TMEM45B

General Information

Gene Name       : TMEM45B
Gene ID             : ENSG00000151715.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM45B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM45BENSG00000151715.70.000.000.00ENCSR000AEF
HepG2TMEM45BENSG00000151715.731.5930.4331.01ENCSR985KAT
K562TMEM45BENSG00000151715.70.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM45B is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM45B RNA is bound by 25 proteins.  







eCLIP assay for TMEM45B is not avaliable on ENCORE database.





25 proteins are bound to TMEM45B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11129729202129729246+3'-UTR3.814795.64093HepG2UPF1
chr11129728980129729017+3'-UTR3.223773.28764HepG2LARP4
chr11129729433129729476+3'-UTR4.121073.98590HepG2AKAP1
chr11129728556129728626+3'-UTR,CDS3.644207.54378HepG2LIN28B
chr11129728884129729014+3'-UTR4.311579.25614HepG2UPF1
chr11129728899129728954+3'-UTR3.456004.01829HepG2AKAP1
chr11129729621129729703+3'-UTR4.4392310.45182HepG2UPF1
chr11129729424129729487+3'-UTR4.067987.87703HepG2UPF1
chr11129728828129728884+3'-UTR3.936467.60345HepG2UPF1
chr11129728785129728828+3'-UTR3.133755.32195HepG2UPF1
chr11129729114129729178+3'-UTR4.868346.23064HepG2UPF1
chr11129722369129722386+3'-UTR,5'-UTR,CDS,intron-Proximal4.8077611.01919HepG2DDX3X
chr11129728764129728843+3'-UTR3.989038.82295HepG2LARP4
chr11129729268129729334+3'-UTR3.787534.54434HepG2UPF1
chr11129729644129729722+3'-UTR4.449095.18972HepG2AKAP1
chr11129728896129728963+3'-UTR4.253859.17978HepG2LIN28B
chr11129685746129685798+5'-UTR,intron-Proximal5.0808127.55914HepG2DDX3X
chr11129685744129685860+5'-UTR,intron-Proximal3.552763.90007HepG2NCBP2
chr11129725671129725731+CDS4.728459.16000HepG2SND1
chr11129725602129725671+CDS,intron-Proximal3.9842420.22019HepG2SND1
chr11129724628129724708+CDS4.9940317.93419HepG2SND1
chr11129725760129725788+CDS,intron-Proximal3.632484.22326HepG2SND1
chr11129727344129727390+CDS,intron-Proximal5.3403817.79328HepG2PRPF8
chr11129727289129727341+CDS3.466785.01195HepG2SND1
chr11129727207129727230+CDS,intron-Proximal3.902413.77917HepG2SND1
chr11129725611129725658+CDS4.480576.05571HepG2RPS3
chr11129722543129722592+CDS,intron-Proximal4.5903210.42975HepG2PRPF8
chr11129725728129725788+CDS,intron-Proximal5.291326.24443HepG2RPS3
chr11129722386129722478+CDS4.2936010.43313HepG2DDX3X
chr11129706352129706403+intron-Distal3.061655.81619HepG2HLTF
chr11129705350129705522+intron-Distal3.043176.27217HepG2BCLAF1
chr11129685941129686095+intron-Distal3.4201510.38206HepG2CSTF2T
chr11129703347129703410+intron-Distal3.056845.57689HepG2HLTF
chr11129704373129704405+intron-Distal3.014093.80877HepG2HLTF
chr11129693758129693838+intron-Distal3.348764.53157HepG2MATR3
chr11129718963129719010+intron-Distal3.846849.22024HepG2HNRNPL
chr11129691668129691698+intron-Distal3.500484.36087HepG2MATR3
chr11129691734129691836+intron-Distal3.1525412.39155HepG2MATR3
chr11129692504129692554+intron-Distal3.599156.79980HepG2SUGP2
chr11129710049129710110+intron-Distal3.682275.08047HepG2QKI
chr11129725241129725287+intron-Distal4.379703.04956HepG2HNRNPL
chr11129693909129694005+intron-Distal3.237008.22232HepG2HNRNPL
chr11129685972129686096+intron-Distal3.500515.12035HepG2DROSHA
chr11129685926129686076+intron-Distal4.8763031.48789HepG2PRPF4
chr11129702834129702878+intron-Distal3.086284.29582HepG2HLTF
chr11129720535129720626+intron-Distal,intron-Proximal4.326014.07628HepG2PTBP1
chr11129689435129689511+intron-Distal4.6532556.71813HepG2PTBP1
chr11129703737129703804+intron-Distal4.372309.43022HepG2HLTF
chr11129725116129725229+intron-Distal3.867438.97268HepG2HNRNPL
chr11129725392129725489+intron-Distal5.443267.07589HepG2HNRNPL
chr11129690810129690873+intron-Distal3.020244.97747HepG2MATR3
chr11129701590129701645+intron-Distal4.965325.05488HepG2QKI
chr11129695269129695346+intron-Distal3.395893.26775HepG2TAF15
chr11129705400129705449+intron-Distal4.325316.52185HepG2HLTF
chr11129719852129719931+intron-Distal4.626283.80778HepG2QKI
chr11129720711129720817+intron-Distal4.212873.50031HepG2HNRNPL
chr11129703682129703870+intron-Distal3.088725.66280HepG2GRWD1
chr11129692263129692380+intron-Distal4.5981916.22742HepG2MATR3
chr11129685868129685928+intron-Distal,intron-Proximal4.126074.45612HepG2FUS
chr11129708870129709011+intron-Distal3.8187212.14366HepG2PTBP1
chr11129705601129705651+intron-Distal3.009925.06972HepG2HLTF
chr11129685935129686036+intron-Distal4.563747.45939HepG2GTF2F1
chr11129725453129725578+intron-Distal,intron-Proximal5.7201912.16319HepG2QKI
chr11129725339129725392+intron-Distal4.741736.11322HepG2HNRNPL
chr11129705454129705551+intron-Distal4.2235112.37621HepG2HLTF
chr11129724942129725091+intron-Distal3.9776410.54997HepG2HNRNPL
chr11129713313129713371+intron-Distal3.534533.78824HepG2KHSRP
chr11129727359129727428+intron-Proximal4.248775.58296HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM45B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM45B is not available on ENCORE database.

  • 124 RBPs can affect the levels of TMEM45B.  








The Knockdown/knockout RNA-Seq assay for TMEM45B is not available on ENCORE database.





124 RBPs can affect the gene expression of TMEM45B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM45BENSG00000151715.3985.171001956.01410-0.989505.202103.95210HepG2ABCF1
TMEM45BENSG00000151715.32175.665305459.35280-1.3273026.4450024.99400HepG2AKAP1
TMEM45BENSG00000151715.33036.740202222.678600.450108.192306.95800HepG2AKAP8L
TMEM45BENSG00000151715.32708.326004517.02360-0.7380010.705309.23390HepG2ASCC1
TMEM45BENSG00000151715.33461.990402550.763400.440609.991508.82230HepG2AUH
TMEM45BENSG00000151715.33407.977601045.143401.7051019.1336017.11660HepG2BCLAF1
TMEM45BENSG00000151715.32183.941101464.757300.576203.849502.40750HepG2BUD13
TMEM45BENSG00000151715.31995.960401265.975600.6567011.382909.99020HepG2CALR
TMEM45BENSG00000151715.35718.208504291.526200.414004.117403.18520HepG2CIRBP
TMEM45BENSG00000151715.31958.132104062.53420-1.052909.847908.43750HepG2CNOT7
TMEM45BENSG00000151715.32158.17890539.111902.0011031.0049029.04190HepG2CPSF6
TMEM45BENSG00000151715.32975.425201609.896500.8860014.9238012.60750HepG2CPSF7
TMEM45BENSG00000151715.34704.452702655.435300.8250016.1495014.84850HepG2CELF1
TMEM45BENSG00000151715.31188.803702046.09480-0.7834024.1316022.25890HepG2DDX19B
TMEM45BENSG00000151715.32231.758901567.330600.509809.066907.16060HepG2DDX1
TMEM45BENSG00000151715.31232.256101892.19100-0.618809.462307.80640HepG2DDX24
TMEM45BENSG00000151715.31507.539401106.512800.446102.860801.55190HepG2DDX27
TMEM45BENSG00000151715.37035.609405229.362500.427904.045703.30060HepG2DDX3X
TMEM45BENSG00000151715.32073.206901182.494100.809909.781208.43110HepG2DDX55
TMEM45BENSG00000151715.31738.44690612.208501.5056015.7496013.57450HepG2DDX59
TMEM45BENSG00000151715.33505.328701667.176501.072006.644405.13520HepG2DDX5
TMEM45BENSG00000151715.36309.026404492.800500.489704.374703.61220HepG2DDX6
TMEM45BENSG00000151715.33222.875901482.293001.1204028.2034025.73760HepG2DHX30
TMEM45BENSG00000151715.31433.399902116.64140-0.5623012.1259010.91860HepG2DKC1
TMEM45BENSG00000151715.32931.698201536.887300.9316030.5012028.45650HepG2DNAJC21
TMEM45BENSG00000151715.3974.307401760.52980-0.8536012.1152010.38720HepG2EEF2
TMEM45BENSG00000151715.36126.927104318.373200.504605.416604.60470HepG2EIF2S1
TMEM45BENSG00000151715.31000.557101429.08450-0.514304.260603.15530HepG2EIF3D
TMEM45BENSG00000151715.32567.009504646.81430-0.856209.341408.11680HepG2EIF4B
TMEM45BENSG00000151715.31784.737002816.88830-0.6584018.5221016.75990HepG2EIF4G1
TMEM45BENSG00000151715.31124.717801693.81260-0.590702.499201.46050HepG2ESF1
TMEM45BENSG00000151715.32083.966502928.46410-0.490807.088906.20130HepG2ETF1
TMEM45BENSG00000151715.31547.282302161.78490-0.482502.481601.68960HepG2EWSR1
TMEM45BENSG00000151715.32633.773201842.354400.515507.045005.37440HepG2FASTKD2
TMEM45BENSG00000151715.31172.744401974.91320-0.751903.837402.94250HepG2FIP1L1
TMEM45BENSG00000151715.31463.48260984.293300.572105.615503.86450HepG2FKBP4
TMEM45BENSG00000151715.33452.823102860.240200.271502.318101.59450HepG2FUBP3
TMEM45BENSG00000151715.31433.060404815.70960-1.7486052.1594049.60990HepG2FXR1
TMEM45BENSG00000151715.32371.565204466.76480-0.9134014.3090012.85340HepG2G3BP1
TMEM45BENSG00000151715.33433.524804742.71240-0.466004.963503.76150HepG2G3BP2
TMEM45BENSG00000151715.3814.442201272.39340-0.643707.537806.08450HepG2GEMIN5
TMEM45BENSG00000151715.31740.362103761.18290-1.111808.563506.62850HepG2GRSF1
TMEM45BENSG00000151715.32663.247802112.127600.334405.497704.17050HepG2HDGF
TMEM45BENSG00000151715.33656.355902273.941100.685104.426102.63640HepG2HLTF
TMEM45BENSG00000151715.31110.597401551.60950-0.482405.054204.21580HepG2HNRNPA1
TMEM45BENSG00000151715.34385.497802624.100600.7408011.9961010.30630HepG2HNRNPA2B1
TMEM45BENSG00000151715.32159.286701536.219500.491103.897603.06050HepG2HNRNPF
TMEM45BENSG00000151715.32982.842504524.19930-0.601008.684507.49940HepG2HNRNPK
TMEM45BENSG00000151715.32035.77590583.155401.8035047.8009045.69070HepG2HNRNPLL
TMEM45BENSG00000151715.3555.165401362.07390-1.2948010.647409.00400HepG2HNRNPM
TMEM45BENSG00000151715.31179.297801714.42430-0.539807.901806.91700HepG2HNRNPU
TMEM45BENSG00000151715.32141.306403647.50360-0.768408.480706.39860HepG2HSPD1
TMEM45BENSG00000151715.31567.655604261.50280-1.442809.472007.73410HepG2IGF2BP3
TMEM45BENSG00000151715.32147.617501751.235800.294302.076701.43100HepG2ILF2
TMEM45BENSG00000151715.33221.512502022.326900.6716026.5850023.91430HepG2KIF1C
TMEM45BENSG00000151715.31920.672603644.59700-0.9241010.241507.95260HepG2KRR1
TMEM45BENSG00000151715.31685.687202311.03130-0.455203.082402.20250HepG2LARP4
TMEM45BENSG00000151715.31253.650901855.78190-0.565906.472604.65980HepG2LIN28B
TMEM45BENSG00000151715.31395.479104817.39520-1.7875052.2550049.65450HepG2MAGOH
TMEM45BENSG00000151715.32051.297704844.19920-1.2397024.0953022.38870HepG2MATR3
TMEM45BENSG00000151715.32533.743301597.521700.665305.927004.78480HepG2MSI2
TMEM45BENSG00000151715.31113.21880594.876200.904007.427805.80750HepG2MTPAP
TMEM45BENSG00000151715.32547.852801341.646600.9252010.611208.28010HepG2NAA15
TMEM45BENSG00000151715.33451.854304958.17860-0.522405.491504.61430HepG2NCBP2
TMEM45BENSG00000151715.31022.34920517.123100.9832013.5273012.00230HepG2NSUN2
TMEM45BENSG00000151715.36331.959003713.926100.769604.534303.37800HepG2PABPC1
TMEM45BENSG00000151715.31311.347801697.04640-0.372002.432401.63370HepG2PARN
TMEM45BENSG00000151715.32686.639304385.80780-0.7070024.9299023.41570HepG2PCBP1
TMEM45BENSG00000151715.33273.562302103.894300.637705.804403.33530HepG2PES1
TMEM45BENSG00000151715.32388.870801695.907700.494204.015701.99200HepG2PHF6
TMEM45BENSG00000151715.32171.132601529.137800.505604.450003.53540HepG2PPIL4
TMEM45BENSG00000151715.3762.921901214.48350-0.670703.728302.84220HepG2PRPF4
TMEM45BENSG00000151715.31351.948002362.93300-0.805505.344603.69630HepG2PRPF6
TMEM45BENSG00000151715.32788.647004462.91410-0.6784022.4393021.16700HepG2PTBP1
TMEM45BENSG00000151715.32279.587502702.74960-0.245702.039301.51560HepG2PUF60
TMEM45BENSG00000151715.31487.504102869.05160-0.9477048.6035046.75040HepG2PUM1
TMEM45BENSG00000151715.31917.876402866.97850-0.5800010.688709.41820HepG2PUM2
TMEM45BENSG00000151715.32690.383302253.465800.255603.867803.16300HepG2PUS1
TMEM45BENSG00000151715.32217.392104833.03990-1.1241032.0729030.31690HepG2QKI
TMEM45BENSG00000151715.34060.518702450.771700.7283017.5610015.71360HepG2RBM15
TMEM45BENSG00000151715.31236.754202447.68620-0.9849019.3748018.25850HepG2RBM22
TMEM45BENSG00000151715.33726.469404386.44790-0.235202.042101.45690HepG2RBM25
TMEM45BENSG00000151715.31003.098702130.98120-1.0871019.5828016.96940HepG2RBM27
TMEM45BENSG00000151715.31289.799101730.44850-0.424003.256502.10300HepG2RCC2
TMEM45BENSG00000151715.31294.445704966.63650-1.93990141.40060139.10060HepG2NELFE
TMEM45BENSG00000151715.31451.331904626.03420-1.67240104.47800101.88280HepG2RECQL
TMEM45BENSG00000151715.3532.138101390.63930-1.3859034.2461032.49470HepG2RPS19
TMEM45BENSG00000151715.31078.757201965.37220-0.8654013.3019011.64600HepG2RPS2
TMEM45BENSG00000151715.31650.249204081.75880-1.3065013.0095011.33090HepG2RPS3A
TMEM45BENSG00000151715.31443.64340902.564400.677503.039902.22150HepG2RRP9
TMEM45BENSG00000151715.32833.474101526.798800.8920038.2087036.23810HepG2SAFB2
TMEM45BENSG00000151715.3707.042201484.68980-1.070303.528201.95360HepG2SF1
TMEM45BENSG00000151715.32634.721401801.586800.548304.312903.46110HepG2SF3A3
TMEM45BENSG00000151715.3838.30840577.173400.538404.395903.52420HepG2SF3B1
TMEM45BENSG00000151715.33311.431904646.12780-0.488605.396604.61780HepG2SF3B4
TMEM45BENSG00000151715.3694.983801439.11070-1.050103.167101.59710HepG2SFPQ
TMEM45BENSG00000151715.33974.468602591.440800.6169024.1495022.47880HepG2SLBP
TMEM45BENSG00000151715.31481.36140642.219301.2057012.6495010.99100HepG2SNRNP70
TMEM45BENSG00000151715.35247.304002764.628100.9244037.6366036.34230HepG2SRFBP1
TMEM45BENSG00000151715.3753.772704849.69110-2.68570214.89900212.49920HepG2SRSF1
TMEM45BENSG00000151715.36952.412003945.602100.8172041.8578040.21310HepG2SRSF9
TMEM45BENSG00000151715.32539.861001318.338200.9459011.009208.76810HepG2STAU1
TMEM45BENSG00000151715.33701.383202027.242300.868408.496706.46860HepG2SUB1
TMEM45BENSG00000151715.31294.155203034.88870-1.2296070.5797068.26610HepG2SUCLG1
TMEM45BENSG00000151715.32314.837301332.832200.796309.084107.46340HepG2SUPT6H
TMEM45BENSG00000151715.32000.964404359.47850-1.1235046.5645044.63060HepG2TAF15
TMEM45BENSG00000151715.3562.512303569.46290-2.6658036.0359033.00000HepG2TBRG4
TMEM45BENSG00000151715.31235.97030789.077600.647306.826305.38160HepG2TFIP11
TMEM45BENSG00000151715.3642.259701666.06300-1.3752041.2394039.72960HepG2TIAL1
TMEM45BENSG00000151715.33501.593401680.763701.0588035.6736033.93650HepG2TRIM56
TMEM45BENSG00000151715.3791.319501688.92920-1.093806.961105.97490HepG2U2AF1
TMEM45BENSG00000151715.34186.298502794.795900.582806.308805.01160HepG2UBE2L3
TMEM45BENSG00000151715.3352.82250695.45320-0.9790010.641909.15940HepG2UCHL5
TMEM45BENSG00000151715.34816.847501597.738401.5920078.0920075.54540HepG2UPF1
TMEM45BENSG00000151715.31275.712101642.20390-0.364303.790902.58280HepG2UTP18
TMEM45BENSG00000151715.3811.260801542.54390-0.9271013.3273012.15970HepG2UTP3
TMEM45BENSG00000151715.35097.467803656.172600.479303.340302.12680HepG2XPO5
TMEM45BENSG00000151715.31361.439702385.38860-0.809105.741604.25080HepG2XRCC6
TMEM45BENSG00000151715.31515.111101158.833400.386702.638701.93080HepG2XRN2
TMEM45BENSG00000151715.33453.258101757.197400.9746018.8535017.73950HepG2ZNF622
TMEM45BENSG00000151715.31406.527802166.73650-0.623404.049902.45150HepG2ZRANB2
TMEM45BENSG00000151715.30.000007.34050-99999.999992.036401.33760K562MTPAP
TMEM45BENSG00000151715.30.000008.05040-99999.999992.362201.60270K562SF3A3
TMEM45BENSG00000151715.30.000008.24850-99999.999992.406901.52590K562SRPK2
TMEM45BENSG00000151715.30.000008.64290-99999.999992.515901.82900K562UPF1
TMEM45BENSG00000151715.30.000007.39480-99999.999992.162701.39040K562WDR3
TMEM45BENSG00000151715.30.000007.69430-99999.999992.281601.50640K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM45B is not available on ENCORE database.





10 RBPs can affect the splicing of TMEM45B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM45BENSG00000151715.3chr11+1297279331297280331297272071297273531297284681297298980.059000.000000.00000includedHepG2U2AF1
SETMEM45BENSG00000151715.3chr11+1297279331297280331297272071297273531297284681297298980.101000.000000.00000includedHepG2U2AF2
SETMEM45BENSG00000151715.3chr11+129698041129698148129685757129685793129722369129722555-0.118000.000340.00559excludedHepG2U2AF2
SETMEM45BENSG00000151715.3chr11+1296980411296981481296857571296857931297223691297225550.065000.000000.00010includedHepG2NCBP2
SETMEM45BENSG00000151715.3chr11+129709443129709597129698041129698148129722369129722555-0.432000.000580.03819excludedHepG2NCBP2
SETMEM45BENSG00000151715.3chr11+129709447129709597129685713129685793129722369129722555-0.118000.001090.06319excludedHepG2FTO
SETMEM45BENSG00000151715.3chr11+1297204441297204991296857131296857931297223691297225550.053000.000000.00018includedHepG2MATR3
SETMEM45BENSG00000151715.3chr11+129698041129698148129685757129685793129722369129722555-0.061000.000850.05798excludedHepG2HNRNPL
SETMEM45BENSG00000151715.3chr11+129698041129698148129685757129685793129722369129722555-0.128000.000120.02521excludedHepG2HNRNPUL1
SETMEM45BENSG00000151715.3chr11+1296980411296981481296857571296857931297223691297225550.055000.000340.03034includedHepG2IGF2BP3
SETMEM45BENSG00000151715.3chr11+129709447129709597129685713129685793129722369129722555-0.075000.000550.02711excludedHepG2HNRNPU
SETMEM45BENSG00000151715.3chr11+1296980411296981481296857571296857931297223691297225550.052000.000020.00732includedHepG2KHSRP
MXETMEM45BENSG00000151715.3chr11+129709447129709597129720444129720499129685713129685793129722369129722555-0.329000.002530.060222includedHepG2MATR3
MXETMEM45BENSG00000151715.3chr11+1296980411296981481297094471297095971296969181296970091297223691297225550.394000.000050.011341includedHepG2KHSRP
MXETMEM45BENSG00000151715.3chr11+1296980411296981481297094471297095971296969181296970091297223691297225550.464000.000030.002411includedHepG2NCBP2
MXETMEM45BENSG00000151715.3chr11+129709447129709597129721568129721687129685713129685793129722369129722555-0.313000.000390.017592includedHepG2NCBP2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM45B is not avaliable on ENCORE database.