CUL5

General Information

Gene Name       : CUL5
Gene ID             : ENSG00000166266.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CUL5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CUL5ENSG00000166266.1318.2312.6815.46ENCSR000AEF
HepG2CUL5ENSG00000166266.135.8211.918.87ENCSR985KAT
K562CUL5ENSG00000166266.1314.8215.1114.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CUL5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CUL5 RNA is bound by 23 proteins.  







eCLIP assay for CUL5 is not avaliable on ENCORE database.





23 proteins are bound to CUL5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11107978272107978361+3'-UTR3.042066.92889K562KHSRP
chr11107976650107976694+3'-UTR,intron-Distal3.179685.58482K562YBX3
chr11107925373107925513+3'-UTR,CDS,intron-Proximal3.339137.70439HepG2BCLAF1
chr11107977604107977651+3'-UTR4.703085.38606K562FAM120A
chr11107978344107978405+3'-UTR3.046033.91951K562PUM2
chr11107925602107925680+3'-UTR,CDS4.9663211.99174HepG2BCLAF1
chr11107879833107879884+5'-UTR4.159763.48187K562RBM15
chr11107879633107879780+5'-UTR3.924635.06399K562DDX3X
chr11107880073107880187+5'-UTR,CDS,intron-Proximal5.281538.04585HepG2PRPF8
chr11107969178107969211+CDS4.377103.71570HepG2BCLAF1
chr11107943085107943187+CDS3.7203911.19453HepG2BCLAF1
chr11107968339107968393+CDS,intron-Proximal5.103135.00483K562GPKOW
chr11107940772107940838+CDS,intron-Proximal3.921476.67591K562SF3B4
chr11107940819107940866+CDS,intron-Proximal4.611076.22576HepG2BCLAF1
chr11107968451107968516+CDS,intron-Proximal4.662805.01842HepG2PRPF8
chr11107966354107966431+CDS,intron-Proximal4.301817.97334HepG2BCLAF1
chr11107966353107966417+CDS3.278323.12941K562UCHL5
chr11107904626107904675+CDS,intron-Proximal3.903714.93376K562PRPF8
chr11107940818107940907+CDS,intron-Proximal3.946213.31827HepG2GRWD1
chr11107965611107965671+CDS3.567343.68471HepG2BCLAF1
chr11107943097107943190+CDS,intron-Proximal4.559404.90367K562ZNF622
chr11107904606107904674+CDS,intron-Proximal5.690124.35676HepG2PRPF8
chr11107959253107959342+CDS,intron-Proximal3.469147.74581HepG2BCLAF1
chr11107944184107944227+CDS,intron-Proximal4.023405.94293HepG2BCLAF1
chr11107940866107940915+CDS3.819365.97823HepG2BCLAF1
chr11107968344107968416+CDS,intron-Proximal3.627567.96049HepG2U2AF2
chr11107948904107948965+CDS5.372828.86847HepG2BCLAF1
chr11107969143107969255+CDS3.452705.65306K562ZNF622
chr11107968983107969105+intron-Distal,intron-Proximal3.361234.76825K562KHSRP
chr11107880549107880689+intron-Distal4.765156.17200HepG2PCBP2
chr11107955730107955745+intron-Distal6.53581400.00000K562TROVE2
chr11107884170107884271+intron-Distal4.446514.75674K562MATR3
chr11107883014107883118+intron-Distal3.039623.43871K562MATR3
chr11107955686107955744+intron-Distal5.032477.14377HepG2TROVE2
chr11107968247107968336+intron-Distal,intron-Proximal3.106595.82594K562KHSRP
chr11107932844107932918+intron-Distal4.302774.17759HepG2QKI
chr11107955690107955743+intron-Distal3.754614.27496K562PCBP1
chr11107883029107883122+intron-Distal4.208003.62238HepG2MATR3
chr11107922225107922340+intron-Distal3.175525.34873K562KHSRP
chr11107884017107884107+intron-Distal3.561823.56409K562MATR3
chr11107950547107950675+intron-Distal3.125203.51696K562KHSRP
chr11107925805107925881+intron-Distal3.544284.72639K562KHSRP
chr11107952927107953014+intron-Distal5.118637.79030HepG2PCBP2
chr11107896135107896258+intron-Distal3.526754.33009HepG2SUGP2
chr11107896858107896922+intron-Distal4.439264.24113K562MATR3
chr11107898619107898726+intron-Distal4.865826.01663K562MATR3
chr11107896393107896483+intron-Distal4.327754.86548HepG2SUGP2
chr11107897091107897165+intron-Distal3.883903.14791K562HNRNPL
chr11107955689107955743+intron-Distal3.6616213.15124K562YBX3
chr11107968168107968247+intron-Distal3.240064.35941K562KHSRP
chr11107955687107955726+intron-Distal6.88668400.00000K562TROVE2
chr11107884197107884250+intron-Distal3.016543.10883HepG2SUGP2
chr11107886958107887040+intron-Distal4.365516.85458K562PTBP1
chr11107896872107896957+intron-Distal4.352004.53347HepG2SUGP2
chr11107955696107955744+intron-Distal3.1568410.08373K562TIA1
chr11107966425107966528+intron-Distal,intron-Proximal4.326885.41654K562KHSRP
chr11107918475107918558+intron-Distal3.770073.26999K562KHSRP
chr11107940104107940148+intron-Distal4.289863.42734K562PTBP1
chr11107896670107896732+intron-Distal4.146783.47525K562MATR3
chr11107955726107955730+intron-Distal6.85168400.00000K562TROVE2
chr11107960021107960148+intron-Distal,intron-Proximal4.330003.55640HepG2QKI
chr11107932923107933037+intron-Distal3.812614.52298HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CUL5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CUL5 is not available on ENCORE database.

  • 67 RBPs can affect the levels of CUL5.  








The Knockdown/knockout RNA-Seq assay for CUL5 is not available on ENCORE database.





67 RBPs can affect the gene expression of CUL5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CUL5ENSG00000166266.9950.230101272.62030-0.421504.234503.41730HepG2AUH
CUL5ENSG00000166266.9438.58460762.56180-0.798004.712003.48920HepG2BCCIP
CUL5ENSG00000166266.9744.87390933.19880-0.325202.074301.55070HepG2BOP1
CUL5ENSG00000166266.9585.55290856.75240-0.549104.479903.62330HepG2CPSF6
CUL5ENSG00000166266.9823.431601003.09910-0.284702.715502.07790HepG2CELF1
CUL5ENSG00000166266.9497.07800749.70640-0.592902.846202.06270HepG2DDX55
CUL5ENSG00000166266.9682.58820972.89700-0.511302.268401.38620HepG2DDX59
CUL5ENSG00000166266.9639.21550942.87290-0.560804.000503.26890HepG2DDX6
CUL5ENSG00000166266.9576.13570757.76660-0.395303.349402.61410HepG2DKC1
CUL5ENSG00000166266.9506.62950707.34790-0.481506.017405.10980HepG2DNAJC2
CUL5ENSG00000166266.9657.85750906.42210-0.462403.282302.64030HepG2EIF2S1
CUL5ENSG00000166266.9755.19670543.455900.474603.432502.43140HepG2EIF3D
CUL5ENSG00000166266.91745.173501461.034700.256301.923401.40290HepG2ETF1
CUL5ENSG00000166266.9635.60530457.531600.474203.515902.63410HepG2FUBP3
CUL5ENSG00000166266.9783.923701010.66120-0.366502.314401.67930HepG2FXR1
CUL5ENSG00000166266.9539.91410720.52520-0.416303.005602.33480HepG2HNRNPA1
CUL5ENSG00000166266.9648.28590859.56770-0.407004.159503.29900HepG2HNRNPF
CUL5ENSG00000166266.9835.28520982.73370-0.234502.484801.84300HepG2HNRNPL
CUL5ENSG00000166266.9592.21480796.14070-0.426904.676503.90580HepG2HNRNPU
CUL5ENSG00000166266.9686.80560846.43330-0.301501.992401.37050HepG2IGF2BP1
CUL5ENSG00000166266.9634.05280813.23350-0.359104.099003.22330HepG2ILF2
CUL5ENSG00000166266.9522.83570818.72100-0.647003.098701.77330HepG2KRR1
CUL5ENSG00000166266.9823.261701069.69470-0.377803.253902.42930HepG2NOL12
CUL5ENSG00000166266.9597.08110821.81470-0.460902.979702.20390HepG2NSUN2
CUL5ENSG00000166266.9822.26020578.610000.506904.208903.23570HepG2PRPF8
CUL5ENSG00000166266.9838.682401021.06420-0.283902.099601.57020HepG2PUF60
CUL5ENSG00000166266.91291.300401010.085700.354203.635502.93390HepG2QKI
CUL5ENSG00000166266.91363.02070827.741100.719504.288503.42060HepG2RAVER1
CUL5ENSG00000166266.91469.28730916.760500.6804010.166408.93440HepG2RBM25
CUL5ENSG00000166266.9785.13220572.391800.455803.270202.42440HepG2RRP9
CUL5ENSG00000166266.9590.94940709.00600-0.262802.028501.46370HepG2SAFB2
CUL5ENSG00000166266.91174.16370895.954200.390001.891101.33080HepG2SF3A3
CUL5ENSG00000166266.91179.58830971.025200.280602.799902.20520HepG2SF3B4
CUL5ENSG00000166266.9630.18610843.19450-0.420102.225901.37590HepG2SMNDC1
CUL5ENSG00000166266.92119.939501013.579001.0645039.6621038.32790HepG2SRSF1
CUL5ENSG00000166266.9660.89450844.48120-0.353603.242002.49510HepG2SRSF7
CUL5ENSG00000166266.9951.39020746.400100.350002.379201.74560HepG2SUPV3L1
CUL5ENSG00000166266.91114.21910911.152400.290202.632702.08460HepG2TAF15
CUL5ENSG00000166266.9487.25300773.64710-0.667008.057107.28460HepG2TIAL1
CUL5ENSG00000166266.9504.99640780.51180-0.628109.147308.21380HepG2TRIM56
CUL5ENSG00000166266.91132.75970813.705200.477202.643001.41700HepG2XRCC5
CUL5ENSG00000166266.9516.58740734.74670-0.508202.316901.64840HepG2XRN2
CUL5ENSG00000166266.91083.93130873.880300.310703.772903.16040HepG2ZNF622
CUL5ENSG00000166266.91412.635201776.86870-0.330904.469003.77770K562AGGF1
CUL5ENSG00000166266.91449.447701848.89890-0.351203.119102.42440K562AKAP8L
CUL5ENSG00000166266.92174.552602781.21450-0.355003.682601.39940K562AUH
CUL5ENSG00000166266.91195.417601443.67990-0.272202.167101.46430K562CPSF6
CUL5ENSG00000166266.94465.490503451.682000.371405.469704.09450K562CELF1
CUL5ENSG00000166266.9960.811701276.12100-0.409403.976502.69720K562DDX3X
CUL5ENSG00000166266.91152.908001401.75730-0.282003.001301.73290K562EIF2S1
CUL5ENSG00000166266.91156.032501729.11690-0.580907.033105.96330K562EIF2S2
CUL5ENSG00000166266.91652.473501211.770400.447403.367202.21860K562EIF3D
CUL5ENSG00000166266.93353.033102807.357400.256203.640302.56530K562EIF4G2
CUL5ENSG00000166266.9887.374801163.80240-0.391203.916702.34190K562EWSR1
CUL5ENSG00000166266.91225.453901559.54030-0.347802.827401.96880K562FIP1L1
CUL5ENSG00000166266.91119.283901469.01250-0.392303.209402.28300K562FMR1
CUL5ENSG00000166266.92228.256801481.084800.589204.128403.22380K562G3BP2
CUL5ENSG00000166266.91575.020802304.43730-0.549004.334803.39290K562GRSF1
CUL5ENSG00000166266.91619.805602114.35750-0.384403.900402.61820K562HNRNPL
CUL5ENSG00000166266.9744.478001282.75180-0.784908.544606.75320K562HNRNPM
CUL5ENSG00000166266.91392.544602114.39490-0.602507.670206.36360K562HSPD1
CUL5ENSG00000166266.91064.937901845.11980-0.7929011.568508.99660K562IGF2BP3
CUL5ENSG00000166266.91112.344801573.95840-0.500808.241106.91480K562MTPAP
CUL5ENSG00000166266.9770.729901114.47000-0.532104.263202.56490K562NONO
CUL5ENSG00000166266.91204.551501770.39770-0.555606.246004.93050K562PPIG
CUL5ENSG00000166266.91384.980401101.142400.330802.456101.74840K562PRPF8
CUL5ENSG00000166266.9718.987501046.07700-0.541003.868302.77240K562PSIP1
CUL5ENSG00000166266.91406.980101786.58140-0.344602.198001.65930K562RBM15
CUL5ENSG00000166266.91070.168601734.93740-0.697003.069301.66400K562SFPQ
CUL5ENSG00000166266.9632.33190904.62690-0.516604.440403.05580K562SRFBP1
CUL5ENSG00000166266.92267.540101816.124400.320203.066302.32510K562SRSF1
CUL5ENSG00000166266.91243.947101838.22470-0.563405.564704.54320K562TARDBP
CUL5ENSG00000166266.91317.746301773.12580-0.428204.460503.38310K562TIA1
CUL5ENSG00000166266.9755.969701006.16950-0.412502.749701.81680K562TIAL1
CUL5ENSG00000166266.91436.953301854.41680-0.368005.500204.52680K562UPF1
CUL5ENSG00000166266.91985.185401649.962200.266703.563802.61020K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CUL5 is not available on ENCORE database.





14 RBPs can affect the splicing of CUL5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECUL5ENSG00000166266.9chr11+1079749161079756291079691321079692561079769331079775790.278000.000000.00001includedK562SRSF1
SECUL5ENSG00000166266.9chr11+107960218107960350107959253107959386107965117107965241-0.107000.000460.01098excludedK562SF3B4
SECUL5ENSG00000166266.9chr11+107974916107975629107969187107969256107976933107977579-0.250000.000060.02237excludedK562WDR3
SECUL5ENSG00000166266.9chr11+107974916107975629107969132107969256107976933107977579-0.452000.000060.00275excludedHepG2HNRNPK
SECUL5ENSG00000166266.9chr11+1079749161079756291079691871079692561079769331079775790.361000.000130.01565includedHepG2TBRG4
SECUL5ENSG00000166266.9chr11+1079749161079756291079691321079692561079769331079775790.281000.000210.01132includedK562FXR1
SECUL5ENSG00000166266.9chr11+107920616107920793107916996107917096107923386107923528-0.154000.006140.09461excludedK562U2AF1
SECUL5ENSG00000166266.9chr11+1079206161079207931079169961079170961079233861079235280.110000.004330.07932includedHepG2SRSF1
SECUL5ENSG00000166266.9chr11+107974916107975629107969132107969256107976933107977579-0.354000.000000.00046excludedK562SRSF7
SECUL5ENSG00000166266.9chr11+107974916107975629107969132107969256107976933107977579-0.418000.000000.00000excludedK562U2AF2
SECUL5ENSG00000166266.9chr11+107974916107975629107969132107969256107976933107977579-0.353000.000000.00003excludedK562HNRNPK
SECUL5ENSG00000166266.9chr11+107974916107975629107969132107969256107976933107977579-0.446000.002190.07707excludedHepG2HNRNPU
A3SSCUL5ENSG00000166266.9chr11+1079430191079431891079430581079431891079407951079409160.053000.009910.05245longerK562AQR
MXECUL5ENSG00000166266.9chr11+1079169961079170961079206161079207931079045271079046371079233861079235280.218000.001490.027661includedK562PUS1
MXECUL5ENSG00000166266.9chr11+1079169371079170961079206161079207931079045271079046371079233861079235280.052000.007960.052611includedK562AQR
MXECUL5ENSG00000166266.9chr11+1079168791079170961079206161079207931079045271079046371079233861079235280.052000.007960.052611includedK562AQR
MXECUL5ENSG00000166266.9chr11+1079169961079170961079206161079207931079045271079046371079233861079235280.374000.002520.017651includedHepG2U2AF2
MXECUL5ENSG00000166266.9chr11+1079169961079170961079206161079207931079045271079046371079233861079235280.372000.000420.044541includedHepG2HNRNPM
MXECUL5ENSG00000166266.9chr11+1079169961079170961079206161079207931079045271079046371079233861079235280.234000.004980.083531includedK562FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CUL5 is not avaliable on ENCORE database.