SPECC1L

General Information

Gene Name       : SPECC1L
Gene ID             : ENSG00000100014.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SPECC1L)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPECC1LENSG00000100014.1913.5714.3413.96ENCSR000AEF
HepG2SPECC1LENSG00000100014.1919.0322.4520.74ENCSR985KAT
K562SPECC1LENSG00000100014.198.479.759.11ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPECC1L is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPECC1L RNA is bound by 24 proteins.  







eCLIP assay for SPECC1L is not avaliable on ENCORE database.





24 proteins are bound to SPECC1L RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr222481268224812794+3'-UTR,intron-Distal4.181637.44279HepG2GRSF1
chr222469816224698225+3'-UTR,5'-UTR,CDS,intron-Proximal3.269905.74981HepG2GRWD1
chr222481126324811336+3'-UTR,intron-Distal5.7299911.61967K562UPF1
chr222481169924811759+3'-UTR,intron-Distal4.053827.95535HepG2AKAP1
chr222481112324811174+3'-UTR,intron-Distal4.921247.10674HepG2UPF1
chr222481152824811597+3'-UTR,intron-Distal4.7226917.08773K562UPF1
chr222469817224698201+3'-UTR,5'-UTR,CDS3.728303.68471HepG2BCLAF1
chr222481140524811443+3'-UTR,intron-Distal3.295033.68605HepG2AKAP1
chr222481074324810806+3'-UTR,intron-Proximal5.5142511.27805HepG2UPF1
chr222481247024812537+3'-UTR,intron-Distal5.9341813.64218K562UPF1
chr222481066924810737+3'-UTR,intron-Proximal5.198718.06720HepG2AKAP1
chr222481261324812698+3'-UTR,intron-Distal4.114977.84191HepG2UPF1
chr222481067124810743+3'-UTR,intron-Proximal5.9433615.41547HepG2UPF1
chr222481145824811528+3'-UTR,intron-Distal6.1416916.29100K562UPF1
chr222481286024812934+3'-UTR,intron-Distal4.245229.37691K562UPF1
chr222481313024813166+3'-UTR,intron-Distal5.030926.81621K562UPF1
chr222481264324812683+3'-UTR,intron-Distal3.922967.71860K562UPF1
chr222481238624812462+3'-UTR,intron-Distal5.7772833.83289K562UPF1
chr222481117724811320+3'-UTR,intron-Distal5.4972423.50738HepG2UPF1
chr222481096524811088+3'-UTR,intron-Distal4.4364614.61601HepG2UPF1
chr222470930724709338+3'-UTR,CDS4.567343.89826HepG2BCLAF1
chr222481094224811031+3'-UTR,intron-Distal4.4339110.03265HepG2AKAP1
chr222481073724810792+3'-UTR,intron-Proximal5.073068.89452HepG2AKAP1
chr222481088324810916+3'-UTR,intron-Distal3.229143.44343HepG2AKAP1
chr222481104324811106+3'-UTR,intron-Distal4.985177.27295HepG2AKAP1
chr222481239024812445+3'-UTR,intron-Distal4.107287.95535HepG2AKAP1
chr222481116724811247+3'-UTR,intron-Distal5.5044312.24108HepG2AKAP1
chr222481260024812643+3'-UTR,intron-Distal4.456377.83400K562UPF1
chr222481171124811762+3'-UTR,intron-Distal4.583666.20043HepG2UPF1
chr222481082324810849+3'-UTR,intron-Distal3.967363.08342HepG2AKAP1
chr222466680324666913+5'-UTR3.074577.09702HepG2DDX3X
chr222466687524666961+5'-UTR,intron-Proximal3.247057.46719HepG2NCBP2
chr222471868424718740+CDS,intron-Distal3.534783.80897HepG2FXR2
chr222473441124734441+CDS4.165284.23295HepG2GRWD1
chr222471788724717936+CDS,intron-Distal4.841835.85077HepG2FXR2
chr222471859024718758+CDS,intron-Distal3.558457.47194HepG2GRWD1
chr222471790424718038+CDS,intron-Distal3.836303.21664HepG2UCHL5
chr222471864424718772+CDS,intron-Distal4.1650715.85384HepG2BCLAF1
chr222471828224718327+CDS,intron-Distal3.310873.43213K562UCHL5
chr222473037724730395+CDS,intron-Proximal3.039113.45280HepG2BCLAF1
chr222471794024718054+CDS,intron-Distal4.196787.50845HepG2GRWD1
chr222473442324734488+CDS,intron-Proximal5.410297.02967HepG2PRPF8
chr222471797824718040+CDS,intron-Distal3.854756.13983HepG2HLTF
chr222472028324720347+CDS4.533787.97334HepG2BCLAF1
chr222473439824734432+CDS4.238603.71264HepG2FXR2
chr222471859324718696+CDS,intron-Distal3.359855.04943K562ZNF622
chr222471795124718030+CDS,intron-Distal4.713764.53233HepG2ZNF800
chr222472622224726275+CDS,intron-Proximal5.245648.25598HepG2PPIG
chr222471865124718724+CDS,intron-Distal3.813524.49347K562UCHL5
chr222475924724759287+3'-UTR,CDS3.169114.26492HepG2BCLAF1
chr222471860724718651+CDS,intron-Distal3.589064.40383K562UCHL5
chr222471787124717933+CDS,intron-Distal3.503064.41784HepG2GRWD1
chr222472634624726400+CDS,intron-Proximal4.223047.16838HepG2BCLAF1
chr222471759024717719+CDS,intron-Distal3.2558810.13621HepG2BCLAF1
chr222476146624761524+3'-UTR,CDS3.634585.74979HepG2GRWD1
chr222472484124724889+CDS,intron-Proximal3.070783.47879HepG2PPIG
chr222471829824718367+CDS,intron-Distal3.576307.89260HepG2BCLAF1
chr222476522424765284+3'-UTR,CDS3.469124.02291HepG2GRWD1
chr222480766224807720+3'-UTR,CDS,intron-Distal,intron-Proximal3.704033.86479HepG2PRPF8
chr222472622424726280+CDS4.428578.41475HepG2BCLAF1
chr222471735724717393+CDS,intron-Distal,intron-Proximal3.664079.25117K562YBX3
chr222475924224759303+3'-UTR,CDS3.092384.91547HepG2GRWD1
chr222472622324726285+CDS,intron-Proximal3.691625.52031HepG2GRWD1
chr222473037624730454+CDS,intron-Proximal4.936355.97118HepG2FXR2
chr222480766924807710+3'-UTR,CDS,intron-Distal,intron-Proximal4.171313.59236HepG2AQR
chr222471729724717400+CDS,intron-Distal,intron-Proximal3.394447.43909HepG2BCLAF1
chr222473037624730441+CDS,intron-Proximal3.305323.61259K562ZNF622
chr222473438124734433+CDS3.495385.15500HepG2BCLAF1
chr222471731924717465+CDS,intron-Distal,intron-Proximal3.687828.97406HepG2GRWD1
chr222467875924678815+intron-Distal4.146513.21162HepG2HNRNPC
chr222477160224771655+intron-Distal4.794616.20441HepG2HLTF
chr222474601924746057+intron-Distal4.088733.86809HepG2SUGP2
chr222476727724767352+intron-Distal3.883363.95960K562SAFB2
chr222480060924800751+intron-Distal4.886537.87489HepG2HNRNPK
chr222474589124745955+intron-Distal4.503775.35792HepG2SUGP2
chr222479809624798180+intron-Distal3.665855.34807K562ILF3
chr222474574824745851+intron-Distal5.3399811.58997HepG2SUGP2
chr222479809324798181+intron-Distal6.3578878.94663HepG2PCBP2
chr222479806924798185+intron-Distal5.9668636.59016HepG2HNRNPK
chr222480336324803442+intron-Distal3.211294.67779HepG2SUGP2
chr222477113224771181+intron-Distal3.936503.26547HepG2HLTF
chr222475511624755195+intron-Distal4.978054.40618K562PTBP1
chr222475511624755182+intron-Distal3.646306.10762HepG2PTBP1
chr222477105824771182+intron-Distal3.846473.12651K562SAFB2
chr222479809724798202+intron-Distal5.8513113.53164HepG2ILF3
chr222474460924744698+intron-Distal3.222475.12506HepG2SUGP2
chr222474608424746134+intron-Distal3.207253.59523HepG2SUGP2
chr222479808924798250+intron-Distal4.3235315.61714HepG2DDX59
chr222476529324765314+intron-Proximal4.377103.71570HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPECC1L is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPECC1L is not available on ENCORE database.

  • 65 RBPs can affect the levels of SPECC1L.  








The Knockdown/knockout RNA-Seq assay for SPECC1L is not available on ENCORE database.





65 RBPs can affect the gene expression of SPECC1L :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPECC1LENSG00000100014.151620.650302118.18760-0.386302.772101.82870HepG2ABCF1
SPECC1LENSG00000100014.151964.431001616.759400.280903.978103.27380HepG2ACO1
SPECC1LENSG00000100014.151316.278501624.34300-0.303403.709302.83420HepG2AKAP8L
SPECC1LENSG00000100014.152745.811202395.262900.196902.246301.61600HepG2AUH
SPECC1LENSG00000100014.151485.412101887.31590-0.345502.913902.21080HepG2CPSF6
SPECC1LENSG00000100014.151382.643901744.82900-0.335702.722701.62570HepG2CPSF7
SPECC1LENSG00000100014.15794.311501271.46740-0.678707.715406.64040HepG2DDX21
SPECC1LENSG00000100014.15938.249701434.28500-0.612305.108104.09740HepG2DDX55
SPECC1LENSG00000100014.151136.672001622.41910-0.513303.902303.17800HepG2DDX6
SPECC1LENSG00000100014.15963.601701162.56890-0.270802.389101.72970HepG2DNAJC21
SPECC1LENSG00000100014.15947.749801152.25080-0.281903.360202.65420HepG2DNAJC2
SPECC1LENSG00000100014.15848.188701170.32290-0.464402.987401.83060HepG2AGO1
SPECC1LENSG00000100014.15812.217401211.34450-0.576706.854705.19630HepG2FASTKD2
SPECC1LENSG00000100014.152680.731202138.954300.325602.280301.57830HepG2FIP1L1
SPECC1LENSG00000100014.151102.274601570.98750-0.511203.219602.01290HepG2FUS
SPECC1LENSG00000100014.152625.071102139.411700.295001.906401.36890HepG2GPKOW
SPECC1LENSG00000100014.151177.381501683.93480-0.516309.047907.54040HepG2HNRNPA2B1
SPECC1LENSG00000100014.151262.445801669.05200-0.402807.235506.19270HepG2HNRNPL
SPECC1LENSG00000100014.151609.108701296.883700.311104.086303.36070HepG2HNRNPU
SPECC1LENSG00000100014.151534.183702163.68740-0.496003.646402.23220HepG2HSPD1
SPECC1LENSG00000100014.151291.423601639.73340-0.344502.388501.75580HepG2IGF2BP2
SPECC1LENSG00000100014.152178.818401739.657900.324602.260201.66500HepG2MAGOH
SPECC1LENSG00000100014.152049.004901726.143100.247302.867402.08270HepG2PRPF4
SPECC1LENSG00000100014.15841.648401106.50180-0.394702.531501.75740HepG2PRPF8
SPECC1LENSG00000100014.152171.804301839.787900.239302.164001.56800HepG2PUM2
SPECC1LENSG00000100014.152045.867301755.958900.220401.956101.41660HepG2QKI
SPECC1LENSG00000100014.151956.070902372.67970-0.278602.701701.85200HepG2RBM15
SPECC1LENSG00000100014.152716.298702071.155900.391103.969303.17550HepG2RPLP0
SPECC1LENSG00000100014.151773.677402351.09560-0.406602.690802.02630HepG2SF3A3
SPECC1LENSG00000100014.151545.724001346.875300.198602.224601.63790HepG2SMN1
SPECC1LENSG00000100014.152077.785501761.969700.237802.946402.46240HepG2SRSF1
SPECC1LENSG00000100014.152525.904102254.083800.164201.791701.35730HepG2SSB
SPECC1LENSG00000100014.152463.355901947.536400.338906.398005.52140HepG2SUCLG1
SPECC1LENSG00000100014.151213.905701990.02740-0.7131010.102308.84410HepG2TARDBP
SPECC1LENSG00000100014.15593.28700957.03490-0.689806.325304.92230HepG2TFIP11
SPECC1LENSG00000100014.15959.353401271.42560-0.406305.683804.92820HepG2TRIM56
SPECC1LENSG00000100014.152259.285201793.555800.332902.221001.47550HepG2UBE2L3
SPECC1LENSG00000100014.151649.682202085.06080-0.337905.576004.63870HepG2UPF1
SPECC1LENSG00000100014.151798.712802143.16260-0.252802.848401.78680HepG2UTP18
SPECC1LENSG00000100014.152336.163302013.046700.214702.457001.88510HepG2UTP3
SPECC1LENSG00000100014.151040.443201405.53950-0.433903.213802.43530HepG2XRN2
SPECC1LENSG00000100014.152137.645701703.445400.327505.786304.87040HepG2ZC3H8
SPECC1LENSG00000100014.15969.479401483.43220-0.613707.047505.11160K562ABCF1
SPECC1LENSG00000100014.15640.010701335.83940-1.0616028.1340026.41980K562AGGF1
SPECC1LENSG00000100014.151161.986901467.85920-0.337102.737701.76180K562AKAP8
SPECC1LENSG00000100014.15772.118801389.99500-0.8482013.0603011.48500K562AKAP8L
SPECC1LENSG00000100014.15708.749901279.03430-0.8517011.3053010.23700K562AQR
SPECC1LENSG00000100014.151198.812901458.42700-0.282802.705401.80260K562ATP5C1
SPECC1LENSG00000100014.151289.451501596.42250-0.308102.886001.67900K562CCDC124
SPECC1LENSG00000100014.151799.576301467.991000.293703.721502.98090K562DDX47
SPECC1LENSG00000100014.15553.72520724.98750-0.388802.545001.67280K562EFTUD2
SPECC1LENSG00000100014.151051.79790680.575800.627906.966805.67160K562EIF4A3
SPECC1LENSG00000100014.15449.33130634.17090-0.497103.995802.05730K562FASTKD2
SPECC1LENSG00000100014.15846.72750707.766900.258501.852001.33700K562FXR1
SPECC1LENSG00000100014.15887.624101084.62750-0.289202.508401.42690K562GLRX3
SPECC1LENSG00000100014.151108.219301542.83950-0.477305.205604.16430K562GRSF1
SPECC1LENSG00000100014.15526.70540757.74240-0.524704.629603.87620K562HNRNPC
SPECC1LENSG00000100014.15558.44160764.83350-0.453702.686001.67860K562IGF2BP2
SPECC1LENSG00000100014.151124.136601475.15480-0.392003.362102.44240K562KIF1C
SPECC1LENSG00000100014.15484.63070683.25340-0.495502.680601.76550K562KRR1
SPECC1LENSG00000100014.15985.38940803.789600.293802.150301.40490K562MAGOH
SPECC1LENSG00000100014.151090.892301412.06770-0.372302.906001.79710K562MAK16
SPECC1LENSG00000100014.151331.686401652.54280-0.311402.591001.71600K562MBNL1
SPECC1LENSG00000100014.15607.36450780.93470-0.362602.420401.60430K562METAP2
SPECC1LENSG00000100014.15873.652001158.31080-0.406902.250001.47450K562NAA15
SPECC1LENSG00000100014.15922.393701210.47980-0.392103.020002.15820K562PPIG
SPECC1LENSG00000100014.15545.41170705.49760-0.371302.186401.51530K562PRPF8
SPECC1LENSG00000100014.151104.674601378.54020-0.319502.417701.90230K562PUS1
SPECC1LENSG00000100014.15919.635201343.14110-0.546507.656706.70030K562RBM15
SPECC1LENSG00000100014.151066.448101280.86200-0.264302.981602.01570K562SRPK2
SPECC1LENSG00000100014.151088.97220838.104700.377703.495702.57340K562SYNCRIP
SPECC1LENSG00000100014.15528.07340694.49230-0.395202.586801.67830K562TRIM56
SPECC1LENSG00000100014.151193.607601457.78610-0.288503.377101.96480K562TROVE2
SPECC1LENSG00000100014.151120.491401440.91230-0.362903.166502.23620K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPECC1L is not available on ENCORE database.





8 RBPs can affect the splicing of SPECC1L :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPECC1LENSG00000100014.15chr22+246726672467277124666807246669512469816224698352-0.519000.006590.09120excludedK562SF3B4
SESPECC1LENSG00000100014.15chr22+246726672467277124666807246669512469816224698352-0.363000.001320.04602excludedK562PRPF8
SESPECC1LENSG00000100014.15chr22+246726672467277124666807246669512469816224698352-0.187000.000080.00231excludedHepG2U2AF1
SESPECC1LENSG00000100014.15chr22+2467266724672771246668072466695124698162246983520.515000.000080.01397includedK562FMR1
SESPECC1LENSG00000100014.15chr22+246726672467277124666807246669512469816224698352-0.144000.000010.00023excludedHepG2U2AF2
SESPECC1LENSG00000100014.15chr22+246726672467277124666807246669512469816224698352-0.400000.000080.00742excludedK562EFTUD2
SESPECC1LENSG00000100014.15chr22+246726672467277124666807246669512469816224698352-0.232000.000100.00481excludedHepG2SF3A3
SESPECC1LENSG00000100014.15chr22+246726672467277124666807246669512469816224698352-0.357000.000990.03755excludedK562TARDBP
MXESPECC1LENSG00000100014.15chr22+2467266724672771247092802470943424666807246669512471725524718886-0.063000.001650.031602includedHepG2U2AF1
MXESPECC1LENSG00000100014.15chr22+24698162246983522470928024709434246667852466695124717255247188860.282000.000690.025091includedK562EFTUD2
MXESPECC1LENSG00000100014.15chr22+2469816224698352247092802470943424666785246669512471725524718886-0.120000.000010.001572includedK562FMR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPECC1L is not avaliable on ENCORE database.