A1CF

General Information

Gene Name : A1CF
Gene ID : ENSG00000148584.14
Essential Gene : No

Functions

RNA modification
RNA stability & decay
RNA export

Localization

Not Available

Domains (AlphaFold: A1CF)

RRM

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	A1CF	ENSG00000148584.14	0.00	0.00	0.00	ENCSR000AEF
HepG2	A1CF	ENSG00000148584.14	37.52	47.84	42.68	ENCSR985KAT
K562	A1CF	ENSG00000148584.14	0.00	0.00	0.00	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
RNA Bind-n-Seq	RBNS: A1CF	ENCSR934TDK	A1CF	cell-free sample	Released		ENCSR866URJ

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
A1CF	A1CF		Released	ENCODE3

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for A1CF is not avaliable on ENCORE database.

The binding motifs of A1CF

Proteins bound to RNA

A1CF RNA is bound by 14 proteins.

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eCLIP assay for A1CF is not avaliable on ENCORE database.

14 proteins are bound to A1CF RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr10	52619563	52619622	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.67158	25.56347	HepG2	PRPF8
chr10	52629288	52629342	-	intron-Distal	5.44852	22.37507	HepG2	QKI
chr10	52580326	52580370	-	CDS,intron-Distal	4.72128	16.52049	HepG2	BCLAF1
chr10	52603747	52603791	-	CDS,intron-Distal,intron-Proximal	5.23581	16.08161	HepG2	BCLAF1
chr10	52623433	52623524	-	intron-Distal	5.80079	14.70924	HepG2	QKI
chr10	52627442	52627513	-	intron-Distal	4.02315	12.97728	HepG2	PTBP1
chr10	52629204	52629288	-	intron-Distal	4.79930	12.88973	HepG2	QKI
chr10	52587895	52587948	-	CDS,intron-Distal	4.55113	12.20601	HepG2	BCLAF1
chr10	52627224	52627317	-	intron-Distal	3.94521	11.26898	HepG2	HNRNPL
chr10	52580311	52580326	-	CDS,intron-Distal,intron-Proximal	5.63161	11.17302	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 51 entries

eCLIP assay for A1CF is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for A1CF is not available on ENCORE database.
108 RBPs can affect the levels of A1CF.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for A1CF is not available on ENCORE database.

108 RBPs can affect the gene expression of A1CF :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
A1CF	ENSG00000148584.10	794.44270	4403.39520	-2.47060	69.73570	66.90500	HepG2	FIP1L1
A1CF	ENSG00000148584.10	1319.00530	2936.41730	-1.15460	59.88030	57.96630	HepG2	ACO1
A1CF	ENSG00000148584.10	1169.05390	4505.84910	-1.94650	51.40380	49.55510	HepG2	AKAP1
A1CF	ENSG00000148584.10	6364.27450	3368.33940	0.91790	49.38610	47.87680	HepG2	SSB
A1CF	ENSG00000148584.10	7082.78690	3887.69740	0.86530	47.11940	45.68710	HepG2	SRSF1
A1CF	ENSG00000148584.10	10528.47200	4023.65040	1.38760	41.02400	39.04470	HepG2	HNRNPLL
A1CF	ENSG00000148584.10	442.69250	1455.21930	-1.71690	38.53360	35.91440	HepG2	UCHL5
A1CF	ENSG00000148584.10	1557.01650	3434.75510	-1.14140	33.09750	31.69410	HepG2	RBM22
A1CF	ENSG00000148584.10	6417.94140	2809.31350	1.19180	31.96890	30.31720	HepG2	DKC1
A1CF	ENSG00000148584.10	1496.44240	2907.62400	-0.95830	31.70320	30.01970	HepG2	CELF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 110 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for A1CF is not available on ENCORE database.

30 RBPs can affect the splicing of A1CF :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	A1CF	ENSG00000148584.10	chr10	-	52642232	52642465			52619601	52619745	52645340	52645435	0.09900	0.00000	0.00029	included	HepG2	HNRNPK
SE	A1CF	ENSG00000148584.10	chr10	-	52622648	52622741			52619601	52619745	52645340	52645387	0.16000	0.00000	0.00000	included	HepG2	U2AF2
A3SS	A1CF	ENSG00000148584.10	chr10	-	52573616	52573822			52573616	52573798	52575765	52576039	-0.83600	0.00000	0.00000	shorter	HepG2	U2AF2
MXE	A1CF	ENSG00000148584.10	chr10	-	52603747	52603882	52619601	52619745	52601621	52601752	52645340	52645435	-0.22400	0.00000	0.00000	2included	HepG2	U2AF1
MXE	A1CF	ENSG00000148584.10	chr10	-	52603747	52603882	52619601	52619745	52601621	52601752	52623792	52623840	0.23300	0.00000	0.00000	1included	HepG2	U2AF2
MXE	A1CF	ENSG00000148584.10	chr10	-	52603747	52603882	52610424	52610567	52601621	52601752	52619601	52619745	0.10800	0.00000	0.00030	1included	HepG2	DDX6
SE	A1CF	ENSG00000148584.10	chr10	-	52623792	52623840			52619601	52619745	52645340	52645435	0.08000	0.00001	0.02562	included	HepG2	SUB1
SE	A1CF	ENSG00000148584.10	chr10	-	52623792	52623840			52619601	52619745	52645340	52645435	0.13500	0.00001	0.00087	included	HepG2	PTBP1
SE	A1CF	ENSG00000148584.10	chr10	-	52623792	52623840			52619601	52619745	52645340	52645435	0.08100	0.00002	0.02630	included	HepG2	TRA2A
SE	A1CF	ENSG00000148584.10	chr10	-	52610424	52610567			52603747	52603882	52619601	52619745	0.12100	0.00002	0.00424	included	HepG2	DDX6

Showing 1 to 10 of 51 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

A1CF

General Information

Functions

Localization

Domains (AlphaFold: A1CF)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for A1CF is not avaliable on ENCORE database.

14 proteins are bound to A1CF RNA:

eCLIP assay for A1CF is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for A1CF is not available on ENCORE database.

108 RBPs can affect the gene expression of A1CF :

The Knockdown/knockout RNA-Seq assay for A1CF is not available on ENCORE database.

30 RBPs can affect the splicing of A1CF :

The Knockdown/knockout RNA-Seq assay for A1CF is not avaliable on ENCORE database.