DVL2

General Information

Gene Name       : DVL2
Gene ID             : ENSG00000004975.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DVL2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DVL2ENSG00000004975.113.2214.408.81ENCSR000AEF
HepG2DVL2ENSG00000004975.1136.2118.7227.46ENCSR985KAT
K562DVL2ENSG00000004975.1125.6322.8624.24ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DVL2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DVL2 RNA is bound by 18 proteins.  







eCLIP assay for DVL2 is not avaliable on ENCORE database.





18 proteins are bound to DVL2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1771290367129050-3'-UTR,intron-Distal3.699264.74241K562YBX3
chr1771287027128744-3'-UTR,intron-Distal,intron-Proximal5.193249.39648K562PABPC4
chr1771290077129036-3'-UTR,intron-Distal3.200144.37238K562YBX3
chr1771374827137598-5'-UTR,CDS,intron-Distal,intron-Proximal4.859694.88132HepG2RBM15
chr1771375447137660-5'-UTR,CDS,intron-Distal,intron-Proximal3.818135.30350K562HNRNPM
chr1771376147137713-5'-UTR,intron-Distal,intron-Proximal4.454834.82934K562RBM15
chr1771376377137705-5'-UTR,intron-Distal,intron-Proximal5.176904.39123K562GEMIN5
chr1771373497137404-5'-UTR,CDS,intron-Distal,intron-Proximal5.9599810.09256HepG2PRPF8
chr1771376357137708-5'-UTR,intron-Distal,intron-Proximal4.566683.99162HepG2DDX3X
chr1771306847130734-CDS,intron-Distal,intron-Proximal4.780788.77485HepG2PRPF8
chr1771308217130858-CDS,intron-Distal,intron-Proximal4.079723.56076K562BUD13
chr1771310827131135-CDS,intron-Distal,intron-Proximal5.294908.72621HepG2PRPF8
chr1771309727130999-CDS,intron-Distal,intron-Proximal3.600897.64107HepG2PPIG
chr1771304037130460-CDS,intron-Distal,intron-Proximal4.641266.33775HepG2GRWD1
chr1771297477129782-CDS,intron-Distal4.627125.27053HepG2PPIG
chr1771308207130854-CDS,intron-Distal3.744188.19289HepG2PPIG
chr1771333137133372-CDS,intron-Distal,intron-Proximal4.730269.10443HepG2PRPF8
chr1771336107133654-CDS,intron-Distal4.909236.16445HepG2PPIG
chr1771332137133267-CDS,intron-Distal,intron-Proximal3.725966.50179HepG2BUD13
chr1771313607131428-CDS,intron-Distal,intron-Proximal4.569206.59856K562SF3B4
chr1771299347130038-CDS,intron-Distal,intron-Proximal4.665979.84788HepG2SF3A3
chr1771340457134113-CDS,intron-Distal,intron-Proximal3.160688.74985HepG2PPIG
chr1771299097129981-CDS,intron-Distal,intron-Proximal4.484869.32426HepG2U2AF2
chr1771310627131141-CDS,intron-Distal,intron-Proximal5.006989.46915K562AQR
chr1771374097137460-CDS,intron-Distal,intron-Proximal3.867413.34184HepG2GRWD1
chr1771340647134107-CDS,intron-Distal,intron-Proximal4.127824.21087HepG2GRWD1
chr1771303957130438-CDS,intron-Distal,intron-Proximal3.357195.58370HepG2PPIG
chr1771313627131418-CDS,intron-Distal,intron-Proximal4.464483.31322HepG2SF3B4
chr1771303857130410-CDS,intron-Distal,intron-Proximal4.643939.78712K562AQR
chr1771305217130578-CDS,intron-Distal,intron-Proximal3.394994.25541HepG2GRWD1
chr1771312947131336-CDS,intron-Distal,intron-Proximal3.176095.74131HepG2PPIG
chr1771334397133477-CDS,intron-Distal,intron-Proximal4.271417.72847HepG2PPIG
chr1771322607132300-CDS,intron-Distal,intron-Proximal4.148516.81564HepG2PRPF8
chr1771299147129992-CDS,intron-Distal,intron-Proximal4.2461810.16714K562AQR
chr1771305137130580-CDS,intron-Distal,intron-Proximal5.436589.71053HepG2PPIG
chr1771374437137551-CDS,intron-Distal,intron-Proximal4.307364.13543HepG2FXR2
chr1771303657130414-CDS,intron-Distal,intron-Proximal3.227685.89323HepG2PRPF8
chr1771323067132322-CDS,intron-Distal4.442153.20743HepG2PPIG
chr1771292387129470-CDS,intron-Distal,intron-Proximal3.001895.72918HepG2HNRNPK
chr1771305197130576-CDS,intron-Distal,intron-Proximal3.575633.02850K562YBX3
chr1771324637132513-CDS,intron-Distal,intron-Proximal3.995614.41267HepG2PPIG
chr1771310597131213-CDS,intron-Distal,intron-Proximal4.2201311.40067HepG2AQR
chr1771333747133427-CDS,intron-Distal,intron-Proximal3.288097.20311HepG2PPIG
chr1771325897132667-CDS,intron-Distal,intron-Proximal5.1643313.67886HepG2EFTUD2
chr1771333157133367-CDS,intron-Distal,intron-Proximal4.403513.74254HepG2SF3B4
chr1771297477129791-CDS,intron-Distal4.094978.57807K562YBX3
chr1771326237132704-CDS,intron-Distal,intron-Proximal5.1592517.17028HepG2PRPF8
chr1771324317132480-CDS,intron-Distal,intron-Proximal5.360309.06713HepG2PRPF8
chr1771310797131201-CDS,intron-Distal,intron-Proximal3.490665.37697K562EFTUD2
chr1771328017132865-intron-Distal,intron-Proximal4.8235012.86254HepG2EFTUD2
chr1771326037132663-intron-Distal,intron-Proximal4.444405.07796HepG2SF3B4
chr1771328107132877-intron-Distal,intron-Proximal5.556757.63570K562AQR
chr1771327867132883-intron-Distal,intron-Proximal3.9352013.85817HepG2PRPF8
chr1771328057132870-intron-Distal,intron-Proximal5.285729.24065HepG2AQR
chr1771328147132877-intron-Distal,intron-Proximal3.891523.48722HepG2PRPF4
chr1771332707133315-intron-Distal,intron-Proximal3.903516.98946HepG2SF3B4
chr1771312477131292-intron-Distal,intron-Proximal4.528434.62947HepG2AQR
chr1771332657133307-intron-Distal,intron-Proximal3.951964.69223K562SF3B4
chr1771332797133342-intron-Distal,intron-Proximal5.053149.24251HepG2EFTUD2
chr1771303377130360-intron-Distal,intron-Proximal5.172064.86944K562AQR
chr1771302657130321-intron-Distal,intron-Proximal3.065496.35819HepG2EFTUD2
chr1771335107133589-intron-Distal,intron-Proximal3.659119.23918HepG2PRPF8
chr1771311357131199-intron-Distal,intron-Proximal4.7278410.92835HepG2PRPF8
chr1771303207130396-intron-Distal,intron-Proximal3.513977.42773K562BUD13
chr1771311067131183-intron-Distal,intron-Proximal4.370984.77050HepG2SF3B4
chr1771333007133332-intron-Distal,intron-Proximal3.933473.20629HepG2BUD13
chr1771303607130385-intron-Distal,intron-Proximal5.4672712.21485K562AQR
chr1771311157131203-intron-Distal,intron-Proximal6.1800212.33104HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DVL2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DVL2 is not available on ENCORE database.

  • 88 RBPs can affect the levels of DVL2.  








The Knockdown/knockout RNA-Seq assay for DVL2 is not available on ENCORE database.





88 RBPs can affect the gene expression of DVL2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DVL2ENSG00000004975.7578.61510908.59150-0.6510010.982509.93900HepG2ACO1
DVL2ENSG00000004975.7779.24440557.145700.483903.648902.52360HepG2ADAR
DVL2ENSG00000004975.7768.744301273.38690-0.728106.735805.94720HepG2AKAP1
DVL2ENSG00000004975.7922.326801224.56220-0.408905.129604.24160HepG2AUH
DVL2ENSG00000004975.7444.75250668.83380-0.588605.247404.22660HepG2CALR
DVL2ENSG00000004975.7754.46830908.33070-0.267802.560401.91610HepG2CKAP4
DVL2ENSG00000004975.7350.69460600.80220-0.776705.116503.07900HepG2CSTF2T
DVL2ENSG00000004975.71089.10000908.306200.261802.701901.96740HepG2DAZAP1
DVL2ENSG00000004975.7863.269701219.66900-0.498603.972003.23400HepG2DDX3X
DVL2ENSG00000004975.7514.12620695.92090-0.436802.617901.86320HepG2DDX55
DVL2ENSG00000004975.7301.21780555.53530-0.883103.635702.51780HepG2DDX59
DVL2ENSG00000004975.71077.25880869.259500.309403.049002.34190HepG2DKC1
DVL2ENSG00000004975.7770.52230561.011300.457702.760502.05830HepG2DNAJC21
DVL2ENSG00000004975.7713.77760556.074400.360103.697602.96310HepG2DNAJC2
DVL2ENSG00000004975.7407.16600647.09410-0.668405.662604.07200HepG2EFTUD2
DVL2ENSG00000004975.7310.55290595.76320-0.939907.790205.97930HepG2AGO1
DVL2ENSG00000004975.7460.37650630.13580-0.452802.900701.97830HepG2EIF3D
DVL2ENSG00000004975.7632.60180896.10630-0.502405.953504.80810HepG2EIF4G1
DVL2ENSG00000004975.71050.467301405.97550-0.420506.091005.25840HepG2ETF1
DVL2ENSG00000004975.7450.86520616.35780-0.451103.234102.00790HepG2FASTKD2
DVL2ENSG00000004975.7477.732001162.53120-1.2830017.5730015.92240HepG2FIP1L1
DVL2ENSG00000004975.7795.609501041.82220-0.389002.486501.85390HepG2G3BP1
DVL2ENSG00000004975.7712.19880867.40630-0.284402.562901.61670HepG2HDGF
DVL2ENSG00000004975.7311.76760659.03050-1.079903.210101.70860HepG2HLTF
DVL2ENSG00000004975.7842.58860566.386100.572905.421804.55960HepG2HNRNPA1
DVL2ENSG00000004975.7664.86580834.76300-0.328302.940901.98100HepG2HNRNPA2B1
DVL2ENSG00000004975.71028.10020827.395200.313203.607302.84380HepG2HNRNPL
DVL2ENSG00000004975.7746.24450529.181700.495803.401402.71130HepG2HNRNPLL
DVL2ENSG00000004975.7869.06960710.548500.290402.057101.42650HepG2IGF2BP1
DVL2ENSG00000004975.7445.69310659.47150-0.565302.534801.52570HepG2METAP2
DVL2ENSG00000004975.7576.41440940.79160-0.706808.498107.15020HepG2MSI2
DVL2ENSG00000004975.7851.587501156.51120-0.441603.105802.43710HepG2NCBP2
DVL2ENSG00000004975.7570.00450227.981001.322004.447902.08080HepG2NUFIP2
DVL2ENSG00000004975.7495.44520619.46720-0.322302.403901.61040HepG2PARN
DVL2ENSG00000004975.7694.71790558.198100.315502.390901.70150HepG2PPIL4
DVL2ENSG00000004975.7250.64560536.70050-1.0985011.181109.71110HepG2PRPF8
DVL2ENSG00000004975.71041.75790859.775100.276901.846901.34640HepG2PUF60
DVL2ENSG00000004975.71061.42140912.691600.217702.103501.57260HepG2PUM1
DVL2ENSG00000004975.71201.70950925.450100.376805.098704.30850HepG2PUS1
DVL2ENSG00000004975.7734.480201182.94010-0.6876010.368109.26830HepG2QKI
DVL2ENSG00000004975.7857.410401175.13240-0.454805.282704.62410HepG2RBM22
DVL2ENSG00000004975.7830.442701073.61230-0.370503.061702.35640HepG2RBM25
DVL2ENSG00000004975.7848.55980587.185600.531103.152002.01800HepG2RCC2
DVL2ENSG00000004975.7912.155401215.60660-0.414305.099604.40210HepG2NELFE
DVL2ENSG00000004975.7389.79720530.89360-0.445702.417101.67770HepG2RRP9
DVL2ENSG00000004975.7433.57310615.37210-0.505203.601302.52420HepG2SERBP1
DVL2ENSG00000004975.7695.50220221.531401.650406.703004.43980HepG2SF1
DVL2ENSG00000004975.7576.35450215.320901.420404.703802.73900HepG2SFPQ
DVL2ENSG00000004975.71038.77770824.395200.333403.938503.12450HepG2SLBP
DVL2ENSG00000004975.7452.78570198.350501.190703.677802.11870HepG2SNRNP200
DVL2ENSG00000004975.7984.826401327.26350-0.430506.349705.67510HepG2SRFBP1
DVL2ENSG00000004975.7786.766401186.99160-0.593309.653708.89110HepG2SRSF1
DVL2ENSG00000004975.7992.50840848.905500.225401.845701.32010HepG2SRSF5
DVL2ENSG00000004975.7827.53730965.69510-0.222701.823801.35810HepG2SRSF9
DVL2ENSG00000004975.71478.561201152.369800.359505.012904.36230HepG2SSB
DVL2ENSG00000004975.71148.10620965.437000.249902.432701.84240HepG2SUCLG1
DVL2ENSG00000004975.7702.110501066.96020-0.603708.315807.42840HepG2TAF15
DVL2ENSG00000004975.7766.94470980.34240-0.354202.967302.10420HepG2TIA1
DVL2ENSG00000004975.7882.33680608.099100.536905.751205.08030HepG2TIAL1
DVL2ENSG00000004975.71155.46920839.967800.460003.634602.61850HepG2TUFM
DVL2ENSG00000004975.7773.96230994.42140-0.361602.456701.86220HepG2U2AF1
DVL2ENSG00000004975.7767.86310966.59890-0.332103.261502.62070HepG2UTP3
DVL2ENSG00000004975.7914.95250681.924000.424002.434301.75080HepG2XRN2
DVL2ENSG00000004975.7529.41570644.73720-0.284302.231501.61910HepG2ZC3H8
DVL2ENSG00000004975.7801.792101101.10460-0.457707.388106.60590HepG2ZNF622
DVL2ENSG00000004975.7533.51340782.64450-0.552804.734703.14140K562AARS
DVL2ENSG00000004975.71423.686101097.177400.375702.848202.27250K562AGGF1
DVL2ENSG00000004975.71517.445101141.650000.410403.745102.98240K562AKAP8L
DVL2ENSG00000004975.71453.244401198.305300.278202.849401.61890K562DDX21
DVL2ENSG00000004975.71030.15800823.604300.322702.524801.52990K562DDX3X
DVL2ENSG00000004975.7588.31630770.55480-0.389302.285301.35570K562EIF3D
DVL2ENSG00000004975.71600.703101894.80850-0.243302.657801.73520K562EIF4G2
DVL2ENSG00000004975.7371.55740743.57490-1.0009011.197308.76420K562FKBP4
DVL2ENSG00000004975.7649.92240894.83120-0.461305.089204.30340K562FXR1
DVL2ENSG00000004975.799.75010355.66040-1.834108.547707.16030K562G3BP2
DVL2ENSG00000004975.7615.82070856.23760-0.475504.101803.39000K562HNRNPC
DVL2ENSG00000004975.7909.31490610.476300.574702.553201.58000K562IGF2BP2
DVL2ENSG00000004975.71226.95610868.544100.498304.153702.28180K562LIN28B
DVL2ENSG00000004975.71477.958201254.239700.236703.059002.27750K562NSUN2
DVL2ENSG00000004975.71082.24510657.551000.718802.966601.93110K562PABPN1
DVL2ENSG00000004975.7884.86780626.939300.497004.988703.11370K562PCBP1
DVL2ENSG00000004975.7423.87220570.40840-0.428402.758301.77950K562PCBP2
DVL2ENSG00000004975.71077.94820735.173800.552002.622301.82640K562PPIG
DVL2ENSG00000004975.7328.83120700.56150-1.091209.220507.84650K562PRPF8
DVL2ENSG00000004975.71529.653002067.32430-0.434604.535003.49440K562PUF60
DVL2ENSG00000004975.71753.852302199.31240-0.326504.013402.70620K562PUM1
DVL2ENSG00000004975.71561.762101132.295700.463803.760003.14060K562PUS1
DVL2ENSG00000004975.71381.585801103.175200.324603.139502.51370K562RBM15
DVL2ENSG00000004975.71473.358601237.696200.251402.297001.54820K562SF3A3
DVL2ENSG00000004975.71404.00900732.650600.938304.566302.72390K562SFPQ
DVL2ENSG00000004975.7896.90170664.071900.433503.176902.05950K562SRFBP1
DVL2ENSG00000004975.7829.80310624.985000.408803.028201.91430K562SRSF4
DVL2ENSG00000004975.7789.87680576.936200.453103.487402.28470K562SRSF5
DVL2ENSG00000004975.7666.99890957.41030-0.521505.774904.58120K562SYNCRIP
DVL2ENSG00000004975.7171.84230349.09110-1.022503.188401.58420K562TAF15
DVL2ENSG00000004975.7902.13420618.033100.545604.772603.83500K562TARDBP
DVL2ENSG00000004975.7776.77710596.189100.381602.604501.81290K562TIA1
DVL2ENSG00000004975.71104.91750738.411600.581305.137803.82530K562TIAL1
DVL2ENSG00000004975.71083.11610784.554300.465104.271703.04020K562TRIM56
DVL2ENSG00000004975.7212.05070355.75370-0.746503.311902.43530K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DVL2 is not available on ENCORE database.





15 RBPs can affect the splicing of DVL2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDVL2ENSG00000004975.7chr17-713129571313637130973713110271322877132364-0.072000.001200.01421excludedK562AQR
A3SSDVL2ENSG00000004975.7chr17-7132696713279471326967132766713290671329970.125000.000520.08835longerHepG2TAF15
A3SSDVL2ENSG00000004975.7chr17-7133376713352871333767133474713360371337490.118000.000000.00000longerK562AQR
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.115000.000000.00001includedK562PUS1
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.067000.000380.07038includedK562DHX30
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.083000.000830.03357includedK562HNRNPUL1
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.079000.000330.00521includedK562AGGF1
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.058000.005680.05581includedHepG2QKI
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.153000.000000.00000includedK562AKAP8L
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.065000.012240.09211includedHepG2U2AF1
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.120000.000000.00006includedK562RBM15
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.209000.002990.04024includedK562U2AF2
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.051000.003210.03610includedHepG2NCBP2
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.066000.006680.05660includedHepG2RBM22
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.054000.005350.08885includedHepG2PTBP1
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.115000.000030.00080includedK562UTP18
RIDVL2ENSG00000004975.7chr17-7133603713411671336037133749713404671341160.101000.000140.00108includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DVL2 is not avaliable on ENCORE database.