ADAM10

General Information

Gene Name : ADAM10
Gene ID : ENSG00000137845.14
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: ADAM10)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ADAM10	ENSG00000137845.14	37.98	40.52	39.25	ENCSR000AEF
HepG2	ADAM10	ENSG00000137845.14	73.53	87.40	80.47	ENCSR985KAT
K562	ADAM10	ENSG00000137845.14	45.38	38.56	41.97	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ADAM10 is not avaliable on ENCORE database.

Proteins bound to RNA

ADAM10 RNA is bound by 42 proteins.

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eCLIP assay for ADAM10 is not avaliable on ENCORE database.

42 proteins are bound to ADAM10 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr15	59041786	59041867	-	5'-UTR,intron-Distal,intron-Proximal	4.55735	400.00000	HepG2	DDX3X
chr15	58932988	58933032	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.71880	48.36746	K562	LIN28B
chr15	58932974	58932988	-	5'-UTR,CDS,intron-Distal,intron-Proximal	6.14477	43.24770	K562	LIN28B
chr15	59041867	59041940	-	5'-UTR,intron-Distal,intron-Proximal	3.51539	43.12992	HepG2	DDX3X
chr15	58932974	58933024	-	5'-UTR,CDS,intron-Distal,intron-Proximal	6.15810	39.25408	HepG2	LIN28B
chr15	59041728	59041786	-	5'-UTR,CDS,intron-Distal	4.42398	37.25225	HepG2	DDX3X
chr15	59041675	59041714	-	CDS,intron-Distal	4.65871	35.70954	HepG2	DDX3X
chr15	58968086	58968210	-	intron-Distal	6.74132	34.13137	K562	KHSRP
chr15	58889234	58889335	-	3'-UTR,intron-Distal,intron-Proximal	3.52468	23.38984	K562	PUM2
chr15	58887861	58887922	-	3'-UTR,intron-Distal	4.86021	23.31949	HepG2	FUBP3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 203 entries

eCLIP assay for ADAM10 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for ADAM10 is not available on ENCORE database.
117 RBPs can affect the levels of ADAM10.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for ADAM10 is not available on ENCORE database.

117 RBPs can affect the gene expression of ADAM10 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ADAM10	ENSG00000137845.10	1507.17230	3442.04950	-1.19140	50.24460	47.79560	HepG2	DNAJC21
ADAM10	ENSG00000137845.10	1620.03730	3731.11310	-1.20360	43.61360	42.07080	HepG2	TIAL1
ADAM10	ENSG00000137845.10	3117.33370	5264.04060	-0.75590	33.14930	31.64830	HepG2	SRSF9
ADAM10	ENSG00000137845.10	1330.87970	2942.49550	-1.14470	32.23690	29.74920	HepG2	HNRNPM
ADAM10	ENSG00000137845.10	1190.88300	2504.71160	-1.07260	30.40390	26.95750	HepG2	FAM120A
ADAM10	ENSG00000137845.10	672.89770	1538.44360	-1.19300	26.51800	24.75050	K562	HNRNPC
ADAM10	ENSG00000137845.10	1971.39430	3865.30060	-0.97140	22.52300	20.75310	HepG2	HNRNPC
ADAM10	ENSG00000137845.10	4431.26450	6626.37330	-0.58050	19.41310	18.23240	HepG2	NELFE
ADAM10	ENSG00000137845.10	1499.50870	2514.02430	-0.74550	19.51200	18.01880	K562	FXR1
ADAM10	ENSG00000137845.10	3304.02340	6531.78930	-0.98330	18.00110	16.40360	HepG2	MAGOH
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 135 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ADAM10 is not available on ENCORE database.

4 RBPs can affect the splicing of ADAM10 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	ADAM10	ENSG00000137845.10	chr15	-	58891796	58891982	58891796	58891923	58902495	58902716	0.20600	0.00000	0.00000	longer	K562	AQR
A3SS	ADAM10	ENSG00000137845.10	chr15	-	58902495	58902741	58902495	58902716	58903197	58903340	0.08600	0.00000	0.00001	longer	K562	AQR
A3SS	ADAM10	ENSG00000137845.10	chr15	-	58957350	58957423	58957350	58957396	58971322	58971481	0.08000	0.00001	0.00015	longer	K562	AQR
SE	ADAM10	ENSG00000137845.10	chr15	-	58936084	58936177	58932975	58933159	58938253	58938403	-0.11800	0.00024	0.01150	excluded	K562	UTP18
SE	ADAM10	ENSG00000137845.10	chr15	-	58936084	58936177	58932975	58933159	58938253	58938403	-0.10800	0.00033	0.00473	excluded	K562	AQR
SE	ADAM10	ENSG00000137845.10	chr15	-	58936084	58936177	58932975	58933159	58938253	58938403	-0.10900	0.00070	0.02085	excluded	K562	AGGF1
SE	ADAM10	ENSG00000137845.10	chr15	-	58936084	58936177	58932975	58933159	58938253	58938403	-0.10900	0.00085	0.02417	excluded	K562	RBM15
SE	ADAM10	ENSG00000137845.10	chr15	-	58925394	58925558	58919898	58920082	58932975	58933029	-0.05100	0.00140	0.01617	excluded	K562	AQR

Showing 1 to 8 of 8 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ADAM10

General Information

Functions

Localization

Domains (AlphaFold: ADAM10)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ADAM10 is not avaliable on ENCORE database.

42 proteins are bound to ADAM10 RNA:

eCLIP assay for ADAM10 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for ADAM10 is not available on ENCORE database.

117 RBPs can affect the gene expression of ADAM10 :

The Knockdown/knockout RNA-Seq assay for ADAM10 is not available on ENCORE database.

4 RBPs can affect the splicing of ADAM10 :

The Knockdown/knockout RNA-Seq assay for ADAM10 is not avaliable on ENCORE database.