PQLC2

General Information

Gene Name       : PQLC2
Gene ID             : ENSG00000040487.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PQLC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PQLC2ENSG00000040487.122.165.003.58ENCSR000AEF
HepG2PQLC2ENSG00000040487.1215.436.6211.03ENCSR985KAT
K562PQLC2ENSG00000040487.1219.2210.9715.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PQLC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PQLC2 RNA is bound by 13 proteins.  







eCLIP assay for PQLC2 is not avaliable on ENCORE database.





13 proteins are bound to PQLC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11965311319653193+3'-UTR,CDS,intron-Proximal4.376694.95909K562BUD13
chr11965276219652838+3'-UTR,CDS3.521255.90680HepG2PPIG
chr11965308619653159+3'-UTR,CDS,intron-Proximal3.249684.69671HepG2PPIG
chr11965276519652863+3'-UTR,CDS3.320673.48584HepG2SND1
chr11965311219653157+3'-UTR,CDS,intron-Proximal4.993247.23427HepG2AQR
chr11965311619653176+3'-UTR,CDS,intron-Proximal5.7404421.23371K562AQR
chr11965563019655718+3'-UTR4.089453.64119HepG2UPF1
chr11965383319653907+3'-UTR,CDS,intron-Distal,intron-Proximal3.291223.30795HepG2SND1
chr11965531619655481+3'-UTR4.077827.60084HepG2UPF1
chr11963922019639270+5'-UTR,intron-Proximal5.867058.23278HepG2DDX3X
chr11963883719638853+5'-UTR,intron-Proximal5.163015.29846HepG2DDX3X
chr11965403519654110+CDS,intron-Distal,intron-Proximal5.693939.42242HepG2PCBP2
chr11963978319639909+intron-Distal5.0170520.65748K562PTBP1
chr11965342319653513+intron-Distal3.530153.80752K562AKAP8L
chr11965344619653512+intron-Distal3.401643.91614K562BUD13
chr11965354719653617+intron-Distal4.471093.31153K562GTF2F1
chr11965343319653520+intron-Distal3.567985.43751K562GTF2F1
chr11963980219639896+intron-Distal4.5912716.31752HepG2PTBP1
chr11965342019653518+intron-Distal4.629085.84605HepG2CSTF2T
chr11965353119653655+intron-Distal,intron-Proximal4.212633.69819HepG2CSTF2T
chr11965344919653515+intron-Distal3.916373.57264HepG2GTF2F1
chr11965343519653510+intron-Distal3.590315.81258K562AQR
chr11965336719653525+intron-Distal5.221609.91068HepG2PRPF4
chr11965311719653178+intron-Proximal4.639915.17894K562PRPF8
chr11965313519653162+intron-Proximal3.262118.72141HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PQLC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PQLC2 is not available on ENCORE database.

  • 121 RBPs can affect the levels of PQLC2.  








The Knockdown/knockout RNA-Seq assay for PQLC2 is not available on ENCORE database.





121 RBPs can affect the gene expression of PQLC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PQLC2ENSG00000040487.8402.82300243.065200.728703.595302.52660HepG2ABCF1
PQLC2ENSG00000040487.8375.06020228.113700.717306.586605.73020HepG2ACO1
PQLC2ENSG00000040487.8453.78760272.632900.735003.690203.08760HepG2AKAP1
PQLC2ENSG00000040487.8296.49690174.674800.763204.308703.01840HepG2AKAP8
PQLC2ENSG00000040487.8380.38000229.159900.731006.567005.43660HepG2AKAP8L
PQLC2ENSG00000040487.8529.88750323.596300.711406.772105.77200HepG2AUH
PQLC2ENSG00000040487.8277.18230170.706300.699202.662701.74520HepG2BCCIP
PQLC2ENSG00000040487.8245.90380148.308400.729402.910701.98710HepG2BCLAF1
PQLC2ENSG00000040487.8299.88580168.027200.835605.321704.52560HepG2BOP1
PQLC2ENSG00000040487.8306.09200214.307500.514202.303401.59290HepG2CIRBP
PQLC2ENSG00000040487.8333.64650228.033400.549003.975203.20500HepG2CKAP4
PQLC2ENSG00000040487.8266.41480119.832401.152606.019704.88900HepG2CNOT7
PQLC2ENSG00000040487.8244.99620154.253000.667403.153302.42430HepG2CPSF6
PQLC2ENSG00000040487.8318.22700200.041100.669703.233502.03610HepG2CPSF7
PQLC2ENSG00000040487.8156.4003095.695600.708602.991001.93060HepG2YBX3
PQLC2ENSG00000040487.8354.16910191.370300.888009.099908.05970HepG2CELF1
PQLC2ENSG00000040487.8301.48130205.685700.551501.989201.34460HepG2DAZAP1
PQLC2ENSG00000040487.8283.89390210.958400.428302.584801.77680HepG2DDX19B
PQLC2ENSG00000040487.8163.1250095.837300.767203.221401.97540HepG2DDX1
PQLC2ENSG00000040487.8595.50780261.128101.1893012.6124011.36770HepG2DDX3X
PQLC2ENSG00000040487.8300.63380167.851200.840703.244002.41600HepG2DDX55
PQLC2ENSG00000040487.8612.61230224.393601.448808.371407.35120HepG2DDX6
PQLC2ENSG00000040487.8305.14700218.235100.483502.716402.04460HepG2DKC1
PQLC2ENSG00000040487.8232.4214093.977501.3063010.799009.48510HepG2DNAJC21
PQLC2ENSG00000040487.8177.2826093.130900.928605.764604.87400HepG2DNAJC2
PQLC2ENSG00000040487.8345.66960215.636400.680703.782203.09610HepG2EIF2S1
PQLC2ENSG00000040487.8288.31070184.289700.645503.213201.94660HepG2EIF2S2
PQLC2ENSG00000040487.8212.22200118.706700.838103.562602.54400HepG2EIF3D
PQLC2ENSG00000040487.8521.25880238.265601.129306.863305.85440HepG2EIF4A3
PQLC2ENSG00000040487.8483.00730371.544000.378402.340701.78010HepG2ETF1
PQLC2ENSG00000040487.8331.82710222.880600.574103.438102.50530HepG2EWSR1
PQLC2ENSG00000040487.8240.69470106.948701.170206.625105.03230HepG2GNB2L1
PQLC2ENSG00000040487.8228.11540101.372401.170006.757604.55860HepG2HNRNPA0
PQLC2ENSG00000040487.8201.1947094.877701.084403.021502.34920HepG2HNRNPA1
PQLC2ENSG00000040487.8163.5157098.987200.724002.707801.32230HepG2HNRNPAB
PQLC2ENSG00000040487.8228.40400105.528301.113902.917502.20730HepG2HNRNPC
PQLC2ENSG00000040487.8327.27640246.929400.406302.379201.71050HepG2HNRNPF
PQLC2ENSG00000040487.8274.36780169.249200.696903.504002.44130HepG2HNRNPM
PQLC2ENSG00000040487.8208.91510104.831000.994806.795705.88390HepG2HNRNPU
PQLC2ENSG00000040487.8532.17800226.706401.2310013.4004012.04000HepG2IGF2BP2
PQLC2ENSG00000040487.8180.79160107.082300.755503.976103.11320HepG2ILF2
PQLC2ENSG00000040487.8198.66190116.830800.765802.926001.55910HepG2ILF3
PQLC2ENSG00000040487.8576.88560215.655701.4195014.7613012.87460HepG2LARP4
PQLC2ENSG00000040487.8196.04820104.824500.903104.093302.70400HepG2LARP7
PQLC2ENSG00000040487.8611.21350240.599501.3449016.1427014.62150HepG2MAGOH
PQLC2ENSG00000040487.8354.47940241.927400.551002.509701.90630HepG2MATR3
PQLC2ENSG00000040487.8359.56730198.502300.857005.941504.79740HepG2MSI2
PQLC2ENSG00000040487.8531.53260247.611001.1020010.265409.08680HepG2NCBP2
PQLC2ENSG00000040487.8298.78860180.193300.729503.540501.91290HepG2NKRF
PQLC2ENSG00000040487.8328.72370203.962000.688502.292201.59800HepG2NOL12
PQLC2ENSG00000040487.8314.48640154.188801.028204.319402.93490HepG2NONO
PQLC2ENSG00000040487.8360.63630109.540101.7190010.408308.65410HepG2PABPC1
PQLC2ENSG00000040487.8399.30190220.443800.857006.213405.14340HepG2PABPC4
PQLC2ENSG00000040487.8154.99110103.771700.578702.219201.45300HepG2PARN
PQLC2ENSG00000040487.8340.92990249.515400.450202.787902.17940HepG2PCBP1
PQLC2ENSG00000040487.8167.9414093.501800.844804.329803.42900HepG2PPIL4
PQLC2ENSG00000040487.8404.45400194.723001.0545010.996709.91460HepG2PUF60
PQLC2ENSG00000040487.8409.70170206.734400.9867013.6137012.50880HepG2PUM1
PQLC2ENSG00000040487.8429.32420206.566401.055402.354901.73480HepG2PUM2
PQLC2ENSG00000040487.8363.77870232.344100.646705.418204.60870HepG2PUS1
PQLC2ENSG00000040487.8231.51440126.996700.866202.180501.54820HepG2RAVER1
PQLC2ENSG00000040487.8613.85700310.539500.9830013.6270012.65190HepG2RBM22
PQLC2ENSG00000040487.8290.54610126.409401.200604.010802.80210HepG2RBM27
PQLC2ENSG00000040487.8215.17760102.650801.067704.941803.51880HepG2RCC2
PQLC2ENSG00000040487.8398.88860265.989700.584502.750702.06920HepG2RPLP0
PQLC2ENSG00000040487.8255.18300115.521101.143308.054507.06980HepG2RPS19
PQLC2ENSG00000040487.8274.51760116.568801.235607.955406.64420HepG2RPS2
PQLC2ENSG00000040487.8224.99320120.370400.902304.292503.29580HepG2RPS3A
PQLC2ENSG00000040487.8276.85620119.006701.218007.843906.04710HepG2RPS5
PQLC2ENSG00000040487.8198.7025093.359901.089607.452306.46910HepG2SAFB2
PQLC2ENSG00000040487.8413.56840260.361100.667503.915003.10710HepG2SF3A3
PQLC2ENSG00000040487.8294.51460165.148200.834503.217802.45980HepG2SF3B1
PQLC2ENSG00000040487.8249.94500186.765200.420302.409601.74870HepG2SLBP
PQLC2ENSG00000040487.8268.94970108.879001.3045012.7210011.49860HepG2SMN1
PQLC2ENSG00000040487.8270.88000129.892901.060206.720605.17250HepG2SMNDC1
PQLC2ENSG00000040487.8578.00160350.738400.720608.414507.67070HepG2SRFBP1
PQLC2ENSG00000040487.8438.33580192.293401.1886017.3178015.94410HepG2SRSF5
PQLC2ENSG00000040487.8435.49440224.469800.9560011.9403010.93600HepG2SRSF9
PQLC2ENSG00000040487.8532.26780304.516200.8055010.020609.16140HepG2SSB
PQLC2ENSG00000040487.8200.72100104.722900.938504.863703.36540HepG2STIP1
PQLC2ENSG00000040487.8456.90910218.662501.0631015.5597014.27740HepG2SUCLG1
PQLC2ENSG00000040487.8332.79510165.612701.006708.435306.85960HepG2SUPT6H
PQLC2ENSG00000040487.8313.25780167.075400.906804.340403.52100HepG2SUPV3L1
PQLC2ENSG00000040487.8131.27360248.01200-0.917806.207105.42450HepG2TAF15
PQLC2ENSG00000040487.8218.66940111.973900.965504.708903.45640HepG2TFIP11
PQLC2ENSG00000040487.8275.38890101.883801.4344011.8334010.92640HepG2TIAL1
PQLC2ENSG00000040487.8298.64750102.772101.5389018.3855017.10140HepG2TRIM56
PQLC2ENSG00000040487.8341.64250190.280800.844303.059002.13540HepG2TUFM
PQLC2ENSG00000040487.8505.14430209.866301.2671012.2831010.92720HepG2U2AF1
PQLC2ENSG00000040487.8303.7893094.031701.691805.654604.19860HepG2U2AF2
PQLC2ENSG00000040487.8444.36340201.438701.141304.477603.39550HepG2UBE2L3
PQLC2ENSG00000040487.8338.93090230.901000.553603.837803.03570HepG2UPF1
PQLC2ENSG00000040487.8272.62420152.942900.833803.190002.11110HepG2UPF2
PQLC2ENSG00000040487.8195.36820107.818300.857503.970802.65360HepG2XPO5
PQLC2ENSG00000040487.8304.74360164.468000.889704.515303.59680HepG2XRN2
PQLC2ENSG00000040487.8228.54370166.946600.453002.183701.57660HepG2ZC3H8
PQLC2ENSG00000040487.8831.92940253.946201.7118054.0443052.41830HepG2ZNF622
PQLC2ENSG00000040487.8175.30180315.91620-0.849706.643405.81900K562AGGF1
PQLC2ENSG00000040487.8235.32320344.89370-0.551503.757802.68090K562ATP5C1
PQLC2ENSG00000040487.8379.22000244.739300.631704.704703.43480K562BCLAF1
PQLC2ENSG00000040487.8265.63820168.493700.656703.563902.09900K562CIRBP
PQLC2ENSG00000040487.8294.68510185.671300.666303.859902.58500K562CSTF2
PQLC2ENSG00000040487.8235.78030353.76380-0.585304.327603.19940K562DKC1
PQLC2ENSG00000040487.8356.16420226.311500.654103.067501.71340K562EEF2
PQLC2ENSG00000040487.8428.74190218.616000.971607.979906.35980K562EFTUD2
PQLC2ENSG00000040487.8231.43190157.692000.553402.573701.80540K562EIF3G
PQLC2ENSG00000040487.8375.44960203.059500.886603.486602.56950K562EIF4A3
PQLC2ENSG00000040487.8481.57170283.486800.764406.549605.20480K562FIP1L1
PQLC2ENSG00000040487.8430.46640211.173101.0274011.6408010.48760K562FXR1
PQLC2ENSG00000040487.829.9418074.35870-1.312302.305601.66800K562G3BP2
PQLC2ENSG00000040487.8417.00380237.414100.812606.340405.47220K562HNRNPC
PQLC2ENSG00000040487.8299.32870212.102700.496902.353301.31470K562HNRNPF
PQLC2ENSG00000040487.8329.50770233.185700.498702.297701.45290K562HNRNPM
PQLC2ENSG00000040487.8237.61700348.87460-0.554102.976002.11890K562KIF1C
PQLC2ENSG00000040487.8319.94820165.226200.953307.964106.50750K562MAGOH
PQLC2ENSG00000040487.8264.00730164.876700.679104.096402.95700K562MATR3
PQLC2ENSG00000040487.8268.70810172.185900.642003.340102.37600K562METAP2
PQLC2ENSG00000040487.8169.77380273.93790-0.690202.953502.03740K562NAA15
PQLC2ENSG00000040487.8238.86470146.993200.700303.600902.48800K562PCBP2
PQLC2ENSG00000040487.8451.30530321.833400.487703.087102.21390K562PPIG
PQLC2ENSG00000040487.8366.52690212.740500.784704.790403.80780K562PRPF8
PQLC2ENSG00000040487.8455.22740160.534601.5036022.1545020.34850K562PTBP1
PQLC2ENSG00000040487.8186.75500326.04310-0.803904.891804.19600K562PUS1
PQLC2ENSG00000040487.8263.18570153.882100.774204.814703.66960K562RBM22
PQLC2ENSG00000040487.8233.37630150.045000.637203.056501.57220K562RBM34
PQLC2ENSG00000040487.8329.56280216.644600.605102.697101.89220K562RPS19
PQLC2ENSG00000040487.8200.2012085.754401.223105.718604.21180K562RPS3
PQLC2ENSG00000040487.8261.26000167.729300.639302.832701.84770K562SF3B1
PQLC2ENSG00000040487.8147.1943077.181800.931304.369203.28590K562SF3B4
PQLC2ENSG00000040487.8613.75590472.217800.378102.603901.69110K562SRPK2
PQLC2ENSG00000040487.8289.41500157.388000.878706.038605.00290K562SRSF1
PQLC2ENSG00000040487.8146.5058082.751400.824002.724101.68560K562SRSF4
PQLC2ENSG00000040487.8215.16070148.667300.533202.316601.36990K562SRSF5
PQLC2ENSG00000040487.897.04730162.66020-0.745103.216401.81390K562SSB
PQLC2ENSG00000040487.8390.02700205.879500.921706.387104.79680K562SUPV3L1
PQLC2ENSG00000040487.8402.81310159.264201.3386014.5314012.65910K562TARDBP
PQLC2ENSG00000040487.8272.04920153.634300.824305.492004.27660K562TIA1
PQLC2ENSG00000040487.8348.63350222.010100.651003.650102.19250K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PQLC2 is not available on ENCORE database.





10 RBPs can affect the splicing of PQLC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPQLC2ENSG00000040487.8chr1+196440931964433519639222196393831965112619651256-0.171000.003050.04722excludedK562HNRNPC
A3SSPQLC2ENSG00000040487.8chr1+1965270219652881196527381965288119651988196520760.093000.004330.02547longerK562AQR
MXEPQLC2ENSG00000040487.8chr1+19639222196393831964409319644335196388191963885219651126196512560.214000.000250.009661includedHepG2MATR3
MXEPQLC2ENSG00000040487.8chr1+1963922219639383196440931964433519638819196388521965112619651256-0.148000.004110.048022includedK562DROSHA
MXEPQLC2ENSG00000040487.8chr1+19639222196393831964409319644335196388191963885219651126196512560.245000.003280.088741includedHepG2SF3B4
MXEPQLC2ENSG00000040487.8chr1+1963922219639383196440931964433519638819196388521965112619651256-0.135000.000110.016042includedK562PUM1
MXEPQLC2ENSG00000040487.8chr1+19639222196393831964409319644335196388191963885219651126196512560.190000.000410.026321includedHepG2DDX3X
MXEPQLC2ENSG00000040487.8chr1+19639222196393831964409319644335196388191963885219651126196512560.300000.000000.000051includedHepG2NCBP2
MXEPQLC2ENSG00000040487.8chr1+19639222196393831964409319644335196388191963885219651126196512560.181000.000460.031471includedHepG2DDX6
MXEPQLC2ENSG00000040487.8chr1+19639222196393831964409319644335196388191963885219651126196512560.231000.002040.042001includedK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PQLC2 is not avaliable on ENCORE database.