KLHL5

General Information

Gene Name       : KLHL5
Gene ID             : ENSG00000109790.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KLHL5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KLHL5ENSG00000109790.1612.7510.6811.71ENCSR000AEF
HepG2KLHL5ENSG00000109790.1624.3428.8326.59ENCSR985KAT
K562KLHL5ENSG00000109790.1615.2114.8915.05ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KLHL5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KLHL5 RNA is bound by 9 proteins.  







eCLIP assay for KLHL5 is not avaliable on ENCORE database.





9 proteins are bound to KLHL5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr43912370839123789+3'-UTR,intron-Distal3.419763.40672HepG2FUBP3
chr43907759439077666+3'-UTR,5'-UTR,CDS,intron-Distal4.099083.43253K562YBX3
chr43908274439082860+3'-UTR,CDS,intron-Proximal3.682277.83567HepG2BCLAF1
chr43906409439064152+5'-UTR,CDS,intron-Distal,intron-Proximal3.827803.45805K562KHSRP
chr43910491439104996+CDS3.706114.74886HepG2BCLAF1
chr43912261839122681+CDS,intron-Distal,intron-Proximal4.579374.64001HepG2U2AF2
chr43909832939098409+CDS4.419053.90287K562LIN28B
chr43908359239083669+CDS4.204304.93978HepG2BCLAF1
chr43910502739105124+CDS3.665306.60490HepG2BCLAF1
chr43908824039088282+CDS4.761623.02457HepG2BCLAF1
chr43908370739083773+CDS4.381367.53358HepG2BCLAF1
chr43911468339114820+CDS4.8488110.19430HepG2BCLAF1
chr43907386839073965+intron-Distal6.1601219.08022HepG2QKI
chr43906112039061166+intron-Distal5.246558.14577HepG2LIN28B
chr43905479539054850+intron-Distal3.373205.01093HepG2QKI
chr43906111939061167+intron-Distal6.1571412.47556K562LIN28B
chr43905448639054545+intron-Distal4.278593.16986HepG2QKI
chr43905485039054900+intron-Distal4.748254.51735HepG2QKI
chr43905456339054628+intron-Distal4.198488.08894HepG2QKI
chr43907385639073954+intron-Distal4.403625.51743K562QKI
chr43910438639104508+intron-Distal3.707254.36650HepG2SUGP2
chr43904673739046795+intron-Proximal3.495594.23616K562TIA1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KLHL5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KLHL5 is not available on ENCORE database.

  • 107 RBPs can affect the levels of KLHL5.  








The Knockdown/knockout RNA-Seq assay for KLHL5 is not available on ENCORE database.





107 RBPs can affect the gene expression of KLHL5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KLHL5ENSG00000109790.12909.65820612.835800.569705.257403.81850HepG2AATF
KLHL5ENSG00000109790.12579.03380947.99320-0.711207.520305.97950HepG2ADAR
KLHL5ENSG00000109790.122820.840801116.247801.3374024.0079022.61010HepG2AKAP1
KLHL5ENSG00000109790.121290.89520923.624500.482903.951903.01960HepG2ASCC1
KLHL5ENSG00000109790.12925.996901175.73500-0.344502.552901.97480HepG2BOP1
KLHL5ENSG00000109790.121849.802601044.355200.8247010.049608.71760HepG2CALR
KLHL5ENSG00000109790.12844.564301642.18060-0.9593010.657108.77740HepG2CCAR1
KLHL5ENSG00000109790.121126.75400877.499400.360602.409401.68250HepG2CIRBP
KLHL5ENSG00000109790.121840.004201079.382500.7694011.081509.80560HepG2CPSF6
KLHL5ENSG00000109790.121863.472901199.878400.6350012.7239011.54170HepG2CELF1
KLHL5ENSG00000109790.121093.017501290.35250-0.239402.882702.12740HepG2DAZAP1
KLHL5ENSG00000109790.12910.74610661.771200.460603.478002.44710HepG2DDX24
KLHL5ENSG00000109790.121351.534901069.330600.337802.178901.61650HepG2DDX3X
KLHL5ENSG00000109790.121837.658301225.720200.584103.015101.99570HepG2DDX59
KLHL5ENSG00000109790.122734.42980918.460201.5739032.5802030.80020HepG2DDX6
KLHL5ENSG00000109790.12691.97570920.68480-0.412003.276902.21450HepG2DHX30
KLHL5ENSG00000109790.121125.61080954.559900.237701.934101.33460HepG2DNAJC21
KLHL5ENSG00000109790.12928.72230622.795800.576402.305601.30180HepG2AGO1
KLHL5ENSG00000109790.121025.00330685.237900.580905.252504.03510HepG2EIF3D
KLHL5ENSG00000109790.12838.18940638.802900.391802.499501.47160HepG2EIF3G
KLHL5ENSG00000109790.122030.89600975.934701.0572015.3444013.85610HepG2EIF4A3
KLHL5ENSG00000109790.121509.47690950.102300.667803.870903.06250HepG2EIF4B
KLHL5ENSG00000109790.123005.877302194.193300.454009.800508.78060HepG2ETF1
KLHL5ENSG00000109790.121138.19310644.730300.8199010.840208.82790HepG2FASTKD2
KLHL5ENSG00000109790.122113.394701187.667700.8313010.541109.17530HepG2FIP1L1
KLHL5ENSG00000109790.121153.81030913.364300.337002.033201.45980HepG2G3BP1
KLHL5ENSG00000109790.121492.63170969.536500.622406.559005.18070HepG2G3BP2
KLHL5ENSG00000109790.121135.68840773.037300.554903.202401.50210HepG2GTF2F1
KLHL5ENSG00000109790.121171.42630932.834500.328503.806102.67490HepG2HDGF
KLHL5ENSG00000109790.121304.00180785.982100.730304.431102.64030HepG2HLTF
KLHL5ENSG00000109790.12695.72920963.70540-0.470104.141803.37440HepG2HNRNPA1
KLHL5ENSG00000109790.12282.214801167.65510-2.0487046.4919044.41660HepG2HNRNPLL
KLHL5ENSG00000109790.12541.82740819.70340-0.597303.961302.84260HepG2HNRNPM
KLHL5ENSG00000109790.12900.961101064.87330-0.241102.110601.57290HepG2HNRNPU
KLHL5ENSG00000109790.121518.78340928.446600.709908.138807.04430HepG2IGF2BP2
KLHL5ENSG00000109790.123139.46240871.179101.849407.753506.17070HepG2IGF2BP3
KLHL5ENSG00000109790.121650.577701087.729800.6016015.7926014.20290HepG2ILF2
KLHL5ENSG00000109790.121337.950301824.49800-0.447503.046601.78310HepG2KHDRBS1
KLHL5ENSG00000109790.121084.22700860.473800.333402.579701.48280HepG2LARP7
KLHL5ENSG00000109790.121481.30150990.390000.580704.950204.12730HepG2MATR3
KLHL5ENSG00000109790.121193.89750717.161700.735205.067303.66950HepG2METAP2
KLHL5ENSG00000109790.12550.12900961.63930-0.805705.920004.77820HepG2MSI2
KLHL5ENSG00000109790.121054.010101279.50080-0.279702.653401.90680HepG2NOL12
KLHL5ENSG00000109790.121366.959501035.362000.400703.307402.48910HepG2NSUN2
KLHL5ENSG00000109790.122453.55110902.906301.4421031.1905028.83960HepG2PABPC4
KLHL5ENSG00000109790.121234.71840904.830100.448406.230005.37500HepG2PCBP1
KLHL5ENSG00000109790.12716.951201015.90390-0.502806.844205.68980HepG2PRPF4
KLHL5ENSG00000109790.12386.22620640.59230-0.730005.735204.61800HepG2PRPF8
KLHL5ENSG00000109790.121460.90740920.666400.6660013.1352012.11970HepG2PTBP1
KLHL5ENSG00000109790.12811.187901221.34310-0.590407.227306.32180HepG2PUF60
KLHL5ENSG00000109790.121363.98500997.172800.451805.242204.42280HepG2QKI
KLHL5ENSG00000109790.121348.91040749.667300.847405.685504.69770HepG2RAVER1
KLHL5ENSG00000109790.122008.376701245.482500.6892012.7011011.07200HepG2RBM15
KLHL5ENSG00000109790.122173.479301833.951800.245002.628302.12050HepG2RBM22
KLHL5ENSG00000109790.121648.36950904.972600.8650015.6803014.14380HepG2RBM25
KLHL5ENSG00000109790.121858.708501024.640000.8591022.6658021.41000HepG2NELFE
KLHL5ENSG00000109790.121340.00500954.264600.489707.278406.34960HepG2RECQL
KLHL5ENSG00000109790.121375.746801922.74380-0.483003.200202.34170HepG2RPS3A
KLHL5ENSG00000109790.121316.72140976.805200.430703.684502.43610HepG2RPS5
KLHL5ENSG00000109790.121109.30230633.683400.807708.157806.89620HepG2RRP9
KLHL5ENSG00000109790.121498.11460815.362700.877507.286904.90820HepG2RTF1
KLHL5ENSG00000109790.12532.05630948.30630-0.8338017.0711015.66720HepG2SAFB2
KLHL5ENSG00000109790.121255.061701826.72360-0.541503.127201.47360HepG2SBDS
KLHL5ENSG00000109790.12742.781001155.73810-0.637806.974905.89670HepG2SF3B1
KLHL5ENSG00000109790.121565.61890958.590100.7076015.1583013.94130HepG2SF3B4
KLHL5ENSG00000109790.12967.749701170.95170-0.275003.309302.55270HepG2SLBP
KLHL5ENSG00000109790.121295.27470763.860400.761806.471204.95850HepG2SMNDC1
KLHL5ENSG00000109790.123921.724702071.402700.9208044.3460042.97190HepG2SRFBP1
KLHL5ENSG00000109790.121685.319201000.537000.7521018.2349017.24540HepG2SRSF1
KLHL5ENSG00000109790.121408.119601205.824900.223601.882401.35250HepG2SRSF5
KLHL5ENSG00000109790.121344.38230813.970000.7238016.3866015.24560HepG2SRSF9
KLHL5ENSG00000109790.121189.06930700.555900.763205.680903.96580HepG2SUB1
KLHL5ENSG00000109790.12487.75790802.32930-0.718005.015403.76790HepG2SUPT6H
KLHL5ENSG00000109790.121815.62580826.606401.1351017.1163015.68440HepG2SUPV3L1
KLHL5ENSG00000109790.123189.66700899.256601.8265099.5474096.81450HepG2TAF15
KLHL5ENSG00000109790.121491.826501138.147400.390303.283802.50110HepG2TARDBP
KLHL5ENSG00000109790.12794.064101607.18370-1.017206.002104.49360HepG2TBRG4
KLHL5ENSG00000109790.12795.07230554.054400.521003.530102.42040HepG2TFIP11
KLHL5ENSG00000109790.121543.19390826.363400.9010017.7614015.70650HepG2TIA1
KLHL5ENSG00000109790.12809.729601034.65680-0.353603.225102.69210HepG2TIAL1
KLHL5ENSG00000109790.12445.94160752.58810-0.755005.111303.16450HepG2TRA2A
KLHL5ENSG00000109790.12807.976801043.97740-0.369704.268003.59730HepG2TRIM56
KLHL5ENSG00000109790.122111.348301262.812000.741408.280006.80030HepG2UBE2L3
KLHL5ENSG00000109790.12335.30150488.31200-0.542303.366902.53310HepG2UCHL5
KLHL5ENSG00000109790.12397.32750756.95770-0.929906.698205.09240HepG2UPF2
KLHL5ENSG00000109790.12698.51570893.89010-0.355803.352002.21240HepG2UTP18
KLHL5ENSG00000109790.12505.28510839.63590-0.7327011.6774010.58150HepG2UTP3
KLHL5ENSG00000109790.121184.111101722.18770-0.540403.696702.42490HepG2XPO5
KLHL5ENSG00000109790.121473.34900737.019200.999209.743707.49610HepG2XRCC5
KLHL5ENSG00000109790.121571.00970824.342300.930309.016207.22150HepG2XRCC6
KLHL5ENSG00000109790.12510.96640813.70290-0.671305.500204.48920HepG2XRN2
KLHL5ENSG00000109790.121410.69350956.475500.5605012.4159011.46520HepG2ZNF622
KLHL5ENSG00000109790.12872.883001062.41730-0.283502.618802.06320K562AGGF1
KLHL5ENSG00000109790.12776.994001105.48520-0.508704.915804.03510K562AKAP8L
KLHL5ENSG00000109790.12454.938401066.78030-1.2295020.1521018.73740K562AQR
KLHL5ENSG00000109790.12230.50090313.64150-0.444302.271201.33300K562CCAR1
KLHL5ENSG00000109790.12792.63420633.499700.323202.241301.31170K562DDX3X
KLHL5ENSG00000109790.12405.06520588.66980-0.539302.890501.58120K562EEF2
KLHL5ENSG00000109790.12445.51360695.78110-0.643208.527406.37800K562EIF2S1
KLHL5ENSG00000109790.12861.47010664.694400.374003.629602.82490K562EIF2S2
KLHL5ENSG00000109790.12391.54730661.82710-0.757308.066906.66690K562EIF4A3
KLHL5ENSG00000109790.12415.29520595.98850-0.521105.034903.40950K562EIF4B
KLHL5ENSG00000109790.12593.18560772.38850-0.380802.988801.87200K562HNRNPA1
KLHL5ENSG00000109790.12327.91470653.50190-0.9949012.1033010.92880K562HNRNPC
KLHL5ENSG00000109790.121586.20370958.922000.726009.388807.94320K562HSPD1
KLHL5ENSG00000109790.12642.92250928.75620-0.530705.304904.13120K562MAGOH
KLHL5ENSG00000109790.12518.17670952.59070-0.878404.401103.07650K562PABPN1
KLHL5ENSG00000109790.12797.74450568.053400.489803.248802.34640K562PCBP3
KLHL5ENSG00000109790.12604.20570435.722900.471503.662802.73470K562POLR2G
KLHL5ENSG00000109790.12396.27510553.47640-0.482002.907802.14040K562PRPF8
KLHL5ENSG00000109790.12434.11810585.90740-0.432602.595701.72620K562PSIP1
KLHL5ENSG00000109790.12725.89560902.34140-0.313902.373301.75030K562PTBP1
KLHL5ENSG00000109790.121098.134101396.35640-0.346602.799501.97950K562PUF60
KLHL5ENSG00000109790.12710.582501096.39630-0.625706.542305.74810K562PUS1
KLHL5ENSG00000109790.12722.585601068.22470-0.564007.232406.30490K562RBM15
KLHL5ENSG00000109790.12545.94160865.26260-0.664407.105605.68280K562RBM22
KLHL5ENSG00000109790.12521.36130871.41670-0.741102.675101.50010K562SF1
KLHL5ENSG00000109790.12519.32100798.11040-0.620002.602801.77650K562SF3B4
KLHL5ENSG00000109790.12697.51860884.59030-0.342802.563001.87890K562SRSF1
KLHL5ENSG00000109790.12652.19500835.41620-0.357202.421901.44980K562SRSF5
KLHL5ENSG00000109790.12394.94180535.87800-0.440302.321101.39470K562SUPV3L1
KLHL5ENSG00000109790.12697.13700895.27410-0.360902.397701.73650K562TARDBP
KLHL5ENSG00000109790.12591.77890847.41260-0.518004.425702.98730K562TRA2A
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KLHL5 is not available on ENCORE database.





11 RBPs can affect the splicing of KLHL5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.248000.001750.09033includedHepG2RBM22
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.265000.000020.00078includedHepG2U2AF1
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.212000.000250.03777includedHepG2HNRNPM
SEKLHL5ENSG00000109790.12chr4+390641783906465539046658390467163907758439077767-0.410000.000020.00092excludedHepG2HNRNPK
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.152000.000010.00017includedHepG2U2AF2
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.243000.000000.00000includedHepG2SFPQ
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.208000.000040.01419includedK562GPKOW
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.100000.000150.01542includedHepG2FTO
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.162000.000690.09486includedK562FXR2
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.142000.000010.02308includedHepG2RBM5
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.250000.001700.03078includedK562U2AF2
SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.325000.000000.00027includedK562SF3B1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KLHL5 is not avaliable on ENCORE database.