UBE4A

General Information

Gene Name       : UBE4A
Gene ID             : ENSG00000110344.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: UBE4A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UBE4AENSG00000110344.922.4120.0721.24ENCSR000AEF
HepG2UBE4AENSG00000110344.910.7817.7214.25ENCSR985KAT
K562UBE4AENSG00000110344.921.0622.0721.56ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for UBE4A is not avaliable on ENCORE database.



Proteins bound to RNA
  • UBE4A RNA is bound by 18 proteins.  







eCLIP assay for UBE4A is not avaliable on ENCORE database.





18 proteins are bound to UBE4A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11118267390118267456+3'-UTR3.497384.12870K562PTBP1
chr11118268155118268193+3'-UTR4.579359.25286K562PUM2
chr11118267412118267467+3'-UTR4.233884.40847HepG2PTBP1
chr11118268103118268145+3'-UTR4.266544.96821K562PUM2
chr11118267634118267689+3'-UTR4.111653.54770K562IGF2BP1
chr11118268522118268566+3'-UTR3.354374.41952K562IGF2BP1
chr11118267291118267366+3'-UTR4.178154.00100K562TIA1
chr11118269640118269738+3'-UTR4.257354.78334K562IGF2BP2
chr11118267878118267956+3'-UTR4.052638.45745K562IGF2BP1
chr11118269257118269292+3'-UTR5.851515.13070K562PUM2
chr11118267472118267519+3'-UTR3.386664.70908HepG2QKI
chr11118267581118267655+3'-UTR3.935467.65820K562PUM2
chr11118268176118268256+3'-UTR3.659495.92005K562IGF2BP1
chr11118267470118267541+3'-UTR3.559605.00400K562QKI
chr11118235750118235823+5'-UTR,CDS,intron-Proximal3.234224.47117K562DDX3X
chr11118250147118250192+5'-UTR,CDS,intron-Proximal4.033163.18234K562BUD13
chr11118230333118230390+5'-UTR,intron-Proximal4.397754.66990HepG2DDX3X
chr11118250161118250189+5'-UTR,CDS3.644656.39464HepG2BCLAF1
chr11118235789118235904+5'-UTR,CDS3.239208.80715HepG2BCLAF1
chr11118247302118247352+CDS3.750266.60490HepG2BCLAF1
chr11118260545118260592+CDS3.366864.93097K562YBX3
chr11118243805118243944+CDS3.4847113.50876HepG2BCLAF1
chr11118244389118244473+CDS,intron-Proximal4.153076.39176K562AQR
chr11118252222118252314+CDS,intron-Proximal4.265436.71940K562PRPF8
chr11118239411118239487+CDS3.238966.13091K562YBX3
chr11118244207118244226+CDS,intron-Proximal4.084629.37631HepG2BCLAF1
chr11118247292118247361+CDS3.078993.80065HepG2PPIG
chr11118253484118253555+CDS,intron-Proximal3.378393.18246K562PRPF8
chr11118263493118263565+CDS4.285036.22576HepG2BCLAF1
chr11118252230118252290+CDS,intron-Proximal4.976195.35117HepG2PRPF8
chr11118257167118257255+CDS3.786526.46787HepG2GRWD1
chr11118252168118252362+CDS,intron-Distal,intron-Proximal3.088683.37686K562BUD13
chr11118242355118242381+CDS3.665304.46864HepG2BCLAF1
chr11118260444118260545+CDS4.1840418.00982K562YBX3
chr11118240203118240229+CDS4.554104.78529HepG2BCLAF1
chr11118243969118244005+CDS,intron-Proximal3.9447811.60362HepG2BCLAF1
chr11118257152118257201+CDS,intron-Proximal3.160183.09884K562LIN28B
chr11118247360118247409+CDS4.511108.41475HepG2BCLAF1
chr11118235837118235885+CDS3.054083.41665HepG2GRWD1
chr11118253303118253390+CDS,intron-Proximal3.845605.97760HepG2G3BP1
chr11118255404118255447+CDS3.780963.11282HepG2G3BP1
chr11118253373118253420+CDS4.438424.94878HepG2GRWD1
chr11118252689118252752+intron-Distal3.5462910.79618HepG2U2AF2
chr11118231738118231797+intron-Distal3.751243.15106HepG2HNRNPC
chr11118249726118249814+intron-Distal,intron-Proximal4.653604.85866HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for UBE4A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for UBE4A is not available on ENCORE database.

  • 65 RBPs can affect the levels of UBE4A.  








The Knockdown/knockout RNA-Seq assay for UBE4A is not available on ENCORE database.





65 RBPs can affect the gene expression of UBE4A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
UBE4AENSG00000110344.51285.768401797.51420-0.483404.261203.29530HepG2ASCC1
UBE4AENSG00000110344.51969.071102291.29940-0.218702.594801.92690HepG2AUH
UBE4AENSG00000110344.52326.717701836.564900.341203.120802.48950HepG2BOP1
UBE4AENSG00000110344.51929.406701548.906200.316803.033002.22770HepG2CALR
UBE4AENSG00000110344.51407.026301950.74870-0.471408.300107.29940HepG2CELF1
UBE4AENSG00000110344.51856.441202097.81560-0.176302.367901.67420HepG2DAZAP1
UBE4AENSG00000110344.52210.801301413.164600.645509.252508.08800HepG2DDX21
UBE4AENSG00000110344.51762.765001382.325400.350603.355302.34390HepG2DDX24
UBE4AENSG00000110344.51833.374001338.516000.453803.380901.96950HepG2DDX27
UBE4AENSG00000110344.51346.899401787.48020-0.408302.785302.16560HepG2DDX6
UBE4AENSG00000110344.51988.937001549.758600.359903.264002.53840HepG2DKC1
UBE4AENSG00000110344.51113.482101306.37230-0.230501.972101.36740HepG2DNAJC21
UBE4AENSG00000110344.51357.398001086.411700.321202.173101.36250HepG2EIF3D
UBE4AENSG00000110344.52432.059701899.304100.356602.418601.81960HepG2EIF4A3
UBE4AENSG00000110344.52732.208002069.381100.400806.275805.10700HepG2EIF4G1
UBE4AENSG00000110344.51242.147801018.881500.285802.052401.36690HepG2FUBP3
UBE4AENSG00000110344.51072.917701466.98270-0.451304.356703.50170HepG2HNRNPC
UBE4AENSG00000110344.51425.108101911.03490-0.423309.246008.08230HepG2HNRNPL
UBE4AENSG00000110344.52453.225801824.117500.427404.038703.29300HepG2HNRNPLL
UBE4AENSG00000110344.51267.214001488.57580-0.232302.355301.67140HepG2ILF2
UBE4AENSG00000110344.51390.666101927.46070-0.470903.648102.93290HepG2MATR3
UBE4AENSG00000110344.51896.444801485.442200.352303.556802.64160HepG2MSI2
UBE4AENSG00000110344.51610.594902080.17450-0.369104.900303.88930HepG2NOL12
UBE4AENSG00000110344.51684.610301103.694100.610006.709805.51330HepG2PRPF8
UBE4AENSG00000110344.52238.534801672.278000.420601.924501.32620HepG2RAVER1
UBE4AENSG00000110344.51419.214601060.988200.419603.618302.53720HepG2SERBP1
UBE4AENSG00000110344.51110.381101513.48690-0.446808.859207.81270HepG2SMN1
UBE4AENSG00000110344.51915.867702483.45090-0.374306.874306.18280HepG2SRFBP1
UBE4AENSG00000110344.52879.003501959.494700.5550014.0852013.19560HepG2SRSF1
UBE4AENSG00000110344.52920.049902156.234300.437409.752208.90320HepG2SSB
UBE4AENSG00000110344.52071.818901761.121700.234302.187401.67870HepG2TAF15
UBE4AENSG00000110344.51083.296501416.15640-0.386604.111003.52730HepG2TIAL1
UBE4AENSG00000110344.51241.565801428.67590-0.202501.975301.48340HepG2TRIM56
UBE4AENSG00000110344.52628.965002053.072300.356602.368901.59880HepG2UBE2L3
UBE4AENSG00000110344.51588.250801928.28530-0.279903.845103.04210HepG2UPF1
UBE4AENSG00000110344.52076.733201561.111000.411608.454407.38740HepG2ZC3H8
UBE4AENSG00000110344.51763.126102789.64800-0.6619018.7897017.43390K562AGGF1
UBE4AENSG00000110344.52463.101603065.27200-0.315502.951301.92600K562AKAP8
UBE4AENSG00000110344.51909.292802902.72330-0.604408.939007.69070K562AKAP8L
UBE4AENSG00000110344.54461.413903139.976700.506606.154405.33880K562AQR
UBE4AENSG00000110344.52494.261303045.59540-0.288103.629702.57190K562ATP5C1
UBE4AENSG00000110344.52734.252001967.993300.474304.922103.74460K562BOP1
UBE4AENSG00000110344.52576.187903333.88580-0.372004.950403.33150K562CCDC124
UBE4AENSG00000110344.51323.970001652.03500-0.319403.545202.21230K562EIF4B
UBE4AENSG00000110344.51220.807501601.31050-0.391404.910503.09620K562EWSR1
UBE4AENSG00000110344.52193.977402641.16340-0.267602.101201.35860K562FIP1L1
UBE4AENSG00000110344.52550.572801993.626900.355302.081501.47970K562G3BP2
UBE4AENSG00000110344.52714.930203422.99600-0.334303.449002.60670K562GRSF1
UBE4AENSG00000110344.52374.939103080.62650-0.375304.304603.24510K562KIF1C
UBE4AENSG00000110344.52012.875902515.07520-0.321302.949202.08140K562MAGOH
UBE4AENSG00000110344.52250.013502948.82710-0.390203.737202.42140K562MAK16
UBE4AENSG00000110344.51848.572302509.97180-0.441305.604904.23040K562MATR3
UBE4AENSG00000110344.52785.079903451.06420-0.309303.271402.26840K562MBNL1
UBE4AENSG00000110344.51776.722502418.93630-0.445203.050102.11660K562NAA15
UBE4AENSG00000110344.51234.536101960.42040-0.667203.165702.08690K562PABPN1
UBE4AENSG00000110344.52105.522102998.19230-0.509906.074404.77930K562PPIG
UBE4AENSG00000110344.52388.622301837.178900.378603.511302.66520K562PRPF8
UBE4AENSG00000110344.51086.922601418.15360-0.383802.957802.01760K562PSIP1
UBE4AENSG00000110344.52143.826802878.93290-0.425304.430903.76640K562PUS1
UBE4AENSG00000110344.52034.597902804.89760-0.463207.824006.85770K562RBM15
UBE4AENSG00000110344.51637.636301972.39980-0.268303.253501.53620K562RPS10
UBE4AENSG00000110344.51382.461602186.10170-0.661102.865101.53030K562SFPQ
UBE4AENSG00000110344.51742.981202262.36910-0.376303.485102.28300K562SRSF5
UBE4AENSG00000110344.52448.721002092.158500.226902.025901.32340K562SYNCRIP
UBE4AENSG00000110344.51241.874002424.39850-0.9651017.4748015.38100K562TARDBP
UBE4AENSG00000110344.51752.396802338.60660-0.416305.024403.86960K562TIA1
UBE4AENSG00000110344.51828.555902294.87240-0.327702.806001.70350K562TRA2A
UBE4AENSG00000110344.52018.943002918.70750-0.531702.527201.31320K562UTP18
UBE4AENSG00000110344.52875.199603537.28940-0.299002.750001.88990K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for UBE4A is not available on ENCORE database.





12 RBPs can affect the splicing of UBE4A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUBE4AENSG00000110344.5chr11+1182527291182529131182521051182522381182533031182534910.055000.000170.03913includedK562FTO
SEUBE4AENSG00000110344.5chr11+118255546118255660118255349118255450118257152118257327-0.105000.002150.03870excludedK562SF3B4
SEUBE4AENSG00000110344.5chr11+1182527291182529131182521051182522381182533031182534910.062000.000010.00322includedK562FMR1
SEUBE4AENSG00000110344.5chr11+1182527291182529131182521051182522381182533031182534910.070000.006050.05442includedK562AQR
SEUBE4AENSG00000110344.5chr11+118255546118255660118255349118255450118257152118257327-0.161000.000000.00000excludedK562AQR
SEUBE4AENSG00000110344.5chr11+118260439118260620118257152118257327118261371118261519-0.060000.011570.09116excludedK562AQR
SEUBE4AENSG00000110344.5chr11+118245610118245944118244208118244400118247288118247409-0.099000.005190.04795excludedK562AQR
SEUBE4AENSG00000110344.5chr11+1182527291182529131182521051182522381182533031182534910.061000.000020.00850includedK562GPKOW
SEUBE4AENSG00000110344.5chr11+1182348621182349931182302991182303891182357541182359160.080000.000150.00964includedHepG2MATR3
SEUBE4AENSG00000110344.5chr11+118245610118245944118244208118244400118247288118247409-0.158000.001050.02362excludedK562U2AF1
SEUBE4AENSG00000110344.5chr11+1182527291182529001182521051182522381182533031182534910.084000.001890.04217includedHepG2SRSF1
SEUBE4AENSG00000110344.5chr11+1182527291182529131182521051182522381182533031182534910.190000.000030.01875includedHepG2BCCIP
SEUBE4AENSG00000110344.5chr11+1182527291182529131182521051182522381182533031182534910.084000.000840.09128includedK562RBM22
SEUBE4AENSG00000110344.5chr11+1182527291182529131182521051182522381182533031182534910.059000.000020.00540includedK562CPSF6
SEUBE4AENSG00000110344.5chr11+118255546118255660118255349118255450118257152118257327-0.210000.002930.09047excludedK562SF3B1
A3SSUBE4AENSG00000110344.5chr11+1182501361182503531182501601182503531182472881182474090.081000.000050.00049longerK562AQR
A3SSUBE4AENSG00000110344.5chr11+1182613461182615191182613711182615191182604391182606200.173000.000000.00000longerK562AQR
A3SSUBE4AENSG00000110344.5chr11+1182520861182522381182521051182522381182501601182504650.074000.000020.00021longerK562AQR
A3SSUBE4AENSG00000110344.5chr11+1182634371182636101182634521182636101182613711182615190.065000.000100.00086longerK562AQR
MXEUBE4AENSG00000110344.5chr11+1182442081182444001182456101182459441182432211182433811182472881182474090.104000.003340.025601includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for UBE4A is not avaliable on ENCORE database.