K562UCHL5
chr1224475646224475687-CDS,intron-Distal3.366434.44630K562ZNF622
chr1224463036224463091-CDS,intron-Distal,intron-Proximal3.255566.21602K562ZNF622
chr1224477191224477230-CDS,intron-Distal4.324214.46002K562DDX24
chr1224471880224471943-intron-Distal4.765047.91159K562KHSRP
chr1224475708224475806-intron-Distal,intron-Proximal3.829653.06150K562KHSRP
chr1224514173224514338-intron-Distal,intron-Proximal3.655484.72639K562KHSRP
chr1224482421224482538-intron-Distal4.267565.02888K562KHSRP
chr1224505264224505354-intron-Distal,intron-Proximal4.847436.45599K562PRPF8
chr1224452265224452428-intron-Distal3.453137.08481K562KHSRP
chr1224471965224472011-intron-Distal3.923783.42844K562KHSRP
chr1224473371224473460-intron-Distal4.578406.73684K562KHSRP
chr1224500690224500711-intron-Distal,intron-Proximal4.729449.85896K562AQR
chr1224482177224482265-intron-Distal,intron-Proximal3.535324.70224K562KHSRP
chr1224468671224468814-intron-Distal,intron-Proximal3.327804.70224K562KHSRP
chr1224461692224461761-intron-Distal3.231863.71972K562TARDBP
chr1224473185224473263-intron-Distal3.868263.25538K562KHSRP
chr1224471761224471865-intron-Distal3.467658.93789K562KHSRP
chr1224505333224505381-intron-Distal,intron-Proximal5.577078.88118K562AQR
chr1224500654224500690-intron-Distal,intron-Proximal5.622379.23760K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NVL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NVL is not available on ENCORE database.

  • 53 RBPs can affect the levels of NVL.  








The Knockdown/knockout RNA-Seq assay for NVL is not available on ENCORE database.





53 RBPs can affect the gene expression of NVL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NVLENSG00000143748.13442.49780320.455000.465402.079301.61100HepG2AKAP1
NVLENSG00000143748.13363.45710472.55970-0.378702.704402.02540HepG2AUH
NVLENSG00000143748.13350.90240262.800900.417002.004201.48770HepG2BOP1
NVLENSG00000143748.13363.15630251.908000.527602.715601.95030HepG2CIRBP
NVLENSG00000143748.13159.19150263.70730-0.728203.342602.67060HepG2DDX6
NVLENSG00000143748.13146.84390253.61680-0.788405.244804.30510HepG2DNAJC21
NVLENSG00000143748.13190.74230251.35900-0.398102.028101.45340HepG2DNAJC2
NVLENSG00000143748.13157.63900253.48910-0.685303.151502.52030HepG2EIF2S1
NVLENSG00000143748.13248.29820397.20500-0.677804.689303.64720HepG2EIF4G2
NVLENSG00000143748.13221.68230359.75460-0.698505.575804.60040HepG2HNRNPF
NVLENSG00000143748.13308.27460382.89500-0.312701.914101.34040HepG2HNRNPL
NVLENSG00000143748.13170.28540261.01750-0.616202.716102.09110HepG2HNRNPLL
NVLENSG00000143748.13231.93950354.25790-0.611103.984103.12940HepG2IGF2BP1
NVLENSG00000143748.13337.30950235.064500.520902.975702.13750HepG2MSI2
NVLENSG00000143748.13161.02170295.57790-0.876304.720503.39140HepG2PCBP2
NVLENSG00000143748.13193.07340397.85120-1.043109.902108.87110HepG2PUF60
NVLENSG00000143748.13587.36030453.490100.373102.552102.04930HepG2RBM22
NVLENSG00000143748.13304.31800381.45010-0.325901.942201.33580HepG2SLBP
NVLENSG00000143748.13560.20340292.624900.936808.445107.72120HepG2SRSF1
NVLENSG00000143748.13218.79350353.43900-0.691905.506304.58080HepG2SRSF7
NVLENSG00000143748.13204.79540274.92810-0.424901.923001.48960HepG2TIAL1
NVLENSG00000143748.13173.75000277.36140-0.674804.854604.15050HepG2TRIM56
NVLENSG00000143748.13356.62370248.421100.521502.681302.06150HepG2U2AF1
NVLENSG00000143748.131210.920901658.52690-0.453807.494806.62620K562AGGF1
NVLENSG00000143748.131285.910701725.74880-0.424404.290903.47280K562AKAP8L
NVLENSG00000143748.131189.948901697.75320-0.512705.671104.88250K562AQR
NVLENSG00000143748.131541.918501810.68140-0.231802.218801.40930K562ATP5C1
NVLENSG00000143748.13867.235801039.78360-0.261802.517301.60380K562BCLAF1
NVLENSG00000143748.13362.11820526.63850-0.540403.607602.36880K562CCAR1
NVLENSG00000143748.132506.381801448.000500.7914024.3433022.60150K562DDX47
NVLENSG00000143748.13658.59530956.43710-0.538302.460501.60130K562EFTUD2
NVLENSG00000143748.13764.39790535.694500.512802.221901.33280K562EIF3A
NVLENSG00000143748.131244.61690945.881400.395902.872402.06270K562EIF3G
NVLENSG00000143748.131127.63840796.874800.500804.829703.74310K562EIF4A3
NVLENSG00000143748.131122.35730828.713700.437505.199004.40680K562FXR1
NVLENSG00000143748.13654.75790864.99010-0.401702.988102.16360K562GPKOW
NVLENSG00000143748.131598.609001996.52380-0.320702.828002.06480K562GRSF1
NVLENSG00000143748.13560.75810829.63100-0.565105.200703.56650K562HNRNPF
NVLENSG00000143748.13980.998501308.54280-0.415604.055102.74740K562HNRNPL
NVLENSG00000143748.131558.494202051.76860-0.396704.543503.31830K562MBNL1
NVLENSG00000143748.13929.478201124.58020-0.274902.559701.78020K562MTPAP
NVLENSG00000143748.131039.986501249.48810-0.264803.187602.39090K562NSUN2
NVLENSG00000143748.13664.50650833.01780-0.326102.134601.35090K562PSIP1
NVLENSG00000143748.13907.791501131.68540-0.318002.624601.97540K562PTBP1
NVLENSG00000143748.131661.717102315.06140-0.478405.002003.90720K562PUF60
NVLENSG00000143748.131220.856201667.59360-0.449906.180605.32010K562RBM15
NVLENSG00000143748.13859.545901085.32100-0.336502.447201.66000K562RBM22
NVLENSG00000143748.131512.10810948.238200.673105.479204.32690K562RPS19
NVLENSG00000143748.13836.172801232.95780-0.560308.413707.05090K562SF3A3
NVLENSG00000143748.13624.90650822.67600-0.396702.264901.39510K562SF3B1
NVLENSG00000143748.13712.09290928.50650-0.382803.372202.42660K562SF3B4
NVLENSG00000143748.131474.828101109.394100.410704.231503.36510K562SRSF1
NVLENSG00000143748.131259.45130918.492900.455403.825402.85860K562SYNCRIP
NVLENSG00000143748.13810.429301122.85440-0.470404.004403.14570K562TARDBP
NVLENSG00000143748.13556.22530801.23260-0.526603.830402.72270K562TIAL1
NVLENSG00000143748.13622.68200851.12540-0.450903.592002.48840K562TRIM56
NVLENSG00000143748.13689.40530893.88620-0.374703.168202.30950K562U2AF2
NVLENSG00000143748.13955.338201735.25190-0.861105.431303.43200K562UTP18
NVLENSG00000143748.131444.872801178.871500.293403.814802.83200K562WDR43
NVLENSG00000143748.131587.050501912.66050-0.269202.095101.35440K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NVL is not available on ENCORE database.





20 RBPs can affect the splicing of NVL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENVLENSG00000143748.13chr1-224500751224500853224499501224499559224505395224505495-0.175000.000260.00701excludedK562SRSF1
SENVLENSG00000143748.13chr1-224454705224454925224437913224438020224455735224455835-0.120000.000240.00653excludedK562SRSF1
SENVLENSG00000143748.13chr1-2244547052244549252244379132244380202244557352244558350.281000.000590.09675includedK562FTO
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.265000.000000.00020excludedK562SF3B4
SENVLENSG00000143748.13chr1-224499501224499559224495884224495965224505395224505495-0.163000.006260.08803excludedK562SF3B4
SENVLENSG00000143748.13chr1-224499501224499559224495692224495965224505395224505495-0.121000.001400.04096excludedK562AKAP8L
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.173000.000090.03299excludedK562WDR43
SENVLENSG00000143748.13chr1-2244547052244549252244379132244380202244557352244558350.188000.000720.00922includedK562AQR
SENVLENSG00000143748.13chr1-224499501224499559224495694224495965224505395224505495-0.153000.000820.01039excludedK562AQR
SENVLENSG00000143748.13chr1-224455735224455835224437913224438020224463040224463160-0.086000.000630.00829excludedK562AQR
SENVLENSG00000143748.13chr1-224514092224514166224505589224505632224517772224517870-0.286000.000000.00000excludedK562AQR
SENVLENSG00000143748.13chr1-224454705224454925224437913224438020224455735224455835-0.123000.000520.02331excludedK562FXR1
SENVLENSG00000143748.13chr1-224499501224499559224495884224495965224505395224505495-0.162000.000060.00156excludedK562PUS1
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.237000.000000.00030excludedK562MTPAP
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.371000.000000.00000excludedK562U2AF1
SENVLENSG00000143748.13chr1-224499501224499559224495884224495965224505395224505495-0.150000.000820.05537excludedK562HNRNPL
SENVLENSG00000143748.13chr1-224514092224514155224505579224505632224517772224517840-0.227000.000660.04909excludedK562HNRNPUL1
SENVLENSG00000143748.13chr1-224492437224492514224491424224491559224492735224492868-0.160000.000160.00836excludedK562UTP18
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.246000.000160.00849excludedK562UTP18
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.146000.000370.06378excludedK562UPF1
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.134000.003680.07384excludedK562AGGF1
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.135000.000280.04540excludedK562ZC3H8
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.141000.000640.03202excludedK562HNRNPK
SENVLENSG00000143748.13chr1-224454705224454925224437913224438020224455735224455835-0.179000.000500.09073excludedK562SAFB
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.258000.000000.00001excludedK562PTBP1
SENVLENSG00000143748.13chr1-2244893922244894732244882632244883652244914242244915590.493000.000000.00000includedK562HNRNPC
SENVLENSG00000143748.13chr1-224514092224514166224505579224505632224517772224517850-0.404000.000000.00004excludedK562HNRNPC
A3SSNVLENSG00000143748.13chr1-2244914242244916222244914242244915592244924372244925140.153000.000000.00000longerK562AQR
MXENVLENSG00000143748.13chr1-224488263224488365224491424224491559224481968224482113224492437224492514-0.112000.000930.008622includedK562AQR
MXENVLENSG00000143748.13chr1-224491424224491585224492437224492514224488263224488365224492735224492868-0.134000.003690.027872includedK562AQR
MXENVLENSG00000143748.13chr1-224491424224491559224492437224492514224488263224488365224492735224492868-0.134000.003300.025412includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NVL is not avaliable on ENCORE database.