COA4

General Information

Gene Name       : COA4
Gene ID             : ENSG00000181924.6
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: COA4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COA4ENSG00000181924.637.9565.6251.79ENCSR000AEF
HepG2COA4ENSG00000181924.6101.2764.6482.95ENCSR985KAT
K562COA4ENSG00000181924.6150.48108.00129.24ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COA4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COA4 RNA is bound by 11 proteins.  







eCLIP assay for COA4 is not avaliable on ENCORE database.





11 proteins are bound to COA4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr117358411273584178-3'-UTR,CDS,intron-Distal4.366025.60746K562YBX3
chr117358399473584069-3'-UTR,intron-Distal,intron-Proximal3.465473.54552HepG2LARP4
chr117358373573583835-3'-UTR,intron-Distal,intron-Proximal4.5910019.53911HepG2ZC3H11A
chr117358435073584462-3'-UTR,CDS,intron-Distal3.478663.39008HepG2AQR
chr117358428473584429-3'-UTR,CDS,intron-Distal3.756355.11568K562PUM1
chr117358375673583827-3'-UTR,intron-Distal,intron-Proximal5.2036127.15095K562ZC3H11A
chr117358780173587919-5'-UTR,intron-Distal,intron-Proximal3.777658.98176K562DDX3X
chr117358757273587650-5'-UTR,intron-Distal,intron-Proximal4.489356.32636HepG2U2AF2
chr117358768673587753-5'-UTR,intron-Distal,intron-Proximal3.487836.81166HepG2XPO5
chr117358773573587833-5'-UTR,intron-Distal,intron-Proximal3.534105.73990HepG2PRPF8
chr117358428973584405-CDS,intron-Distal4.812957.65454HepG2SRSF1
chr117358426273584360-CDS,intron-Distal4.8891115.54543HepG2GRWD1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COA4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COA4 is not available on ENCORE database.

  • 79 RBPs can affect the levels of COA4.  








The Knockdown/knockout RNA-Seq assay for COA4 is not available on ENCORE database.





79 RBPs can affect the gene expression of COA4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COA4ENSG00000181924.6780.157001217.17860-0.6417011.6492010.40710HepG2AUH
COA4ENSG00000181924.6871.30780637.074200.451602.183601.35400HepG2BCCIP
COA4ENSG00000181924.6715.11950493.545100.534905.699204.23900HepG2YBX3
COA4ENSG00000181924.61181.96290953.517600.309802.549301.83230HepG2DAZAP1
COA4ENSG00000181924.6902.443001264.34480-0.486503.871703.14270HepG2DDX3X
COA4ENSG00000181924.6701.40550484.580600.533405.689504.71140HepG2DNAJC21
COA4ENSG00000181924.6684.47290480.365100.510806.405805.47280HepG2DNAJC2
COA4ENSG00000181924.61636.564701153.757200.504203.910703.15460HepG2EIF4A3
COA4ENSG00000181924.61093.990301397.57630-0.353304.349503.62550HepG2ETF1
COA4ENSG00000181924.6530.36670840.35150-0.664004.985203.98000HepG2FIP1L1
COA4ENSG00000181924.6654.51480489.223700.419802.843502.18790HepG2HNRNPA1
COA4ENSG00000181924.6883.45840544.192000.698907.382506.29330HepG2HNRNPC
COA4ENSG00000181924.61127.12520868.507500.375905.220904.31980HepG2HNRNPL
COA4ENSG00000181924.6675.51580540.592600.321302.673702.07750HepG2HNRNPU
COA4ENSG00000181924.6721.13270552.193800.385004.210403.32470HepG2ILF2
COA4ENSG00000181924.6716.09770942.65350-0.396602.106101.38950HepG2LARP4
COA4ENSG00000181924.61741.359901171.227200.572104.971904.14720HepG2MATR3
COA4ENSG00000181924.61137.19760945.519200.266202.527701.80000HepG2NOL12
COA4ENSG00000181924.6366.83130575.40390-0.649503.147701.97770HepG2NONO
COA4ENSG00000181924.6672.32850482.161700.479504.678903.74670HepG2PPIL4
COA4ENSG00000181924.6731.734901102.32200-0.591208.774907.91180HepG2PTBP1
COA4ENSG00000181924.6867.199801083.47130-0.321202.443801.80650HepG2RBM25
COA4ENSG00000181924.61033.92350748.221800.466503.254602.17350HepG2RBM27
COA4ENSG00000181924.6817.50700607.590800.428002.570101.54880HepG2RCC2
COA4ENSG00000181924.6881.104501226.76610-0.477506.520405.74920HepG2NELFE
COA4ENSG00000181924.6859.063101142.58860-0.411505.021204.22120HepG2RECQL
COA4ENSG00000181924.6743.19400555.026400.421102.105301.40690HepG2RPS3A
COA4ENSG00000181924.61029.97050704.402000.548004.413603.04080HepG2RPS5
COA4ENSG00000181924.6805.15340481.409200.7419012.6202011.39430HepG2SAFB2
COA4ENSG00000181924.6756.06300588.344400.361702.344501.69240HepG2SF3B1
COA4ENSG00000181924.6969.821701147.63250-0.242902.068001.54550HepG2SF3B4
COA4ENSG00000181924.6717.16140561.383600.353203.516802.80600HepG2SMN1
COA4ENSG00000181924.6762.84070535.083700.511502.983601.98540HepG2SMNDC1
COA4ENSG00000181924.61155.547101319.28730-0.191201.732801.30760HepG2SRFBP1
COA4ENSG00000181924.61438.240301145.394200.328404.044103.44920HepG2SSB
COA4ENSG00000181924.61223.215801013.605100.271102.883402.25130HepG2SUCLG1
COA4ENSG00000181924.6680.755901076.74170-0.661508.149007.26890HepG2TAF15
COA4ENSG00000181924.6805.95960989.34640-0.295802.196401.44920HepG2TIA1
COA4ENSG00000181924.6768.86920525.207700.549805.621104.95770HepG2TIAL1
COA4ENSG00000181924.6728.70990529.987500.459304.998704.28570HepG2TRIM56
COA4ENSG00000181924.6578.77600718.79650-0.312601.846001.32170HepG2U2AF1
COA4ENSG00000181924.6498.10860368.295700.435502.157201.48700HepG2UCHL5
COA4ENSG00000181924.6988.21090656.268200.590408.950307.97310HepG2UTP3
COA4ENSG00000181924.6957.33340613.795300.641204.854103.90260HepG2XRN2
COA4ENSG00000181924.6996.331001753.53560-0.815604.834304.09760K562AQR
COA4ENSG00000181924.6510.36400788.47510-0.627505.420704.18760K562BOP1
COA4ENSG00000181924.6900.108501285.29090-0.513902.569001.55280K562CNOT7
COA4ENSG00000181924.6488.35910838.39410-0.779709.984908.48370K562CPSF6
COA4ENSG00000181924.61252.976301005.378500.317503.055501.65900K562DDX27
COA4ENSG00000181924.61791.849701269.602500.497009.160408.05880K562DDX47
COA4ENSG00000181924.61216.108101574.68010-0.372804.799603.88620K562EIF2S2
COA4ENSG00000181924.6848.74650539.994400.652308.203206.83880K562EIF3G
COA4ENSG00000181924.61625.357702004.74930-0.302703.469202.42050K562EIF4G2
COA4ENSG00000181924.6507.33700853.00960-0.749608.047306.54100K562FMR1
COA4ENSG00000181924.6475.87930722.98670-0.603404.815303.57630K562FTO
COA4ENSG00000181924.61291.77040663.637300.9608021.8932020.30650K562FXR1
COA4ENSG00000181924.6566.50970800.47510-0.498802.628201.85170K562GPKOW
COA4ENSG00000181924.6651.67540979.16130-0.587403.848203.15850K562HNRNPC
COA4ENSG00000181924.6539.23980874.18790-0.697005.213703.57680K562HNRNPF
COA4ENSG00000181924.61222.83490854.840900.516404.106602.95680K562HNRNPM
COA4ENSG00000181924.61185.449001419.65010-0.260102.206001.40980K562HNRNPU
COA4ENSG00000181924.6442.75460683.46640-0.626403.921502.79460K562KRR1
COA4ENSG00000181924.6856.30730696.872000.297102.081601.34720K562MAGOH
COA4ENSG00000181924.6987.51590695.431800.505805.306603.97320K562MATR3
COA4ENSG00000181924.6602.90390781.34670-0.374002.657101.80250K562METAP2
COA4ENSG00000181924.6973.911901185.03010-0.283103.568802.73190K562NSUN2
COA4ENSG00000181924.6750.143501138.36480-0.601705.243804.09550K562PCBP3
COA4ENSG00000181924.6660.38130873.14710-0.402903.384802.49230K562POLR2G
COA4ENSG00000181924.61544.882901179.813500.388803.195102.30330K562PPIG
COA4ENSG00000181924.61067.68740677.067800.657008.830907.68590K562PTBP1
COA4ENSG00000181924.61093.51470858.512000.349002.135401.42230K562RPS19
COA4ENSG00000181924.61071.37560778.050000.461404.313902.95100K562SAFB
COA4ENSG00000181924.6528.11260761.22530-0.527503.551302.44420K562SF3B1
COA4ENSG00000181924.61023.409001197.87940-0.227102.305101.44270K562SRPK2
COA4ENSG00000181924.6894.31970663.771700.430003.682102.87180K562SRSF1
COA4ENSG00000181924.6813.460201016.16910-0.321002.833201.64770K562SRSF7
COA4ENSG00000181924.6555.76690949.82870-0.773203.186901.62260K562SUPT6H
COA4ENSG00000181924.6608.15250816.04450-0.424202.564601.59050K562SUPV3L1
COA4ENSG00000181924.61127.10880875.813500.363803.293802.39900K562SYNCRIP
COA4ENSG00000181924.6234.21970386.99840-0.724503.107001.52840K562TAF15
COA4ENSG00000181924.6272.29370410.91590-0.593703.414601.62910K562TBRG4
COA4ENSG00000181924.6645.67260863.67420-0.419702.839401.80400K562UCHL5
COA4ENSG00000181924.6953.607901256.50700-0.398004.820603.90020K562UPF1
COA4ENSG00000181924.6776.574401075.16250-0.469404.783503.61710K562WDR3
COA4ENSG00000181924.61381.269701117.981800.305003.842202.85580K562WDR43
COA4ENSG00000181924.61381.139401975.72940-0.516502.863101.98270K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COA4 is not available on ENCORE database.





12 RBPs can affect the splicing of COA4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.133000.000270.05930includedK562FTO
SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.095000.000000.00001includedK562XRCC6
SECOA4ENSG00000181924.6chr11-735875237358762073584041735844397358780173587888-0.079000.000120.01738excludedHepG2SRSF7
SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.070000.000000.00008includedK562SUPV3L1
SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.126000.000040.01472includedK562GPKOW
SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.095000.000240.02258includedHepG2TIAL1
SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.127000.000080.01472includedK562CPSF6
SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.113000.000540.09966includedHepG2EIF3D
SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.065000.000010.00092includedHepG2SRSF9
SECOA4ENSG00000181924.6chr11-735875237358762073584041735844397358780173587888-0.091000.000400.07715excludedHepG2PRPF4
SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.147000.000000.00000includedK562HNRNPC
A3SSCOA4ENSG00000181924.6chr11-7358743673587679735874367358762073587801735878880.184000.000570.00417longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COA4 is not avaliable on ENCORE database.