MAT2B

General Information

Gene Name       : MAT2B
Gene ID             : ENSG00000038274.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MAT2B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAT2BENSG00000038274.1647.9342.1045.02ENCSR000AEF
HepG2MAT2BENSG00000038274.1620.4531.2225.84ENCSR985KAT
K562MAT2BENSG00000038274.1636.5034.9235.71ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAT2B is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAT2B RNA is bound by 6 proteins.  







eCLIP assay for MAT2B is not avaliable on ENCORE database.





6 proteins are bound to MAT2B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5162945939162946003+3'-UTR4.3578414.86331K562PUM2
chr5162945581162945615+3'-UTR4.001343.97489K562TIA1
chr5162945852162945904+3'-UTR4.258803.35973HepG2FUBP3
chr5162945873162945939+3'-UTR4.1730120.27594K562PUM2
chr5162946025162946097+3'-UTR3.843767.34677HepG2FUBP3
chr5162945759162945823+3'-UTR3.606376.25768HepG2FUBP3
chr5162932601162932756+5'-UTR,CDS,intron-Distal,intron-Proximal4.4930221.15187K562DDX3X
chr5162939088162939188+CDS,intron-Distal3.096657.04063K562YBX3
chr5162939188162939204+CDS,intron-Distal,intron-Proximal4.134624.31428K562YBX3
chr5162943715162943770+CDS,intron-Proximal4.800453.62536K562AQR
chr5162940602162940668+CDS,intron-Distal3.943113.86978K562YBX3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAT2B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAT2B is not available on ENCORE database.

  • 87 RBPs can affect the levels of MAT2B.  








The Knockdown/knockout RNA-Seq assay for MAT2B is not available on ENCORE database.





87 RBPs can affect the gene expression of MAT2B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAT2BENSG00000038274.12465.75920679.53050-0.545004.473503.14000HepG2AATF
MAT2BENSG00000038274.12617.28940764.59860-0.308802.586401.84190HepG2AKAP8L
MAT2BENSG00000038274.12650.93270902.68910-0.471702.769601.83160HepG2BCCIP
MAT2BENSG00000038274.12821.68640637.702100.365602.088901.41100HepG2CALR
MAT2BENSG00000038274.121583.833601052.901500.589006.089704.97260HepG2CIRBP
MAT2BENSG00000038274.12484.59760760.83200-0.650806.036705.12340HepG2CKAP4
MAT2BENSG00000038274.121356.03980682.755600.989908.428807.11460HepG2CNOT7
MAT2BENSG00000038274.12294.40300430.94140-0.549703.121802.39660HepG2CPSF6
MAT2BENSG00000038274.12529.86280755.13170-0.511105.170003.62350HepG2DDX1
MAT2BENSG00000038274.12579.70860750.18280-0.371902.583401.92440HepG2DDX21
MAT2BENSG00000038274.12666.299401283.03660-0.9453012.1296010.90620HepG2DDX3X
MAT2BENSG00000038274.12662.64840887.52090-0.421502.304401.59270HepG2DDX55
MAT2BENSG00000038274.12285.96260489.36140-0.775103.663302.54170HepG2DDX59
MAT2BENSG00000038274.12856.843901102.16460-0.363202.022101.48660HepG2DDX6
MAT2BENSG00000038274.12555.45820733.88940-0.401904.521803.72320HepG2DNAJC2
MAT2BENSG00000038274.12807.597901059.52800-0.391702.595902.02130HepG2EIF2S1
MAT2BENSG00000038274.12708.46130514.469800.461503.033602.09100HepG2EIF3D
MAT2BENSG00000038274.12511.751301170.89840-1.1941016.4394014.88930HepG2EIF4A3
MAT2BENSG00000038274.12813.240101140.04270-0.487302.804902.11140HepG2EIF4B
MAT2BENSG00000038274.12812.176401285.37530-0.662305.268404.17370HepG2EIF4G1
MAT2BENSG00000038274.12910.90170692.163700.396102.002001.34150HepG2FIP1L1
MAT2BENSG00000038274.12326.67240458.06290-0.487703.152802.18980HepG2GEMIN5
MAT2BENSG00000038274.12487.01110726.58660-0.577204.948103.68040HepG2HDGF
MAT2BENSG00000038274.12409.98810831.50080-1.0201013.5889012.16230HepG2HNRNPC
MAT2BENSG00000038274.12545.60550719.33500-0.398803.824202.99320HepG2HNRNPF
MAT2BENSG00000038274.12360.64990477.49770-0.404902.532301.62100HepG2HNRNPM
MAT2BENSG00000038274.12731.27270989.16090-0.435802.471501.68870HepG2LARP4
MAT2BENSG00000038274.12829.858101181.81390-0.510104.103003.30670HepG2MAGOH
MAT2BENSG00000038274.12350.69910470.33280-0.423402.661201.47040HepG2NAA15
MAT2BENSG00000038274.12362.467401216.41830-1.7467033.7850031.78420HepG2NCBP2
MAT2BENSG00000038274.12665.221901083.29140-0.703506.963305.82420HepG2PABPC4
MAT2BENSG00000038274.12914.172301106.59130-0.275602.703902.10270HepG2PCBP1
MAT2BENSG00000038274.12379.15830612.24640-0.691303.870402.06880HepG2PNPT1
MAT2BENSG00000038274.12487.81510736.73120-0.594806.854105.73470HepG2PPIL4
MAT2BENSG00000038274.12221.51860521.81660-1.2361020.0062018.26210HepG2PRPF4
MAT2BENSG00000038274.12461.031101233.30120-1.4196032.1206030.37470HepG2PUF60
MAT2BENSG00000038274.12698.859201309.18140-0.9056027.3551025.87950HepG2PUM1
MAT2BENSG00000038274.12943.178001308.23900-0.472005.624804.68210HepG2PUM2
MAT2BENSG00000038274.12994.124101219.50860-0.294802.607901.99830HepG2QKI
MAT2BENSG00000038274.12899.38250683.189600.396503.401202.45950HepG2RBM15
MAT2BENSG00000038274.121513.616501224.579300.305603.217702.66990HepG2RBM22
MAT2BENSG00000038274.12561.92730735.59850-0.388503.922703.17810HepG2SAFB2
MAT2BENSG00000038274.12310.04700502.41930-0.696405.176603.89990HepG2SERBP1
MAT2BENSG00000038274.12282.48170676.44140-1.2598012.9431011.42230HepG2SF3A3
MAT2BENSG00000038274.12707.863701182.49800-0.7403016.7171015.25860HepG2SLBP
MAT2BENSG00000038274.12656.86950857.84130-0.385104.566003.77540HepG2SMN1
MAT2BENSG00000038274.12776.85820513.477000.597303.244902.39690HepG2SNRNP70
MAT2BENSG00000038274.121645.006601383.110700.250102.984302.47030HepG2SRFBP1
MAT2BENSG00000038274.121470.909401223.638300.265402.688602.22100HepG2SRSF1
MAT2BENSG00000038274.12584.97790706.73170-0.272802.112901.49530HepG2SRSF7
MAT2BENSG00000038274.12776.99300995.47990-0.357504.118603.47010HepG2SRSF9
MAT2BENSG00000038274.121185.106701384.85890-0.224702.379601.79470HepG2SUCLG1
MAT2BENSG00000038274.12655.91380883.52940-0.429802.369901.73800HepG2SUPV3L1
MAT2BENSG00000038274.12340.61900454.32740-0.415602.116101.47010HepG2TARDBP
MAT2BENSG00000038274.12314.04210802.65160-1.3538027.0868025.81850HepG2TIAL1
MAT2BENSG00000038274.12418.51550809.78990-0.9523018.9483017.64360HepG2TRIM56
MAT2BENSG00000038274.12995.558701204.84670-0.275302.042601.30250HepG2TUFM
MAT2BENSG00000038274.12459.37690592.04170-0.366002.129801.57120HepG2U2AF1
MAT2BENSG00000038274.12476.554401275.28750-1.4201022.2097019.91040HepG2UBE2L3
MAT2BENSG00000038274.12247.49160521.93900-1.0765011.065009.56170HepG2UCHL5
MAT2BENSG00000038274.12448.70100616.61180-0.458604.194902.93830HepG2UTP18
MAT2BENSG00000038274.12648.95990869.73730-0.422502.564201.86520HepG2XRN2
MAT2BENSG00000038274.12645.69550514.961600.326302.736802.06800HepG2ZC3H8
MAT2BENSG00000038274.12111.50550659.77520-2.5649079.5943077.72580HepG2ZNF622
MAT2BENSG00000038274.12541.47770843.10880-0.638804.425802.74930HepG2ZRANB2
MAT2BENSG00000038274.121409.262801020.124000.466106.920606.08150K562AGGF1
MAT2BENSG00000038274.121314.202001820.66900-0.470304.930104.18690K562AQR
MAT2BENSG00000038274.121355.413901113.707300.283302.533401.66150K562ATP5C1
MAT2BENSG00000038274.121495.888201219.155200.295002.475801.37360K562CCDC124
MAT2BENSG00000038274.12763.080201136.04160-0.574103.370701.75900K562CKAP4
MAT2BENSG00000038274.12676.16050910.95440-0.430003.788702.54380K562DDX3X
MAT2BENSG00000038274.121403.966801142.315800.297402.918602.01670K562DKC1
MAT2BENSG00000038274.121317.45060925.379800.509503.931702.67030K562EIF3D
MAT2BENSG00000038274.12710.15650951.72530-0.422403.464702.55030K562EIF4A3
MAT2BENSG00000038274.12469.78540615.95580-0.390802.203201.39170K562FTO
MAT2BENSG00000038274.121390.331901025.280000.439302.728802.02810K562G3BP2
MAT2BENSG00000038274.12474.52190866.47180-0.868709.310806.71770K562GEMIN5
MAT2BENSG00000038274.12409.75480813.54360-0.9895013.7910012.54200K562HNRNPC
MAT2BENSG00000038274.121673.026001316.786900.345302.867602.05780K562HSPD1
MAT2BENSG00000038274.121443.782801126.539500.357902.317401.57090K562KIF1C
MAT2BENSG00000038274.12390.87980582.29710-0.575003.175302.16740K562KRR1
MAT2BENSG00000038274.121070.922301387.74670-0.373903.430402.48930K562MAGOH
MAT2BENSG00000038274.12334.10040665.71300-0.9946012.0821010.17500K562METAP2
MAT2BENSG00000038274.121584.393602064.86080-0.382103.425202.16690K562MSI2
MAT2BENSG00000038274.12604.76540950.35110-0.652108.158006.07790K562NCBP2
MAT2BENSG00000038274.121220.31260841.019700.536905.011504.00550K562PRPF8
MAT2BENSG00000038274.12573.95030729.41800-0.345802.152401.36400K562PSIP1
MAT2BENSG00000038274.121091.632901348.25490-0.304602.595101.94870K562PTBP1
MAT2BENSG00000038274.121601.498902113.63070-0.400303.615702.68550K562PUF60
MAT2BENSG00000038274.121694.269602248.20470-0.408105.448303.90700K562PUM1
MAT2BENSG00000038274.121713.633501052.799000.702709.201308.25990K562PUS1
MAT2BENSG00000038274.121339.811301025.700800.385304.095803.39160K562RBM15
MAT2BENSG00000038274.121150.204701555.27070-0.435304.539502.47960K562RBM17
MAT2BENSG00000038274.121101.63650856.690500.362702.198401.47390K562RPS19
MAT2BENSG00000038274.12330.98290913.92720-1.4653036.4446033.92980K562SF3A3
MAT2BENSG00000038274.121029.857101337.73440-0.377302.909902.18460K562TARDBP
MAT2BENSG00000038274.121062.228801290.37210-0.280702.193701.47230K562TIA1
MAT2BENSG00000038274.12464.12230701.58340-0.596104.450203.24320K562TIAL1
MAT2BENSG00000038274.121004.554001266.02480-0.333802.552001.51050K562TRA2A
MAT2BENSG00000038274.12528.79130745.29260-0.495103.824002.67670K562TRIM56
MAT2BENSG00000038274.121434.36760994.430400.528403.571102.29480K562U2AF1
MAT2BENSG00000038274.121245.514901026.833500.278402.305101.57330K562U2AF2
MAT2BENSG00000038274.121916.011702383.09320-0.314702.904201.46440K562UBE2L3
MAT2BENSG00000038274.12574.89380861.84170-0.584104.960003.55390K562UCHL5
MAT2BENSG00000038274.12644.11600873.83410-0.440005.507404.35430K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAT2B is not available on ENCORE database.





6 RBPs can affect the splicing of MAT2B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMAT2BENSG00000038274.12chr5+162940560162940751162939007162939202162940847162941000-0.070000.000340.00483excludedK562AQR
A3SSMAT2BENSG00000038274.12chr5+1629408261629410001629408471629410001629405731629406750.091000.000000.00003longerK562AQR
A5SSMAT2BENSG00000038274.12chr5+162939007162940675162939007162939202162940847162941000-0.130000.001300.02339shorterK562AQR
RIMAT2BENSG00000038274.12chr5+1629390071629406751629390071629392021629405601629406750.053000.000030.00030includedK562PUS1
RIMAT2BENSG00000038274.12chr5+1629390071629406751629390071629392021629405601629406750.069000.009440.08165includedHepG2SF3A3
RIMAT2BENSG00000038274.12chr5+1629390071629406751629390071629392021629405601629406750.089000.000020.00128includedHepG2UCHL5
RIMAT2BENSG00000038274.12chr5+1629390071629406751629390071629392021629405601629406750.065000.000140.00280includedHepG2NCBP2
RIMAT2BENSG00000038274.12chr5+1629390071629406751629390071629392021629405601629406750.057000.000050.00115includedK562UTP18
MXEMAT2BENSG00000038274.12chr5+162940560162940675162940826162941000162939007162939202162943523162943717-0.097000.011240.069592includedK562AQR
MXEMAT2BENSG00000038274.12chr5+162940560162940675162940800162941000162939007162939202162943523162943717-0.095000.015500.089892includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAT2B is not avaliable on ENCORE database.