LEPROT

General Information

Gene Name       : LEPROT
Gene ID             : ENSG00000213625.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LEPROT)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LEPROTENSG00000213625.812.7111.8912.30ENCSR000AEF
HepG2LEPROTENSG00000213625.816.6526.2521.45ENCSR985KAT
K562LEPROTENSG00000213625.831.7731.9131.84ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LEPROT is not avaliable on ENCORE database.



Proteins bound to RNA
  • LEPROT RNA is bound by 23 proteins.  







eCLIP assay for LEPROT is not avaliable on ENCORE database.





23 proteins are bound to LEPROT RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr16589861565898684+3'-UTR,intron-Distal5.5602611.83696HepG2UPF1
chr16589864765898756+3'-UTR,intron-Distal3.214134.57410HepG2IGF2BP3
chr16590068965900759+3'-UTR,intron-Distal4.380617.64390K562RBM15
chr16589913165899190+3'-UTR,intron-Distal3.937693.09815K562IGF2BP1
chr16589881665898908+3'-UTR,intron-Distal4.006993.77064HepG2IGF2BP3
chr16589763165897676+3'-UTR,intron-Distal3.002903.03131K562HNRNPL
chr16590156765901682+3'-UTR,intron-Distal3.842193.01017K562CPSF6
chr16589881265898874+3'-UTR,intron-Distal3.337307.35607HepG2UPF1
chr16589870065898757+3'-UTR,intron-Distal3.100814.39754HepG2FAM120A
chr16589899365899091+3'-UTR,intron-Distal3.792943.57062K562IGF2BP1
chr16589868465898778+3'-UTR,intron-Distal4.6107315.14578HepG2UPF1
chr16588638465886481+5'-UTR,CDS,intron-Proximal4.3237612.28861HepG2PRPF8
chr16588639365886426+5'-UTR,CDS,intron-Proximal3.249407.60655K562DDX3X
chr16588627365886393+5'-UTR4.0823811.03053K562DDX3X
chr16588629665886416+5'-UTR,CDS6.2164611.20892HepG2DDX3X
chr16589102765891143+5'-UTR,CDS,intron-Proximal3.448085.20150K562GPKOW
chr16589748365897530+CDS,intron-Distal,intron-Proximal3.215226.16530HepG2SND1
chr16589745865897536+CDS,intron-Distal,intron-Proximal3.5858512.33018K562AQR
chr16589103165891180+5'-UTR,CDS,intron-Distal,intron-Proximal3.5023814.89739K562EFTUD2
chr16589102765891113+5'-UTR,CDS,intron-Proximal4.1417216.03913K562PRPF8
chr16589747565897520+CDS,intron-Distal,intron-Proximal3.718963.45592K562NCBP2
chr16589098565891030+5'-UTR,CDS,intron-Proximal3.893283.53770HepG2DDX3X
chr16588640965886472+5'-UTR,CDS,intron-Proximal3.640384.76426K562PRPF8
chr16588642265886435+5'-UTR,CDS,intron-Proximal4.7290813.38267K562AQR
chr16589747365897543+CDS,intron-Distal,intron-Proximal3.579889.77227HepG2U2AF2
chr16589102665891103+5'-UTR,CDS,intron-Proximal3.504594.46749K562RBM15
chr16589098465891024+5'-UTR,CDS,intron-Proximal3.441139.11929K562DDX3X
chr16589099665891101+5'-UTR,CDS,intron-Proximal3.7358710.48654HepG2PRPF8
chr16589747265897535+CDS,intron-Distal,intron-Proximal3.669786.73042K562U2AF1
chr16589106065891103+5'-UTR,CDS,intron-Proximal5.4485823.36607K562AQR
chr16589567365895733+CDS,intron-Distal,intron-Proximal3.321233.68647K562SND1
chr16589102565891088+5'-UTR,CDS,intron-Proximal3.870485.97159K562SRSF1
chr16589746965897534+CDS,intron-Distal,intron-Proximal3.3960312.03295K562BUD13
chr16589408165894136+intron-Distal3.703414.59821K562ILF3
chr16589575365895777+intron-Distal,intron-Proximal5.033188.11176K562TIA1
chr16589109265891198+intron-Distal,intron-Proximal3.995405.42009HepG2EFTUD2
chr16589577765895813+intron-Distal,intron-Proximal4.3901410.65642K562TIA1
chr16589596465896021+intron-Distal4.059375.44125K562PTBP1
chr16589108865891164+intron-Distal,intron-Proximal3.787537.06101K562RBM22
chr16589111365891168+intron-Distal,intron-Proximal3.9917315.43999K562AQR
chr16589110365891113+intron-Proximal4.8961713.90015K562AQR
chr16589742665897470+intron-Distal,intron-Proximal3.811917.62845K562SF3B4
chr16588643565886466+intron-Proximal4.1426114.76150K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LEPROT is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LEPROT is not available on ENCORE database.

  • 114 RBPs can affect the levels of LEPROT.  








The Knockdown/knockout RNA-Seq assay for LEPROT is not available on ENCORE database.





114 RBPs can affect the gene expression of LEPROT :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LEPROTENSG00000213625.41352.018101887.96990-0.481703.930102.82140HepG2ABCF1
LEPROTENSG00000213625.41932.146901591.192700.280003.940303.23850HepG2ACO1
LEPROTENSG00000213625.42653.260903552.38540-0.421003.188802.62240HepG2AKAP1
LEPROTENSG00000213625.41867.381501598.639200.224102.399201.67920HepG2AKAP8L
LEPROTENSG00000213625.42141.774102939.32200-0.456704.273103.30590HepG2ASCC1
LEPROTENSG00000213625.41828.331701283.680800.510104.756103.60550HepG2BCLAF1
LEPROTENSG00000213625.4882.472201228.40690-0.477204.424703.68890HepG2BOP1
LEPROTENSG00000213625.41048.399001618.20080-0.626209.475808.17220HepG2CALR
LEPROTENSG00000213625.41860.501301590.811500.225802.898802.22190HepG2CKAP4
LEPROTENSG00000213625.41666.657901127.749900.563406.192505.19510HepG2CPSF6
LEPROTENSG00000213625.41172.505701433.51070-0.290002.858801.82300HepG2YBX3
LEPROTENSG00000213625.43131.059002127.532400.5574012.8097011.62360HepG2CELF1
LEPROTENSG00000213625.41260.881801471.60900-0.223002.516801.71820HepG2DDX19B
LEPROTENSG00000213625.41868.679801280.641100.545102.750901.77470HepG2DDX59
LEPROTENSG00000213625.42206.595102923.10700-0.405702.953102.31700HepG2DDX6
LEPROTENSG00000213625.41790.859701522.331100.234302.510201.86020HepG2DKC1
LEPROTENSG00000213625.41801.417601407.696800.355704.547603.66370HepG2DNAJC21
LEPROTENSG00000213625.41891.961103023.64820-0.676405.852304.87720HepG2EIF4B
LEPROTENSG00000213625.41856.686202256.88000-0.281602.504201.69990HepG2EIF4G1
LEPROTENSG00000213625.42022.870501554.848200.379504.017103.01200HepG2EWSR1
LEPROTENSG00000213625.41743.928801382.967900.334502.936601.76180HepG2FASTKD2
LEPROTENSG00000213625.41937.547401503.620300.365703.779202.86850HepG2FUBP3
LEPROTENSG00000213625.41922.563403133.27340-0.704609.353408.15090HepG2FXR1
LEPROTENSG00000213625.42076.940102906.65310-0.484904.318103.49600HepG2G3BP1
LEPROTENSG00000213625.41285.864801740.03080-0.436402.445901.39890HepG2GRSF1
LEPROTENSG00000213625.42687.863501884.971400.511802.657301.32160HepG2HLTF
LEPROTENSG00000213625.41990.138901421.181300.485703.484602.76980HepG2HNRNPA1
LEPROTENSG00000213625.42435.851502102.397900.212302.386901.51070HepG2HNRNPA2B1
LEPROTENSG00000213625.41885.668902943.05690-0.642208.977807.77590HepG2HNRNPK
LEPROTENSG00000213625.41680.173502083.87410-0.310705.345004.43450HepG2HNRNPL
LEPROTENSG00000213625.42572.553001220.006401.0762020.6366019.16780HepG2HNRNPLL
LEPROTENSG00000213625.41029.812301315.40540-0.353103.034702.04080HepG2HNRNPM
LEPROTENSG00000213625.4778.027401570.30730-1.0132030.5694028.74110HepG2HNRNPU
LEPROTENSG00000213625.41142.534302954.57870-1.3707031.0764029.12850HepG2IGF2BP2
LEPROTENSG00000213625.42322.315303134.36660-0.432603.803303.03410HepG2MAGOH
LEPROTENSG00000213625.42383.097603151.93480-0.403403.060002.39950HepG2MATR3
LEPROTENSG00000213625.41520.005102268.42030-0.5776010.438808.99140HepG2NOL12
LEPROTENSG00000213625.42339.636302728.91630-0.222002.857102.24370HepG2PCBP1
LEPROTENSG00000213625.42211.561702776.71020-0.328305.348104.63930HepG2PTBP1
LEPROTENSG00000213625.42819.870802296.985100.295803.220302.49660HepG2PUM2
LEPROTENSG00000213625.42137.775701620.727800.399407.586706.64990HepG2PUS1
LEPROTENSG00000213625.41945.585803007.38230-0.6283013.5249012.29430HepG2QKI
LEPROTENSG00000213625.41018.498001797.31450-0.819405.583004.60230HepG2RAVER1
LEPROTENSG00000213625.42215.379501812.434900.289502.845501.97750HepG2RBM15
LEPROTENSG00000213625.43375.127102136.140700.6598010.615309.74520HepG2RBM22
LEPROTENSG00000213625.43566.249702729.341200.385804.611003.75920HepG2RBM25
LEPROTENSG00000213625.41807.248203090.26520-0.7739025.4695024.15970HepG2NELFE
LEPROTENSG00000213625.41118.729502878.06540-1.3632069.7050067.49890HepG2RECQL
LEPROTENSG00000213625.41662.250001108.532900.584405.495504.42270HepG2RRP9
LEPROTENSG00000213625.41643.972501398.455600.233302.722002.08100HepG2SAFB2
LEPROTENSG00000213625.41889.733001207.574000.646008.332307.16990HepG2SF3B1
LEPROTENSG00000213625.42532.823502891.02870-0.190802.279901.73610HepG2SF3B4
LEPROTENSG00000213625.41292.672601630.88190-0.335305.549204.68920HepG2SMN1
LEPROTENSG00000213625.41860.894501343.634700.469802.607601.84990HepG2SNRNP70
LEPROTENSG00000213625.42452.056903017.56110-0.299405.260104.66130HepG2SRSF1
LEPROTENSG00000213625.41955.896101497.125200.385506.022605.05870HepG2SRSF7
LEPROTENSG00000213625.41163.388002431.51110-1.0635048.5028046.47550HepG2SUCLG1
LEPROTENSG00000213625.41575.997201287.384900.291702.492001.59700HepG2SUPT6H
LEPROTENSG00000213625.41770.226501445.903400.291901.898601.32430HepG2SUPV3L1
LEPROTENSG00000213625.42091.255602712.17150-0.375105.810405.04940HepG2TAF15
LEPROTENSG00000213625.41880.603301189.088600.661207.936706.79150HepG2TARDBP
LEPROTENSG00000213625.41127.334301840.45740-0.707103.319702.15410HepG2TBRG4
LEPROTENSG00000213625.41276.95760969.172900.397802.788301.78930HepG2TFIP11
LEPROTENSG00000213625.41299.443401526.02190-0.231901.819901.39670HepG2TIAL1
LEPROTENSG00000213625.42307.573401630.869800.500605.176804.33280HepG2U2AF1
LEPROTENSG00000213625.4583.62480854.17840-0.549504.230403.29100HepG2UCHL5
LEPROTENSG00000213625.41096.476001594.61130-0.5403010.233709.19770HepG2UTP3
LEPROTENSG00000213625.41475.304001976.44960-0.421902.440301.44630HepG2XRCC6
LEPROTENSG00000213625.41107.816401423.33160-0.361602.208601.55460HepG2XRN2
LEPROTENSG00000213625.41615.314501257.164700.361505.896904.97280HepG2ZC3H8
LEPROTENSG00000213625.43027.982901816.507300.7371031.7352030.40180HepG2ZNF622
LEPROTENSG00000213625.41072.698901480.08940-0.464404.769403.16760K562AARS
LEPROTENSG00000213625.44575.490302770.797900.7235027.4462025.77090K562AGGF1
LEPROTENSG00000213625.44284.304903044.737400.492602.703601.73650K562AKAP8
LEPROTENSG00000213625.44531.645202883.152900.652309.030507.77140K562AKAP8L
LEPROTENSG00000213625.42220.260602915.48580-0.393004.614202.94780K562APOBEC3C
LEPROTENSG00000213625.41944.235302783.75380-0.517803.649502.99400K562AQR
LEPROTENSG00000213625.43645.896403025.144400.269203.099702.12930K562ATP5C1
LEPROTENSG00000213625.43833.467202011.911100.930006.986205.24460K562CNOT7
LEPROTENSG00000213625.46540.495404063.238700.6867016.4375014.23760K562CELF1
LEPROTENSG00000213625.42050.170902651.21850-0.370906.416005.48130K562DDX47
LEPROTENSG00000213625.41387.380601883.15010-0.440806.759105.70830K562EIF2S2
LEPROTENSG00000213625.4470.35290903.51050-0.941806.904405.26240K562EIF3A
LEPROTENSG00000213625.41233.121201638.81000-0.410305.275104.19200K562EIF3G
LEPROTENSG00000213625.41166.777902004.07140-0.780405.092603.97680K562EIF4A3
LEPROTENSG00000213625.42359.512201825.830700.369803.486202.52550K562FIP1L1
LEPROTENSG00000213625.41805.026501456.595200.309302.111701.31860K562FTO
LEPROTENSG00000213625.41954.966801448.827100.432205.552503.58200K562FUS
LEPROTENSG00000213625.41402.918302084.17140-0.571003.461402.79560K562FXR1
LEPROTENSG00000213625.42941.412402063.814600.511103.039402.29230K562G3BP2
LEPROTENSG00000213625.42564.684401620.399000.6623014.7546012.45190K562GLRX3
LEPROTENSG00000213625.42023.879402509.57660-0.310302.966302.18450K562GRSF1
LEPROTENSG00000213625.42686.402502061.882400.381603.198202.04170K562HNRNPA1
LEPROTENSG00000213625.43929.678501753.430801.164104.899803.13300K562HNRNPA2B1
LEPROTENSG00000213625.41091.639101619.28260-0.568907.405206.47450K562HNRNPC
LEPROTENSG00000213625.41047.847301501.82570-0.519304.355803.17160K562HNRNPM
LEPROTENSG00000213625.41775.595802283.15190-0.362702.352301.52800K562HNRNPU
LEPROTENSG00000213625.41991.780602475.36330-0.313602.596201.82370K562HSPD1
LEPROTENSG00000213625.41340.95490928.019700.530904.793902.84530K562ILF3
LEPROTENSG00000213625.41183.30680896.844700.399802.930501.40320K562KHDRBS1
LEPROTENSG00000213625.44521.455403059.703400.563305.244904.03440K562KIF1C
LEPROTENSG00000213625.41615.721602470.33000-0.612509.437307.82630K562MAGOH
LEPROTENSG00000213625.44935.664603521.861900.486805.971404.32620K562MSI2
LEPROTENSG00000213625.42220.478301703.638800.382205.654204.52470K562MTPAP
LEPROTENSG00000213625.43604.642602402.535700.585203.626602.58340K562NAA15
LEPROTENSG00000213625.42844.131301892.892500.5873021.9122020.10740K562NSUN2
LEPROTENSG00000213625.43140.385701532.591201.034903.376302.25020K562PABPN1
LEPROTENSG00000213625.41615.412002198.13400-0.444404.892203.58150K562PCBP2
LEPROTENSG00000213625.4961.724801412.54350-0.554605.443704.38820K562PRPF8
LEPROTENSG00000213625.41932.236302400.01800-0.312803.147502.44390K562PTBP1
LEPROTENSG00000213625.42541.606303605.06000-0.504306.549905.29380K562PUF60
LEPROTENSG00000213625.44090.436002859.210100.516506.610705.81300K562PUS1
LEPROTENSG00000213625.44216.501502785.941200.5978010.919609.76360K562RBM15
LEPROTENSG00000213625.41650.031602301.78570-0.480304.382103.29170K562RBM22
LEPROTENSG00000213625.42501.700301957.027400.354103.752402.17040K562RBM25
LEPROTENSG00000213625.41574.651002094.86440-0.411804.341302.11060K562RECQL
LEPROTENSG00000213625.4881.680701438.87030-0.706607.128105.80110K562RPS19
LEPROTENSG00000213625.41487.804302292.44010-0.623707.137105.43360K562RPS3
LEPROTENSG00000213625.42582.792101867.806600.467508.583007.20590K562SF3A3
LEPROTENSG00000213625.41618.688202145.52110-0.406505.218004.02140K562SF3B4
LEPROTENSG00000213625.41366.60980978.330600.482104.526602.86980K562SLBP
LEPROTENSG00000213625.42569.764901913.608600.425204.837203.64150K562SRPK2
LEPROTENSG00000213625.41561.496702352.72440-0.591407.144106.01560K562SRSF1
LEPROTENSG00000213625.41838.827102213.13220-0.267302.258901.32650K562SRSF4
LEPROTENSG00000213625.43408.748802395.526300.508806.077304.00660K562SSRP1
LEPROTENSG00000213625.42484.585403145.41850-0.340204.584502.69300K562SUCLG1
LEPROTENSG00000213625.43911.021601924.997301.022603.492001.82670K562SUPT6H
LEPROTENSG00000213625.41139.097401652.96540-0.537207.478406.11490K562SYNCRIP
LEPROTENSG00000213625.41635.484702381.31200-0.542006.174805.08200K562TARDBP
LEPROTENSG00000213625.41897.723602296.99140-0.275502.521001.74440K562TIA1
LEPROTENSG00000213625.42223.269801483.704800.583407.549205.80880K562TRIM56
LEPROTENSG00000213625.42808.176601999.963800.489604.302002.87460K562U2AF1
LEPROTENSG00000213625.41599.471802007.07430-0.327504.793203.87420K562UPF1
LEPROTENSG00000213625.43002.957601717.389700.8061017.1593014.98510K562WDR3
LEPROTENSG00000213625.44328.426303299.345700.391604.162102.57300K562WRN
LEPROTENSG00000213625.44710.364503135.444900.587109.410007.69920K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LEPROT is not available on ENCORE database.





15 RBPs can affect the splicing of LEPROT :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELEPROTENSG00000213625.4chr1+6589554465895731658909856589106165897485659016900.079000.000160.02952includedK562MATR3
SELEPROTENSG00000213625.4chr1+6589346465893629658909856589106165895544658959860.092000.000140.00678includedK562AKAP8L
SELEPROTENSG00000213625.4chr1+6589346465893629658909856589106165895544658959860.250000.000000.00000includedK562PUS1
SELEPROTENSG00000213625.4chr1+658955446589573165890985658910616589748565901690-0.280000.000000.00000excludedK562PUS1
SELEPROTENSG00000213625.4chr1+658955446589573165890985658910616589748565901690-0.239000.000130.03256excludedK562MTPAP
SELEPROTENSG00000213625.4chr1+6589554465895731658909856589106165897485659016900.136000.000080.00290includedK562U2AF1
SELEPROTENSG00000213625.4chr1+658955446589573165890985658910616589748565901690-0.227000.000190.01845excludedK562HNRNPL
SELEPROTENSG00000213625.4chr1+658955446589573165890985658910616589748565901690-0.051000.003720.07084excludedHepG2SRSF1
SELEPROTENSG00000213625.4chr1+658955446589573165890985658910616589748565901690-0.104000.000190.03902excludedK562EIF4G2
SELEPROTENSG00000213625.4chr1+6589346465893629658909856589106165895544658959860.180000.000000.00004includedK562UTP18
SELEPROTENSG00000213625.4chr1+658955446589573165890985658910616589748565901690-0.151000.000410.01744excludedK562UTP18
SELEPROTENSG00000213625.4chr1+658955446589573165890985658910616589748565901690-0.370000.000000.00000excludedK562HNRNPU
SELEPROTENSG00000213625.4chr1+6589346465893629658909856589106165895544658959860.221000.000000.00000includedK562RBM15
SELEPROTENSG00000213625.4chr1+658955446589573165890985658910616589748565901690-0.126000.000880.02483excludedK562RBM15
SELEPROTENSG00000213625.4chr1+6589346465893629658909856589106165895544658959860.116000.000020.00130includedK562AGGF1
SELEPROTENSG00000213625.4chr1+6589554465895731658909856589106165897485659016900.083000.001050.04665includedK562HNRNPK
SELEPROTENSG00000213625.4chr1+658955446589573165890985658910616589748565901690-0.220000.000000.00012excludedHepG2HNRNPU
SELEPROTENSG00000213625.4chr1+6589346465893629658909856589106165895544658959860.069000.000580.02561includedHepG2HNRNPC
SELEPROTENSG00000213625.4chr1+6589554465895731658909856589106165897485659016900.077000.000680.02962includedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LEPROT is not avaliable on ENCORE database.