XRCC1

General Information

Gene Name       : XRCC1
Gene ID             : ENSG00000073050.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: XRCC1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878XRCC1ENSG00000073050.1110.5622.1916.38ENCSR000AEF
HepG2XRCC1ENSG00000073050.1130.7119.4125.06ENCSR985KAT
K562XRCC1ENSG00000073050.1126.7524.8525.80ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for XRCC1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • XRCC1 RNA is bound by 6 proteins.  







eCLIP assay for XRCC1 is not avaliable on ENCORE database.





6 proteins are bound to XRCC1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194405622744056283-3'-UTR,CDS,intron-Distal,intron-Proximal3.819343.31827HepG2GRWD1
chr194405623644056324-3'-UTR,CDS,intron-Distal,intron-Proximal3.059624.30396K562UCHL5
chr194407955244079637-5'-UTR,CDS,intron-Distal3.038903.16816HepG2NCBP2
chr194404759744047651-CDS,intron-Distal3.395833.69481K562UCHL5
chr194405002144050081-CDS,intron-Distal3.770003.32039HepG2PPIG
chr194406507044065130-CDS,intron-Distal,intron-Proximal3.849944.96634HepG2PPIG
chr194405598444056048-intron-Distal4.901096.36200HepG2PTBP1
chr194405589044055984-intron-Distal,intron-Proximal3.340596.07207HepG2PTBP1
chr194407285844072977-intron-Distal4.777175.14122HepG2PCBP2
chr194405597044056066-intron-Distal4.439646.59655K562PTBP1
chr194405588144055943-intron-Distal,intron-Proximal3.843324.67922K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for XRCC1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for XRCC1 is not available on ENCORE database.

  • 92 RBPs can affect the levels of XRCC1.  








The Knockdown/knockout RNA-Seq assay for XRCC1 is not available on ENCORE database.





92 RBPs can affect the gene expression of XRCC1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
XRCC1ENSG00000073050.7421.94790631.56740-0.581906.474505.62420HepG2ACO1
XRCC1ENSG00000073050.7632.96000458.478100.465203.129202.07340HepG2ADAR
XRCC1ENSG00000073050.7478.21620634.43090-0.407803.654902.78640HepG2AKAP8L
XRCC1ENSG00000073050.7779.22070947.61160-0.282302.311201.67480HepG2AUH
XRCC1ENSG00000073050.7280.55090692.27960-1.3031018.8659017.51020HepG2BOP1
XRCC1ENSG00000073050.7452.48610689.80260-0.608305.197204.18070HepG2CALR
XRCC1ENSG00000073050.7439.45080631.30540-0.522603.023502.33530HepG2CKAP4
XRCC1ENSG00000073050.7608.08750799.21080-0.394303.179801.99260HepG2CPSF7
XRCC1ENSG00000073050.7411.20840529.52890-0.364802.007701.41860HepG2DDX21
XRCC1ENSG00000073050.7691.37190967.20230-0.484403.517302.82140HepG2DDX3X
XRCC1ENSG00000073050.7632.10030833.02770-0.398202.931901.59870HepG2DDX47
XRCC1ENSG00000073050.7590.84120831.09700-0.492203.144202.48960HepG2DDX6
XRCC1ENSG00000073050.7729.91190604.206600.272601.982801.39470HepG2DKC1
XRCC1ENSG00000073050.7633.14020457.591200.468405.229804.37810HepG2DNAJC2
XRCC1ENSG00000073050.7340.31250488.04640-0.520202.654701.57320HepG2AGO1
XRCC1ENSG00000073050.7425.68030798.70530-0.907909.496908.43760HepG2EIF2S1
XRCC1ENSG00000073050.7323.23350534.40770-0.725405.333204.10770HepG2EIF3D
XRCC1ENSG00000073050.7395.27060882.54310-1.1588014.2692012.84280HepG2EIF4A3
XRCC1ENSG00000073050.7411.27910859.50890-1.063409.154007.94190HepG2EIF4B
XRCC1ENSG00000073050.7791.546601087.98490-0.458906.068305.23640HepG2ETF1
XRCC1ENSG00000073050.7309.79930502.88620-0.698902.892501.48220HepG2HLTF
XRCC1ENSG00000073050.7292.19450466.08610-0.673704.672003.86180HepG2HNRNPA1
XRCC1ENSG00000073050.7528.43290725.55540-0.457404.345303.21860HepG2HNRNPA2B1
XRCC1ENSG00000073050.7381.98010518.43610-0.440702.570301.89980HepG2HNRNPC
XRCC1ENSG00000073050.7492.68580687.51930-0.480703.176502.50770HepG2HNRNPLL
XRCC1ENSG00000073050.7778.55480515.008400.596108.199507.19630HepG2HNRNPU
XRCC1ENSG00000073050.7363.12520839.71370-1.2094016.4832015.00050HepG2IGF2BP2
XRCC1ENSG00000073050.7678.62610526.063800.367303.646702.81510HepG2ILF2
XRCC1ENSG00000073050.7677.971901072.79080-0.662105.200704.04960HepG2LARP4
XRCC1ENSG00000073050.7450.21500891.12520-0.9850011.5364010.23200HepG2MAGOH
XRCC1ENSG00000073050.7511.49660896.05360-0.808907.455106.45800HepG2MATR3
XRCC1ENSG00000073050.7555.82050917.11260-0.722506.694205.72790HepG2NCBP2
XRCC1ENSG00000073050.7494.35890816.52770-0.723906.632105.52220HepG2PABPC4
XRCC1ENSG00000073050.7343.09310833.20260-1.2801029.7485028.11900HepG2PCBP1
XRCC1ENSG00000073050.7301.25270495.88920-0.719003.675102.48590HepG2PCBP2
XRCC1ENSG00000073050.7593.95580459.346100.370702.833702.08900HepG2PPIL4
XRCC1ENSG00000073050.7913.46480678.042900.429904.830203.83940HepG2PRPF4
XRCC1ENSG00000073050.7271.78020397.92940-0.550103.371202.48760HepG2PRPF8
XRCC1ENSG00000073050.7621.42900847.82510-0.448204.873604.19110HepG2PTBP1
XRCC1ENSG00000073050.7600.74360747.27890-0.314901.829601.33140HepG2PUF60
XRCC1ENSG00000073050.7744.04810918.19350-0.303402.292901.71450HepG2QKI
XRCC1ENSG00000073050.7266.05200478.36460-0.846403.656302.84890HepG2RAVER1
XRCC1ENSG00000073050.7394.85650909.35410-1.2035024.5179023.28150HepG2RBM22
XRCC1ENSG00000073050.7461.04080833.32790-0.8540011.3116010.00760HepG2RBM25
XRCC1ENSG00000073050.7452.43300647.19860-0.516503.796802.62370HepG2RBM27
XRCC1ENSG00000073050.7767.56060943.53940-0.297802.536502.01550HepG2NELFE
XRCC1ENSG00000073050.7413.36340697.88890-0.755607.792406.73680HepG2RPLP0
XRCC1ENSG00000073050.7319.25270470.22830-0.558702.597701.68080HepG2RPS10
XRCC1ENSG00000073050.7356.49090520.02950-0.544704.043903.31510HepG2RPS19
XRCC1ENSG00000073050.7429.12160596.84430-0.476003.475202.57820HepG2RPS2
XRCC1ENSG00000073050.7298.28270484.28860-0.699202.173501.46410HepG2RPS3A
XRCC1ENSG00000073050.7169.27350393.61290-1.2174010.672209.28220HepG2RRP9
XRCC1ENSG00000073050.7325.50590521.88740-0.681105.530104.21380HepG2SERBP1
XRCC1ENSG00000073050.7604.14960835.78280-0.468202.534601.88920HepG2SF3A3
XRCC1ENSG00000073050.7285.31890680.50130-1.2540017.1237015.52970HepG2SF3B1
XRCC1ENSG00000073050.7471.82890882.67690-0.9036016.2240014.97330HepG2SF3B4
XRCC1ENSG00000073050.7665.66760534.846500.315602.745902.10370HepG2SMN1
XRCC1ENSG00000073050.7542.06040757.17950-0.482202.225801.52870HepG2SNRNP70
XRCC1ENSG00000073050.7504.794101027.08200-1.0248025.3536024.23540HepG2SRFBP1
XRCC1ENSG00000073050.7635.88860921.33110-0.534906.942606.27610HepG2SRSF1
XRCC1ENSG00000073050.7439.27470732.24180-0.737205.340003.91000HepG2SRSF3
XRCC1ENSG00000073050.7502.40970636.43870-0.341202.880002.17150HepG2SRSF7
XRCC1ENSG00000073050.7367.60070749.55840-1.0279020.2169018.97620HepG2SRSF9
XRCC1ENSG00000073050.7301.47350447.09220-0.568502.438201.31220HepG2SUB1
XRCC1ENSG00000073050.7501.64660661.68410-0.399503.191002.18620HepG2SUPT6H
XRCC1ENSG00000073050.7354.95410513.73250-0.533403.288302.55810HepG2SUPV3L1
XRCC1ENSG00000073050.7223.97760344.29780-0.620303.426802.32830HepG2TFIP11
XRCC1ENSG00000073050.7313.88730500.42110-0.672905.947505.26660HepG2TIAL1
XRCC1ENSG00000073050.7497.64970838.37580-0.752508.209307.12840HepG2U2AF1
XRCC1ENSG00000073050.7583.66890741.21370-0.344703.171902.43460HepG2UPF1
XRCC1ENSG00000073050.7399.89050715.60950-0.8396012.9827011.82700HepG2UTP3
XRCC1ENSG00000073050.7910.19680669.168300.443705.591404.68790HepG2ZC3H8
XRCC1ENSG00000073050.7467.28280815.19020-0.8028015.5380014.50510HepG2ZNF622
XRCC1ENSG00000073050.71787.908701497.057100.256003.015002.42580K562AGGF1
XRCC1ENSG00000073050.7563.371801033.92630-0.8760010.548409.51290K562AQR
XRCC1ENSG00000073050.71079.37290768.689400.489605.173404.10780K562CPSF6
XRCC1ENSG00000073050.71067.56010851.273400.326503.116402.36030K562EIF2S2
XRCC1ENSG00000073050.7360.81750563.20060-0.642402.318901.38110K562EIF3D
XRCC1ENSG00000073050.71146.59630895.216600.356903.112401.76400K562EXOSC5
XRCC1ENSG00000073050.7535.92080675.11590-0.333102.472101.89340K562FXR1
XRCC1ENSG00000073050.7104.82430330.01240-1.654504.414003.47670K562G3BP2
XRCC1ENSG00000073050.7978.92270733.900600.415503.321602.45330K562GPKOW
XRCC1ENSG00000073050.7676.85660974.86660-0.526405.636804.12350K562HNRNPA1
XRCC1ENSG00000073050.7943.99810719.009100.392703.054001.84920K562HNRNPF
XRCC1ENSG00000073050.71378.539001115.484100.305402.037401.34990K562HSPD1
XRCC1ENSG00000073050.7811.17500553.767200.550602.845001.80190K562IGF2BP2
XRCC1ENSG00000073050.7934.48560716.372500.383403.092402.16460K562METAP2
XRCC1ENSG00000073050.71747.095201158.944800.592002.461501.54130K562PABPN1
XRCC1ENSG00000073050.7383.74690517.38360-0.431102.291601.40630K562PCBP2
XRCC1ENSG00000073050.71073.94530873.379600.298102.217701.50040K562POLR2G
XRCC1ENSG00000073050.71069.57070778.351900.458404.236702.88480K562SAFB
XRCC1ENSG00000073050.72046.215201291.978200.663302.683501.40780K562SFPQ
XRCC1ENSG00000073050.7802.76970624.406200.362402.433701.48720K562SRFBP1
XRCC1ENSG00000073050.7764.47470560.586200.447403.222802.45960K562TARDBP
XRCC1ENSG00000073050.7839.45180540.774900.634304.879103.74590K562TIA1
XRCC1ENSG00000073050.7794.68540530.896600.581904.213302.81810K562TRA2A
XRCC1ENSG00000073050.7929.71520737.692100.333702.299701.44940K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for XRCC1 is not available on ENCORE database.





4 RBPs can affect the splicing of XRCC1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEXRCC1ENSG00000073050.7chr19-440650614406517244058797440589564407906144079154-0.165000.003260.04988excludedK562HNRNPC
A3SSXRCC1ENSG00000073050.7chr19-440569484405705444056948440569954405755244057664-0.069000.000450.09743shorterK562DROSHA
RIXRCC1ENSG00000073050.7chr19-4405694844057243440569484405706044057133440572430.091000.001130.01378includedHepG2RBM22
RIXRCC1ENSG00000073050.7chr19-440569484405724344056948440570604405713344057243-0.080000.006110.08393excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for XRCC1 is not avaliable on ENCORE database.