METTL16

General Information

Gene Name       : METTL16
Gene ID             : ENSG00000127804.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: METTL16)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878METTL16ENSG00000127804.1215.4916.7616.12ENCSR000AEF
HepG2METTL16ENSG00000127804.1211.9915.5813.79ENCSR985KAT
K562METTL16ENSG00000127804.1213.2813.9813.63ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for METTL16 is not avaliable on ENCORE database.



Proteins bound to RNA
  • METTL16 RNA is bound by 13 proteins.  







eCLIP assay for METTL16 is not avaliable on ENCORE database.





13 proteins are bound to METTL16 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1723234352323506-3'-UTR,CDS,intron-Distal,intron-Proximal3.089503.07152HepG2HLTF
chr1723214402321489-3'-UTR,intron-Distal4.0869914.88180K562TARDBP
chr1723203822320440-3'-UTR,intron-Distal4.948335.15256K562AKAP1
chr1723223672322446-3'-UTR,intron-Distal4.141149.71169K562UPF1
chr1723215652321675-3'-UTR,intron-Distal4.8923410.36387K562AKAP1
chr1723214412321492-3'-UTR,intron-Distal3.207537.31176K562UPF1
chr1723237072323787-3'-UTR,CDS,intron-Distal3.930533.79347HepG2GRWD1
chr1723220102322070-3'-UTR,intron-Distal3.982413.60235HepG2HNRNPM
chr1723222112322290-3'-UTR,intron-Distal3.145344.09267K562FAM120A
chr1723240532324139-3'-UTR,CDS,intron-Distal3.819343.31827HepG2GRWD1
chr1723226772322716-3'-UTR,intron-Distal4.248573.26739K562FAM120A
chr1723208342320920-3'-UTR,intron-Distal5.414719.47550K562UPF1
chr1723675722367642-3'-UTR,CDS,intron-Distal,intron-Proximal3.955853.79347HepG2GRWD1
chr1723222602322334-3'-UTR,intron-Distal4.8345112.17194K562UPF1
chr1723237032323804-3'-UTR,CDS,intron-Distal3.028924.30396K562UCHL5
chr1723230242323076-3'-UTR,intron-Distal,intron-Proximal5.014677.35154K562UPF1
chr1723201382320221-3'-UTR,intron-Distal4.384057.49447K562UPF1
chr1723208772320909-3'-UTR,intron-Distal3.956093.11728K562FAM120A
chr1723811222381190-5'-UTR,CDS,intron-Distal,intron-Proximal3.497273.02321K562U2AF2
chr1723768392376951-5'-UTR,CDS,intron-Distal3.210353.60157HepG2GRWD1
chr1723768502376931-5'-UTR,CDS,intron-Distal3.996785.35703HepG2BCLAF1
chr1723811262381171-5'-UTR,CDS,intron-Distal4.165303.45943HepG2BCLAF1
chr1723769162376968-CDS,intron-Distal,intron-Proximal3.705413.19080K562U2AF2
chr1723457342345780-intron-Distal4.330323.18981K562PTBP1
chr1723312692331362-intron-Distal4.7598310.19703HepG2PCBP2
chr1723812312381323-intron-Distal,intron-Proximal3.762203.08314K562TARDBP
chr1723185662318617-CDS,intron-Distal,intron-Proximal3.248423.60305HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for METTL16 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for METTL16 is not available on ENCORE database.

  • 65 RBPs can affect the levels of METTL16.  








The Knockdown/knockout RNA-Seq assay for METTL16 is not available on ENCORE database.





65 RBPs can affect the gene expression of METTL16 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
METTL16ENSG00000127804.81105.30510873.120000.340101.805301.36550HepG2AKAP1
METTL16ENSG00000127804.8492.33370722.43080-0.553203.985103.05020HepG2ASCC1
METTL16ENSG00000127804.8438.48710609.65060-0.475403.264502.62110HepG2BOP1
METTL16ENSG00000127804.8926.02770639.481500.534108.193207.16630HepG2CKAP4
METTL16ENSG00000127804.8318.09730559.68900-0.815207.206306.13940HepG2CPSF6
METTL16ENSG00000127804.8682.80270836.15220-0.292302.472601.85830HepG2CELF1
METTL16ENSG00000127804.8692.52910899.16680-0.376704.660603.73600HepG2DAZAP1
METTL16ENSG00000127804.8463.76480571.33620-0.300901.992201.38470HepG2DNAJC21
METTL16ENSG00000127804.8439.76360690.67780-0.651305.012104.22660HepG2EIF2S1
METTL16ENSG00000127804.8634.35320849.70330-0.421703.172602.30330HepG2EIF4G2
METTL16ENSG00000127804.8894.826701180.00190-0.399104.787504.03560HepG2ETF1
METTL16ENSG00000127804.8930.75020723.417300.363502.398301.74600HepG2HNRNPK
METTL16ENSG00000127804.8321.26440605.46000-0.914308.691907.64220HepG2HNRNPLL
METTL16ENSG00000127804.8473.88240637.33920-0.427504.077203.35260HepG2HNRNPU
METTL16ENSG00000127804.8582.70680782.56080-0.425403.701602.87420HepG2IGF2BP1
METTL16ENSG00000127804.8519.41450651.02320-0.325802.379301.69230HepG2ILF2
METTL16ENSG00000127804.8440.23780584.69670-0.409403.870602.66820HepG2KIF1C
METTL16ENSG00000127804.8801.41300615.969300.379603.606802.73480HepG2PRPF4
METTL16ENSG00000127804.8619.77000851.08940-0.457603.990603.28980HepG2PUF60
METTL16ENSG00000127804.8994.04080667.327400.574802.771602.06650HepG2RAVER1
METTL16ENSG00000127804.81293.84100986.262000.391504.445603.82930HepG2RBM22
METTL16ENSG00000127804.81939.33770777.186601.3191018.6399016.82230HepG2SF3A3
METTL16ENSG00000127804.8772.21500599.280200.365702.352901.69970HepG2SF3B1
METTL16ENSG00000127804.8977.72220803.243300.283502.525601.95620HepG2SF3B4
METTL16ENSG00000127804.8608.83330815.99670-0.422505.092804.18670HepG2SLBP
METTL16ENSG00000127804.81029.33200838.441900.295802.824302.34750HepG2SRSF1
METTL16ENSG00000127804.8577.06540840.28870-0.542207.117806.17770HepG2SRSF5
METTL16ENSG00000127804.8610.14090780.78760-0.355803.402902.64210HepG2SRSF7
METTL16ENSG00000127804.8368.07280634.46090-0.785505.730204.81120HepG2SUPV3L1
METTL16ENSG00000127804.8413.39930590.16160-0.513603.545402.73700HepG2TARDBP
METTL16ENSG00000127804.8431.63870624.82680-0.533606.005205.23100HepG2TRIM56
METTL16ENSG00000127804.8963.19650640.566400.588405.374604.51480HepG2U2AF1
METTL16ENSG00000127804.8651.64570880.01740-0.433402.546101.74350HepG2UBE2L3
METTL16ENSG00000127804.8470.41760689.24590-0.551106.624705.61960HepG2UPF1
METTL16ENSG00000127804.81013.43620665.439500.606809.175508.18940HepG2UTP3
METTL16ENSG00000127804.8482.42990607.89200-0.333502.761002.08940HepG2ZC3H8
METTL16ENSG00000127804.82800.288401241.185901.1738027.6818026.02660K562AQR
METTL16ENSG00000127804.8409.67610672.13590-0.714306.209504.89020K562BOP1
METTL16ENSG00000127804.8845.804001249.07720-0.562502.944801.84330K562CNOT7
METTL16ENSG00000127804.8537.23800714.64740-0.411703.187702.34460K562CPSF6
METTL16ENSG00000127804.8874.52730712.464300.295602.369001.56760K562DKC1
METTL16ENSG00000127804.8958.90010752.036000.350502.311501.47700K562EFTUD2
METTL16ENSG00000127804.8471.84510617.25290-0.387503.313401.97780K562EIF2S1
METTL16ENSG00000127804.8687.325201081.51360-0.6540010.446709.18650K562EIF2S2
METTL16ENSG00000127804.8677.19880493.525700.456403.912602.97480K562EIF3G
METTL16ENSG00000127804.8777.73260587.108500.405502.941502.09520K562EIF4A3
METTL16ENSG00000127804.8406.20380528.71680-0.380302.737801.59270K562EIF4B
METTL16ENSG00000127804.8689.698201083.04080-0.651107.290105.85100K562FIP1L1
METTL16ENSG00000127804.8523.04890727.18680-0.475403.475502.51380K562FMR1
METTL16ENSG00000127804.8923.87130610.567000.597407.981207.02150K562FXR1
METTL16ENSG00000127804.8528.94620682.29180-0.367302.313501.58690K562GPKOW
METTL16ENSG00000127804.8867.057301441.23030-0.7331010.330108.84560K562GRSF1
METTL16ENSG00000127804.8991.80140674.239800.556703.771502.30480K562HNRNPK
METTL16ENSG00000127804.81009.984501468.38680-0.539905.706704.57920K562HSPD1
METTL16ENSG00000127804.8960.00380709.482500.436203.947802.93720K562MAGOH
METTL16ENSG00000127804.81310.764901715.05090-0.387803.119001.91640K562MSI2
METTL16ENSG00000127804.8424.01100586.27210-0.467503.591902.17020K562NCBP2
METTL16ENSG00000127804.81139.98420631.262700.8526012.2064010.08040K562PCBP2
METTL16ENSG00000127804.8813.027401229.45180-0.596606.420305.08130K562PPIG
METTL16ENSG00000127804.81056.54680731.816700.529704.637403.66760K562PRPF8
METTL16ENSG00000127804.8453.02560601.93570-0.410002.310001.48960K562PSIP1
METTL16ENSG00000127804.8965.19740689.307100.485605.001104.13170K562PTBP1
METTL16ENSG00000127804.81416.964701829.59550-0.368704.340103.13210K562PUM2
METTL16ENSG00000127804.8895.71350639.753200.485404.422803.69100K562RBM15
METTL16ENSG00000127804.8945.85050660.960000.516904.800003.65780K562RBM22
METTL16ENSG00000127804.81114.23020599.269600.8947016.3831014.14740K562SF3B4
METTL16ENSG00000127804.8925.74600675.751400.454004.148403.29030K562SRSF1
METTL16ENSG00000127804.8489.06090638.19790-0.384002.460801.47770K562SRSF5
METTL16ENSG00000127804.8381.27560509.07640-0.417002.981701.64640K562SSB
METTL16ENSG00000127804.8501.98180708.60070-0.497303.139302.05590K562SUPV3L1
METTL16ENSG00000127804.8485.54200659.70210-0.442203.398502.47780K562TIA1
METTL16ENSG00000127804.8438.57620578.97940-0.400702.112801.30650K562TIAL1
METTL16ENSG00000127804.81011.597101208.76580-0.256902.696901.44470K562TROVE2
METTL16ENSG00000127804.8460.71520749.94460-0.702906.373804.75220K562UCHL5
METTL16ENSG00000127804.8833.446301149.43890-0.463802.774302.05430K562UPF1
METTL16ENSG00000127804.81026.038801398.30910-0.446604.470703.33290K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for METTL16 is not available on ENCORE database.





9 RBPs can affect the splicing of METTL16 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMETTL16ENSG00000127804.8chr17-237105423711702367501236764423768172376958-0.347000.000050.00175excludedK562SF3B4
SEMETTL16ENSG00000127804.8chr17-237105423711702367501236764423768172376958-0.344000.000570.00876excludedHepG2U2AF2
SEMETTL16ENSG00000127804.8chr17-237105423711702367501236764423768172376986-0.297000.000000.00000excludedK562AQR
SEMETTL16ENSG00000127804.8chr17-2378534237867623768172376958238097923811790.085000.000370.03992includedHepG2SRSF7
SEMETTL16ENSG00000127804.8chr17-237105423711702367501236764423768172376958-0.357000.000050.00191excludedK562U2AF1
SEMETTL16ENSG00000127804.8chr17-237105423711702367501236764423768172376958-0.207000.003350.07796excludedHepG2SF3A3
SEMETTL16ENSG00000127804.8chr17-237105423711702367501236764423768172376958-0.342000.000250.00631excludedK562U2AF2
A3SSMETTL16ENSG00000127804.8chr17-2341402234158423414022341492234478323448530.143000.000000.00000longerK562AQR
A3SSMETTL16ENSG00000127804.8chr17-2380979238120623809792381179240549724056250.085000.004000.02374longerK562AQR
A3SSMETTL16ENSG00000127804.8chr17-2376817237698623768172376958238097923812060.127000.000000.00004longerK562AQR
MXEMETTL16ENSG00000127804.8chr17-237105423711702376817237698623675012367644238097923811790.328000.000000.000001includedK562AQR
MXEMETTL16ENSG00000127804.8chr17-234140223414922367562236764423240242324198238097923811790.127000.003300.025361includedK562AQR
MXEMETTL16ENSG00000127804.8chr17-234140223414922367501236764423240242324198238097923811790.155000.000200.002211includedK562AQR
MXEMETTL16ENSG00000127804.8chr17-237105423711882376817237698623675622367644238097923811790.330000.000000.000001includedK562AQR
MXEMETTL16ENSG00000127804.8chr17-237105423711702376817237695823675012367644238097923811790.175000.003240.021371includedHepG2U2AF2
MXEMETTL16ENSG00000127804.8chr17-237105423711702376817237695823675012367644238097923811790.263000.000370.016621includedHepG2HNRNPC
MXEMETTL16ENSG00000127804.8chr17-237105423711702376817237695823675012367644238097923811790.188000.000300.013561includedK562PPIL4
MXEMETTL16ENSG00000127804.8chr17-23710542371170237681723769582367501236764423809792381179-0.343000.003970.069712includedK562FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for METTL16 is not avaliable on ENCORE database.