TBPL1

General Information

Gene Name       : TBPL1
Gene ID             : ENSG00000028839.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TBPL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TBPL1ENSG00000028839.924.5723.5824.07ENCSR000AEF
HepG2TBPL1ENSG00000028839.919.8230.5125.16ENCSR985KAT
K562TBPL1ENSG00000028839.986.1366.7576.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TBPL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TBPL1 RNA is bound by 25 proteins.  







eCLIP assay for TBPL1 is not avaliable on ENCORE database.





25 proteins are bound to TBPL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6134305806134305897+3'-UTR,CDS,intron-Distal,intron-Proximal3.506984.21588K562PRPF8
chr6134308292134308383+3'-UTR3.5178420.00678K562PUM2
chr6134301220134301241+3'-UTR4.561706.69007K562YBX3
chr6134303974134304062+3'-UTR,CDS,intron-Proximal3.389753.13218K562PRPF8
chr6134308504134308590+3'-UTR3.734174.25440K562TIA1
chr6134308489134308545+3'-UTR3.322775.16029K562DDX55
chr6134301241134301292+3'-UTR,CDS3.244087.79660K562YBX3
chr6134308211134308262+3'-UTR3.579874.51666K562RBM15
chr6134305530134305600+CDS,intron-Proximal4.769315.29045K562IGF2BP1
chr6134308029134308113+CDS,intron-Proximal4.1247115.02134K562SF3B4
chr6134305714134305761+CDS,intron-Distal,intron-Proximal3.569217.03308K562IGF2BP1
chr6134301386134301453+CDS,intron-Proximal3.369866.75365K562PRPF8
chr6134305728134305775+CDS,intron-Distal4.024298.57807K562YBX3
chr6134305382134305474+intron-Distal,intron-Proximal3.177555.57010K562KHSRP
chr6134274660134274799+intron-Distal,intron-Proximal4.285198.36737K562EFTUD2
chr6134278245134278303+intron-Distal4.583025.76606K562EXOSC5
chr6134274626134274762+intron-Distal,intron-Proximal3.599645.15405HepG2PRPF4
chr6134277456134277526+intron-Distal4.629444.10604K562METAP2
chr6134301468134301552+intron-Distal,intron-Proximal3.699119.14595K562PRPF8
chr6134275124134275155+intron-Distal3.017053.17504K562CSTF2T
chr6134287236134287297+intron-Distal3.407636.86548K562TARDBP
chr6134277452134277537+intron-Distal6.1038827.87055K562FMR1
chr6134274873134274942+intron-Distal3.808605.81451K562CSTF2T
chr6134277448134277556+intron-Distal4.8313530.74713K562CSTF2T
chr6134274713134274756+intron-Distal3.089124.10845K562DROSHA
chr6134301890134301998+intron-Distal3.041973.31457K562KHDRBS1
chr6134274584134274665+intron-Distal,intron-Proximal3.209293.19036K562XRN2
chr6134274687134274762+intron-Distal4.076213.18217HepG2NKRF
chr6134307006134307087+intron-Distal,intron-Proximal4.296324.12401HepG2U2AF2
chr6134274639134274763+intron-Distal,intron-Proximal4.180059.35150HepG2FAM120A
chr6134297727134297833+intron-Distal4.9746310.89911K562QKI
chr6134293356134293439+intron-Distal3.577586.09502K562QKI
chr6134274791134274843+intron-Distal4.320014.14056K562EWSR1
chr6134307904134307980+intron-Distal4.694066.93191K562KHSRP
chr6134274649134274774+intron-Distal,intron-Proximal4.5339715.00354K562GTF2F1
chr6134274803134274862+intron-Distal4.7243111.30843K562GTF2F1
chr6134274686134274765+intron-Distal3.664324.66361K562XRN2
chr6134274801134274867+intron-Distal3.043376.72143K562TIA1
chr6134301838134301884+intron-Distal3.173744.08064K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TBPL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TBPL1 is not available on ENCORE database.

  • 53 RBPs can affect the levels of TBPL1.  








The Knockdown/knockout RNA-Seq assay for TBPL1 is not available on ENCORE database.





53 RBPs can affect the gene expression of TBPL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TBPL1ENSG00000028839.5814.37430361.112101.1731012.7287011.67410HepG2AKAP1
TBPL1ENSG00000028839.5456.82040298.799400.612403.829202.90990HepG2ASCC1
TBPL1ENSG00000028839.5335.86670231.118900.539202.891702.28110HepG2BOP1
TBPL1ENSG00000028839.5378.34070239.618600.658802.943902.15330HepG2CNOT7
TBPL1ENSG00000028839.5147.46450233.02110-0.660103.435302.14130HepG2DDX1
TBPL1ENSG00000028839.5162.91630269.53990-0.726404.036402.82230HepG2DDX5
TBPL1ENSG00000028839.5165.36060232.81390-0.493602.271901.64810HepG2DKC1
TBPL1ENSG00000028839.5499.23920311.041800.682504.170103.24040HepG2FIP1L1
TBPL1ENSG00000028839.5158.90790230.67900-0.537702.121701.54820HepG2HNRNPA1
TBPL1ENSG00000028839.5178.37700299.11630-0.745804.115303.27760HepG2HNRNPK
TBPL1ENSG00000028839.5190.84570260.59960-0.449402.214201.56200HepG2IGF2BP1
TBPL1ENSG00000028839.5438.76130318.599100.461602.361401.75420HepG2MAGOH
TBPL1ENSG00000028839.5194.59540320.39340-0.719403.648302.93300HepG2MATR3
TBPL1ENSG00000028839.5230.32340327.94960-0.509802.253701.67930HepG2NCBP2
TBPL1ENSG00000028839.5120.65320203.52890-0.754403.020702.23960HepG2NSUN2
TBPL1ENSG00000028839.5132.03040229.74150-0.799102.780002.07410HepG2RAVER1
TBPL1ENSG00000028839.5793.57380400.186700.9876016.2698015.22440HepG2RBM22
TBPL1ENSG00000028839.587.85950193.08720-1.136006.195504.80380HepG2SERBP1
TBPL1ENSG00000028839.5359.39270244.360400.556502.806802.12840HepG2SF3A3
TBPL1ENSG00000028839.5383.90280252.804200.602602.533701.78660HepG2SNRNP70
TBPL1ENSG00000028839.5807.86100451.993900.8377014.6978013.78520HepG2SRFBP1
TBPL1ENSG00000028839.5219.44720392.43360-0.838608.481507.67970HepG2SSB
TBPL1ENSG00000028839.5116.21480223.71690-0.944905.086104.14740HepG2TARDBP
TBPL1ENSG00000028839.5174.16780247.67240-0.508002.537402.05460HepG2TIAL1
TBPL1ENSG00000028839.5489.20460266.125400.878207.395506.37460HepG2U2AF1
TBPL1ENSG00000028839.5154.46370216.70940-0.488502.245101.60520HepG2UPF1
TBPL1ENSG00000028839.5376.44180209.225900.847307.837106.91160HepG2UTP3
TBPL1ENSG00000028839.5368.51690252.650100.544502.425801.43410HepG2XRCC6
TBPL1ENSG00000028839.5169.15380238.34020-0.494702.645802.10800HepG2ZNF622
TBPL1ENSG00000028839.53238.163402739.525400.241103.462102.84010K562AGGF1
TBPL1ENSG00000028839.52129.433102729.98510-0.358403.167302.54730K562AQR
TBPL1ENSG00000028839.5875.894101200.38630-0.454704.629103.61640K562CPSF6
TBPL1ENSG00000028839.51438.939901152.533600.320103.815502.23300K562DDX27
TBPL1ENSG00000028839.52530.914602040.291100.310804.766703.94490K562DDX47
TBPL1ENSG00000028839.51979.479401426.934000.472105.138303.95920K562FIP1L1
TBPL1ENSG00000028839.5984.009901221.40360-0.311802.096101.34640K562FMR1
TBPL1ENSG00000028839.5812.898601035.26660-0.348902.142101.34230K562FTO
TBPL1ENSG00000028839.52056.976001390.422500.564902.599001.91750K562G3BP2
TBPL1ENSG00000028839.5732.279301058.75880-0.531904.332402.51870K562GEMIN5
TBPL1ENSG00000028839.5390.764501024.85500-1.3910028.0799024.61780K562HNRNPF
TBPL1ENSG00000028839.52890.300401934.509900.579207.773706.45710K562HSPD1
TBPL1ENSG00000028839.51256.812901656.03030-0.398002.598901.70700K562MATR3
TBPL1ENSG00000028839.51221.923301513.22730-0.308503.837702.89890K562MTPAP
TBPL1ENSG00000028839.51034.539701383.94170-0.419803.488202.09510K562NCBP2
TBPL1ENSG00000028839.51191.217501681.27680-0.4971011.5782010.19420K562NSUN2
TBPL1ENSG00000028839.51188.193301536.90140-0.371302.023801.31330K562PCBP3
TBPL1ENSG00000028839.5921.560601178.84700-0.355203.261502.38710K562POLR2G
TBPL1ENSG00000028839.52029.803001619.965100.325302.652101.85310K562PPIG
TBPL1ENSG00000028839.51475.342301027.660800.521605.128204.10690K562PRPF8
TBPL1ENSG00000028839.53664.009802827.010100.374003.483402.88510K562PUS1
TBPL1ENSG00000028839.5633.18270938.94270-0.568406.395804.88840K562RCC2
TBPL1ENSG00000028839.51432.003001050.788400.446502.764601.43900K562RRP9
TBPL1ENSG00000028839.51303.833601050.408700.311702.423901.41450K562SAFB
TBPL1ENSG00000028839.5543.84730879.42350-0.693404.678802.63320K562SERBP1
TBPL1ENSG00000028839.51309.269501659.07240-0.341604.267103.26960K562SF3A3
TBPL1ENSG00000028839.51087.345901323.10970-0.283102.664101.52220K562SRSF7
TBPL1ENSG00000028839.51236.790401599.49260-0.371002.103001.48040K562TARDBP
TBPL1ENSG00000028839.51527.135501822.96960-0.255502.896701.59780K562TROVE2
TBPL1ENSG00000028839.51772.282901391.456700.348903.652902.72780K562U2AF2
TBPL1ENSG00000028839.52908.839903796.32070-0.384205.062803.17950K562UBE2L3
TBPL1ENSG00000028839.51413.825101782.69780-0.334504.911303.98460K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TBPL1 is not available on ENCORE database.





3 RBPs can affect the splicing of TBPL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETBPL1ENSG00000028839.5chr6+134303688134303788134301219134301398134303954134304010-0.093000.000020.00084excludedK562SF3B4
SETBPL1ENSG00000028839.5chr6+134303680134303788134301169134301398134303954134304018-0.051000.000010.00014excludedK562AQR
SETBPL1ENSG00000028839.5chr6+134305714134305809134305513134305617134308098134311570-0.078000.000000.00000excludedK562AQR
SETBPL1ENSG00000028839.5chr6+1342899921342900951342743611342745631343012191343013980.103000.000000.00139includedK562KHSRP
A3SSTBPL1ENSG00000028839.5chr6+1343036881343037881343037051343037881343011691343013980.131000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TBPL1 is not avaliable on ENCORE database.