HCCS

General Information

Gene Name       : HCCS
Gene ID             : ENSG00000004961.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: HCCS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HCCSENSG00000004961.1424.8726.0025.44ENCSR000AEF
HepG2HCCSENSG00000004961.1424.2530.1827.21ENCSR985KAT
K562HCCSENSG00000004961.1451.3048.6249.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HCCS is not avaliable on ENCORE database.



Proteins bound to RNA
  • HCCS RNA is bound by 3 proteins.  







eCLIP assay for HCCS is not avaliable on ENCORE database.





3 proteins are bound to HCCS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX1114042011140487+3'-UTR4.491284.92383K562FAM120A
chrX1112950011129564+5'-UTR,intron-Proximal4.250608.45138K562DDX3X
chrX1112959211129638+5'-UTR,intron-Proximal4.834983.85934HepG2DDX3X
chrX1113546511135520+CDS3.685666.00726K562YBX3
chrX1113545011135465+CDS3.312953.90824K562YBX3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HCCS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HCCS is not available on ENCORE database.

  • 66 RBPs can affect the levels of HCCS.  








The Knockdown/knockout RNA-Seq assay for HCCS is not available on ENCORE database.





66 RBPs can affect the gene expression of HCCS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HCCSENSG00000004961.10416.09470321.181800.373402.502001.91880HepG2ACO1
HCCSENSG00000004961.10791.12200390.418501.018809.918908.97810HepG2AKAP1
HCCSENSG00000004961.10434.62510322.681400.429603.048102.24700HepG2AKAP8L
HCCSENSG00000004961.10479.44340323.053200.569503.524202.63940HepG2ASCC1
HCCSENSG00000004961.10679.34030532.653300.350802.880102.18210HepG2AUH
HCCSENSG00000004961.10613.22100392.636000.643105.401204.59990HepG2BOP1
HCCSENSG00000004961.10434.66450282.555400.621302.785302.01770HepG2CNOT7
HCCSENSG00000004961.10750.17090479.735900.644908.389207.38500HepG2CELF1
HCCSENSG00000004961.10378.88000282.701900.422402.408801.33030HepG2DDX1
HCCSENSG00000004961.10658.46790374.022800.815907.171106.20820HepG2DDX3X
HCCSENSG00000004961.10123.04190269.67170-1.132107.319005.55310HepG2AGO1
HCCSENSG00000004961.10239.70900341.37260-0.510102.275001.69310HepG2EIF4A3
HCCSENSG00000004961.10397.34530508.89990-0.357002.321901.54320HepG2EIF4G1
HCCSENSG00000004961.10370.03240487.49130-0.397702.160501.43400HepG2EIF4G2
HCCSENSG00000004961.10795.57110611.522000.379503.613802.94110HepG2ETF1
HCCSENSG00000004961.10422.08660313.842000.427402.514901.71790HepG2EWSR1
HCCSENSG00000004961.10144.54840247.38400-0.775204.229803.26840HepG2FUBP3
HCCSENSG00000004961.10348.60090455.06730-0.384502.537101.84940HepG2HNRNPF
HCCSENSG00000004961.10365.45430469.86720-0.362602.572501.92110HepG2HNRNPL
HCCSENSG00000004961.10291.22880448.11410-0.621704.882203.94690HepG2IGF2BP1
HCCSENSG00000004961.10508.59140304.683700.739102.283001.39660HepG2IGF2BP3
HCCSENSG00000004961.10610.88800445.944700.453902.302201.55050HepG2LARP4
HCCSENSG00000004961.10664.14760346.388000.939008.416307.36560HepG2MATR3
HCCSENSG00000004961.10355.14010219.572900.693602.938401.85340HepG2METAP2
HCCSENSG00000004961.10576.39810354.561600.700905.163104.30970HepG2NCBP2
HCCSENSG00000004961.10424.14100321.922800.397702.478901.89720HepG2PCBP1
HCCSENSG00000004961.10376.90510488.26210-0.373502.073301.54600HepG2PUF60
HCCSENSG00000004961.10672.08380328.445101.032906.740405.66470HepG2RAVER1
HCCSENSG00000004961.10727.46170511.126600.509104.988304.34420HepG2RBM22
HCCSENSG00000004961.10319.24840204.140800.645003.962403.23940HepG2RPS19
HCCSENSG00000004961.10568.16220371.290800.613703.839403.03940HepG2SF3A3
HCCSENSG00000004961.10439.12320321.174800.451202.516201.89830HepG2SMN1
HCCSENSG00000004961.10914.50250577.311700.6635011.1297010.30650HepG2SRFBP1
HCCSENSG00000004961.10673.30850355.974300.9194013.0330012.17080HepG2SRSF1
HCCSENSG00000004961.10371.85360482.09350-0.374602.510001.90970HepG2SRSF5
HCCSENSG00000004961.10687.48710548.268200.326402.832102.20470HepG2SUCLG1
HCCSENSG00000004961.10558.74890334.090800.741905.959805.05460HepG2U2AF1
HCCSENSG00000004961.10279.70880202.832000.463502.062801.40700HepG2UCHL5
HCCSENSG00000004961.10505.27170317.905800.668406.684605.82230HepG2UTP3
HCCSENSG00000004961.10528.46160362.143300.545105.758705.04480HepG2ZNF622
HCCSENSG00000004961.10886.11310677.431000.387302.866901.66220K562AARS
HCCSENSG00000004961.10934.36670772.633800.274102.425901.88900K562AGGF1
HCCSENSG00000004961.10996.02340803.965400.308902.183401.60040K562AKAP8L
HCCSENSG00000004961.10604.55460783.68710-0.374402.879602.08140K562CPSF6
HCCSENSG00000004961.101429.072401150.335700.312903.744003.00150K562DDX47
HCCSENSG00000004961.10816.305501214.57210-0.573308.935307.75570K562EIF2S2
HCCSENSG00000004961.10952.25440737.255300.369103.414502.53730K562EIF3G
HCCSENSG00000004961.10482.26750675.87750-0.486903.293002.28830K562FTO
HCCSENSG00000004961.101140.76010681.544400.7430013.2733012.04850K562FXR1
HCCSENSG00000004961.101318.589601618.45560-0.295602.519001.79430K562GRSF1
HCCSENSG00000004961.10522.40720741.10890-0.504504.222103.50120K562HNRNPC
HCCSENSG00000004961.101170.05170780.445600.584105.083403.77810K562HNRNPM
HCCSENSG00000004961.10397.42760638.90700-0.684904.415503.20900K562KRR1
HCCSENSG00000004961.10718.01100867.15810-0.272302.296601.55800K562MTPAP
HCCSENSG00000004961.10903.89860669.942300.432002.386601.58080K562NAA15
HCCSENSG00000004961.10807.91380963.47440-0.254002.478401.76780K562NSUN2
HCCSENSG00000004961.101334.772701077.140400.309302.217101.48560K562PPIG
HCCSENSG00000004961.101048.09330848.926200.304002.373001.75010K562PTBP1
HCCSENSG00000004961.101652.686802048.68340-0.309903.629902.53000K562PUM2
HCCSENSG00000004961.101020.35270797.277800.355802.532002.00720K562PUS1
HCCSENSG00000004961.10950.77520776.856300.291402.379101.82230K562RBM15
HCCSENSG00000004961.10755.34250588.105200.361002.884402.01020K562SF3B4
HCCSENSG00000004961.10431.11220574.79470-0.415002.523201.55520K562SRFBP1
HCCSENSG00000004961.10896.32840687.315800.383003.265602.37430K562SYNCRIP
HCCSENSG00000004961.10473.64930679.07940-0.519804.139202.93460K562TRIM56
HCCSENSG00000004961.10815.21440548.281100.572204.316902.88740K562U2AF1
HCCSENSG00000004961.10747.24690566.161500.400303.386902.50080K562U2AF2
HCCSENSG00000004961.10720.110701021.59360-0.504507.287106.18690K562UPF1
HCCSENSG00000004961.10690.94010874.14340-0.339302.509701.67340K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HCCS is not available on ENCORE database.





6 RBPs can affect the splicing of HCCS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHCCSENSG00000004961.10chrX+111390261113911311136620111367401113973111139999-0.079000.000240.00652excludedK562SF3B4
SEHCCSENSG00000004961.10chrX+111390261113911311136620111367401113973111139999-0.065000.000120.00683excludedK562PRPF8
SEHCCSENSG00000004961.10chrX+111390261113911311136620111367401113973111139999-0.090000.000000.00000excludedK562AQR
SEHCCSENSG00000004961.10chrX+111390261113911311136620111367401113973111139999-0.051000.000490.02188excludedK562TARDBP
SEHCCSENSG00000004961.10chrX+111390261113911311136620111367401113973111139999-0.188000.000080.00511excludedK562SF3B1
A5SSHCCSENSG00000004961.10chrX+1113902611139152111390261113911311139731111399990.089000.000700.02870longerK562PUS1
A5SSHCCSENSG00000004961.10chrX+1113902611139152111390261113911311139731111411980.066000.000590.05678longerK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HCCS is not avaliable on ENCORE database.