PLEKHB1

General Information

Gene Name       : PLEKHB1
Gene ID             : ENSG00000021300.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PLEKHB1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PLEKHB1ENSG00000021300.130.520.600.56ENCSR000AEF
HepG2PLEKHB1ENSG00000021300.1381.7560.5171.13ENCSR985KAT
K562PLEKHB1ENSG00000021300.130.090.070.08ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PLEKHB1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PLEKHB1 RNA is bound by 10 proteins.  







eCLIP assay for PLEKHB1 is not avaliable on ENCORE database.





10 proteins are bound to PLEKHB1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr117337291573372981+3'-UTR4.218413.27226HepG2IGF2BP3
chr117337318873373301+3'-UTR3.600998.53975HepG2GRSF1
chr117337269073372788+3'-UTR5.678335.16101HepG2PCBP1
chr117337367573373785+3'-UTR4.1279812.93174HepG2PCBP2
chr117337268373372846+3'-UTR4.0368121.33252HepG2PCBP2
chr117337268173372767+3'-UTR3.167317.79183HepG2LARP4
chr117337369773373806+3'-UTR3.3641510.01098HepG2LARP4
chr117337290973373022+3'-UTR3.015434.36071HepG2IGF2BP1
chr117336165373361711+CDS,intron-Distal3.075724.24993HepG2PPIG
chr117337188273371947+CDS,intron-Proximal3.552198.11126HepG2PRPF8
chr117337179273371855+CDS,intron-Proximal3.196224.69671HepG2PPIG
chr117336292773362936+CDS,intron-Proximal5.483138.85296HepG2PPIG
chr117336154073361628+CDS,intron-Distal,intron-Proximal3.958763.25089HepG2AQR
chr117336286273362903+CDS3.4392011.07643HepG2PPIG
chr117336290373362927+CDS4.7133615.40783HepG2PPIG
chr117337180173371892+CDS3.020763.00343HepG2GRWD1
chr117336401773364070+CDS,intron-Proximal4.214039.85077HepG2PPIG
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PLEKHB1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PLEKHB1 is not available on ENCORE database.

  • 129 RBPs can affect the levels of PLEKHB1.  








The Knockdown/knockout RNA-Seq assay for PLEKHB1 is not available on ENCORE database.





129 RBPs can affect the gene expression of PLEKHB1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PLEKHB1ENSG00000021300.91759.978701434.886700.294502.289601.31220HepG2AATF
PLEKHB1ENSG00000021300.9924.339202446.56410-1.4043028.4327026.12060HepG2ABCF1
PLEKHB1ENSG00000021300.9797.943701415.89820-0.8274022.1820020.83310HepG2ACO1
PLEKHB1ENSG00000021300.92292.192401673.233100.454003.345202.25590HepG2ADAR
PLEKHB1ENSG00000021300.91131.183201634.45600-0.531004.178103.54290HepG2AKAP1
PLEKHB1ENSG00000021300.91009.612801422.53130-0.494708.154106.92260HepG2AKAP8L
PLEKHB1ENSG00000021300.92346.810101352.318800.7952010.907309.42420HepG2ASCC1
PLEKHB1ENSG00000021300.9802.300102456.67420-1.6145082.6770079.95190HepG2AUH
PLEKHB1ENSG00000021300.9959.510601364.88430-0.508402.809401.86450HepG2BCCIP
PLEKHB1ENSG00000021300.9403.073602083.31830-2.3698085.7591083.51390HepG2BOP1
PLEKHB1ENSG00000021300.91000.061902425.57520-1.2782040.6234038.42240HepG2CALR
PLEKHB1ENSG00000021300.92133.189503191.71650-0.581304.903803.59260HepG2CCAR1
PLEKHB1ENSG00000021300.91106.254401415.56740-0.355705.388304.51730HepG2CKAP4
PLEKHB1ENSG00000021300.9601.676701042.07540-0.792405.436904.36170HepG2CNOT7
PLEKHB1ENSG00000021300.9707.339801912.62940-1.4351032.9284030.91390HepG2CPSF6
PLEKHB1ENSG00000021300.92914.326902014.761300.532507.651305.90540HepG2CPSF7
PLEKHB1ENSG00000021300.92094.383901715.905000.287503.332302.21510HepG2YBX3
PLEKHB1ENSG00000021300.92014.581502419.85890-0.264403.183302.50360HepG2CELF1
PLEKHB1ENSG00000021300.9766.894802601.91550-1.76250124.60130121.44620HepG2DAZAP1
PLEKHB1ENSG00000021300.9862.422601583.08440-0.8763014.7702013.34740HepG2DDX21
PLEKHB1ENSG00000021300.9656.447901549.19540-1.2388030.3928027.79100HepG2DDX24
PLEKHB1ENSG00000021300.9845.061501255.45770-0.571103.278301.88480HepG2DDX27
PLEKHB1ENSG00000021300.9967.638101565.56450-0.694107.535006.54810HepG2DDX3X
PLEKHB1ENSG00000021300.91429.406702171.92140-0.603603.315602.24770HepG2DDX59
PLEKHB1ENSG00000021300.9494.406301971.33470-1.9954059.4010056.36500HepG2DDX5
PLEKHB1ENSG00000021300.92377.144401345.136500.821409.909908.81930HepG2DDX6
PLEKHB1ENSG00000021300.91277.037901625.03160-0.347702.984101.97070HepG2DHX30
PLEKHB1ENSG00000021300.9471.414301354.62490-1.5228053.3811051.39210HepG2DKC1
PLEKHB1ENSG00000021300.9581.479801684.82020-1.5348056.7270054.11250HepG2DNAJC21
PLEKHB1ENSG00000021300.91357.179001806.58030-0.412703.422502.40450HepG2EEF2
PLEKHB1ENSG00000021300.91987.704701457.810300.447202.990701.83260HepG2AGO1
PLEKHB1ENSG00000021300.9984.065501292.83020-0.393702.748702.15760HepG2EIF2S1
PLEKHB1ENSG00000021300.91021.391201494.98460-0.549607.272505.66340HepG2EIF3G
PLEKHB1ENSG00000021300.9773.951101428.59290-0.8843010.436509.21530HepG2EIF4A3
PLEKHB1ENSG00000021300.91340.385802566.97260-0.9374033.1821030.99360HepG2EIF4G1
PLEKHB1ENSG00000021300.9786.033302458.99130-1.6454047.3663044.61770HepG2EIF4G2
PLEKHB1ENSG00000021300.91455.025202119.31870-0.542606.424904.84210HepG2ESF1
PLEKHB1ENSG00000021300.92205.112602820.67780-0.355206.562505.70210HepG2ETF1
PLEKHB1ENSG00000021300.91081.272701383.56500-0.355703.245902.34210HepG2EWSR1
PLEKHB1ENSG00000021300.91080.652001508.63650-0.481305.288003.78270HepG2FASTKD2
PLEKHB1ENSG00000021300.9623.008001915.84590-1.6207012.2637010.19060HepG2FTO
PLEKHB1ENSG00000021300.9798.982701288.62740-0.689609.513408.10100HepG2FUBP3
PLEKHB1ENSG00000021300.92147.933801441.803300.575006.086405.08570HepG2FXR1
PLEKHB1ENSG00000021300.9896.853601419.96390-0.662907.267405.81200HepG2G3BP2
PLEKHB1ENSG00000021300.9929.058001536.13480-0.725508.740506.92040HepG2GNB2L1
PLEKHB1ENSG00000021300.91080.987902168.19580-1.0041014.9296013.56030HepG2GPKOW
PLEKHB1ENSG00000021300.91716.855701351.763500.344804.873503.61300HepG2HDGF
PLEKHB1ENSG00000021300.9609.61350880.74480-0.530803.114501.66450HepG2HNRNPA0
PLEKHB1ENSG00000021300.91259.197301700.96240-0.433804.335803.55070HepG2HNRNPA1
PLEKHB1ENSG00000021300.92923.783202391.247900.290004.296703.17390HepG2HNRNPA2B1
PLEKHB1ENSG00000021300.91322.792301892.03990-0.516405.944504.95530HepG2HNRNPC
PLEKHB1ENSG00000021300.91442.702401985.94930-0.461108.473207.30670HepG2HNRNPF
PLEKHB1ENSG00000021300.9962.625701354.61090-0.492804.591203.71060HepG2HNRNPK
PLEKHB1ENSG00000021300.91394.620902370.13780-0.7651028.3327026.44620HepG2HNRNPL
PLEKHB1ENSG00000021300.91304.682602069.14180-0.665308.161807.14330HepG2HNRNPLL
PLEKHB1ENSG00000021300.91382.474701704.46880-0.302102.626901.69800HepG2HNRNPM
PLEKHB1ENSG00000021300.91330.573901879.52840-0.498309.927408.83610HepG2HNRNPU
PLEKHB1ENSG00000021300.91140.722701955.58950-0.7777015.5744014.00660HepG2IGF2BP1
PLEKHB1ENSG00000021300.9587.352501359.22520-1.2105019.9009018.27790HepG2IGF2BP2
PLEKHB1ENSG00000021300.9759.862801275.88540-0.747702.420601.50870HepG2IGF2BP3
PLEKHB1ENSG00000021300.92340.459901919.870300.285705.346204.35240HepG2ILF2
PLEKHB1ENSG00000021300.9689.496201015.83050-0.559003.346001.87680HepG2ILF3
PLEKHB1ENSG00000021300.91809.437601367.292800.404102.442201.51140HepG2KHSRP
PLEKHB1ENSG00000021300.91058.898101754.97860-0.728906.469904.56620HepG2KRR1
PLEKHB1ENSG00000021300.9985.032501580.13000-0.681809.268807.15740HepG2LIN28B
PLEKHB1ENSG00000021300.9519.160001442.30850-1.4741027.9303026.00660HepG2MAGOH
PLEKHB1ENSG00000021300.9960.502501274.30670-0.407903.189501.45230HepG2MARK2
PLEKHB1ENSG00000021300.9994.635701999.36870-1.0073022.0871020.09900HepG2MSI2
PLEKHB1ENSG00000021300.91412.688702110.07790-0.578903.824502.67310HepG2MTPAP
PLEKHB1ENSG00000021300.91036.476901360.90480-0.392903.485901.89600HepG2NIP7
PLEKHB1ENSG00000021300.9867.649201664.35130-0.939809.776907.18880HepG2NKRF
PLEKHB1ENSG00000021300.91307.146701834.63090-0.489105.102704.09990HepG2NSUN2
PLEKHB1ENSG00000021300.9415.38380952.31990-1.1970010.008808.28660HepG2PABPC1
PLEKHB1ENSG00000021300.9907.788801321.72390-0.542004.717803.78610HepG2PABPC4
PLEKHB1ENSG00000021300.92011.869801422.210800.5003010.063509.02240HepG2PCBP1
PLEKHB1ENSG00000021300.9391.11830934.41500-1.2565011.665308.85020HepG2PNPT1
PLEKHB1ENSG00000021300.91426.017502098.70250-0.5575012.1516010.69850HepG2PRPF4
PLEKHB1ENSG00000021300.9496.033801034.72160-1.060709.374607.98880HepG2PRPF8
PLEKHB1ENSG00000021300.92189.141201447.198600.5970013.8881012.84640HepG2PTBP1
PLEKHB1ENSG00000021300.91241.820302462.89620-0.9879022.1128020.64380HepG2PUF60
PLEKHB1ENSG00000021300.9895.740302614.48170-1.54540104.86830102.39220HepG2PUM1
PLEKHB1ENSG00000021300.9634.807502612.56660-2.0411095.4190092.13630HepG2PUM2
PLEKHB1ENSG00000021300.91827.475801442.180800.341505.325904.52150HepG2PUS1
PLEKHB1ENSG00000021300.9848.392001567.25390-0.8854018.7056017.28350HepG2QKI
PLEKHB1ENSG00000021300.92217.693701588.860200.481002.355901.70230HepG2RAVER1
PLEKHB1ENSG00000021300.91913.214602272.26840-0.248102.178701.40610HepG2RBM15
PLEKHB1ENSG00000021300.91445.940202357.54650-0.7053016.4866015.43660HepG2RBM22
PLEKHB1ENSG00000021300.92361.029501422.420600.7310013.4576012.03800HepG2RBM25
PLEKHB1ENSG00000021300.9739.464301814.97870-1.2954027.2501024.24510HepG2RBM27
PLEKHB1ENSG00000021300.9536.076101006.32580-0.908608.019705.49900HepG2RBM47
PLEKHB1ENSG00000021300.91359.195601610.55490-0.244802.370501.86270HepG2NELFE
PLEKHB1ENSG00000021300.91868.130701500.082200.316504.327403.57960HepG2RECQL
PLEKHB1ENSG00000021300.9689.856402139.40850-1.6328048.0854046.09260HepG2RPLP0
PLEKHB1ENSG00000021300.9635.539201560.88550-1.2963015.0202013.03030HepG2RPS10
PLEKHB1ENSG00000021300.9844.608801427.01420-0.7566011.7357010.57590HepG2RPS19
PLEKHB1ENSG00000021300.9898.548201673.83790-0.8975014.3191012.60360HepG2RPS2
PLEKHB1ENSG00000021300.91240.886601708.68280-0.461504.596403.19660HepG2RPS5
PLEKHB1ENSG00000021300.91190.235601728.77870-0.538503.243401.58430HepG2RTF1
PLEKHB1ENSG00000021300.9725.330101673.78330-1.2064047.3616045.20680HepG2SAFB2
PLEKHB1ENSG00000021300.9619.97240984.98510-0.667905.338203.51960HepG2SART3
PLEKHB1ENSG00000021300.9639.061001432.23760-1.1642020.4552018.10540HepG2SERBP1
PLEKHB1ENSG00000021300.9734.984801349.23930-0.876408.163406.95980HepG2SF3A3
PLEKHB1ENSG00000021300.91018.378302048.08860-1.0080018.9370017.26350HepG2SF3B1
PLEKHB1ENSG00000021300.91097.593901506.63810-0.457006.987206.11490HepG2SF3B4
PLEKHB1ENSG00000021300.91654.23990822.945301.007202.951401.44340HepG2SFPQ
PLEKHB1ENSG00000021300.91931.815602361.55110-0.289804.852703.96410HepG2SLBP
PLEKHB1ENSG00000021300.91552.44240757.801701.034503.699102.13240HepG2SNRNP200
PLEKHB1ENSG00000021300.91104.312702662.72990-1.2698066.2172064.60490HepG2SRFBP1
PLEKHB1ENSG00000021300.91168.081102203.61690-0.9157010.643108.57610HepG2SRSF3
PLEKHB1ENSG00000021300.91181.535301951.14220-0.7237018.7837017.26370HepG2SRSF7
PLEKHB1ENSG00000021300.9239.097502311.82390-3.27340249.90210247.39780HepG2SSB
PLEKHB1ENSG00000021300.9413.142601650.05010-1.9978035.3963032.07290HepG2STAU1
PLEKHB1ENSG00000021300.9602.72870909.74460-0.594004.177802.79760HepG2STIP1
PLEKHB1ENSG00000021300.91275.027802765.57400-1.1171056.7846054.64940HepG2SUCLG1
PLEKHB1ENSG00000021300.9877.542001771.63070-1.0135011.910909.15890HepG2SUGP2
PLEKHB1ENSG00000021300.9987.698101668.12190-0.7561013.0288011.10550HepG2SUPT6H
PLEKHB1ENSG00000021300.9363.788701335.84460-1.8766016.2090014.81160HepG2SUPV3L1
PLEKHB1ENSG00000021300.91132.602501413.64130-0.319803.217902.61960HepG2TAF15
PLEKHB1ENSG00000021300.91229.998902016.55690-0.7132010.125708.86590HepG2TARDBP
PLEKHB1ENSG00000021300.9900.734601718.87380-0.932305.348703.90490HepG2TBRG4
PLEKHB1ENSG00000021300.9742.045101826.18650-1.2993038.5580037.08920HepG2TIAL1
PLEKHB1ENSG00000021300.9597.026602113.27340-1.8236051.0884048.29660HepG2U2AF1
PLEKHB1ENSG00000021300.91383.396302546.89100-0.8805012.1093010.31290HepG2UBE2L3
PLEKHB1ENSG00000021300.9526.737401196.57240-1.1838035.0029033.09610HepG2UPF1
PLEKHB1ENSG00000021300.9596.904101222.78220-1.034608.053906.29620HepG2UPF2
PLEKHB1ENSG00000021300.9598.192601155.23840-0.9495013.5060012.33200HepG2UTP3
PLEKHB1ENSG00000021300.9522.91900936.86450-0.841307.112005.36070HepG2XPO5
PLEKHB1ENSG00000021300.9800.142502071.21190-1.3721061.4793059.21450HepG2ZC3H8
PLEKHB1ENSG00000021300.9679.144701315.99570-0.9544025.4730024.23500HepG2ZNF622
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PLEKHB1 is not available on ENCORE database.





4 RBPs can affect the splicing of PLEKHB1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPLEKHB1ENSG00000021300.9chr11+7336441473364506733640197336405973371797733718110.105000.004720.07245includedHepG2U2AF1
SEPLEKHB1ENSG00000021300.9chr11+7336441473364506733640197336405973371797733718110.136000.001810.04089includedHepG2SRSF1
MXEPLEKHB1ENSG00000021300.9chr11+73360056733601327336159773361750733586997335878373362832733629350.189000.000210.033971includedHepG2FUS
MXEPLEKHB1ENSG00000021300.9chr11+7336401973364059733717977337189773362832733629357337251073372596-0.166000.000100.018292includedHepG2DDX52

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PLEKHB1 is not avaliable on ENCORE database.