TIMP2

General Information

Gene Name       : TIMP2
Gene ID             : ENSG00000035862.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TIMP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TIMP2ENSG00000035862.120.000.000.00ENCSR000AEF
HepG2TIMP2ENSG00000035862.1218.8616.5517.70ENCSR985KAT
K562TIMP2ENSG00000035862.120.000.010.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TIMP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TIMP2 RNA is bound by 14 proteins.  







eCLIP assay for TIMP2 is not avaliable on ENCORE database.





14 proteins are bound to TIMP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr177685003676850111-3'-UTR,intron-Distal6.2712121.48126HepG2AKAP1
chr177685003776850119-3'-UTR,intron-Distal6.4757523.54094HepG2UPF1
chr177685011176850207-3'-UTR,intron-Distal5.0897424.86308HepG2AKAP1
chr177684918776849249-3'-UTR,intron-Distal4.034993.16434HepG2LARP4
chr177685115676851292-3'-UTR,intron-Distal5.4456244.59539HepG2AKAP1
chr177684989976849977-3'-UTR,intron-Distal5.713019.97572HepG2IGF2BP1
chr177685092376850986-3'-UTR,intron-Distal4.6743215.97569HepG2FAM120A
chr177685071276850756-3'-UTR,intron-Distal5.8547514.27099HepG2AKAP1
chr177685109276851127-3'-UTR,intron-Distal6.1267415.83819HepG2AKAP1
chr177685187676851922-3'-UTR,CDS,intron-Distal4.109228.91885HepG2SND1
chr177685154476851623-3'-UTR,intron-Distal,intron-Proximal5.2894039.48830HepG2AKAP1
chr177685139576851432-3'-UTR,intron-Distal4.345476.90648HepG2FAM120A
chr177685002976850101-3'-UTR,intron-Distal3.189157.03858HepG2FAM120A
chr177685175476851869-3'-UTR,CDS,intron-Distal3.6907511.45975HepG2SND1
chr177685141476851447-3'-UTR,intron-Distal4.7465712.68573HepG2AKAP1
chr177685151876851594-3'-UTR,intron-Distal,intron-Proximal4.5344719.98666HepG2FAM120A
chr177685011376850201-3'-UTR,intron-Distal3.279615.93919HepG2FAM120A
chr177685089376850993-3'-UTR,intron-Distal5.3662539.64043HepG2UPF1
chr177685115176851325-3'-UTR,intron-Distal6.0761153.24150HepG2UPF1
chr177685154676851625-3'-UTR,intron-Distal,intron-Proximal,polyA_site6.7779159.97514HepG2UPF1
chr177685140476851546-3'-UTR,intron-Distal,intron-Proximal7.03244106.07446HepG2UPF1
chr177684948576849589-3'-UTR,intron-Distal3.977057.45151HepG2LIN28B
chr177685166676851738-3'-UTR,intron-Distal4.869396.37221HepG2LARP4
chr177685084376850899-3'-UTR,intron-Distal5.4854424.72026HepG2AKAP1
chr177685012876850183-3'-UTR,intron-Distal4.3151813.41308HepG2UPF1
chr177685121876851280-3'-UTR,intron-Distal4.0865113.60331HepG2FAM120A
chr177685107476851118-3'-UTR,intron-Distal5.6808911.18590HepG2FAM120A
chr177685033976850421-3'-UTR,intron-Distal5.7268528.97087HepG2LIN28B
chr177685144776851544-3'-UTR,intron-Distal,intron-Proximal6.0496252.39456HepG2AKAP1
chr177685078976850832-3'-UTR,intron-Distal3.705838.03852HepG2FAM120A
chr177685192276851947-3'-UTR,CDS,intron-Distal,intron-Proximal3.596944.95361HepG2SND1
chr177685089976850983-3'-UTR,intron-Distal5.3000328.90570HepG2AKAP1
chr177685078076850843-3'-UTR,intron-Distal6.6993728.19888HepG2AKAP1
chr177685078476850844-3'-UTR,intron-Distal5.2590218.32365HepG2UPF1
chr177685145276851518-3'-UTR,intron-Distal3.045019.27088HepG2FAM120A
chr177685116976851218-3'-UTR,intron-Distal5.3289115.66890HepG2FAM120A
chr177692113876921181-5'-UTR,CDS,intron-Distal3.570793.91829HepG2DDX3X
chr177692119376921327-5'-UTR,intron-Distal4.9388621.94029HepG2DDX3X
chr177692121476921325-5'-UTR,intron-Distal3.7844111.45770HepG2RPS3
chr177686697976866990-CDS,intron-Distal,intron-Proximal4.813425.84094HepG2SND1
chr177686699776867066-CDS,intron-Distal3.8054810.65426HepG2SND1
chr177685362876853688-CDS,intron-Distal3.6973116.46471HepG2SND1
chr177692107276921138-CDS,intron-Distal3.8787212.20639HepG2DDX3X
chr177685368876853730-CDS,intron-Distal,intron-Proximal3.392048.47810HepG2SND1
chr177688962776889748-intron-Distal4.391923.57264HepG2GTF2F1
chr177692045176920551-intron-Distal3.647824.14880HepG2CSTF2T
chr177688962876889681-intron-Distal5.577679.44554HepG2HNRNPL
chr177688943976889451-intron-Distal4.539343.33101HepG2AGGF1
chr177688968976889765-intron-Distal4.101368.12378HepG2AGGF1
chr177688907176889170-intron-Distal3.516724.00486HepG2HNRNPL
chr177688961676889689-intron-Distal5.0902612.79445HepG2AGGF1
chr177688912676889277-intron-Distal3.5409310.10531HepG2XPO5
chr177688961976889665-intron-Distal3.704313.60408HepG2XPO5
chr177688920976889285-intron-Distal3.884567.66211HepG2AGGF1
chr177691684876916908-intron-Distal4.446608.47823HepG2XPO5
chr177688928576889388-intron-Distal4.717238.13412HepG2AGGF1
chr177688968176889762-intron-Distal5.2464313.02798HepG2HNRNPL
chr177689310976893179-intron-Distal3.321253.69530HepG2CSTF2T
chr177688915376889209-intron-Distal3.611315.66406HepG2AGGF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TIMP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TIMP2 is not available on ENCORE database.

  • 141 RBPs can affect the levels of TIMP2.  








The Knockdown/knockout RNA-Seq assay for TIMP2 is not available on ENCORE database.





141 RBPs can affect the gene expression of TIMP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TIMP2ENSG00000035862.81988.487301054.435600.9151016.7507014.45350HepG2AATF
TIMP2ENSG00000035862.8855.352901738.10770-1.0229014.2829012.42680HepG2ABCF1
TIMP2ENSG00000035862.84482.347601142.990001.97130134.67250132.10080HepG2ACO1
TIMP2ENSG00000035862.81815.559701347.337300.430202.342801.42310HepG2ADAR
TIMP2ENSG00000035862.84021.75160901.351002.1576059.6858057.72970HepG2AKAP1
TIMP2ENSG00000035862.86296.882601853.032001.7646048.0770044.65850HepG2AKAP8
TIMP2ENSG00000035862.82867.158001148.513201.3198064.2905061.44220HepG2AKAP8L
TIMP2ENSG00000035862.82174.24720745.757101.5436035.0512032.75770HepG2ASCC1
TIMP2ENSG00000035862.85319.765401576.311001.75470135.18830131.90510HepG2AUH
TIMP2ENSG00000035862.82085.063301302.266800.6790010.658408.40290HepG2BUD13
TIMP2ENSG00000035862.82536.774601478.653400.7786017.0255015.41140HepG2CALR
TIMP2ENSG00000035862.81891.160301142.925700.7264022.3885020.90230HepG2CKAP4
TIMP2ENSG00000035862.81853.031202819.78940-0.605704.001803.07510HepG2CNOT7
TIMP2ENSG00000035862.82145.291501431.417400.583608.443806.61960HepG2CPSF7
TIMP2ENSG00000035862.8554.524201381.65930-1.3171038.2866035.10320HepG2YBX3
TIMP2ENSG00000035862.81531.610401079.365300.504803.290501.76770HepG2CSTF2T
TIMP2ENSG00000035862.88982.956701636.036002.45690246.23080242.45560HepG2CELF1
TIMP2ENSG00000035862.82190.696601759.256800.316305.327204.34380HepG2DAZAP1
TIMP2ENSG00000035862.81952.323901383.620900.496607.935206.11250HepG2DDX1
TIMP2ENSG00000035862.83967.08810863.350502.2000072.0304069.23480HepG2DDX3X
TIMP2ENSG00000035862.81542.65940975.567300.661009.617807.39340HepG2DDX52
TIMP2ENSG00000035862.82189.740601132.011600.9518012.9093011.39000HepG2DDX55
TIMP2ENSG00000035862.85102.751902918.530500.805903.759602.62600HepG2DDX59
TIMP2ENSG00000035862.81853.594701500.571800.304702.255601.34180HepG2DDX5
TIMP2ENSG00000035862.84082.21260741.813802.4601076.4658074.00310HepG2DDX6
TIMP2ENSG00000035862.8634.242501093.57930-0.7860012.5657011.33770HepG2DKC1
TIMP2ENSG00000035862.82696.358601356.733800.9908033.0863030.96150HepG2DNAJC21
TIMP2ENSG00000035862.81650.580801163.824000.504004.542203.38650HepG2EEF2
TIMP2ENSG00000035862.81425.46750970.080600.555205.403703.84800HepG2EFTUD2
TIMP2ENSG00000035862.81644.604301071.418300.618104.995103.50420HepG2AGO1
TIMP2ENSG00000035862.82202.46270712.947101.6272038.1502036.12360HepG2EIF2S1
TIMP2ENSG00000035862.82114.278701318.537800.6811011.535209.37680HepG2EIF2S2
TIMP2ENSG00000035862.84028.33150767.201702.3924057.6737054.94690HepG2EIF4B
TIMP2ENSG00000035862.81156.538401735.51460-0.5856012.0567010.55370HepG2EIF4G1
TIMP2ENSG00000035862.81269.378901662.52990-0.389303.422702.52310HepG2EIF4G2
TIMP2ENSG00000035862.81002.865901505.67100-0.586306.519804.92620HepG2ESF1
TIMP2ENSG00000035862.83668.109401809.745001.0192044.7401042.87440HepG2ETF1
TIMP2ENSG00000035862.82951.765501117.068901.4018016.0090014.10340HepG2EWSR1
TIMP2ENSG00000035862.8858.70140617.904000.474703.887501.50150HepG2EXOSC5
TIMP2ENSG00000035862.81517.578501108.951900.452504.666103.23900HepG2FASTKD2
TIMP2ENSG00000035862.88034.993101755.080702.1947076.6681073.67910HepG2FIP1L1
TIMP2ENSG00000035862.82367.988201645.798000.524804.541802.42790HepG2FMR1
TIMP2ENSG00000035862.81018.37390509.447700.999206.855405.65200HepG2FUBP3
TIMP2ENSG00000035862.81973.80730795.120601.3116025.7079023.85210HepG2FXR1
TIMP2ENSG00000035862.83361.55320737.455002.1884065.6493062.58850HepG2G3BP1
TIMP2ENSG00000035862.81195.55280783.080600.610305.852204.54670HepG2G3BP2
TIMP2ENSG00000035862.81420.44500841.091000.755909.200107.61520HepG2GEMIN5
TIMP2ENSG00000035862.82595.906701186.541001.1294021.1194018.37760HepG2GNB2L1
TIMP2ENSG00000035862.82563.084401329.492000.946909.184206.59550HepG2GTF2F1
TIMP2ENSG00000035862.81817.295601091.339900.7356019.1576016.99460HepG2HDGF
TIMP2ENSG00000035862.82715.550801353.055101.004908.663506.14030HepG2HLTF
TIMP2ENSG00000035862.81104.989801369.73090-0.309902.382301.77920HepG2HNRNPA1
TIMP2ENSG00000035862.81113.715901523.54930-0.452104.421703.55910HepG2HNRNPC
TIMP2ENSG00000035862.81358.442102580.17640-0.9255025.0866023.23390HepG2HNRNPF
TIMP2ENSG00000035862.81553.33440747.057301.0560018.0476016.41660HepG2HNRNPK
TIMP2ENSG00000035862.82157.834801602.583700.429109.500808.32430HepG2HNRNPL
TIMP2ENSG00000035862.81944.431401513.478200.361405.840604.98730HepG2HNRNPU
TIMP2ENSG00000035862.81165.710702540.76140-1.1241031.7986029.69570HepG2IGF2BP1
TIMP2ENSG00000035862.82586.31050749.558601.7867048.2749045.87690HepG2IGF2BP2
TIMP2ENSG00000035862.82767.10840703.623101.975407.963306.36440HepG2IGF2BP3
TIMP2ENSG00000035862.81922.290101545.971800.314205.583004.57290HepG2ILF2
TIMP2ENSG00000035862.82441.54830754.018201.6950031.4365028.10910HepG2KHSRP
TIMP2ENSG00000035862.81300.748101044.950700.315804.276503.02030HepG2KIF1C
TIMP2ENSG00000035862.82709.974702016.332100.426402.875301.60260HepG2KRR1
TIMP2ENSG00000035862.85059.696502556.962800.9845013.3956011.60340HepG2LARP4
TIMP2ENSG00000035862.82226.223801162.496100.9373017.9029015.30860HepG2LARP7
TIMP2ENSG00000035862.82803.45400799.809001.8094025.9999024.24410HepG2MATR3
TIMP2ENSG00000035862.82967.82530988.633501.585804.067402.80330HepG2METAP2
TIMP2ENSG00000035862.83503.852201420.487801.3025041.0592038.57930HepG2MSI2
TIMP2ENSG00000035862.81658.587801192.779300.475505.314203.64660HepG2NAA15
TIMP2ENSG00000035862.82880.28390818.614901.8149046.5257044.17990HepG2NCBP2
TIMP2ENSG00000035862.82890.052901912.279500.595704.701102.84220HepG2NKRF
TIMP2ENSG00000035862.82786.396601744.469200.6755014.3598012.68600HepG2NOL12
TIMP2ENSG00000035862.82074.876601039.380000.997207.697505.85850HepG2NONO
TIMP2ENSG00000035862.82901.020201796.122500.691602.976201.31110HepG2NUP35
TIMP2ENSG00000035862.86094.325002577.769001.2412013.1740011.19610HepG2PABPC1
TIMP2ENSG00000035862.82261.76930728.873001.6336037.9131035.32630HepG2PABPC4
TIMP2ENSG00000035862.82749.224601498.113200.8758030.3650028.15490HepG2PARN
TIMP2ENSG00000035862.81707.62350713.093901.2597046.8944044.96700HepG2PCBP1
TIMP2ENSG00000035862.82132.823701334.717400.676105.163503.77470HepG2PCBP2
TIMP2ENSG00000035862.81526.147401087.065200.489404.512302.32470HepG2PES1
TIMP2ENSG00000035862.81082.48160781.242800.470405.095103.44450HepG2PKM
TIMP2ENSG00000035862.8543.839801349.90570-1.3116038.7006036.19320HepG2PPIL4
TIMP2ENSG00000035862.8870.665801139.25610-0.387904.653503.67810HepG2PRPF4
TIMP2ENSG00000035862.82072.42800873.365801.2466023.4220021.44050HepG2PRPF8
TIMP2ENSG00000035862.83064.36910725.633502.0782053.7937052.05560HepG2PTBP1
TIMP2ENSG00000035862.82389.226801665.216200.520706.756605.87970HepG2PUF60
TIMP2ENSG00000035862.82371.059501767.662600.423609.931708.95440HepG2PUM1
TIMP2ENSG00000035862.87255.492301766.395002.0382089.5624086.39620HepG2PUM2
TIMP2ENSG00000035862.81453.093201164.236400.319604.269303.53390HepG2PUS1
TIMP2ENSG00000035862.82273.72360785.806901.5327058.3583056.19920HepG2QKI
TIMP2ENSG00000035862.82382.085301287.658100.887406.681905.61280HepG2RAVER1
TIMP2ENSG00000035862.83297.598901666.005200.9849028.4344026.19570HepG2RBM15
TIMP2ENSG00000035862.82725.591501512.626700.8494025.2598024.01190HepG2RBM22
TIMP2ENSG00000035862.81961.52840713.197501.4595043.1931040.82660HepG2RBM25
TIMP2ENSG00000035862.82846.970701242.213001.196404.503702.35440HepG2RBM39
TIMP2ENSG00000035862.8765.242101138.31430-0.572904.866103.45330HepG2RCC2
TIMP2ENSG00000035862.82313.76870807.532301.5186024.9814023.68210HepG2NELFE
TIMP2ENSG00000035862.81519.51490752.157701.0144029.0076027.39240HepG2RECQL
TIMP2ENSG00000035862.81489.915902779.11950-0.8994017.1832015.76790HepG2RPLP0
TIMP2ENSG00000035862.82350.95260919.302601.3545039.4415037.60130HepG2RPS19
TIMP2ENSG00000035862.81736.037201292.809200.425203.643302.72920HepG2RPS2
TIMP2ENSG00000035862.81553.334502832.97090-0.866908.566907.18590HepG2RPS3A
TIMP2ENSG00000035862.82350.305101319.689300.8325012.7845010.49820HepG2RPS5
TIMP2ENSG00000035862.82668.97280863.950401.6272035.8640033.68740HepG2RRP9
TIMP2ENSG00000035862.8724.763801347.83290-0.8951024.7483023.08850HepG2SAFB2
TIMP2ENSG00000035862.81436.615302667.69450-0.892909.276607.01180HepG2SART3
TIMP2ENSG00000035862.81590.069002690.36810-0.758705.799403.62390HepG2SBDS
TIMP2ENSG00000035862.82267.41270922.526301.2973028.4037025.74850HepG2SERBP1
TIMP2ENSG00000035862.8520.451202752.92650-2.403105.177404.23500HepG2SF3B1
TIMP2ENSG00000035862.81554.32060755.417501.0408030.4145028.82230HepG2SF3B4
TIMP2ENSG00000035862.82371.566001571.823800.5933019.0728017.61600HepG2SMN1
TIMP2ENSG00000035862.81973.987901314.936600.586004.470503.23250HepG2SMNDC1
TIMP2ENSG00000035862.83732.031401708.482401.1271063.3302061.75230HepG2SRFBP1
TIMP2ENSG00000035862.81992.79990788.517101.3375056.3534054.82840HepG2SRSF1
TIMP2ENSG00000035862.84801.067301644.113001.54590106.29750103.19050HepG2SRSF5
TIMP2ENSG00000035862.81847.094502534.85430-0.456608.623107.51080HepG2SRSF7
TIMP2ENSG00000035862.83727.63740641.522002.53860243.59290240.39930HepG2SRSF9
TIMP2ENSG00000035862.81783.883501172.314200.605604.982303.37400HepG2STAU1
TIMP2ENSG00000035862.81913.647601203.449600.669004.814303.22240HepG2SUB1
TIMP2ENSG00000035862.83140.274501869.848300.7479028.6603027.01020HepG2SUCLG1
TIMP2ENSG00000035862.81669.031401185.149100.493805.845204.50120HepG2SUPT6H
TIMP2ENSG00000035862.85296.495901126.932102.2325072.5473070.14750HepG2SUPV3L1
TIMP2ENSG00000035862.81357.88230708.818700.9378021.3620020.01050HepG2TAF15
TIMP2ENSG00000035862.81346.65580755.362600.834009.296207.68740HepG2TFIP11
TIMP2ENSG00000035862.81785.34100651.234801.4548044.3526041.10190HepG2TIA1
TIMP2ENSG00000035862.8739.027601470.71350-0.9928021.6716020.51830HepG2TIAL1
TIMP2ENSG00000035862.82834.305201483.767600.9336037.0392035.27620HepG2TRIM56
TIMP2ENSG00000035862.81052.20690750.605000.487203.232801.53220HepG2TROVE2
TIMP2ENSG00000035862.82019.616301626.783800.312002.836601.95280HepG2TUFM
TIMP2ENSG00000035862.82713.225601420.904900.933102.907001.89230HepG2U2AF2
TIMP2ENSG00000035862.83904.368601721.884301.1810022.5349020.21330HepG2UBE2L3
TIMP2ENSG00000035862.82274.62220665.735301.7725047.0253044.20030HepG2UCHL5
TIMP2ENSG00000035862.83281.913801018.921801.68740117.91570114.85250HepG2UPF1
TIMP2ENSG00000035862.81376.023501047.319800.393705.011203.64280HepG2UTP18
TIMP2ENSG00000035862.8717.77730983.73120-0.454705.345704.55830HepG2UTP3
TIMP2ENSG00000035862.81945.403801416.448500.457702.788501.73040HepG2XRCC6
TIMP2ENSG00000035862.8742.642201109.34010-0.579004.749803.80810HepG2XRN2
TIMP2ENSG00000035862.82929.590701124.267801.3816084.9911082.39680HepG2ZC3H8
TIMP2ENSG00000035862.83479.392201120.621001.63440137.92550135.70710HepG2ZNF622
TIMP2ENSG00000035862.812.051300.0000099999.999903.060302.18590K562PCBP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TIMP2 is not available on ENCORE database.






No RBPs affect the alternative splcing events of TIMP2 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for TIMP2 is not avaliable on ENCORE database.