CD74

General Information

Gene Name       : CD74
Gene ID             : ENSG00000019582.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CD74)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CD74ENSG00000019582.142077.483090.922584.20ENCSR000AEF
HepG2CD74ENSG00000019582.14149.4193.75121.58ENCSR985KAT
K562CD74ENSG00000019582.140.790.270.53ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CD74 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CD74 RNA is bound by 11 proteins.  







eCLIP assay for CD74 is not avaliable on ENCORE database.





11 proteins are bound to CD74 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5149781649149781702-3'-UTR,intron-Distal,intron-Proximal3.178136.56927HepG2IGF2BP3
chr5149781466149781516-3'-UTR,intron-Distal3.765503.45687HepG2IGF2BP3
chr5149781789149781813-3'-UTR,CDS,intron-Distal5.028187.76864HepG2SND1
chr5149781248149781311-3'-UTR,intron-Distal,intron-Proximal3.5320817.49553HepG2LARP4
chr5149781239149781301-3'-UTR,intron-Distal,intron-Proximal4.939158.33726HepG2IGF2BP3
chr5149781254149781305-3'-UTR,intron-Distal,intron-Proximal4.110307.39763HepG2PCBP1
chr5149781661149781698-3'-UTR,intron-Distal,intron-Proximal4.956248.64896HepG2PCBP1
chr5149781572149781603-3'-UTR,intron-Distal4.4816215.95793HepG2IGF2BP1
chr5149781649149781698-3'-UTR,intron-Distal,intron-Proximal5.19128400.00000HepG2PCBP2
chr5149781547149781627-3'-UTR,CDS,intron-Distal,intron-Proximal5.0951310.79955HepG2IGF2BP3
chr5149782127149782187-3'-UTR,CDS,intron-Distal4.5172618.26310HepG2SND1
chr5149781379149781441-3'-UTR,intron-Distal,intron-Proximal4.3419454.02765HepG2PCBP2
chr5149781698149781755-3'-UTR,intron-Distal,intron-Proximal4.5861219.54509HepG2PCBP1
chr5149781603149781640-3'-UTR,intron-Distal,intron-Proximal4.7240112.75283HepG2IGF2BP1
chr5149784275149784330-3'-UTR,CDS,intron-Distal5.8593529.43530HepG2SND1
chr5149781314149781377-3'-UTR,intron-Distal,intron-Proximal4.972429.72199HepG2IGF2BP3
chr5149781378149781421-3'-UTR,intron-Distal,intron-Proximal3.9313710.50798HepG2LARP4
chr5149781308149781404-3'-UTR,intron-Distal,intron-Proximal3.5350711.40799HepG2DDX55
chr5149784245149784275-3'-UTR,CDS,intron-Distal4.7867511.23424HepG2SND1
chr5149781281149781301-3'-UTR,intron-Distal6.00229400.00000HepG2PCBP2
chr5149782123149782179-3'-UTR,CDS,intron-Distal,intron-Proximal6.7108512.62434HepG2RPS3
chr5149781311149781359-3'-UTR,intron-Distal,intron-Proximal4.4092215.64631HepG2LARP4
chr5149784660149784743-3'-UTR,CDS,intron-Distal3.9448514.52429HepG2RPS3
chr5149781763149781775-3'-UTR,intron-Distal3.435974.24433HepG2SND1
chr5149781625149781703-3'-UTR,intron-Distal,intron-Proximal5.1608736.39752HepG2LARP4
chr5149785821149785849-3'-UTR,CDS,intron-Distal,intron-Proximal5.2267411.30243HepG2SND1
chr5149785774149785839-3'-UTR,CDS,intron-Distal,intron-Proximal3.9930510.07874HepG2PRPF8
chr5149781532149781599-3'-UTR,CDS,intron-Distal3.178224.35973HepG2DDX55
chr5149784646149784670-3'-UTR,CDS,intron-Distal,intron-Proximal5.4199114.62510HepG2SND1
chr5149781232149781300-3'-UTR,intron-Distal,intron-Proximal4.9625111.20878HepG2ILF3
chr5149781695149781746-3'-UTR,intron-Distal,intron-Proximal3.397707.74172HepG2SND1
chr5149781635149781751-3'-UTR,intron-Distal,intron-Proximal3.0901914.81753HepG2DDX55
chr5149781708149781787-3'-UTR,intron-Distal,intron-Proximal4.7152731.03884HepG2LARP4
chr5149781383149781433-3'-UTR,intron-Distal,intron-Proximal3.890545.73132HepG2ILF3
chr5149781332149781371-3'-UTR,intron-Distal,intron-Proximal5.26430400.00000HepG2PCBP2
chr5149781707149781721-3'-UTR,intron-Distal,intron-Proximal5.25079400.00000HepG2PCBP2
chr5149781359149781378-3'-UTR,intron-Distal,intron-Proximal3.8690810.57046HepG2LARP4
chr5149781301149781312-3'-UTR,intron-Distal5.4980750.19930HepG2PCBP2
chr5149781567149781625-3'-UTR,intron-Distal,intron-Proximal4.3092618.23197HepG2LARP4
chr5149781651149781743-3'-UTR,intron-Distal,intron-Proximal3.045699.47075HepG2ILF3
chr5149781312149781332-3'-UTR,intron-Distal,intron-Proximal5.77584400.00000HepG2PCBP2
chr5149781698149781707-3'-UTR,intron-Distal,intron-Proximal5.29390400.00000HepG2PCBP2
chr5149781540149781572-3'-UTR,CDS,intron-Distal3.520357.34809HepG2IGF2BP1
chr5149784670149784744-3'-UTR,CDS,intron-Distal,intron-Proximal6.5185146.53154HepG2SND1
chr5149781721149781750-3'-UTR,intron-Distal,intron-Proximal4.82596400.00000HepG2PCBP2
chr5149781235149781281-3'-UTR,intron-Distal,intron-Proximal5.45898400.00000HepG2PCBP2
chr5149785863149785884-CDS,intron-Distal4.3571511.78537HepG2SND1
chr5149786443149786522-CDS,intron-Distal,intron-Proximal4.0586318.71568HepG2RPS3
chr5149786725149786755-CDS,intron-Distal3.816384.24433HepG2SND1
chr5149786442149786521-CDS,intron-Distal,intron-Proximal4.8758729.13478HepG2SND1
chr5149786739149786857-CDS,intron-Distal3.042508.87436HepG2DDX3X
chr5149786716149786772-CDS,intron-Distal3.241978.54493HepG2RPS3
chr5149786772149786854-CDS,intron-Distal5.1705420.62869HepG2RPS3
chr5149792186149792244-CDS,intron-Distal4.7163821.10364HepG2RPS3
chr5149792185149792242-CDS,intron-Distal3.9107815.91425HepG2DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CD74 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CD74 is not available on ENCORE database.

  • 131 RBPs can affect the levels of CD74.  








The Knockdown/knockout RNA-Seq assay for CD74 is not available on ENCORE database.





131 RBPs can affect the gene expression of CD74 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CD74ENSG00000019582.10869.465901273.74820-0.550905.837604.33210HepG2AATF
CD74ENSG00000019582.103149.825901251.702701.331305.995504.60140HepG2ADAR
CD74ENSG00000019582.102263.705701627.807100.475703.917702.68230HepG2AKAP8
CD74ENSG00000019582.102218.006001491.442200.5725011.289009.87390HepG2AKAP8L
CD74ENSG00000019582.102634.779101753.887000.587006.450405.27450HepG2ASCC1
CD74ENSG00000019582.101833.705802586.23990-0.4961010.666409.46510HepG2AUH
CD74ENSG00000019582.101959.551901387.243900.498202.445501.56470HepG2BCCIP
CD74ENSG00000019582.102566.543101205.160801.090507.194205.82540HepG2BCLAF1
CD74ENSG00000019582.101540.085102562.42970-0.7345011.7742010.65450HepG2BOP1
CD74ENSG00000019582.103228.090401955.006500.7234013.2690010.79840HepG2BUD13
CD74ENSG00000019582.104810.299602924.277900.717905.592304.18270HepG2CCAR1
CD74ENSG00000019582.104321.051901666.351701.3746034.6447032.39710HepG2CIRBP
CD74ENSG00000019582.102862.681501484.142700.9476045.3067043.39340HepG2CKAP4
CD74ENSG00000019582.101391.28020971.034000.518702.775602.00960HepG2CNOT7
CD74ENSG00000019582.101943.223802352.48320-0.275701.881201.30240HepG2CPSF6
CD74ENSG00000019582.102725.712902148.900200.342903.610002.35040HepG2CPSF7
CD74ENSG00000019582.101973.119601283.606900.620206.210804.68580HepG2YBX3
CD74ENSG00000019582.101365.22720856.539400.672406.278404.75660HepG2CSTF2
CD74ENSG00000019582.103119.395601937.834400.6867014.4063013.16480HepG2CELF1
CD74ENSG00000019582.101140.239302083.41230-0.8696031.0425029.07030HepG2DAZAP1
CD74ENSG00000019582.102175.769401372.924500.6642020.2556018.49880HepG2DDX19B
CD74ENSG00000019582.101920.368701285.394400.5791010.664708.63140HepG2DDX1
CD74ENSG00000019582.102559.315401404.592800.8655016.5827015.09060HepG2DDX21
CD74ENSG00000019582.101875.158701375.113800.447405.406804.12370HepG2DDX24
CD74ENSG00000019582.103080.206402030.410100.601206.674305.74510HepG2DDX3X
CD74ENSG00000019582.102250.983301312.955600.7776011.989409.60450HepG2DDX52
CD74ENSG00000019582.102308.840201364.076800.759106.233805.12860HepG2DDX55
CD74ENSG00000019582.101909.714202671.40650-0.484202.275101.39150HepG2DDX59
CD74ENSG00000019582.102329.689401744.764600.417002.418401.83720HepG2DDX6
CD74ENSG00000019582.101956.715001420.241200.462208.239607.19150HepG2DKC1
CD74ENSG00000019582.103566.568001249.278301.51330118.98650115.46430HepG2DNAJC2
CD74ENSG00000019582.103520.577301566.184101.1685018.7567016.69690HepG2EEF2
CD74ENSG00000019582.102395.395501979.429500.275102.600901.47240HepG2EIF2S2
CD74ENSG00000019582.102466.925601271.200900.9564015.2646013.34550HepG2EIF3D
CD74ENSG00000019582.101299.186101852.64980-0.512003.336602.63600HepG2EIF4A3
CD74ENSG00000019582.103134.201301804.364800.796506.267105.26250HepG2EIF4B
CD74ENSG00000019582.101670.362002055.61700-0.299402.091501.34720HepG2EIF4G1
CD74ENSG00000019582.101102.106601969.11310-0.8373012.9983011.32380HepG2EIF4G2
CD74ENSG00000019582.103176.228902260.345700.490705.140803.69420HepG2ESF1
CD74ENSG00000019582.102460.015702969.46990-0.271502.349301.78770HepG2ETF1
CD74ENSG00000019582.101801.729101136.516800.664707.722905.74810HepG2FAM120A
CD74ENSG00000019582.10906.359601338.84820-0.562806.709805.06900HepG2FASTKD2
CD74ENSG00000019582.103790.327202634.730100.524605.164904.14190HepG2FIP1L1
CD74ENSG00000019582.103534.613002356.446600.584802.303001.38330HepG2FTO
CD74ENSG00000019582.101091.678201729.33760-0.663702.467201.72450HepG2FUBP3
CD74ENSG00000019582.103085.064201526.726201.0148011.755809.68210HepG2FUS
CD74ENSG00000019582.102639.577501131.783301.2216026.3486023.99220HepG2GEMIN5
CD74ENSG00000019582.101748.975401333.061100.391702.507701.54370HepG2GNB2L1
CD74ENSG00000019582.105726.770402666.813601.1025021.0830019.49090HepG2GPKOW
CD74ENSG00000019582.101975.884101237.550800.674906.436103.72680HepG2GRWD1
CD74ENSG00000019582.101975.894301417.244500.479304.784103.53390HepG2HDGF
CD74ENSG00000019582.101206.47790821.809600.553803.438301.90170HepG2HNRNPA0
CD74ENSG00000019582.105048.547601272.476001.9881090.3674087.79220HepG2HNRNPA1
CD74ENSG00000019582.102697.758101914.829200.4944010.978209.34710HepG2HNRNPA2B1
CD74ENSG00000019582.102948.349401757.257800.7465011.7105010.36980HepG2HNRNPK
CD74ENSG00000019582.102318.588101897.757700.288905.304304.39660HepG2HNRNPL
CD74ENSG00000019582.103045.186501817.925900.7441014.9160013.00840HepG2HNRNPM
CD74ENSG00000019582.102936.916601406.038701.0626047.0234044.78660HepG2HNRNPU
CD74ENSG00000019582.102297.246401762.765700.382002.682802.01650HepG2IGF2BP2
CD74ENSG00000019582.101979.188001436.221600.4625011.072809.71330HepG2ILF2
CD74ENSG00000019582.101251.88460925.964300.435002.742701.55770HepG2KHDRBS1
CD74ENSG00000019582.102886.946001773.346400.703006.663405.03220HepG2KHSRP
CD74ENSG00000019582.102222.823901356.991700.7119024.3878021.81050HepG2KIF1C
CD74ENSG00000019582.105062.725903090.521400.712004.453803.39100HepG2LARP4
CD74ENSG00000019582.101907.074001371.211400.475804.582603.01120HepG2LIN28B
CD74ENSG00000019582.101261.895501870.77510-0.568004.185803.38160HepG2MAGOH
CD74ENSG00000019582.102058.705901330.290800.629904.037902.77620HepG2METAP2
CD74ENSG00000019582.104175.496601925.298901.1168020.2528018.64290HepG2NCBP2
CD74ENSG00000019582.101649.581402065.92000-0.324703.453002.60210HepG2NOL12
CD74ENSG00000019582.103265.877901253.221701.381708.854106.85840HepG2NONO
CD74ENSG00000019582.102887.664201038.984101.474604.716402.22900HepG2NUFIP2
CD74ENSG00000019582.102092.041101573.115100.411204.186302.21380HepG2NUP35
CD74ENSG00000019582.101619.52550950.050700.769405.326303.17530HepG2PA2G4
CD74ENSG00000019582.10531.11490887.74620-0.741103.577002.55770HepG2PABPC1
CD74ENSG00000019582.101979.869601391.734600.508409.870608.43700HepG2PARN
CD74ENSG00000019582.103801.246401900.957100.9996045.1089043.21290HepG2PCBP1
CD74ENSG00000019582.102312.937801254.073800.8830019.2635017.45130HepG2PPIL4
CD74ENSG00000019582.102740.659802276.061800.267903.581902.71170HepG2PRPF4
CD74ENSG00000019582.102658.060501518.888100.807306.994405.14380HepG2PRPF6
CD74ENSG00000019582.101726.147001051.587700.714907.076905.85440HepG2PRPF8
CD74ENSG00000019582.102754.986901934.287000.5101011.3315010.37140HepG2PTBP1
CD74ENSG00000019582.103024.997301972.166600.6171010.257909.20780HepG2PUF60
CD74ENSG00000019582.104565.511002093.618301.1247053.7504051.83120HepG2PUM1
CD74ENSG00000019582.101716.350902092.04160-0.285602.608001.95590HepG2PUM2
CD74ENSG00000019582.103518.267701512.036901.2183070.5035068.30000HepG2PUS1
CD74ENSG00000019582.10394.279901393.83100-1.821808.019606.85810HepG2RAVER1
CD74ENSG00000019582.101771.291502415.63030-0.447606.078904.86880HepG2RBM15
CD74ENSG00000019582.102655.53320917.557401.533006.855104.16360HepG2RBM39
CD74ENSG00000019582.10586.93230938.08250-0.676504.093902.24660HepG2RBM47
CD74ENSG00000019582.102382.448801279.098400.8972012.5661010.36240HepG2RCC2
CD74ENSG00000019582.103489.892102152.682300.6969020.2752019.07040HepG2NELFE
CD74ENSG00000019582.101504.728602662.05990-0.8230015.3348013.97550HepG2RPLP0
CD74ENSG00000019582.102561.923401237.126401.0501025.4977023.94260HepG2RPS19
CD74ENSG00000019582.101348.11990975.743000.466302.857102.04420HepG2RPS3A
CD74ENSG00000019582.10943.200501252.13820-0.408806.031605.13550HepG2SAFB2
CD74ENSG00000019582.101784.392201241.345400.523405.090303.82570HepG2SERBP1
CD74ENSG00000019582.104221.179101010.100602.0630011.433908.52580HepG2SF1
CD74ENSG00000019582.103203.086502279.440600.490703.695702.91280HepG2SF3A3
CD74ENSG00000019582.101281.658502519.08080-0.9749018.8861017.21780HepG2SF3B1
CD74ENSG00000019582.102770.88940980.934801.498003.599701.88880HepG2SFPQ
CD74ENSG00000019582.102500.625201891.157100.402908.723807.58820HepG2SLBP
CD74ENSG00000019582.102891.100501460.202400.9854052.4826050.35770HepG2SMN1
CD74ENSG00000019582.102164.650501424.775200.603303.286602.23310HepG2SMNDC1
CD74ENSG00000019582.103286.23170903.488401.8628010.518807.72500HepG2SNRNP200
CD74ENSG00000019582.102181.931302803.17290-0.361507.629706.91180HepG2SRFBP1
CD74ENSG00000019582.103626.317501947.318800.8969037.5523035.61680HepG2SRSF5
CD74ENSG00000019582.102146.544502427.72510-0.177602.077501.46500HepG2SRSF7
CD74ENSG00000019582.101213.526101710.10390-0.494909.564408.64600HepG2SRSF9
CD74ENSG00000019582.102363.745501759.934100.425503.025601.73700HepG2STAU1
CD74ENSG00000019582.102455.395701889.365500.378004.376003.69490HepG2TAF15
CD74ENSG00000019582.103819.571102480.328400.622806.225105.19760HepG2TARDBP
CD74ENSG00000019582.101623.78800909.909400.835505.118403.82420HepG2TFIP11
CD74ENSG00000019582.101083.195401366.22030-0.334901.850101.42320HepG2TIAL1
CD74ENSG00000019582.102125.745001400.628600.601803.348501.74280HepG2TRA2A
CD74ENSG00000019582.102922.989901378.443001.0843048.9689046.97840HepG2TRIM56
CD74ENSG00000019582.103884.566201926.848001.0114013.1152011.01270HepG2TUFM
CD74ENSG00000019582.101749.680802253.90840-0.365302.971002.32110HepG2U2AF1
CD74ENSG00000019582.103707.391901049.959801.820009.246407.32870HepG2U2AF2
CD74ENSG00000019582.10491.22970801.90970-0.707003.567802.70870HepG2UCHL5
CD74ENSG00000019582.103769.849202021.512200.8990041.1571039.13720HepG2UPF1
CD74ENSG00000019582.102754.965502077.855200.406807.253705.64500HepG2UTP18
CD74ENSG00000019582.102733.234301951.695400.4858011.6737010.57810HepG2UTP3
CD74ENSG00000019582.102694.705701533.497600.813206.911105.29930HepG2XRCC6
CD74ENSG00000019582.102437.883801336.530600.8670010.307408.92580HepG2XRN2
CD74ENSG00000019582.1026.638806.879501.953102.795802.13900K562AKAP8L
CD74ENSG00000019582.1036.2107013.201501.455602.283701.56430K562CPSF6
CD74ENSG00000019582.1038.5041013.428601.519602.411001.61050K562FMR1
CD74ENSG00000019582.1039.5648011.380301.797602.430401.57730K562FTO
CD74ENSG00000019582.100.4626012.14250-4.714103.025502.39600K562FXR1
CD74ENSG00000019582.1042.3865012.605701.749403.204102.35190K562GPKOW
CD74ENSG00000019582.1025.432504.031602.657103.061401.40350K562HNRNPAB
CD74ENSG00000019582.1025.635303.093303.050803.895103.20180K562HNRNPC
CD74ENSG00000019582.1017.431702.150803.018702.660401.40380K562NONO
CD74ENSG00000019582.1019.895603.101202.681402.455701.53660K562PABPN1
CD74ENSG00000019582.1036.628203.920103.223905.565603.27010K562SBDS
CD74ENSG00000019582.1022.925502.833203.016303.722802.59440K562TRIM56
CD74ENSG00000019582.1033.1051010.181401.701002.664401.48700K562UTP3
CD74ENSG00000019582.1026.919804.535802.569104.133103.04190K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CD74 is not available on ENCORE database.





9 RBPs can affect the splicing of CD74 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECD74ENSG00000019582.10chr5-149782683149782875149782125149782188149784242149784330-0.073000.002030.03688excludedHepG2U2AF1
SECD74ENSG00000019582.10chr5-149782683149782875149782125149782188149784242149784330-0.139000.000000.00000excludedHepG2HNRNPK
SECD74ENSG00000019582.10chr5-149782683149782875149782125149782188149784242149784330-0.103000.000010.00222excludedHepG2DDX59
SECD74ENSG00000019582.10chr5-1497826831497828751497821251497821881497842421497843300.129000.000080.02054includedHepG2TIA1
SECD74ENSG00000019582.10chr5-1497826831497828751497821251497821881497842421497843300.119000.000120.02821includedHepG2HNRNPA1
SECD74ENSG00000019582.10chr5-1497826831497828751497821251497821881497842421497843300.088000.000150.02347includedHepG2LARP4
SECD74ENSG00000019582.10chr5-1497826831497828751497821251497821881497842421497843300.165000.000000.00008includedHepG2TAF15
SECD74ENSG00000019582.10chr5-1497826831497828751497821251497821881497842421497843300.513000.000000.00000includedHepG2HNRNPU
RICD74ENSG00000019582.10chr5-1497864431497868871497864431497865231497867141497868870.120000.000040.02044includedHepG2HLTF

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CD74 is not avaliable on ENCORE database.