PSMD6

General Information

Gene Name       : PSMD6
Gene ID             : ENSG00000163636.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PSMD6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PSMD6ENSG00000163636.1075.4171.8273.61ENCSR000AEF
HepG2PSMD6ENSG00000163636.1061.1684.5372.84ENCSR985KAT
K562PSMD6ENSG00000163636.1076.3576.0476.19ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PSMD6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PSMD6 RNA is bound by 20 proteins.  







eCLIP assay for PSMD6 is not avaliable on ENCORE database.





20 proteins are bound to PSMD6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr36399623863996338-3'-UTR,intron-Distal,intron-Proximal4.1535111.58826K562PUM2
chr36399624963996295-3'-UTR,intron-Distal,intron-Proximal4.671054.27202K562PABPC4
chr36400907664009123-5'-UTR,CDS,intron-Distal,intron-Proximal3.975153.48187K562RBM15
chr36400904064009131-5'-UTR,CDS,intron-Distal,intron-Proximal3.6762812.18084HepG2GRWD1
chr36399911463999269-CDS,intron-Distal,intron-Proximal4.371103.25872K562IGF2BP1
chr36400507164005118-CDS,intron-Distal,intron-Proximal3.950115.65086HepG2BCLAF1
chr36400822264008322-CDS,intron-Distal,intron-Proximal3.984243.14375HepG2RBFOX2
chr36400454264004608-CDS,intron-Distal,intron-Proximal3.647173.22245K562GRWD1
chr36400459964004646-CDS,intron-Distal4.665304.78529HepG2BCLAF1
chr36399924863999333-CDS,intron-Distal,intron-Proximal6.4002115.11298K562SF3B4
chr36400800564008125-CDS,intron-Distal3.658373.05347HepG2UCHL5
chr36399924763999317-CDS,intron-Distal,intron-Proximal3.029953.89662K562BUD13
chr36400898664009047-CDS,intron-Distal3.305053.04831K562RBM15
chr36400844064008543-CDS,intron-Distal,intron-Proximal4.254998.49253K562TARDBP
chr36400498664005066-CDS,intron-Distal,intron-Proximal3.938445.79432HepG2BCLAF1
chr36400427264004319-CDS,intron-Distal,intron-Proximal3.418146.00087K562YBX3
chr36400811364008174-CDS,intron-Distal3.363074.48818HepG2GRWD1
chr36400803764008113-CDS,intron-Distal3.527948.31377HepG2GRWD1
chr36400497164005039-CDS,intron-Distal,intron-Proximal4.122533.56019HepG2GRWD1
chr36400508064005138-CDS,intron-Distal,intron-Proximal3.513153.91876HepG2U2AF2
chr36400799364008043-CDS,intron-Distal,intron-Proximal5.176666.58593HepG2BCLAF1
chr36400890464008962-CDS,intron-Distal4.652116.23016HepG2PRPF8
chr36400799364008025-CDS,intron-Distal,intron-Proximal3.414003.05368K562ZNF800
chr36400799364008112-CDS,intron-Distal,intron-Proximal3.7157814.31641K562UCHL5
chr36399967863999771-intron-Distal3.369573.07751K562KHSRP
chr36400819964008272-intron-Distal,intron-Proximal3.360243.86342K562SMNDC1
chr36400876264008796-intron-Distal3.7078425.50404K562TIA1
chr36400016864000300-intron-Distal4.324174.51355HepG2PTBP1
chr36400821164008270-intron-Distal,intron-Proximal5.249156.40247K562SF3B4
chr36400871164008762-intron-Distal3.3703818.67319K562TIA1
chr36400875064008803-intron-Distal4.487575.45972HepG2TIAL1
chr36400874464008803-intron-Distal3.864374.80676K562RBM15
chr36400059764000679-intron-Distal4.393083.92866K562PTBP1
chr36400874164008808-intron-Distal3.196535.96743K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PSMD6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PSMD6 is not available on ENCORE database.

  • 63 RBPs can affect the levels of PSMD6.  








The Knockdown/knockout RNA-Seq assay for PSMD6 is not available on ENCORE database.





63 RBPs can affect the gene expression of PSMD6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PSMD6ENSG00000163636.62397.851601367.256500.810409.441008.52230HepG2AKAP1
PSMD6ENSG00000163636.61332.09530894.481100.574506.328005.46400HepG2BOP1
PSMD6ENSG00000163636.6958.70930779.493300.298502.088601.41090HepG2CALR
PSMD6ENSG00000163636.61931.063601309.748500.560005.444604.59300HepG2DDX3X
PSMD6ENSG00000163636.6865.744001125.05350-0.378002.207801.65020HepG2DDX6
PSMD6ENSG00000163636.6604.476501081.58840-0.839409.405808.35140HepG2EIF2S1
PSMD6ENSG00000163636.61690.477801340.543200.334504.065603.08630HepG2EIF4G1
PSMD6ENSG00000163636.61006.941601284.17630-0.350902.743801.93150HepG2EIF4G2
PSMD6ENSG00000163636.6668.60680930.86670-0.477403.230502.54350HepG2GPKOW
PSMD6ENSG00000163636.6911.757101070.84430-0.232001.979101.36560HepG2HNRNPF
PSMD6ENSG00000163636.6859.826501054.47470-0.294402.304801.64220HepG2IGF2BP1
PSMD6ENSG00000163636.6684.598901105.86800-0.691806.725605.60780HepG2PABPC4
PSMD6ENSG00000163636.61503.66460794.196900.920806.747905.67140HepG2RAVER1
PSMD6ENSG00000163636.62074.438001471.029800.495808.136207.35690HepG2RBM22
PSMD6ENSG00000163636.61008.534701239.26930-0.297202.853602.30600HepG2NELFE
PSMD6ENSG00000163636.6940.316901154.24420-0.295702.885902.25800HepG2RECQL
PSMD6ENSG00000163636.61471.812501052.976200.483003.240102.50970HepG2SF3A3
PSMD6ENSG00000163636.61379.02990978.356200.495102.696801.92540HepG2SNRNP70
PSMD6ENSG00000163636.61923.337801661.465900.211102.384201.90790HepG2SRFBP1
PSMD6ENSG00000163636.6891.229901052.07360-0.239402.017301.41240HepG2SRSF7
PSMD6ENSG00000163636.6712.04850984.49280-0.467406.231505.46260HepG2SRSF9
PSMD6ENSG00000163636.6551.76530733.74090-0.411203.510102.96060HepG2TIAL1
PSMD6ENSG00000163636.6582.78120740.18970-0.344903.194602.59820HepG2TRIM56
PSMD6ENSG00000163636.61296.44340795.142400.705207.967606.90360HepG2U2AF1
PSMD6ENSG00000163636.61280.34030959.833900.415605.445004.01870HepG2UTP18
PSMD6ENSG00000163636.61107.94240901.574100.297303.091302.46460HepG2UTP3
PSMD6ENSG00000163636.62454.590101800.253300.447208.887307.94600K562AGGF1
PSMD6ENSG00000163636.62765.739401873.244700.562007.807006.65810K562AKAP8L
PSMD6ENSG00000163636.62334.439401965.483900.248102.618101.73100K562ATP5C1
PSMD6ENSG00000163636.61343.891801629.24980-0.277803.159902.13740K562BCLAF1
PSMD6ENSG00000163636.6961.894401307.00400-0.442304.591403.58310K562CPSF6
PSMD6ENSG00000163636.61101.039801512.10150-0.457706.866904.92880K562EIF2S1
PSMD6ENSG00000163636.61537.854102230.69840-0.5366010.377509.12110K562EIF2S2
PSMD6ENSG00000163636.61107.645601442.54100-0.381102.301001.36720K562EIF3D
PSMD6ENSG00000163636.6993.261801438.17420-0.534005.787204.60660K562EIF4A3
PSMD6ENSG00000163636.61008.252901329.93120-0.399503.289902.35250K562FMR1
PSMD6ENSG00000163636.61772.306901495.646900.244802.572801.98490K562FXR1
PSMD6ENSG00000163636.6986.801301350.62260-0.452803.483201.86070K562GEMIN5
PSMD6ENSG00000163636.62323.006202972.62100-0.355703.785502.90570K562GRSF1
PSMD6ENSG00000163636.6742.718501251.21780-0.7524010.766109.65270K562HNRNPC
PSMD6ENSG00000163636.62104.919501664.750700.338402.512801.34090K562HNRNPK
PSMD6ENSG00000163636.61982.302702385.42580-0.267102.284601.33450K562HNRNPL
PSMD6ENSG00000163636.61789.874102281.27790-0.350003.084802.24690K562HSPD1
PSMD6ENSG00000163636.62781.295801987.982300.484402.294901.55210K562KIF1C
PSMD6ENSG00000163636.6954.490001218.03800-0.351802.899702.00110K562METAP2
PSMD6ENSG00000163636.61545.712201907.86990-0.303704.155903.18260K562MTPAP
PSMD6ENSG00000163636.61851.616602119.78550-0.195102.710601.97080K562NSUN2
PSMD6ENSG00000163636.62238.583101433.895400.642503.004201.96340K562PABPN1
PSMD6ENSG00000163636.61263.793701582.22150-0.324202.108901.38180K562PCBP3
PSMD6ENSG00000163636.6988.286901213.59980-0.296302.338401.60250K562POLR2G
PSMD6ENSG00000163636.61750.683101310.955300.417203.745002.87220K562PRPF8
PSMD6ENSG00000163636.6828.503201121.84620-0.437303.933802.82810K562PSIP1
PSMD6ENSG00000163636.62948.733403885.86140-0.398107.228805.64780K562PUM2
PSMD6ENSG00000163636.64011.062801857.747801.1103025.6654024.01550K562PUS1
PSMD6ENSG00000163636.62845.781601810.092800.6527014.5400013.16790K562RBM15
PSMD6ENSG00000163636.6935.176601291.50680-0.465703.604402.44440K562RPS3
PSMD6ENSG00000163636.61695.167402091.73090-0.303303.728302.78910K562SF3A3
PSMD6ENSG00000163636.6762.18640970.28120-0.348302.410701.46980K562SRFBP1
PSMD6ENSG00000163636.61862.881402143.02750-0.202102.443101.55760K562SRPK2
PSMD6ENSG00000163636.6896.486001246.94370-0.476004.817103.36720K562SRSF4
PSMD6ENSG00000163636.62699.352603253.24380-0.269302.977901.41350K562SUCLG1
PSMD6ENSG00000163636.6941.809201269.44680-0.430702.951701.90030K562SUPV3L1
PSMD6ENSG00000163636.6749.357601079.02930-0.526004.292003.10750K562TIAL1
PSMD6ENSG00000163636.6893.722101146.32040-0.359102.670401.74460K562TRIM56
PSMD6ENSG00000163636.63445.002304204.14230-0.287302.874101.44280K562UBE2L3
PSMD6ENSG00000163636.61004.911101343.47370-0.418903.227602.12320K562UCHL5
PSMD6ENSG00000163636.61589.282602247.65580-0.5000010.880909.57320K562UPF1
PSMD6ENSG00000163636.6995.783001367.90650-0.458103.748902.26290K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PSMD6 is not available on ENCORE database.





41 RBPs can affect the splicing of PSMD6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.083000.006290.09088excludedK562SRSF1
SEPSMD6ENSG00000163636.6chr3-6400841464008477640079936400819964008950640091320.055000.000560.09360includedK562FTO
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.114000.006390.08919excludedK562SF3B4
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.119000.000290.01436excludedK562PRPF8
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.135000.000010.00694includedK562SMNDC1
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.096000.000000.00113includedK562WDR3
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.074000.000750.02500includedK562AKAP8L
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.110000.000180.02720includedK562FMR1
SEPSMD6ENSG00000163636.6chr3-6400841464008477640079936400819964008950640091320.060000.000010.00452includedK562METAP2
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.092000.000520.00707includedK562AQR
SEPSMD6ENSG00000163636.6chr3-640044936400470564004338640043836400497164005117-0.051000.000000.00002excludedK562AQR
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.127000.000010.00069excludedK562FXR1
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.126000.000000.00005excludedHepG2DDX3X
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.104000.000250.05538includedK562HNRNPA1
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964009067640091340.159000.000400.06061includedK562DROSHA
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.160000.000000.00000includedK562PUS1
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.146000.000000.00000excludedHepG2NCBP2
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.080000.000000.00098includedK562NSUN2
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.110000.001100.05541excludedHepG2PTBP1
SEPSMD6ENSG00000163636.6chr3-6400841464008477640079936400819964008950640091320.052000.000160.04411includedK562GPKOW
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964009067640091340.159000.000480.06733includedK562LARP4
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.159000.000030.03370includedK562SSB
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.116000.000010.00125excludedHepG2MATR3
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.071000.000000.00002excludedHepG2LARP4
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.078000.000010.00143includedK562HNRNPL
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.077000.000510.09982includedK562PPIL4
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.219000.000250.08299excludedHepG2XPO5
SEPSMD6ENSG00000163636.6chr3-640084146400847764007993640081996400895064009132-0.061000.001880.04201excludedHepG2SRSF1
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.121000.000040.00579excludedHepG2IGF2BP3
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.103000.001510.09104excludedHepG2TIAL1
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.101000.000050.00832excludedHepG2SUPV3L1
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.102000.000030.00727includedK562SRSF7
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.148000.000000.00002excludedHepG2SF3B4
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.114000.000030.00212includedK562UTP18
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.057000.000260.04956includedK562UPF1
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.202000.000010.00095includedK562TARDBP
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.131000.000000.00028includedK562HNRNPU
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.072000.001640.03978includedK562RBM15
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.129000.000000.00002includedK562AGGF1
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.091000.001030.09123includedK562CPSF6
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.100000.000600.02705includedK562SF3B1
SEPSMD6ENSG00000163636.6chr3-6400831864008477640079936400819964008950640091480.105000.000010.00415includedK562ZC3H8
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.122000.000390.07733excludedHepG2XRCC6
SEPSMD6ENSG00000163636.6chr3-640083186400847764007993640081996400895064009148-0.105000.000640.07306excludedHepG2KHSRP
SEPSMD6ENSG00000163636.6chr3-6400841464008477640079936400819964008950640091320.060000.002660.04256includedK562HNRNPC
A3SSPSMD6ENSG00000163636.6chr3-6400457464004811640045746400471364004971640050310.075000.000000.00000longerK562AQR
A3SSPSMD6ENSG00000163636.6chr3-6400504864005247640050486400511764007993640091130.100000.000000.00000longerK562AQR
A3SSPSMD6ENSG00000163636.6chr3-640044936400470564004493640046226400497164005031-0.063000.000020.00018shorterK562AQR
MXEPSMD6ENSG00000163636.6chr3-64004971640050316400504864005152640044936400471364007993640091130.058000.000000.000001includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PSMD6 is not avaliable on ENCORE database.