CTPS2

General Information

Gene Name       : CTPS2
Gene ID             : ENSG00000047230.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CTPS2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CTPS2ENSG00000047230.1412.1410.2011.17ENCSR000AEF
HepG2CTPS2ENSG00000047230.149.9617.1213.54ENCSR985KAT
K562CTPS2ENSG00000047230.149.079.939.50ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CTPS2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CTPS2 RNA is bound by 12 proteins.  







eCLIP assay for CTPS2 is not avaliable on ENCORE database.





12 proteins are bound to CTPS2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX1660729216607437-3'-UTR,intron-Distal4.261439.37242K562UPF1
chrX1672102716721088-5'-UTR,intron-Distal,intron-Proximal3.774934.36528HepG2U2AF2
chrX1662767216627728-CDS,intron-Distal5.5127123.86441HepG2PRPF8
chrX1662763216627672-CDS,intron-Distal,intron-Proximal7.4896621.52046HepG2PRPF8
chrX1671636516716460-CDS,intron-Distal,intron-Proximal4.322827.09561HepG2BCLAF1
chrX1662762716627672-CDS,intron-Distal,intron-Proximal3.745667.75444K562PRPF8
chrX1671708316717135-CDS,intron-Distal3.252664.56058HepG2BCLAF1
chrX1670966316709738-CDS,intron-Distal3.983074.01763HepG2GRWD1
chrX1669652716696576-CDS,intron-Distal,intron-Proximal4.231355.20626K562PUM2
chrX1668563616685678-CDS,intron-Distal,intron-Proximal3.080343.55800HepG2BCLAF1
chrX1662766016627761-CDS,intron-Distal,intron-Proximal3.385564.65365HepG2GRWD1
chrX1668563616685680-CDS,intron-Distal,intron-Proximal3.270003.32039HepG2PPIG
chrX1671704316717083-CDS,intron-Distal,intron-Proximal3.950115.65086HepG2BCLAF1
chrX1661941816619508-intron-Distal3.580613.68481HepG2HNRNPM
chrX1668633416686383-intron-Distal3.608615.07626HepG2PTBP1
chrX1662721716627310-intron-Distal3.882123.89294K562KHSRP
chrX1662310716623178-intron-Distal4.322323.30440HepG2QKI
chrX1661322316613320-intron-Distal4.278415.08344K562TARDBP
chrX1662304916623100-intron-Distal3.952553.05187HepG2QKI
chrX1667254416672605-intron-Distal4.776545.58765HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CTPS2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CTPS2 is not available on ENCORE database.

  • 64 RBPs can affect the levels of CTPS2.  








The Knockdown/knockout RNA-Seq assay for CTPS2 is not available on ENCORE database.





64 RBPs can affect the gene expression of CTPS2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CTPS2ENSG00000047230.10839.15250671.070500.322402.920602.13320HepG2AKAP8L
CTPS2ENSG00000047230.10518.44830848.45440-0.710603.932303.00260HepG2ASCC1
CTPS2ENSG00000047230.10660.39380835.76850-0.339802.153001.62000HepG2BOP1
CTPS2ENSG00000047230.10424.29780635.01300-0.581705.593103.99880HepG2DDX1
CTPS2ENSG00000047230.10451.33170843.59660-0.902405.857804.98880HepG2DDX6
CTPS2ENSG00000047230.10498.16370622.66680-0.321802.319101.66930HepG2DNAJC21
CTPS2ENSG00000047230.10468.59130617.16640-0.397303.824403.08230HepG2DNAJC2
CTPS2ENSG00000047230.10398.00730896.60220-1.171707.469106.41770HepG2EIF4A3
CTPS2ENSG00000047230.10648.37840904.27920-0.479902.352701.71260HepG2FXR1
CTPS2ENSG00000047230.10607.92480839.03820-0.464802.111101.52690HepG2G3BP1
CTPS2ENSG00000047230.10340.89740486.54360-0.513202.389501.35380HepG2GRSF1
CTPS2ENSG00000047230.10492.79050628.63210-0.351202.068901.50080HepG2HNRNPA1
CTPS2ENSG00000047230.10440.81190699.23630-0.665606.021705.02710HepG2HNRNPC
CTPS2ENSG00000047230.10679.88460853.29270-0.327802.778802.06030HepG2HNRNPF
CTPS2ENSG00000047230.10743.59420888.63620-0.257101.928601.35320HepG2HNRNPL
CTPS2ENSG00000047230.10527.21720694.61340-0.397803.769303.07260HepG2HNRNPU
CTPS2ENSG00000047230.10582.39050840.25540-0.528805.220404.25890HepG2IGF2BP1
CTPS2ENSG00000047230.10562.06950852.93040-0.601702.793302.11560HepG2IGF2BP2
CTPS2ENSG00000047230.10560.26740709.52470-0.340703.282602.48990HepG2ILF2
CTPS2ENSG00000047230.10784.229401131.40180-0.528802.449801.67120HepG2LARP4
CTPS2ENSG00000047230.10550.76660904.59330-0.715804.089303.29420HepG2MAGOH
CTPS2ENSG00000047230.10643.59840931.18970-0.532902.630602.01190HepG2NCBP2
CTPS2ENSG00000047230.10800.35590967.24630-0.273202.187101.50790HepG2NOL12
CTPS2ENSG00000047230.10551.56300829.50070-0.588702.729102.01200HepG2PABPC4
CTPS2ENSG00000047230.10661.30200859.46850-0.378103.903403.20830HepG2PCBP1
CTPS2ENSG00000047230.10463.32630619.53980-0.419203.532402.71000HepG2PPIL4
CTPS2ENSG00000047230.10349.52380476.34240-0.446602.107801.39810HepG2PRPF8
CTPS2ENSG00000047230.10729.43680923.25570-0.339902.242401.69740HepG2PUF60
CTPS2ENSG00000047230.10798.13360980.00000-0.296202.691402.10480HepG2PUM1
CTPS2ENSG00000047230.10717.30280979.33180-0.449204.569303.71870HepG2PUM2
CTPS2ENSG00000047230.10691.87030947.15730-0.453104.594303.81910HepG2QKI
CTPS2ENSG00000047230.101340.903101016.983500.398804.539303.91850HepG2RBM22
CTPS2ENSG00000047230.10558.97800859.60040-0.620906.719905.71000HepG2RBM25
CTPS2ENSG00000047230.10666.12890919.12080-0.464503.687902.91770HepG2RPLP0
CTPS2ENSG00000047230.10462.68300693.96540-0.584803.205802.19080HepG2RPS10
CTPS2ENSG00000047230.10475.18290618.58440-0.380503.369302.67040HepG2SAFB2
CTPS2ENSG00000047230.10599.13650821.63700-0.455603.372402.60070HepG2SF3B1
CTPS2ENSG00000047230.10636.39070910.51570-0.516806.521205.67620HepG2SF3B4
CTPS2ENSG00000047230.10705.29030885.10080-0.327603.032002.30230HepG2SLBP
CTPS2ENSG00000047230.10745.84970950.37620-0.349603.457702.94440HepG2SRSF1
CTPS2ENSG00000047230.10594.69890784.92780-0.400403.197802.30390HepG2TIA1
CTPS2ENSG00000047230.10525.99110674.94930-0.359702.651402.16000HepG2TIAL1
CTPS2ENSG00000047230.10514.98630680.98010-0.403103.795103.15700HepG2TRIM56
CTPS2ENSG00000047230.10412.14630661.66010-0.682908.301807.35430HepG2UTP3
CTPS2ENSG00000047230.10449.61010605.03030-0.428302.151401.50550HepG2XRN2
CTPS2ENSG00000047230.10600.288401010.37380-0.7512012.8098011.68580K562AGGF1
CTPS2ENSG00000047230.10678.893101095.59370-0.690507.443806.55690K562AQR
CTPS2ENSG00000047230.10698.50140931.20540-0.414802.570101.33730K562CIRBP
CTPS2ENSG00000047230.10398.51480645.30230-0.695306.006704.61870K562EFTUD2
CTPS2ENSG00000047230.10666.04270821.62030-0.302902.052001.41640K562EIF2S2
CTPS2ENSG00000047230.10461.74020691.02920-0.581703.700102.48800K562EIF3D
CTPS2ENSG00000047230.10497.88160655.81760-0.397503.227602.37090K562EIF3G
CTPS2ENSG00000047230.10383.05970715.92580-0.902209.761708.21040K562EIF4A3
CTPS2ENSG00000047230.10664.65570831.94300-0.323902.055201.32090K562FIP1L1
CTPS2ENSG00000047230.10505.64780744.52650-0.558206.433605.56690K562FXR1
CTPS2ENSG00000047230.10716.893701095.01020-0.611104.803003.80860K562GRSF1
CTPS2ENSG00000047230.10472.77590685.38950-0.535804.435803.69810K562HNRNPC
CTPS2ENSG00000047230.10591.51930913.11700-0.626404.679403.57950K562MAGOH
CTPS2ENSG00000047230.10631.86070864.39160-0.452105.221004.13370K562MTPAP
CTPS2ENSG00000047230.10560.86780812.53230-0.534804.252903.03510K562PCBP2
CTPS2ENSG00000047230.10742.04660944.40690-0.347902.351601.59650K562PPIG
CTPS2ENSG00000047230.10317.74780627.95070-0.982809.910708.48500K562PRPF8
CTPS2ENSG00000047230.10448.42460614.53010-0.454602.726001.82970K562PSIP1
CTPS2ENSG00000047230.10634.21740887.11590-0.484103.398002.67070K562PTBP1
CTPS2ENSG00000047230.101265.125301575.22520-0.316302.667401.86580K562PUF60
CTPS2ENSG00000047230.10672.93630850.89040-0.338502.038101.32150K562RBM22
CTPS2ENSG00000047230.10332.95600560.71120-0.751907.429005.79560K562RCC2
CTPS2ENSG00000047230.10752.78660947.67880-0.332202.951602.11150K562SF3A3
CTPS2ENSG00000047230.10476.95340798.88890-0.744109.780508.12340K562SF3B4
CTPS2ENSG00000047230.10800.06000970.91540-0.279202.705401.77800K562SRPK2
CTPS2ENSG00000047230.10309.87440869.61750-1.4887019.3026017.44520K562SRSF1
CTPS2ENSG00000047230.10383.61040608.12940-0.664704.685603.33590K562SUPV3L1
CTPS2ENSG00000047230.10641.24400880.22130-0.457002.936802.20810K562TARDBP
CTPS2ENSG00000047230.10603.55870849.04350-0.492303.938502.93820K562TIA1
CTPS2ENSG00000047230.10627.25060832.89990-0.409102.971401.83050K562TRA2A
CTPS2ENSG00000047230.10555.817601004.49750-0.853808.967806.92620K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CTPS2 is not available on ENCORE database.





3 RBPs can affect the splicing of CTPS2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECTPS2ENSG00000047230.10chrX-166887021668879716685784166858471669648416696573-0.216000.000040.00158excludedK562SRSF1
SECTPS2ENSG00000047230.10chrX-166088741660898516606428166078981662766316627808-0.106000.001580.05345excludedK562TARDBP
SECTPS2ENSG00000047230.10chrX-166088741660898516606428166078981662766316627808-0.090000.000540.02372excludedK562HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CTPS2 is not avaliable on ENCORE database.